2010 Classification Project Kylee Payne Pharmacology 3/16/2010 Kylee Payne 2010 Table of Contents Nervous System 3 Psychiatric Drugs 8 Analgesics 12 Cardiac System 16 Respiratory System 21 Gastrointestinal System 24 Endocrine System 27 Antibacterials 29 PDRs 32 Page 2 Kylee Payne 2010 Nervous System Page 3 Kylee Payne 2010 Classifications Indications Beta-adrenergenic blockers Hypertension, Angina Pectoris, MI, are important to those who have survived their first MI, Migraine, Part of the standard therapy for CHF, May increase survival rate if taken prior to coronary artery bypass surgery. Cholinergic Anticholinergic Contraindications Sinus bradycardia, 2nd/3rd degree AV block, CHF unless secondary to tachycarrythmia treatable with betablockers, overt cardiac failure. chronic bronchitis, bronchial asthma or history thereof, bronchospasm, emphysema, severe COPD Treat Myasthenia cardiovascular disease, Gravis, Glaucoma, used hypertension, in surgery to prevent bronchospastic disease, urinary retention post diabetes mellitus, operatively, also to pheochromocytoma, counteract the effects peripheral vascular of the muscle relaxants disease, used in surgery hyperthyroidism, , hepatic disease, children under age 18, lactation Gastrointestinal Glaucoma, tachycardia, disorders, gastritis, myocardial ischemia, pylorospasm, hemorrhage, diverticulitis, ulcerative hypertrophy, ulcerative Page 4 Side Effects Bradycardia, hypotension, CHF, cold extremities, claudication, worsening of angina, strokes, edema, syncope, arrhythmias, chest pain, periperhal ischemia, flushing, SOB, sinoatrial block, pulmonary edema, vadsodilation, increased HR, palpitations, conduction disturbances headache, dizziness, drowsiness, poor concentration, nervousness, weakness, paresthesia, insomnia, abnormal dreams, chest pain, hypertension, tachycardia, N&V, diarrhea, constipation, abdominal pain, dry mouth, dyspepsia; Dysphagia, constipation, heartburn, bloated feeling, change in taste perception, dizziness, Examples Lopressor Naldol Humersol Aricept Atropine dicyclomine Kylee Payne 2010 Skeletal muscle relaxants Sedative-hypnotic Anti-epileptic colitis, genitourinary disorders ,cystitis, urethritis, prostatitis, respiratory disorders, asthma, chronic bronchitis, Parkinson’s disease, Sinus bradycardia colitis, liver or kidney disease, high blood pressure, an overactive thyroid, nervous system disorders, all stomach/intestinal problems, glaucoma, enlarged prostate, allergies. headache, weakness, insomnia, blurred vision, skin rashes, nasal congestion, lactation, confusion, tremors, rapid/irregular heartbeat, difficulty urinating Musculoskeletal and neurologic disorders associated with muscle spasms, hypereflexia, and hypertonia, parkinsonism, tetanus, tension headaches, acute muscle spasms caused by trauma, and inflammation, management of MS and Cerebral Palsy Short term treatment of insomnia, difficulty with sleep onset/sleep maintenance Hypersensitivity, rheumatic disorders, spasm from Parkinson's disease, stroke, cerebral palsy. Intrathecal product for IV, IM, SC, or epidural use. Drowsiness, hypotension, dizziness, headache, insomnia, fatigue, confusion, nausea, constipation, urinary frequency, hypotonia, somnolence, dizziness, convulsions, constipation, N&V, headache, paresthesia. Baclofen Diazepam Lactation Ambien Restoril Sedative or hypnotic, Hypersensitivity to Dizziness, drowsiness, drugged feeling, headache, nausea, diarrhea, dyspepsia, myalgia, URTI, somnolence, nasopharyngitis Sleepiness, agitation, Page 5 Phenobarbitol Kylee Payne 2010 preanesthetic, anticonvulsant, emergency control of acute seizure Anti-parkinson Parkinsonism, rigidity, bradykinesia, tremors, dysphagia, seborrhea, sialorrhea, and postural instability, carbon monoxide and manganese intoxication barbiturates, severe trauma, pulmonary disease when dyspnea or obstruction is present, edema, uncontrolled diabetes, history of porphyria, and impaired liver function, previous addiction to sedativehypnotics, lactation CNS depression, hypotension, marked asthenia, hypoadrenalism, and severe myxedema, porphyria, fever, anemia, hemorrhagic shock, cardiac, hepatic or renal damage, alcoholism History of melanoma, lactation, MAO inhibitors, except MAOB inhibitors hypersensitivity to drug, narrow-angle glaucoma, blood