Name ____________________________________ Hr _____ Unit Test Review – Topic 10: GENETICS Directions: Use your resources (notes, class work, labs, practice quiz questions in binder; textbook; rufuskingbiology.wikispaces.com) to complete the following review packet. We will use our limited class review time to discuss tough questions, but you will need to complete most of your review outside of class. 10.1 Meiosis 10.1.1 Assessment statement Example Questions Describe the behaviour of the chromosomes in the phases of meiosis. A cell replicates its DNA and then starts to divide by meiosis. What is the expected arrangement of chromosomes if crossing over has taken place between the two genes shown? A. B. C. D. Answer is D. 10.1.2 Outline the formation of chiasmata in Synapsis brings together homologous chromosomes, each the process of crossing over. composed of identical sister chromatids. Non-sister chromatids intertwine and break at the same location, then reattach to produce new combinations of alleles (recombinants). 10.1.3 Explain how meiosis results in an Explain how meiosis results in great genetic variety effectively infinite genetic variety in among gametes. (8) gametes through crossing over in homologous chromosomes form tetrads / bivalents / prophase I and random orientation in pairs / undergo synapsis; metaphase I. crossing over; during prophase I; exchange of DNA / genes / alleles between (non-sister) chromatids / chromosomes; description / diagram of chiasma; new combinations of maternal and paternal genes / alleles / DNA; bivalents / homologous chromosomes orient / align themselves on equator randomly; during metaphase I; orientation of one homologous pair of chromosomes is independent of others; homologous chromosomes separate / move to opposite poles; independent assortment(of unlinked genes); leads to 2n / 223 possible gametes (without crossing Name ____________________________________ Hr _____ over); additional variation when chromatids separate in second division; 10.1.4 State Mendel’s law of independent assortment. When gametes are formed, the separation of one pair of alleles between the daughter cells is independent of the separation of another pair of alleles. (Just because one allele from a parent is passed on in a gamete, doesn’t mean any other specific allele will be passed on.) 10.1.5 Explain the relationship between Mendel’s law of independent assortment and meiosis. Explain the relationship between Mendel’s law of segregation and meiosis. (3) law of segregation states that one half of the alleles enter one gamete and the other half enter the other gamete; meiosis reduces the chromosome number by half / diploid to haploid; homologues carrying alleles separate (in anaphase I); end result is four cells, half with one allele / homologue and the other half with the other allele; 10.2 Dihybrid Crosses and Gene Linkage Assessment statement Example Questions 10.2.1 Calculate and predict the genotypic and phenotypic ratio of offspring of dihybrid crosses involving unlinked autosomal genes. In garden peas, the pairs of alleles coding for seed shape and seed colour are unlinked. The allele for smooth seeds (S) is dominant over the allele for wrinkled seeds (s). The allele for yellow seeds (Y) is dominant over the allele for green seeds (y). If a plant of genotype Ssyy is crossed with a plant of genotype ssYy, which offspring are recombinants? A. SsYy and Ssyy B. SsYy and ssYy C. SsYy and ssyy D. Ssyy and ssYy 10.2.2 Distinguish between autosomes and sex chromosomes. What is a difference between autosomes and sex chromosomes? A. Autosomes are not found in gametes but sex chromosomes are. B. Sex chromosomes are found in animal cells and autosomes are found in plant cells. C. Autosomes are diploid and sex chromosomes are haploid. D. Sex chromosomes determine gender and autosomes do not. 10.2.3 Explain how crossing over What are the possible outcomes of recombination? Name ____________________________________ Hr _____ between non-sister chromatids of a homologous pair in prophase I can result in an exchange of alleles. I. A different combination of unlinked genes not seen in the parents II. A different combination of linked genes not seen in the parents III. The same combination of genes seen in the parents A. I and II only B. I and III only C. II and III only D. I, II and III 10.2.4 Define linkage group. What constitutes a linkage group? A. Genes whose loci are on different chromosomes B. Genes carried on the same chromosome C. Genes controlling a polygenic characteristic D. Genes for the inheritance of ABO blood groups 10.2.5 Explain an example of a cross between two linked genes. Using an example you have studied, explain a cross between two linked genes, including the way in which recombinants are produced. (9) linked genes occur on the same chromosome / chromatid; genes (tend to be) inherited together / not separated / do not segregate independently; non-Mendelian ratio / not 9:3:3:1 / 1:1:1:1; Real example of two linked genes; Award [1] for each of the following examples of a cross between two linked genes. key for alleles involved in the example of a cross; homozygous parental genotypes and phenotypes shown; F1 genotype and phenotype shown / double heterozygote genotype and phenotype; possible F2 genotypes and phenotypes shown; recombinants identified; recombinants due to crossing over; in prophase I of meiosis; diagram / explanation of mutual exchange of parts of chromatids during crossing over; 10.2.6 Identify which of the offspring are Recombinants of linked genes are those combinations of genes recombinants in a dihybrid cross not found in parents involving linked genes. For example, in a test cross of a heterozygous fruit fly (grey bodied, normal wings) with a homozygous recessive mutant (black bodied, vestigial wings), the recombinants would be the grey bodied, vestigial winged offspring and the black bodied, normal winged offspring. Parents: GW x gw Recominbinants: Gw, gW gw gw gw gw Name ____________________________________ Hr _____ 10.3 Polygenic Inheritance Assessment statement Example Questions 10.3.1 Define polygenic inheritance. 10.3.2 Explain that polygenic inheritance A polygenic character is controlled by two genes each can contribute to continuous with two alleles. How many different possible variation using two examples, one of genotypes are there for this character? which must be human skin colour. A. 2 B. 4 C. 9 – XXYY, XXYy, XXyy, XxYY, XxYy, Xxyy, xxYY, xxYy, xxyy D. 16