LIFE SCIENCE 12/13 Course A ESSENTIAL UNIT 3 (E03) (Genetics and Heredity) (June 2011) Unit Statement: In this unit the student will begin exploring the process of cell division (mitosis), study the experiments of Gregor Mendel and learn how genes and alleles interact to produce traits. The student will use probability to predict the outcome of specific genetic crosses. The student will draw connections between the chemical basis of inheritance (chromosomes and DNA) and observable patterns of inheritance. The student will apply the principles of genetics to human inheritance. Essential Outcomes: 1. The Student Will describe the results of Mendel’s experiments and explain the importance of their contribution to the study of genetics. (3.1) 2. TSW identify the role of alleles in controlling the appearance and inheritance of traits. (3.1) 3. TSW use Punnett squares to demonstrate the relationship between genotypes and phenotypes. (3.2) 4. TSW describe four complex patterns of inheritance. (3.3) 5. TSW discuss how characteristics result from a combination of genetics and environmental factors. (3.3) 6. TSW describe the relationship between DNA, genes and chromosomes and their roles in inheritance. (3.4) 7. TSW illustrate and relate the events that occur during meiosis, comparing and contrasting meiosis with mitosis. (3.4) 8. TSW describe the structure of proteins and explain the role of different types of RNA in making proteins. (4.2) 9. TSW explain how human traits are controlled in different ways resulting in different phenotypic expressions. (5.1) 10. TSW explain how genetic disorders are inherited in humans and how they are traced, diagnosed and treated. (5.2) 11. TSW apply the process of scientific inquiry with a focus on asking questions and creating hypotheses about genetics and inheritance. 13 QSI 12/13 LIFE SCI E03 Copyright © 1988-2011 Introduced and Practiced: 1. The Student Will describe the structure of DNA and explain how DNA is copied. (4.1) 2. TSW state the functions of the sex chromosomes and explain their role in inheritance of traits. (5.1) 3. TSW state the types of mutations that can form and how they can affect the organism. (4.3) 4. TSW describe the symptoms and causes of at least two disorders and explain how they are diagnosed and treated. (4.3, 5.1, 5.2) Key Terms: purebred hybrid dominant recessive trait heredity genetics gene allele phenotype genotype homozygous heterozygous codominance SUGGESTED RESOURCES & RUBRIC FOUND ON FOLLOWING PAGES........................ 14 QSI 12/13 LIFE SCI E03 Copyright © 1988-2011 Suggested Materials: Pearson Cells and Heredity, chapters 3, 4 and 5.1, 5.2 Ancillary materials are listed in the Course Outcome Statement Suggested Resources: 1. Students complete “Planet Diary” 2. In-text section reviews and enrichment 3. Pearson published activities: “Scenario-based Investigations,” “Interdisciplinary Activities,” “Chapter Activities,” “Inquiry Skill Activities, “Reading Strategies” for English Language Learners,” and “Math Skill and Problems-Solving Handbook.” 4. Students interested in further investigation may explore topics in cancer (p. 128), Advances in Genetics (5.3) or Genetic Information (5.4), roles of genetic disorders in history such as hemophilia in the Romanov royal family in Russia. Technology Resources: 1. 2. 3. 4. 5. Destiny Webpath Express (found on school’s automated library system) View “Untamed Science” videos. Students perform activities in “Interactive Art” and “Virtual Lab” Simulations: http://phet.colorade.edu Visuals, virtuals and animations: www.myscienceonline.com Suggested Assessment Tools and Strategies: 1. Create an illustrated dictionary of genetic terms. (TSW’s 1-14) 2. Students make a flipbook or animated video showing stages of meiosis. (TSW 8) 3. Students make a poster or chart, write a report or give a class presentation on any aspect of this unit (TSW’s 1-14) 4. Students research a particular genetic disorder, its cause, effects and treatments. (TSW 14) 5. Choose from Lab Zone® hands-on inquiries (see list of 29 related inquiries of varying length and difficulty in teacher’s edition, pT8-10 (TSW’s 1-14) 6. Students complete questions and activities in spaces provided in the text. (TSW’s 1-14) 7. Students participate in class discussions of text material. (TSW’s 1-14) 8. ExamView® Computer Test Generator 9. Teacher generated or published Pearson Interactive Science Assessments including Chapter Test, Performance Assessment and Progress Monitoring Assessments (TSW’s 1-10) RUBRIC FOUND ON FOLLOWING PAGE........................... 15 QSI 12/13 LIFE SCI E03 Copyright © 1988-2011 16 QSI 12/13 LIFE SCI E03 Copyright © 1988-2011 ESSENTIAL UNIT 3 (E03) (Genetics) Suggested Rubric The following rubric may be used by the teacher to distinguish between ‘A’-level and ‘B’level work in E03. TSW’s which do not lend themselves to ‘A’-level work do not have suggestions. ‘A’-level Statement ‘B’-level TSW 1 Mendel Student is able to describe Mendel’s experiments, evaluate their results and explain their importance to the study of genetics. TSW 2 Alleles Student can identify the role of alleles in controlling the appearance and inheritance of traits. Student can use Punnett squares showing a Student can use Punnett squares showing a single trait to explain the difference between single trait to explain the difference between genotype and phenotype and explain how genotype and phenotype. the squares can be used to illustrate probability of inheritance of a specific trait. Student can describe and give examples for Student can give examples of four complex four complex patterns of inheritance. patterns of inheritance. TSW 3 Punnett squares TSW 4 Patterns of inheritance TSW 5 inheritance TSW 6 DNA, genes, chromosomes Student can describe the relationship between DNA, genes and chromosomes and how Sutton recognized their roles in inheritance. Student is able to describe the results of Mendel’s experiments and explain their importance to the study of genetics. Students discuss inheritance as combination of environmental and genetic factors. Student can describe how genes make up DNA and DNA is folded to form chromosomes and recognize that chromosomes play a role in inheritance. TSW 7 meiosis Student can illustrate and relate the events that occur during meiosis, comparing and contrasting them with the steps of mitosis. Student can relate the events that occur during meiosis, comparing and contrasting them with the steps of mitosis, using an illustration as a guide. TSW 8 Protein synthesis and RNA In addition to B-level work, student can give a detailed explanation of the process of protein synthesis. Student can describe protein as being made of a combination of as many as 20 different amino acids and that tRNA and mRNA work together to create proteins with information using information received from DNA in the nucleus. Student can explain how human traits are controlled in different ways and give one example for each, recognizing that multiple allele control means multiple alleles exist, but an individual has only two of those alleles. Student can explain three different ways genetic disorders can be inherited in humans and list different methods for diagnosing and treating them. TSW 9 Human traits TSW 11 Genetic disorders Student can explain at least four different ways genetic disorders can be inherited in humans and describe different methods for diagnosing and treating them. 17 QSI 12/13 LIFE SCI E03 Copyright © 1988-2011