MIAMI-DADE COUNTY PUBLIC SCHOOLS
Student BYOD Resource Page
BIOLOGY I HONORS
Course Code: 200032001
TOPIC XXI: MOLECULAR GENETICS - DNA and Replication
Pacing
Date
Traditional 4 days
Block
ESSENTIAL CONTENT
A. Experiments and History**
1. Bacterial Transformation (16.12)
2. Experiments: (Griffith, Hershey & Chase)
2 days
03-16-16 to 03-30-16
03-16-16 to 03-30-16
INSTRUCTIONAL TOOLS
 Summarize the experiments that lead to the discovery of Core Text Book: Ch. 12 all sections
DNA as the genetic material, its structure, location in the
Vocabulary:
cell, and function. **
 Explain that the basic components of DNA are universal DNA, Nucleotide, RNA, Messenger RNA, Double helix,
B. Universal code for all organisms (16.9)
Base pairing, Nitrogenous base, Hydrogen bonding,
in organisms.
1. Role of DNA
Replication, DNA polymerase, Transcription, RNA
 Show that the basic components of DNA are
2. Similarities evidence of ancestry
Polymerase, Transformation, Mutation, Mitosis, Meiosis,
universal in organisms and that similarities in the
Thymine, Adenine, Guanine, Cytosine, RNA splicing,
genetic codes of organisms are due to common
C. Review of Structure of DNA and location in the cell**
Bacteriophage, Virus, Gamete, Codon, Template
ancestry .(ALD)
1. Components of DNA
 Identify the nitrogen base pairs found in DNA and
Technology:
2. Double helix
summarize its structure.
3. Location in cell and importance
 Identify and describe the primary function of nucleic 1. HHMI: Building Blocks of DNA
4. Genes
2. HHMI: DNA replication animation
acids in organisms. (ALD)
 Explain the basic processes of DNA replication and/or its 3. Art in Motion: DNA and genetic material
D. Role of Nucleic acids in organisms (18.1)
4. Interactive Art: DNA Replication
role in the transmission and conservation of genetic
1. Primary function
5. Art Review: DNA Replication- Eukaryotic and
information.
2. Molecular structure
Prokaryotic
 Distinguish among the cellular processes of DNA
6.
Art
in Motion: Hershey Chase Experiment
replication, transcription, and translation. (ALD)
E. DNA Replication in Cell Cycle (16.3, 16.17)
7. Tutor Tube: Memory Tricks for Base Pairing
 Describe gene and chromosomal mutations in the DNA
1. DNA template
8. Bozeman Podcast: DNA & RNA Part 1
sequence.
2. DNA polymerase
9. Bozeman Podcast: DNA & RNA Part 2
 Explain how gene and chromosomal mutations may or
3. Cell cycle (S Phase); Mitosis, Meiosis, and Mutations
10. Bozeman Podcast: DNA Replication
may not result in a phenotypic change.
4. Location of process (nucleus)
11. Bozeman Podcast: What is DNA?
 Apply knowledge of gene and chromosomal
12. Khan Academy: DNA
mutations and interpret how these mutations may or
F. Types of Mutations and effects
13. HippoCampus Biology: DNA Discovery & Structure:
may not result in a phenotypic change. (ALD)
1. Effects on offspring (16.4)
Overview
2. Effects on individual: Cancer (16.8)
14. HippoCampus Biology: Discovery
15. HippoCampus Biology: Structure
16. HippoCampus Biology: Implications
17. HippoCampus Biology: DNA Discovery & Structure:
Summary
18. HippoCampus Biology: DNA Replication: Overview
19. HippoCampus Biology: The Mechanism
20. HippoCampus Biology: The Accuracy of Replication
21. HippoCampus Biology: DNA Replication: Summary
22. Edgenuity
23. Extended Learning Modules
Division of Academics – Department of Science
Third Nine Weeks
OBJECTIVES
Page 1 of 7
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Student BYOD Resource Page
BIOLOGY I HONORS
SC.912.L.16.3
Course Code: 200032001
Building DNA
DNA Fingerprint Analysis
Video
Standard:
SC.912.L.16.3
Image
Article
 James Watson and Francis Crick: DNA
Molecule Has the Form of a Double
Helix
 Rosalind Franklin and Maurice Wilkins:
X-Ray Crystallography of DNA
 DNA: Deoxyribonucleic Acid
 Chromatin, Chromosomes, and DNA
Subunits
 Genes
 The Importance of DNA
 DNA double helix
 Cell with chromosomes and genes
highlighted
 Direction of transcription
 Franklin, Rosalind Elsie
 Polymerase Chain Reaction
 RNA
Standard:
SC.912.L.16.4
Video
 The Role of DNA in Genetic Variation
Between and Among Species
Standard:
SC.912.L.16.8
Video
 Gene Mutation Research
 Free Radicals and Genetic Mutations
Division of Academics – Department of Science
Third Nine Weeks
 Nucleic Acids
 Messenger RNA: Transcribing the
Message
 The Central Dogma: DNA Replication
 The Central Dogma: RNA and
Transcription
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MIAMI-DADE COUNTY PUBLIC SCHOOLS
Student BYOD Resource Page
BIOLOGY I HONORS
Standard:
SC.912.L.16.9
Standard:
SC.912.L.16.12
Course Code: 200032001
Video
 Introduction to the Genetic Code
 The Language of Life
 The Genetic Code
 Video Quiz: Part One
Video
 Gel Electrophoresis
 The Riddle of Life: DNA
 Manipulation of DNA: Using Isolated
Genes in the Process of Bacterial
Transformation
 Molecules, Compounds, and
Macromolecules
 Macromolecules
 Carbohydrates
 Lipids: Fats and Oils
 The Structure of the Cell: Proteins and
Enzymes





