Arterial stiffne
SELF-ESTEEM VARIABILITY AND ARTERIAL STIFFNESS 1
SUPPLEMENTAL MATERIAL
0.00
0
15
-0.10
Supplementary material on RHI:
-0.20
Itamar’s algorithm calculates RHI as the ratio of the average post-occlusion
PWA to the
average baseline PWA. Post-occlusion is defined as the average PWA from 1.5 to 2.5 minutes
after cuff deflation (Tierney et al., 2009). Baseline is defined as the average-0.30
PWA for the final
2.5 minutes of the 5 minute baseline period, excluding the 20 secondsinbefore
SD unitsocclusion. In order
to reduce error from potential systemic changes, the ratio is normalized to the corresponding
signal recorded from the non-occluded arm. Higher ratio values indicate greater finger artery
dilatation, reflecting greater nitric oxide-mediated vasodilation of these vessels and thus better
local EF. Validation studies indicate that the EndoPAT reliably captures finger EF, and reflects
the extent of nitric oxide-induced vasodilation in response to hyperemia (Bonetti et al., 2004;
Nohria et al., 2006). Mounting evidence suggests that the RHI generated by the EndoPAT can
identify the early stages of atherosclerosis (Bonetti et al., 2004) and predicts the occurrence of
adverse cardiovascular events (Rubinshtein et al., 2010). RHI also show high levels of
reproducibility when used with healthy children, adolescents, and adults (ICC = .78; Tierney et
al., 2009; Tomfohr et al., 2008).
Time (mont
SELF-ESTEEM VARIABILITY AND ARTERIAL STIFFNESS 2
Supplemental Table 1. Results of HLM model predicting changes in AI and RHI over time from
control variables only.
Intercept (Baseline)
Slope (Trajectory)
β
SE
p
β
SE
p
Ethnicity
0.55
0.18
< .01
1.5x10-3
9.7x10-3
.88
Age
4.0x10-2
8.2x10-2
.62
2.6x10-3
4.1x10-3
.53
SES
1.3x10-2
2.7x10-2
.63
4.9x10-4
1.3x10-3
.70
WHR
-1.8
1.6
.27
-2.4x10-2 8.2x10-2
.77
Variable
Arterial Stiffness (AI)
Endothelial Function (RHI)
Ethnicity
-6.5x10-2 0.18
.72
1.0x10-3
9.9x10-3
.31
Age
-6.0x10-2 6.8x10-2
.38
2.3x10-3
3.3x10-3
.48
SES
-1.0x10-3 2.5x10-2
.68
-1.5x10-3 1.2x10-3
.20
WHR
2.1
.22
-5.0x10-2 0.11
.66
1.8
SELF-ESTEEM VARIABILITY AND ARTERIAL STIFFNESS 3
Supplemental Table 2. Results of HLM model predicting changes in AI and RHI over time from
control variables, SEV, trait self-esteem, and self-esteem x SEV interaction.
Intercept (Baseline)
Slope (Trajectory)
β
SE
p
β
SE
p
Ethnicity
0.58
0.19
< .01
1.3x10-3
9.9x10-3
.89
Age
3.7x10-2
8.2x10-2
.65
3.0x10-3
4.1x10-3
.46
SES
1.5x10-2
2.8x10-2
.58
3.6x10-4
1.3x10-3
.79
WHR
-1.9
1.7
.26
-3.4x10-2 7.9x10-2
.67
Trait self-esteem
1.9x10-2
8.3x10-2
.82
1.8x10-3
3.6x10-3
.62
SEV
-3.0x10-2 8.6x10-2
.73
8.0x10-3
3.8x10-3
.04
Interaction
-5.9x10-2 8.5x10-2
.49
-4.0x10-3 4.0x10-3
.33
Ethnicity
-4.0x10-2 0.18
.82
8.5x10-3
1.0x10-2
.41
Age
-4.4x10-2 6.9x10-2
.53
1.8x10-3
3.2x10-3
.57
SES
-1.2x10-2 2.5x10-2
.64
-1.5x10-3 1.3x10-3
.26
WHR
2.0
1.7
.25
-4.7x10-2 0.11
.68
Trait self-esteem
7.3x10-2
8.1x10-2
.37
-3.2x10-3 4.3x10-3
.45
SEV
3.8x10-2
7.8x10-2
.63
3.1x10-3
4.1x10-3
.45
Interaction
6.7x10-2
8.3x10-2
.42
-4.1x10-3 4.1x10-3
.31
Variable
Arterial stiffness (AI)
Endothelial Function (RHI)
SELF-ESTEEM VARIABILITY AND ARTERIAL STIFFNESS 4
Supplemental Table 3. Results of HLM model predicting changes in AI and RHI over time from
control variables, SEV, trait self-esteem, and mood and health practices.
Variable
Arterial stiffness (AI) Intercept
Arterial stiffness (AI) Slope
(Baseline)
(Trajectory)
β
SE
p
β
SE
Ethnicity
0.46
0.20
.02
-1.7x10-3
1.1x10 -2 .88
Age
6.7x10-2
7.3x10-2
.36
2.7x10-3
4.3x10-3
.52
SES
1.2x10-2
3.2x10-2
.75
5.5x10-4
1.6x10-3
.73
WHR
-1.4
1.8
.44
-5.6x10-2
8.3x10-2
.50
Trait self-esteem
-7.2x10-2
0.16
.66
8.8x10-3
5.8x10-3
.13
SEV
-2.4x10-2
.12
.84
1.2x10-2
5.4x10-3
.03
Depressed Mood
9.7x10-3
3.8x10-2
.80
4.2x10-4
1.3x10-3
.75
Mood variability
-2.5x10-2
8.6x10-2
.77
6.9x10-4
1.3x10-3
.87
Ethnicity
4.9x10-2
0.20
.02
-6.7x10-3
1.1x10-2
.54
Age
7.1x10-2
7.4x10-2
.34
3.5x10-3
4.0x10-3
.39
SES
1.2x10-2
2.9x10-2
.67
-4.3x10-4
1.5x10-3
.78
WHR
-1.2
1.8
.49
-5.9x10-2
8.2x10-2
.47
Trait self-esteem
-2.2x10-2
9.4x10-2
.82
4.6x10-3
3.7x10-3
.22
SEV
-2.5x10-2
8.9x10-2
.78
1.2x10-2
5.0x10-3
.02
Alcohol consumption
5.4x10-3
1.9x10-2
.78
-1.7x10-3
1.3x10-3
.18
Ethnicity
0.51
0.20
.01
-2.1x10-3
1.0x10-2
.84
Age
8.5x10-2
7.9x10-2
.29
3.1x10-3
4.7x10-3
.50
SES
1.1x10-2
2.9x10-2
.71
-4.2x10-4
1.5x10-3
.79
p
SELF-ESTEEM VARIABILITY AND ARTERIAL STIFFNESS 5
WHR
-1.4
1.8
.44
-6.9x10-2
8.2x10-2
.40
Trait self-esteem
-2.6x10-2
9.4x10-2
.78
5.4x10-3
3.7x10-3
.15
SEV
-2.1x10-2
8.5x10-2
.81
1.2x10-2
5.0x10-3
.02
Physical activity
4.8x10-4
6.2x10-4
.45
5.0x10-6
4.2x10-5
.90