acetaminophen (Tylenol) Functional class: antipyretic, nonopioid analgesic Uses: mild to moderate pain/ fever Side Effects: anemia, rash, nausea, vomiting Contraindications: Assess: hepatic toxicity, allergic reaction, chronic poisoning albuterol Functional Class: bronchodilation, sympathomimetic, adrenergic b2agonist Uses: prevention of asthma, acute bronchospasm, bronchitis Side Effects: tremors, anxiety, restlessness, bronchospasm Contraindications: hypersensitivity to sympathominmetrics, tachydysrhythmias, severe cardiac disease, heart block. Assess: respiratory function, allergic reactions, bronchospasm alprazolam (Xanax) Functional class: anti – anxiety Uses: anxiety, panic disorders, depression Side Effects: dizziness, drowsiness, orthostatic hypotension, blurred vision, tachycardia Contraindications: pregnancy, breastfeeding, addiction Assess: mental status, hepatic blood studies, physical dependency amoxicillin (Amoxill) Functional Class: antiinfective, antiulcer Uses: skin, respiratory, GI, GU, ear infections Side Effects: nausea, vomiting, diarrhea, bone marrow depression Contraindications: hypersensitivity to penicillin Assess: teaching: report sore throat, fever, fatigue Benadryl Functional class: antihistamine Uses: allergy symptoms, rhinitis, motion sickness, nighttime sedation, infant colic, non-productive cough, insomnia in children Side Effects: Dizziness, Drowsiness, urinary retention, anemia, anaphylaxis Contraindications: hypersensitivity to H1-receptor antagonist, acute asthma attack, lower respiratory tract disease, neonates Assess: Respiratory status bisacodyl Functional Class: Laxative, stimulant Uses: short-term treatment of constipation, bowel or rectal prep. for surgery Side Effects: nausea, vomiting, diarrhea, anorexia, cramps, tetany Contraindications: hypersensitivity, rectal fissures, abdominal pain, nausea, vomiting, appendicitis, acute surgical absess, ulcerated hemorrhoids, acute hepatitis, fecal impaction Assess: buPROPion (Wellbutrin) Functional Class: antidepressant Uses: depression, smoking cessation, seasonal affective disorder Side Effects: Headaches, agitation, dizziness, seizures, insomnia, sedation Contraindications: hypersensitivity, eating disorders, seizure disorders Assess: hepatic/ renal function, mental status/ mood, seizure risk cefazolin sodium (Ancef) Functional Class: Anti-infective Uses: gram-negative bacilli Side Effects: seizures, renal failure, diarrhea, anorexia, dizziness, weakness Contraindications: hypersensitivity to chephalo sporins, infants < 1 month Assess: Nephrotoxicity, Anaphylaxis, overgrowth of infection ceftriaxone (Rocephin) Functional Class: Broad-spectrum antibiotic Uses: gram-negative bacilli, gram-positive organisms Side Effects: nausea, vomiting, diarrhea, anorexia, seizures, heart failure, bleeding Contraindications: hypersensitivity to cephalosporins, infants < 1 month Assess: nephrotoxicity, anaphylaxis, overgrowth of infection Teach: to report sore throat, bruising, bleeding, joint pain, diarrhea with mucus diazepam (Valium) Functional Class: antianxiety, anti-convulsant, skeletal muscle relaxant Uses: anxiety, acute alcohol withdrawal, adjunct in seizure disorders. Side Effects: dizziness, drowsiness, confusion, orthostatic hypotension, ECG changes Contraindications: pregnancy, hypersensitivity to benzodiazepines, closed-angle glaucoma, coma, myasthenia gravis, ethanol intoxication, hepatic disease, sleep apnea Assess: BP- sitting, lying, standing digoxin (Lanoxin) Functional Class: cardiac glycoside, inotropic, antidysrhythmic Uses: heart failure, atrial fibrillation, atrial flutter, atrial tachycardia, cardiogenic shock, paroxysmal atrial tachycardia, rapid digitalization Side Effects: headache, hypotension, dysrhythmias, drowsiness Contraindications: hypersensitivity to digoxin, ventricular fibrillation, ventricular tachycardia, carotid sinus syndrome, 2nd/ 3rd degree heart block Assess: Apical pulse for 1 min. before giving diltiazem Functional Class: calcium channel blocker, antiarrhythmic class IV, antihypertensive Uses: angina pectoris due to coronary artery spasm, hypertension, atrial