Lead Investigator First Hansel Name Lead Investigator J Middle Initial Lead Investigator Last Otero Name Lead Investigator MD Degree Institution Children's National Medical Center Current Institution Department of Diagnostic Imaging and Radiology Department Rank or Position Assistant Professor of Pediatric and Radiology Address 111 Michigan ave depart of radiology Washington, DC 20010 United States Phone Number (202) 476-4252 Fax (202) 476-3644 Training Dates • Brigham & Women’s Hospital – Harvard Medical School Jul 2005-Jun 2006 Gill Management and Hospital Administration Fellowship • Brigham & Women’s Hospital – Harvard Medical School Jul 2006- Jun 2007 Radiology Management Fellowship • Hurley Medical Center, Michigan State University Jul 2008- Jun 2009 Internship-Transitional year • Tufts Medical Center, Tufts University Medical School Jul 2009- Jun 2013 Diagnostic Radiology Residency • Children’s Hospital of Philadelphia Jul 2013- Jun 2014 Pediatric Radiology Fellowship Email hotero@childrensnational.org Upload Cover Letter spr2015coverletter1.doc 23.50 KB · DOC Is this application No based on an application submitted to this or any other organization in the past two years? Co- Lauren Investigator/Mentor First Name 1 Co- A Investigator/Applicant Name MI 1 CoInvestigator/Applicant Last Name 1 Crowder Co- BS, MPH, CPH Investigator/Applicant Degree 1 Co- Children's National Medical Center Investigator/Applicant 1 Institution Co- Co-investigator, public health/epidemiology expert Investigator/Applicant 1 Project Role Co- LCrowder@childrensnational.org Investigator/Applicant Name Email 1 Project Title Imaging Utilization in the Diagnosis of Appendicitis in Children in the United States: Analysis of trends, costs and outcomes Abstract of Proposed Research Plan (300 words) Appendicitis the most common surgical emergency in children in this country. Imaging has shown to decrease the rate of false positive cases without increasing complications. The recommendation for imaging suspected appendicitis in children according to ACR appropriateness criteria favors initial evaluation with ultrasound, with CT being useful after negative or equivocal ultrasound. Review of a large database suggested a decreased use of CT up to 2009 at major pediatric institutions, in keeping with acceptance of the benefits of initial investigation with US. However, a recent review of the same database of major pediatric hospitals shows a 3.5 folds difference in utilization rates of ultrasound and CT. Variation might be even higher in non-pediatric hospitals, which manage up to 80% of appendicitis cases in the country. To date it is unclear if the variation is related to type of institution or type of patient (i.e. demographics). Moreover, t hese findings might be used as a corollary for measuring impact of increased public awareness about the potential harmful effects of ionizing radiation, driven in part by a national education and communication campaign in radiology, Image Gently(SM), on clinical practice. In the last few years, alternative imaging algorithms to limit the use of CT that include repeat ultrasounds and the incorporation of MRI, have been proposed. The adoption and financial impact of these alternative pathways are also unknown. We propose to determine the trends and variation of imaging utilization practices in the US over the last 12 years and their relationship to demographic and outcomes. The cost fraction represented by imaging in pediatric appendicitis expenses will also be established. If decrease CT and increased ultrasound and/or MRI utilization can be achieved without increasing cost or negatively impacting outcomes, then a recommendation to update the ACR guidelines can be made. Upload: Detailed plan and bibliography appy_spr_seed_grant_31015.docx 42.15 KB · DOCX Resources and Environment: The PI has prior relevant training including 2 years of dedicated research fellowships on radiology administration and hospital management as well as over 15 publications in health services topics16171819. Specifically, he has prior publications studying imaging utilization trends on common diseases using a single institution data2021. More recently, he received dedicated training on the use and mining of the Pediatric Health Information System (PHIS) database. There is dedicated office space and protected research time to devote to this project. The database and statistical packages for use in analyses of this project will be housed on a department PC. All members of the research team work closely together both in intellectual capacity and physical proximity within the hospital, making collaboration on research very convenient. This research will take place within the Department of Diagnostic Imaging and Radiology within Children’s National Health System. The Department of Diagnostic Imaging and Radiology has received the ACR Gold Seal of Accreditation in Magnetic Resonance Imaging, Ultrasound, Computed Tomography, and Nuclear Medicine. The Department houses physicians, board certified pediatric radiologists, technologists, pediatric anesthesiologists, nurses, and numerous research faculty and staff. Additional Available resources in the hospital include statistical software licenses (SAS and Information: STATA), access to the PHIS database, biostatisticians familiar with large health claims dataset analysis, epidemiologists and public health experts, and the Child Health Advocacy Institute’s Child Health Data Lab, which is a major player in driving advocacy priorities in the Washington, DC metropolitan area. Fiscal Children’s National Health Systems Agent/Institution Award Payee First Hansel Name Award Payee Middle J Initial Award Payee Last Otero Name Award Payee Title Director Body MRI services Checks payable to: Hansel J Otero Award Payee Address 111 Michigan Ave Washington, DC 20010 United States Award Payee Phone (202) 476-4252 Number Award Payee Email hotero@childrensnational.org Grant Administrator's Charles First Name Grant Administrator's Maris Last Name Grant Administrator's Director, Grants and Contracts Title Grant Administrator's Department Grant Administrator's Children’s Research Institute Address 801 Roeder Rd., Suite 500 Silver Spring, MD 20910 United States Grant Administrator's (301) 565-8483 Phone Number Grant Administrator's cmaris@childrensnational.org Email Upload Budget otero_seed_budget.docx 13.97 KB · DOCX Upload Curriculum Vitae otero_seed_cv_2015.doc 76.00 KB · DOC (Upload) Mentor/CoInvestigators otero_coinvestigator_crowder_cv.docx 19.81 KB · DOCX