dyscrasias, hypertension, coronary sclerosis. Page 6 confusion, hyperkinesia, ataxia, CNS depression, nightmares, nervousness, psychiatric disturbances, hallucinations, insomnia, anxiety, dizziness, headache, abnormal thinking, vertigo, lethargy, hangover, excitement, hypoventilation, apnea , respiratory depression . bradycardia, hypotension, syncope, circulatory collapse . N&V, constipation, liver damage Carbemazepine Choreiform, dystonic movements, anorexia, N&V, abdominal pain, dry mouth, dysphagia, dysgeusia, headache, dizziness, sialorrhea, malaise, fatigue, euphoria, dyskinesias Levadopa Carbidopa Kylee Payne 2010 Anti-convulsant Control or prevent seizures Low bone mineral density Page 7 Increased risk of suicidal behavior, Gabapentin Phenytoin Kylee Payne 2010 Psychiatric Drugs Page 8 Kylee Payne 2010 Classifications Indications Contraindications Side Effects Examples Antipsychotic Psychoses, involutional, toxic, or senile psychoses, depression, anxiety, agitation, or acute manic phase of manic-depressive illness, as an adjunct in alcohol withdrawal, severe behavioral problems in children, manifested by hyperexcitable and aggressive behavior Severe CNS depression, coma, subcortical brain damage, bone marrow depression, lactation, history of seizures and in those on anticonvulsant drugs, hepatic or renal disease, CV disorders, glaucoma, prostatic hypertrophy, children with chickenpox, CNS infections, measles, gastroenteritis Depression, drowsiness, dizziness, lethargy, fatigue, Parkinson-like symptoms including shuffling gait or tic-like movements of head and face, tardive dyskinesia, akathisia, dystonia, Seizures, Orthostatic hypotension, increase or decrease in BP, tachycardia, fainting dry mouth, anorexia, constipation, diarrhea. Abilify Chlorpromazine hydrochloride Antianxiety Short-term relief of anxiety disorders or symptoms of anxiety with depression preanesthetic, status epilepticus. Narrow angle glaucoma, kids under 12 years of age Drowsiness, ataxia, confusion, clumbsiness, N & V, diarrhea, headache Xanax Lorazepam Stimulants (ADHD) in children over 3 years of age, moderate to severe distractibility, short Use in children less than 3 years of age for ADD, in children less than 6 years of Decreased appetite, upset stomach, insomnia, increased anxiety, irritability, Adderall Ritalin Page 9 Kylee Payne 2010 Antidepressants attention span, hyperactivity, emotional lability, and impulsivity, narcolepsy in adults and children over 6 years of age. age for narcolepsy, or in children or adults with a structural cardiac abnormality, use as an appetite suppressant, Marked anxiety, tension and agitation, glaucoma. severe depression, to prevent or treat normal fatigue, diagnosis or family history of Tourette's syndrome, motor tics. In children who manifest symptoms of primary psychiatric disorders Headache, URTI, abdominal pain, anorexia, insomnia, vomiting, accidental injury, nervousness. Endogenous and reactive depressions, anxiety, and sleep disturbances. SSRI’s are most commonly used Severely impaired liver function. Use during acute recovery phase from MI. Concomitant use with MAO inhibitors. ataxia, anxiety, coma, confusion, disorientation, disturbed concentration, dizziness, drowsiness, dysarthria, incoordination, insomnia, mania, neuroleptic malignant syndrome, numbness, panic, Page 10 Effexor Fluoxetine Kylee Payne 2010 paresthesias of extremities, peripheral neuropathy, tremors, seizures, restlessness, weakness,dry mouth, blurred vision, N&V, abdominal pain Page 11 Kylee Payne 2010 Analgesics Page 12 Kylee Payne 2010 Classifications Narcotic (Opioid) analgesics Non-Opioid Salicylates Indications Contraindications Side Effects Examples Treat pain due to various causes (MI, carcinoma, surgery,burns, postpartum) Preanesthetic medication, Adjunct to anesthesia, Acute vascular occulusion, Diarrhea, Antitussive Asthma, emphysema, kyphoscoliosis, sever obesity, convulsive state as in epilepsy, delirium tremens, tetanus and strychnine poisoning, diabetic acidosis, myxedema, Addison’s disease, hepatic cirrhosis, and children under 6 months liver disease, asthma, kidney disease, a history of drug or alcohol abuse Dizziness, lightheadedness, sedation, lethargy, headache, euphoria, mental clouding, fainting, tremors, insomnia, N&V, vomiting, constipation, dry