fibrillation, flutter, paroxysmal supraventricular tachycardia Side Effects: headaches, fatigue, drowsiness, edema, dysrhythmias, CHF Contraindications: sick sinus syndrome, AV heart block, hypotension < 90 mmHg systolic, acute MI, pulmonary congestion, cardiogenic shock Assess: Teach: report dizziness, SOB, palpitations docusate sodium (Colace) Functional Class: laxative, emollient stool softener Uses: prevention of dry, hard stools Side Effects: bitter taste, throat irritation, nausea, anorexia, cramps, Rash Contraindications: hypersensitivity, obstruction, fecal impaction, nausea/vomiting Assess: cause of constipation enoxaparin (Lovenox) Functional Class: Anticoagulant, antithrombotic Uses: prevention of DVT, PE in hip and knee replacements Side Effects: fever, confusion, nausea, hemorrhage, bleeding Contraindications: hypersensitivity to this product, benzyl alcohol, heparin, or pork ** DO NOT INTERCHANGE WITH HEPARIN OR LMWHS epoetin (Epogen) Functional Class: anti-anemic, biologic modifier hormone Uses: anemia caused by reduced endogenous erythropoietin production Side Effects: seizures, HTN, coldness, sweating, CHF, DVT Contraindications: hypersensitivity to mammalian cell Assess: blood studies, PRCA famotidine (Pepcid) Functional Class: H2- histamine receptor antagonist Uses: short-term treatment of active duodenal ulcer, maintenance therapy for duodenal ulcers Side Effects: headache, dizziness, paresthesia, seizures, dysrhythmias, seizures, constipation Contraindications: hypersensitivity Assess: blood counts fentanyl transdermal (Duragesic) Functional Class: opioid analgesic Uses: controls moderate to severe pain, adjunct to general anesthesia (conscious sedation) Side Effects: dizziness, delirium, euphoria, bradycardia Contraindications: hypersensitivity to opiates, myasthenia gravis ** Black Box Warning: children. accidental exposure, ambient temperature increase, fever, opioid-naïve patients, skin abrasion, substance abuse, respiratory depression furosemide (Lasix) Functional Class: Loop Diuretic Uses: pulmonary edema, edema in CHF, hepatic disease, nephrotic syndrome, ascites, HTN Side Effects: hypokalemia, hypochloremic alkalosis, hypomagnesemai, hypocalcemia, hyperglycemia, renal failure, circulatory collapse Contraindications: breastfeeding, infants, hypersensitivity to sulfonamides, anuria, hypovolemia, electrolyte depletion gentamicin (Garamycin) Functional Class: Anitinfective Uses: severe systemic infections of CNS, UTI, bone, skin Side Effects: deafness, nausea, vomiting, anorexia, seizures, neurotoxicity Contraindications: hypersensitivity to this or other aminoglycosides, fungal/viral/mycobacterial infection ** BLACK BOX WARNING: pregnancy, severe renal disease, mild renal disease, hearing deficits, myasthenia gravis, Parkinson’s disease glipizide (Glucotrol) Functional Class: Antidiabetic Uses: Type 2 Diabetes Mellitus Side Effects: headache, weakness, dizziness, drowsiness, hypoglycemia Contraindications: hypersensitivity to sulforylureas, type 1 diabetes, diabetic ketoacidosis Assess: Hypo/hyperglycemic reaction that can occur soon after meals, CBC baseline/ throughout treatment glyBURIDE Functional Class: Antidiabetic Uses: Type 2 Diabetes Side Effects: Headache, weakness, hypoglycemia, nausea Contraindications: hypersensitivity to sulfonylureas, type 1 diabetes, diabetic ketoacidosis, renal failure haloperidol (Haldol) Functional Class: Antipsychotic, neuroleptic Uses: psychotic disorders, control of tics, short term treatment of hyperactive children showing excessive motor activity Side Effects: drowsiness, headaches, orthostatic hypotension, nausea, vomiting, seizures Contraindications: children < 3 years, hypersensitivity, coma, brain damage, bone marrow depression, alcohol and barbiturate withdrawal, Parkinson’s Disease, angina, epilepsy, urinary retention, closed-angle glaucoma Assess: neuroleptic malignant syndrome, hyperthermia, muscle rigidity, altered mental status, increased CPK, hyper/hypotension, tachycardia heparin (Hep-lock) Functional Class: Anticoagulant, antithrombotic Uses: prevention of DVTs, PE, MI, open heart surgery, disseminated