Video
Standard:
SC.912.L.18.1
Audio
Proteins
An Introduction to Proteins
Proteins and Amino Acids
Protein Shapes Revisited
Lipids & Cholesterol
 What Is Protein?
 Structures and Functions of Different
Proteins in the Body
 Nucleic Acids
 Nucleic Acids
Article
Standard:
HE.912.C.1.7
Video
Division of Academics – Department of Science
Third Nine Weeks
 Cystic Fibrosis
 Diabetes
 DNA and the Genetics of Cancer
 Genetic Disease
Page 3 of 7
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Student BYOD Resource Page
BIOLOGY I HONORS
Course Code: 200032001
Video
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
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DNA Evidence Links Albert DeSalvo to Boston Strangler Murders
Supreme Court Rules DNA Samples Allowed in Arrests for Serious Crimes
DNA Evidence: Powerful Tool or Privacy Violation?
Richard III Found in a Parking Lot
Researchers: "Junk DNA" Plays Critical Role
Tomato: DECODED
Convictions Based on Hair Analysis Under Review
Researchers Map DNA of Fetus from Blood and Saliva of Parents
DNA Testing Connects Unlikely Cousins
DNA Testing: How Accurate Is It? And How Is It Done?
Division of Academics – Department of Science
Third Nine Weeks
Page 4 of 7
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Learning Goals
BIOLOGY I HONORS
Course Code: 200032001
SC.912.L16.3: Describe the basic process of DNA replication and how it relates to the transmission and conservation of the genetic information. ( Cognitive Complexity: Level 3:
Strategic Thinking & Complex Reasoning)
SC.912.L16.5: Explain the basic processes of transcription and translation and how they result in the expression of genes. ( Cognitive Complexity: Level 3: Strategic Thinking &
Complex Reasoning )
SCALE
LEARNING PROGRESSION

I am able to distinguish among the cellular processes of DNA replication,
transcription, and translation.

I am able to differentiate the cellular processes of DNA replication, transcription, and
translation.
Create a diagram demonstrating the processes of DNA
replication, transcription and translation. Include descriptions
of each process and how they differ from one another.

