Nexium Control Product Factsheet
Date of preparation: 16th February 2015
NEXIUM CONTROL® – PRODUCT FACTSHEET
Life without heartburn
One in three people in the UK experience heartburn symptoms and one in six experience frequent
heartburn1, which occurs two times per week or more.2 Those unfortunate enough to suffer from
frequent heartburn can often feel limited in their food and drink choices,3 suffer from sleep
disruption4 and feel generally unwell. However, frequent heartburn sufferers can now buy Nexium
Control® for 24-hour protection from heartburn.
Traditional heartburn treatments such as antacids are designed to give temporary relief from the
pain of heartburn. They work reactively by neutralising the acid5 but don’t tackle acid production.
They need to be taken repeatedly to maintain their effect.
Nexium Control® is different. As a proton pump inhibitor (PPI), Nexium Control® targets heartburn at
its source by blocking acid production in the stomach. Just one tablet a day can provide 24-hour
protection from frequent heartburn.6
About frequent heartburn
Heartburn is a painful condition caused by stomach acid rising up into the food pipe (oesophagus),
touching its unprotected lining.3 Everyone experiences heartburn differently, but the most common
symptom is burning pain under the breastbone.3 Some people experience a nasty taste or fluid in the
back of the throat.3 Frequent heartburn is often defined as that which occurs twice a week or more.2
Comparison of heartburn treatments:
More traditional heartburn treatments fall short of providing the 24-hour symptom relief that frequent
sufferers need.
Duration of
action
Dosing
Mechanism
of action
Key benefit
Antacids5
Up to 2 hours
Alginates5
Up to 4 hours
H2 blockers7
Up to 12 hours
Multiple daily
doses in
response to
flare-ups
Neutralise acid
Multiple daily
doses in response
to flare-ups
Multiple daily
doses
Quick relief of
symptoms
Quick relief of
symptoms
Form a protective Block one of the
raft at the top of
three signals
stomach contents that stimulate
acid production
Intermediate
duration of
relief
Nexium Control®6
24-hour
protection
1 daily dose
Act on proton
pumps to block
acid production
and provide
protection
Continuous 24hour protection
from heartburn*
*Nexium Control® gets to work in 1 hour and some people may experience protection from heartburn that day
or by the evening. Full effect may take 2-3 days.
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Nexium Control Product Factsheet
How does Nexium Control® work?
Nexium Control® contains esomeprazole which is a proton pump inhibitor (PPI). It is a treatment that
blocks the proton pumps which are responsible for secreting acid into the stomach, thereby
protecting you from heartburn.6
By treating the source of acid production rather than just the symptoms, one Nexium Control® tablet
can give continuous 24-hour protection against heartburn.6 Nexium Control® can be taken for up to
14 consecutive days and is available in 7 or 14 tablet packs.
With just one Nexium Control® tablet per day 8 out of 10 frequent heartburn sufferers saw a
meaningful improvement in their symptoms within one week6. Providing day-long protection against
heartburn, users can feel confident and reassured that their food choices or lifestyle will not be
impacted by heartburn.
The medicine in Nexium Control® (esomeprazole) has been prescribed to millions of patients for
over a decade. Nexium Control® is the number 1 acid blocker brand worldwide8 and is now available
to buy without prescription due to a reclassification of the license.
Fast facts
 Nexium, the No 1 acid blocker brand worldwide8, was originally developed by AstraZeneca, a
company with a rich heritage of almost 50 years of research.
 The medicine in Nexium Control® has been prescribed to millions of patients for over a decade
and is now available over the counter for frequent heartburn.
 Nexium Control® has been licensed by the European Medicines Agency (EMA) for all 28
countries in the European Union.
Nexium Control® 20mg gastro-resistant tablets for the short-term treatment of reflux symptoms
(e.g. heartburn and acid regurgitation) in adults. Active ingredient: Esomeprazole. Always read the
leaflet.
Nexium Control® is available in supermarkets and pharmacies nationwide, in packs of 7’s and 14’s
at a RRP £6.99 and £11.99 respectively. Always read the label. If symptoms persist or worsen,
people should see a GP for further advice. For more information visit www.nexiumcontrol.co.uk
ENDS
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Email:
Issued by:
On behalf of:
Notes to editors:
Luke Hopkins (01273 712023) or Laura Cook (01273 712064)
lhopkins@thisispegasus.co.uk or lcook@thisispegasus.co.uk
Pegasus
Pfizer Consumer Healthcare
When to see a doctor with frequent heartburn
Those taking Nexium Control® should see a doctor if symptoms worsen or do not improve after taking the medication for
14 days in a row. In addition those who experience unintentional weight loss, long-term or bloody vomiting, or tarry stools,
those who regularly take painkillers or anti-inflammatory drugs and those with a history of gastric or duodenal ulcers, or
renal or hepatic impairment should see their doctor.
People are also advised to visit a pharmacist or GP if:
They are taking any medications listed in the Nexium Control® package leaflet – available:
https://www.medicines.org.uk/emc/PIL.29819.latest.pdf
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Nexium Control Product Factsheet
-
They are over the age of 55 and have new or recently change acid reflux symptoms
About Pfizer: Working together for a healthier world™
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the standard for quality, safety and value in the discovery, development and manufacturing of medicines. Our diversified
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more about our commitments, please visit us at www.pfizer.co.uk.
References
1
Data on file. Forbes Consulting Group Usage and Attitude Study.2013
Fennerty MB, Finke KB, Kushner PR, et al. Short- and long-term management of heartburn and other acid-related
disorders: development of an algorithm for primary care providers. J Fam Pract. 2009;58(7 suppl):S1-S12.
2
3
NHS Choices. Symptoms of gastro-oesophageal reflux disease. Introduction. www.nhs.uk/Conditions/Gastroesophageal-refluxdisease/Pages/Introduction.aspx Accessed Feb 2015
4
Farup C at al. Arch Intern Med. 2001; 161:45-52.
Mandel KG at al. Ailment Pharmacol Ther. 2000;14:669-90
6 Nexium Control SPC. Available at: https://www.medicines.org.uk/emc/medicine/24695.
7
http://www.medicines.org..uk/emc/mecine/24549.
8
IMS 2014 based on worldwide value sales data
5
3