intravascular clotting syndrome, atrial fibrillation with embolization, as an anticoagulant in transfusion and dialysis procedures, to maintain patency of IV’s Side Effects: fever, rash, chills, hematuria, hemorrhage Contraindications: hypersensitivity, hemophilia, leukemia, peptic ulcer disease, severe renal/hepatic disease, severe HTN, subacute bacterial endocarditis, nephritis Assess: bleeding gums, petechiae, ecchymosis, black tarry stools, hematuria, epistaxis, decrease in Hct, BP hydrochlorothiazide (Esidrix) Functional Class: Thiazide diuretic, anti-hypertensive Uses: edema, hypertension, diuresis, CHF, estrogen, NSAIDS, idiopathic lower extremity edema Side Effects: dizziness, fatigue, weakness, glucosuria Contraindications: hydrocodone ASA Functional Class: antitussive opioid analgesic/ nonopioid analgesic Uses: hyperactive and nonproductive cough, mild-moderate pain Side Effects: drowsiness, nausea, vomiting, anorexia, constipation, respiratory depression Contraindications: acne rosacea/ vulgaris, Cushing’s, measles, perioral dermatitis, varicella, abrupt discontinuation, hypersensitivity to this product, or benzyl hypersensitivity Assess: pain, CNS changes, allergic reactions hydromorphone (Dilaudid) Functional Class: opiate analgesic Uses: moderate to severe pain, non-productive cough Side Effects: drowsiness, dizziness, confusion, sedation, seizures, respiratory depression Contraindications: hypersensitivity Assess: respiratory depression, allergic reactions, pain control ** BLACK BOX WARNING: respiratory depression, opioid-naïve patients, substance abuse ibuprofen (Advil, Motrin) Functional Class: NSAID, antipyretic nonopioid analgesic Uses: Rheumatiod arthritis, osteoarthritis, primary dysmenorrhea, gout, dental pain, musculoskeletal disorders, fever, migraine Side Effects: headache, anorexia, vomiting, diarrhea, MI, Stroke Contraindications: pregnancy 3rd trimester, hypersensitivity, asthma, severe renal/hepatic disease Assess: renal, pain, audiometric, ophthalmic, infection, cardiac ** BLACK BOX WARNING: Perioperative pain in CABG, GI bleeding, MI, Stroke Insulins (Novolog, Humulin, Regular, Lantus, Levemir, Apidra) Functional Class: anti-diabetic, pancreatic hormone Uses: type 1 & 2 diabetes, gestational diabetes, insulin lispro may be used in combination with sulfonylureas in children > 3 yr. Side Effects: lipodystrophy, hypoglycemia, peripheral edema, anaphhlaxis Contraindications: hypersensitivity to protamine, creosol Assess: fasting blood glucose, A1c too identify effectiveness of treatment, urine ketones during illness ketorolac (Toradol) Functional Class: NSAID/ nonopioid analgesic Uses: mild to moderate pain, seasonal allergic conjunctivitis Side Effects: drowsiness, seizures, HTN, cramps, dry mouth Contraindications: pregnancy 3rd trimester, hypersensitivity, asthma, hepatic disease, peptic ulcer, CV bleeding Assess: hepatic dysfunction: jaundice, yellow sclera and skin, clay-colored stools, for CV thrombotic events: MI, stroke ** BLACK BOX WARNING: breastfeeding, renal disease, L&D, perioperative pain in CABG, prior to major surgery, epidural/intrathecal administration, GI bleeding, hypovolemia, children, geriatric patients, bleeding, MI, stroke levothyroxine (T4) Functional Class: Thyroid Hormone Uses: hypothyroidism, myxedema, coma, thyroid hormone, replacement, thyrotoxicosis, congenital hypothyroidism, some types of thyroid cancer, pituitary TSH suppression Side Effects: anxiety, insomnia, tremors, tachycardia, cardiac arrest Contraindications: adrenal insufficiency, recent MI, thyrotoxicosis, hypersensitivity to beef, alcohol intolerance Assess: BP, weight, bleeding, bruising, cardiac ** BLACK BOX WARNING: obesity treatment lisinopril (Prinivil) Functional Class: antihypertensive, ACE inhibitor Uses: mild to moderate hypertension, adjunctive therapy of systolic CHF, acute MI Side Effects: vertigo, fatigue, stroke, diarrhea Contraindications: hypersensitivity, angioedema Assess: blood studies, platelets; WBC with differential baseline and periodically q3 mo. ** BLACK BOX WARNING: pregnancy lorazepam (Ativan) Functional Class: sedative, hypnotic, antianxiety