Principal Investigator/Program Director (Last, First, Middle): Visootsak, Jeannie OTHER SUPPORT ACTIVE 1K23HD058043-01A1 NIH/NICHD 02/01/09-02/01/13 9 calendar month $513,000 Mentored Patient-Oriented Research (POR) Career Development Award Title: Neurodevelopmental Impact of Congenital Heart Defects in Down Syndrome Role of Project: Principal Investigator Novartis Pharmaceuticals 09/01/10-05/31/12 .6 calendar month $329,927 Title: A randomized, double-blind, placebo-controlled, parallel group study to evaluate AFQ056 in adult patients with Fragile X Syndrome Role of Project: Principal Investigator Novartis Pharmaceuticals 01/15/11-09/01/12 .12 calendar month $274,329 Title: A randomized, double-blind, placebo-controlled, parallel group study to evaluate the efficacy and safety of AFQ056 in adolescent patients with Fragile X Syndrome Role of Project: Principal Investigator Novartis Pharmaceuticals 12/01/11-12/01/12 .12 calendar month $276,162 Title: An open-label study to evaluate the long-term safety, tolerability and efficacy of AFQ056 in adult patients with Fragile X Syndrome Role of Project: Principal Investigator Novartis Pharmaceuticals 02/01/12-02/01/14 .12 calendar month $451,505 Title: An open-label study to evaluate the long-term safety, tolerability and efficacy of AFQ056 in adolescent patients with Fragile X Syndrome Role of Project: Principal Investigator Seaside Therapeutics 04/27/2011-05/01/2013 .3 calendar month $115,000 Title: A Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy, Safety, and Tolerability of STX209 (Arbaclofen) Administered for the Treatment of Social Withdrawal in Children with Fragile X Syndrome Role of Project: Principal Investigator Seaside Therapeutics 04/27/2011-05/01/2013 .3 calendar month $115,000 Title: A Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy, Safety, and Tolerability of STX209 (Arbaclofen) Administered for the Treatment of Social Withdrawal in Adolescents with Fragile X Syndrome PHS 398 (Rev. 11/07) Page Other Support Format Page (continued) Principal Investigator/Program Director (Last, First, Middle): Visootsak, Jeannie Role of Project: Principal Investigator Seaside Therapeutics 12/01/2011-12/01/2012 .12 calendar month $260,161 Title: An Open-Label Extension Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of STX209 (Arbaclofen) in Subjects with Fragile X Syndrome Role of Project: Principal Investigator PHS 398 (Rev. 11/07) Page Other Support Format Page (continued)