I am able to differentiate the cellular processes of DNA replication, transcription, and
translation.
Given a diagram of the processes of DNA replication,
transcription and translation, identify the correct sequence of
each process.

I am able to choose the correct cellular process of DNA replication.
Given a diagram of the components of DNA replication,
identify the correct sequence of replication.

I am able to understand that every organism has hereditary information stored in
DNA that get passed on from one generation to another.
Score/Step 4.0
Score/Step 2.0
Score/Step 1.0
Using a given DNA nucleotide sequence, trace the pathway
from replication to transcription and translation.
Identify the corresponding protein sequence that will form
based on the original DNA nucleotide sequence and what
could occur if the original DNA sequence was changed in any
way.
Score/Step 5.0
Score/Step 3.0
Target
(Learning Goal)
SAMPLE PROGRESS MONITORING AND ASSESSMENT
ACTIVITIES
Division of Academics – Department of Science
Third Nine Weeks
Page 5 of 7
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Learning Goals
BIOLOGY I HONORS
Course Code: 200032001
SC.912.L16.8: Explain the relationship between mutation, cell cycle, and uncontrolled cell growth potentially resulting in cancer. (Cognitive Complexity: Level 2: Basic Application
of Skills & Concepts)
SCALE
LEARNING PROGRESSION
SAMPLE PROGRESS MONITORING AND ASSESSMENT
ACTIVITIES

I am able to assess how uncontrolled cell growth may result from mutations that
affect the proteins that regulate the cell cycle.
Describe how to prevent cancer by preventing mutations.

I am able to assess how uncontrolled cell growth may result from mutations that
affect the proteins that regulate the cell cycle.
Given a scenario of a patient just diagnosed with cancer,
trace the history of those cancer cells back to when they
were healthy.

I am able to state that mutations that affect the proteins that regulate the cell cycle
may result in uncontrolled cell growth.
Sequence the events that result in uncontrolled cell growth:
certain proteins regulate checkpoints in the cell cycle so that
it proceeds normally, a mutation occurs in the DNA of a
gene of one of these proteins, the wrong protein is made,
the checkpoint is no longer properly regulated, cells divided
without control.

I am able to recall that uncontrolled cell growth may result in cancer.
Given two difference sequences that show normal cell
division and uncontrolled cell division, describe the end
result of each sequence.

I am able to recall that cells divide in order to make more cells.
Score/Step 5.0
Score/Step 4.0
Score/Step 3.0 Target
(Learning Goal)
Score/Step 2.0
Score/Step 1.0
Division of Academics – Department of Science
Third Nine Weeks
Page 6 of 7
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Learning Goals
BIOLOGY I HONORS
Course Code: 200032001
SC.912.L.18.1: Describe the basic molecular structures and primary functions of the four major categories of biological macromolecules. ( Cognitive Complexity: Level 2: Basic
Application of Skills & Concepts )
SCALE
LEARNING PROGRESSION
SAMPLE PROGRESS MONITORING AND ASSESSMENT
ACTIVITIES

I am able to summarize the basic molecular structure and the primary function of
macromolecules in organisms.
Develop an argument for each macromolecule and justify
their level of importance in various organisms.

I am able to summarize the basic molecular structure and the primary function of
macromolecules in organisms.
Construct models of each of the four macromolecules and a
Venn diagram that compares and contrasts the molecules
based on elemental composition, structure, function.

I am able to identify the basic molecular structure and the primary function of
macromolecules in organisms.
Create a foldable that names the four macromolecules,
describes two major functions of each, and identifies the
basic molecular structure.

I am able to identify the primary function of the four macromolecules in organisms.
Match each macromolecule to a brief description of the
various functions.

I am able to recognize that there are four macromolecules.
Score/Step 5.0
Score/Step 4.0
Score/Step 3.0 Target
(Learning Goal)
Score/Step 2.0
Score/Step 1.0
Division of Academics – Department of Science
Third Nine Weeks
Page 7 of 7