Uses: anxiety, irritability in psychiatric or organic disorders, preoperatively, insomnia, adjunct in endoscopic procedures Side Effects: dizziness, drowsiness, orthostatic hypotension, apnea, cardiac arrest Contraindications: pregnancy, breast feeding, hypersensitivity to benzodiazepine, benzyl alcohol, sleep apnea, closed-angle glaucoma, psychosis, history of drug abuse, COPD Assess: suicidal tendencies metoprolol (Toprol XL) Functional Class: Antihypertensive, anti-anginal Uses: mild to moderate hypertension, acute MI to reduce cardiovascular mortality, angina pectoris, NVHA class II, III, heart failure Side Effects: insomnia, dizziness, palpitations, nausea, vomiting, diarrhea, hiccups, chest pain, peripheral edema Contraindications: hypersensitivity to b-blockers, cardiogenic shock, heart block (2nd, 3rd degree), sinus bradycardia, pheochromocytoma, sick sinus syndrome Assess: apical pulse before administration ** BLACK BOX WARNING: abrupt discontinuation metronidazole (Flagyl) Functional Class: anti-infective, miscellaneous Uses: intestinal amebiasis, amebic abscess, trichomoniasis, refractory trichomoniasis, bacterial anaerobic infections, giardiasis, septicemia, endocarditis, bone, joint infections, lower respiratory tract infections, rosacea Side Effects: headaches, dizziness, seizures, nausea, vomiting, diarrhea Contraindications: pregnancy 1st trimester, breast feeding hypersensitivity to this product, GI/ renal/hepatic disease, contracted visual/ color fields, CNS disorders Assess: neurotoxicity **BLACK BOX WARNING: secondary malignancy Morphine Sulfate Functional Class: opioid analgesic Uses: moderate to severe pain Side Effects: drowsiness, dizziness, confusion, seizures, bradycardia Contraindications: hypersensitivity, addiction, hemorrhage, bronchial asthma, increased intracranial pressure Assess: pain, bowels, I&O, BP, P, Respirations, CNS changes, allergy , respiratory depression ** BLACK BOX WARNING: respiratory depression, abrupt discontinuation, accidental exposure, epidural/intrathecal administration, opioid-naïve patients, substance abuse nalbuphine (Nubain) Functional Class: opioid analgesic Uses: moderate to severe pain Side Effects: drowsiness, dizziness, confusion, nausea, vomiting, constipation, cardiac arrest Contraindications: hypersensitivity, addiction Assess: withdrawal reactions, PE, vascular occlusion, abscesses, ulcerations, nausea, vomiting, seizures. omeprazole (Prilosec) Functional Class: antiulcer, proton pump inhibitor Uses: GERD, esophagitis, systematic mastocytosis Side Effects: headaches, dizziness, asthenia, heart failure Contraindications: hypersensitivity Assess: GI system, hepatic enzymes ondansetron (Zofran) Functional Class: antiemetic Uses: nausea, vomiting Side Effects: headache, dizziness, drowsiness, fatigue, diarrhea, constipation, bronchospasm Contraindications: hypersensitivity Assess: hypersensitivity reaction, rash, bronchospasm naloxone (Narcan) Functional Class: opioid antagonist, antidote Uses: respiratory depression induced by opioids, pentazocine, propoxyphene, refractory circulatory shock, asphyxia neonatorum, coma, hypotension Side Effects: drowsy, nervous, seizures, rapid pulse Contraindications: hypersensitivity Assess: withdrawal, respiratory dysfunction, pain pantoprazole (Protonix) Functional Class: proton pump inhibitor Uses: GERD, esophagitis, maintenance Side Effects: headache, diarrhea, abdominal pain, rash, pneumonia Contraindications: hypersensitivity Assess: GI, hepatic studies oxycodone (Percocet) Functional Class: opiate analgesic Uses: moderate to severe pain Side Effects: drowsiness, dizziness, confusion, headache, nausea, vomiting, respiratory depression Contraindications: hypersensitivity, addiction, asthma, ileus Assess: I&O, CNS, allergy, respiratory depression, pain **BLACK BOX WARNING: respiratory depression, opioid piperacillin, tazobactam (Zosyn) Functional Class: broad spectrum anti-infective Uses: moderated to severe infections Side Effects: nausea, vomiting, diarrhea, renal failure Contraindications: hypersensitivity to penicillin, neonates, carbapenem allergy Assess: compromised