Center for Biological Sequence Analysis 13 positions in bioinformatics/systems biology at the Center for Biological Sequence Analysis, DTU The Center for Biological Sequence Analysis at the Technical University of Denmark was formed in 1993, and conducts basic research in the fields of bioinformatics and systems biology. The center is divided into ten specialist research groups, has a highly multi-disciplinary profile (biologists, biochemists, MDs, physicists, statisticians, and computer scientists) with a ratio of 2:1 of bio-to-nonbio backgrounds. CBS represents one of the large bioinformatics groups in academia in Europe. The successful candidates will be working within one of the following areas: Metagenomics group 3 PhD/postdocs in next gen sequencing related metagenomics The Metagenomics group is seeking highly motivated candidates for three PhD/postdoctoral positions. The project will have a special focus on implementing a new gene discovery pipe line for high-throughput sequencing data, bacterial assembly and next generation sequence analysis tools in a distributed computing environment. - Candidates applying for a PhD scholarship should hold a master’s degree in bioinformatics, biology, biochemistry, engineering, computer science or similar. - Postdoc candidates should hold a PhD degree in bioinformatics, biology, microbial ecology, engineering, computer science or similar. - The candidate must have strong computational skills and prior experience with Unix/Linux command line environments, SQL, as well as either Perl, Python, Ruby or a comparable scripting language. - The applicant must have prior experience with next generation sequencing data analysis and gene discovery. - Knowledge of genome assembly and large-scale data mining is considered a plus. - Knowledge of taxonomic classification and/or super trees is considered a plus. - The applicant must be a good communicator and strong in written as well as spoken English. Contact: Associate professor, group leader Thomas Sicheritz-Pontén, tel.: +45 4525 2422 or +46 706572471 1 postdoc position in archaeal genetics The successful candidate will be based at the University of Helsinki, part of the work will be carried out at the Technical University of Denmark. The project will focus on the analysis of fungus associated archaea in boreal forest soils by next generation sequencing as well as stable isotope metabolic experiments. - Candidates applying for the postdoctoral position should have a PhD degree in the field of microbial ecology or genetics. - The applicant should have a strong publication record and the ability to work independently. - Experience in next generation sequence analysis, gene annotation and stable isotope techniques is an advantage. Contact: Associate professor, group leader Thomas Sicheritz-Pontén, tel.: +45 4525 2422 or +46 706572471 Immunological bioinformatics group The Immunological bioinformatics group is seeking highly motivated candidates for a postdoc position as well as a scientific programmer position. The group is involved in establishing a new center for global molecular epidemiology focusing on the pathogenicity and systems biology of bacteria. 1 postdoc within predictive bioinformatics for molecular epidemiology - The candidate will work on the development of pathogenicity prediction tools for a wide range of bacteria. - The candidate will help coordinate the project which involves partners at DTU Food as well as collaborators in the US. 1 scientific programmer for molecular epidemiology - The work involves programming novel genome typing applications. - The candidate will work closely together with other scientific staff members from IT, epidemiology and immunological bioinformatics. Contact: Professor, group leader Ole Lund, tel.: +45 4525 2425 1 PhD within epitope prediction - Development of tools for epitope prediction including tools with pan-specific MHC allelic coverage, and structural B cell epitope identification. Contact: Associate professor Morten Nielsen, tel.: +45 4525 2425 Functional human variation group A PhD position is available in collaboration with the COPSAC group at the Copenhagen University Hospital, to study gene-environment interactions leading to childhood asthma. There is a strong emphasis on data integration incorporating genome wide association studies, protein-protein interactions, disease functional networks and patient text mining. 1 PhD within childhood asthma systems biology - Candidates are expected to have prior computational or human genetics background, preferably both. - The ideal PhD candidates should hold an MD, a Master of Science degree, or the equivalent in bioinformatics, computer science, genetics or cellular biology. - For well experienced candidates with a strong PhD, a postdoc position may be considered. Contact: Associate professor, group leader Ramneek Gupta, tel.: +45 4525 2422 Integrative systems biology group We seek PhD/postdoc candidates for projects within disease systems biology with focus on overlapping pathways and shared genes between diseases. The projects typically involve data integration of highly diverse data types, from the molecular level to phenotypic data from electronic patient records and biobank questionnaires. 1 PhD within disease systems biology - The ideal PhD candidates should hold an MD, a Master of Science degree, or the equivalent in bioinformatics, computer science, or cellular biology. - Experience with biological data analysis or text mining would be favorable along with good analytical skills. 1 postdoc within disease systems biology - The ideal postdoc should have a PhD degree in the field of bioinformatics, computer science, or cellular biology. - Experience with biological data analysis or text mining would be favorable along with good analytical skills. 1 scientific programmer within disease systems biology - The ideal scientific programmer should have sound object-oriented language knowledge. - Preferably with JAVA or C++, experience with Perl, SQL, UNIX, php, html, and experience from other biological computing projects. Contact: Professor, center director and group leader Søren Brunak, tel.: +45 4525 2477 Regulatory genomics group The Regulatory genomics group is seeking highly motivated candidates for a PhD or postdoc position (3 years). The research project would focus on topics related to the informatics of non-coding RNA genes as part of the newly established center for noncoding RNA in technology and health which includes a collaboration with the University of Copenhagen. 1 PhD/postdoc in non-coding RNA genomics - PhD candidates must have a Masters degree in bioinformatics, molecular biology or related fields. Postdoctoral candidates must have a PhD in one of these areas. - Computational skills, data analysis, applied statistics, and a fundamental understanding of biology OR molecular biology skills related to RNA - isolation, DNA microarray or high-throughput sequencing along with basic informatics skills. Ideal candidates will have analysis experience with high-throughput sequencing data and analysis of miRNA or siRNA data. Contact: Associate professor, group leader Christopher Workman, tel.: +45 4525 6148 DTU multi-assay core facility We seek a data analyst or bioinformatician with experience with data from microarrays, next generation sequencing, flow-cytometry or cellular assays. 1 postdoc or research assistant, bioinformatics generalist It is essential that the applicant has data analysis and statistics experience, computational skills and a fundamental understanding of biology. Experience with scripting languages, bioinformatics packages (Python/biopython, R/bioconductor, or others) is required, and knowledge of compiled languages (C, C++, Java) or web development is considered a plus. Contact: Senior researcher, head of core facility Laurent Gautier, tel.: +45 4525 6145 General information for PhD positions: Approval and enrolment The scholarships for the PhD degree are subject to academic approval, and the candidates will be enrolled in one of the general degree programmes of DTU. For information about the general requirements for enrolment and the general planning of the scholarship studies, please see the DTU PhD Guide. Salary and appointment terms The salary and appointment terms are consistent with the current rules for PhD degree students. A PhD study in Denmark is three years in duration. For postdoc and scientific programmer positions: Salary and terms of employment The appointment will be based on the collective agreement with the Confederation of Professional Associations. The allowance will be agreed with the relevant union. Further information: Further information may be obtained from center administrator Dorthe Kjærsgaard, tel.: +45 4525 2480. Application We must have your online application by 1 March 2010. Please open the link "apply for this job online" and fill in the application form and attach your application and CV including reference contacts. All interested candidates irrespective of age, gender, race, religion or ethnic background are requested to apply.