DNA Replication Project DNA is essential to all life. DNA allows for genetic information to be stored, copied and transmitted from one cell to the next. Right now you cells are copying their DNA. And, the DNA that is being copied in your skin cells is identical to the DNA being copied in your liver cell (and every cell inside of your body). In order to understand the process of replication, and how it differs from prokaryotic cell DNA replication, you will complete a DNA replication project. First, you must choose a product. Choose carefully because you will need to demonstrate your knowledge of the difference between prokaryotic and eukaryotic DNA replication; the steps of eukaryotic DNA replication (leading, lagging strand and Okazaki fragments); and knowledge of eukaryotic DNA replication enzymes (Helicase, Ligase, and DNA polymerase). Second, if you are working with a partner you MUST present your project to your classmates. If you are working alone you may present for EXTRA CREDIT. Finally, if you have a product in mind that is not listed below, please ask. Odds are that you will be able to have your project approved, provided that you can demonstrate all the information required. In addition, the most creative and original project will be rewarded with extra credit. PRODUCTS - Comic Strip - Pop Song/Rap - Children’s Story - Hand Drawn Poster Illustration with Descriptions - PowerPoint Presentation - Movie - 3-D Model with Descriptions - Analogy Poster with Descriptions Content / Structure 15 points Beginning Missing some major components of DNA structure Developing Most structural components are labeled in detail, some components are missing Accomplished Most structural components are labeled in detail, only a few minor components are not labeled Exemplary All structural components are addressed in detail DNA double helix, nucleotides, deoxyribose, nitrogen bases (Adenine, Thymine, Guanine, Cytosine) phosphate, 5 and 3 prime, antiparallel, DNA ligase, DNA polymerase, helicase, replication fork, leading strand, lagging strand, Okazaki fragments, hydrogen bonding, covalent bonding, complementary base pairing, Prokaryotic DNA Replication. Content/ Process Missing some major processes Missing some minor processes 10 points Some minor errors to accuracy Entire process is correct and accurate Unzipping, unwinding, breaking hydrogen bonds, 5 to 3 prime direction of replication, complementary base pairing, joining of Okazaki fragments with ligase. Clarity 10 points Creativity 10 points Although an attempt is made, it is difficult to understand most of the project. Messy and/or Disorganized Most sections are well organized with clear identification, but some sections are not. Entire project is well organized, but a few of the parts/processes are not easily identifiable. Clear, concise vocabulary used; all parts/processes are clearly addressed. Project demonstrates no attempt at creativity. Project somewhat uses creativity for effect and purpose. Project uses creative effects, but somewhat distracts from overall understanding. Project aids understanding through creativity to enhance understanding. Total = _________/ 45 DUE DATE = _____________ Project Examples http://www.youtube.com/watch?v=m-ibk7zVyWI http://www.youtube.com/watch?v=iD5qDUZ6Sf0 Content / Structure 15 points Beginning Missing some major components of DNA structure Developing Most structural components are labeled in detail, some components are missing Accomplished Most structural components are labeled in detail, only a few minor components are not labeled Exemplary All structural components are addressed in detail DNA double helix, nucleotides, deoxyribose, nitrogen bases (Adenine, Thymine, Guanine, Cytosine) phosphate, 5 and 3 prime, antiparallel, DNA ligase, DNA polymerase, helicase, replication fork, leading strand, lagging strand, Okazaki fragments, hydrogen bonding, covalent bonding, complementary base pairing, Prokaryotic DNA Replication. Content/ Process Missing some major processes Missing some minor processes 10 points Some minor errors to accuracy Entire process is correct and accurate Unzipping, unwinding, breaking hydrogen bonds, 5 to 3 prime direction of replication, complementary base pairing, joining of Okazaki fragments with ligase. Clarity 10 points Creativity 10 points Although an attempt is made, it is difficult to understand most of the project. Messy and/or Disorganized Most sections are well organized with clear identification, but some sections are not. Entire project is well organized, but a few of the parts/processes are not easily identifiable. Clear, concise vocabulary used; all parts/processes are clearly addressed. Project demonstrates no attempt at creativity. Project somewhat uses creativity for effect and purpose. Project uses creative effects, but somewhat distracts from overall understanding. Project aids understanding through creativity to enhance understanding.