renal system, toxicity potassium Cl Functional Class: electrolyte, mineral replacement Uses: prevention / treatment of hypokalemia Side Effects: nausea, vomiting, diarrhea, cramps, cardiac depression Contraindications: renal disease, hemolytic disease, Addison’s, hyperkalemia, dehydration, tissue breakdown Assess: ECG, K+ levels, I&O, cardiac status prednisone (PredniSONE) Functional Class: Corticosteroid Uses: severe inflammation, immune suppression, neoplasms, MS, collagen disorders, dermatologic disorders Side Effects: depression, flushing, mood changes, circulatory collapse Contraindications: child < 2 yr. , psychosis, hypersensitivity, AIDs, idiopathic thrombocytopenia, glomerulonephritis, amebiasis, fungal infection, TB, measles Assess: ** DO NOT DISCONTINUE ABRUPTLY, MAY CAUSE ADRENAL CRISIS promethazine (Phenergan) Functional Class: antihistamine, H1-receptor antagonist Uses: motion sickness, rhinitis, allergy symptoms, sedation, nausea, preoperative/ postoperative sedation Side Effects: Dizziness, drowsiness, constipation, urinary retention, neuroleptic malignant syndrome Contraindications: hypersensitivity, breast feeding, agranulocytosis, bone marrow suppression, coma, jaundice, Reye’s syndrome Assess: CBC **BLACK BOX WARNING: infants, neonates, children, intra-arterial administration, SUBCT administration, IV use sertraline (Zoloft) Functional Class: Anti-depressant Uses: Major depressive disorder, OCD, PTSD, panic disorders, social anxiety, PMDD Side Effects: insomnia, agitation, dizziness, fatigue, seizures Contraindications: Hypersensitivity to this product and SSRIs Assess: mental status, BP, urinary retention spironolactone (Aldactone) Functional Class: Potassium-sparing diuretic Uses: edema of CHF, HTN, diuretic induced hypokalemia cirrhosis of liver with ascites Side Effects: headache, diarrhea, vomiting, hyperkalemia, bleeding Contraindications: pregnancy, hypersensitivity, anuria, severe renal disease, hyperkalemia Assess: Electrolytes, weight, I&O **BLACK BOX WARNING: Secondary malignancy transdermal (Transderm-Nitro) Functional Class: coronary vasodilator, antianginal Uses: chronic stable angina pectoris, prophylaxis of angina pain, CHF associated with acute MI, controlled hypotension in surgical procedures Side Effects: headache, flushing, dizziness, postural hypotension, collapse Contraindications: Hypersensitivity to this product or nitrites, severe anemia, increased intracranial pressure, cerebral hemorrhage, closedangle glaucoma, cardiac tamponade, cardiomyopathy, constrictive pericarditis Assess: pain, orthostatic BP, tolerance, headache warfarin (Coumadin) Functional Class: anticoagulant Uses: antiphospholipid antibody syndrome, arterial thromboembolism prophylaxis, DVT, MI, prophylaxis, post MI, stroke prophylaxis Side Effects: fever, diarrhea, rash, hematuria Contraindications: pregnancy, breastfeeding, hypersens, hemophilia, ulcers, bleeding, eclampsia, CNS surgery, etc. Assess: blood studies, INR, bleeding gums, petechiae, hematuria, fever, rash, urticarial **BLACK BOX WARNING: bleeding azithromycin (Zithromax) Functional Class: Antiinfective Uses: Mild to moderate infections of the respiratory tract, and uncomplicated skin infections. Side Effects: Nausea, vomiting, diarrhea, hepatotoxicity, jaundice Contraindications: Hypersensitivity to macrolides Assess: I&O, hepatic/ renal studies, super-infections. Teach: report sore throat, fever, fatigue, severe diarrhea, or genital itching (May indicate super-infection). Also report severe abdominal pain, dark urine, or yellow discoloration of eyes and skin. influenza virus vaccine Trade names: Afluria, FluMist, Fluogen, Flu-Shield, Fluvirin, Fluzone, trivalent Uses: Prevention of Russian, Chilean, or Philippian influenza Route: IM Contraindications: Hypersensitivity, active infection, chicken egg allergy, active neurologic disorders Tetanus (Dt) diphtheria and tetanus toxoids, adsorbed Uses: Induces antitoxoids to provide immunity to diphtheria and tetanus Route: IM Contraindications: Hypersensitivity to mercury, thimerosal, immunocompromised patients, radiation, corticosteroids, and acute illness