mouth, anorexia, flushing, skin rashes, sweating. Morphine sulfate Oxycodone hydrochloride Constipation, diarrhea, dizziness, dry mouth, indigestion, nausea, nervousness, skin itch, sleepiness, stomach aches, sweating, vomiting, weakness, hives, itching, bruising, fever, sore throat Tramdol Acetominaphen Hypersensitivity, asthma, hay fever, or nasal polyps, severe anemia, Dyspepsia, nausea, epigastric discomfort. The toxic effects of Asprin Ascriptin Non narcotic pain reliever Pain, myalgias, neuralgias, arthralgias, headache, Page 13 Kylee Payne 2010 Antigout dysmenorrhea, gout, ess severe postoperative and postpartum pain; pain secondary to trauma and cancer, arthritis, osteoarthritis, SLE, acute rheumatic fever history of blood coagulation defects, in conjunction with anticoagulant therapy, can cause congestive failure when taken in the large doses used for rheumatic diseases, vitamin K deficiency, 1 week before and after surgery. In pregnancy, in children or teenagers with chickenpox or flu due to possibility of development of Reye's syndrome. the salicylates are dose-related, dyspepsia, heartburn, anorexia, nausea, occult blood loss, epigastric discomfort, massive GI bleeding, potentiation of peptic ulcer,skin rashes, angioedema, urticaria, rhinitis, nasal polyps, thrombocytopenia, leukopenia, purpura, shortened erythrocyte survival time, decreased plasma iron levels, thirst, fever, dimness of vision. Hyperuicemia in chronic gout and gouty arthritis,Adjunct in therapy with penicillins or chephalsporins to elevate and prolong plasma antibiotic levels Hypersensitivityto drug, blood dyscrasias, uric acid and kidney stones. Use for hyperuricemia in neoplastics disease or its treatment, Use in children less than 2 years of age, concomitant use of salicylates or use with Headache, dizziness, norexia, N&V, diahrrea, constipation, skin rash, abdominal discomfort, urinary frequency, Page 14 Apo-sulfinpyrazone Benuryl Kylee Payne 2010 NSAIDs Antipruritic Inflammatory disease, including rheumatoid arthritis, osteoarthritis, gout, Mild to moderate pain including primary shoulder, synovitis, tendinitis, dental pain, strains and sprains. Reduce risk of prostate cancer and Alzheimer’s disease. Used to treat a variety of skin conditions (eczema, dermatitis, allergies, rash, swelling, itching, and redness. penicillin in renal impairment Most for children under 14 years of age, lactation, individuals in whom asprin, NSAIDs, or iodides have caused hypersensitivity, including acute asthma, rhinitis, urticaria, bronchospasms, Don’t use if there is an infection or sore in the area treated, children maybe more sensitive to the effects, pregnancy –as needed Page 15 N&V, anorexia, diarrhea, constipation, increased or decreased appetite, indigestion, abdominal cramos or pain, dizziness, drowsiness, headaches, nervousness, migraine, anxiety, mental confusion, chest pain, inability to concentrate. Stinging, buring, itching, dryness, redness, acne,dizziness, trouble breathing. Ibuprofen Ketoprofen Cortaid Lanacort Kylee Payne 2010 Cardiac System Page 16 Kylee Payne 2010 Classifications Indications Contraindications Side Effects Examples Cardiac glycosides Treats heart failure, CHF, control of rapid ventricular contraction with atrial fibrillation or flutter, cardiogenic shock Blurred vision, hives, rash, diarrhea, loss of appetite, nausea, stomach pain, vomiting, confusing, depression, fainting. Digoxin Lanoxin Antiarrythmics CHF,venous congestion, edema, dyspnea, orthopnea, and cardiac arrhythmia, control of rapid ventricular contraction rate in clients with atrial fibrillation or flutter, slow HR in sinus tachycardia due to CHF, SVT, prophylaxis and treatment of recurrent paroxysmal atrial tachycardia with paroxysmal AV junctional rhythm. Tachycardia, headache, dizziness, mental disturbances, N&V, diarrhea, anorexia, blurred or yellow vision Adenosine Verapamil Antianginal Treatment and prophylaxis of Venticular fibrillation or tachycardia,( unless congestive failure after protracted episode not due to digitalis), Hypersensitivity to cardiac glycosides,beriberi heart disease. Ventricular fibrillation or tachycardia (unless congestive failure supervenes after protracted episode not due to digitalis), in presence of digoxin toxicity, hypersensitivity to cardiac glycosides, beriberi heart disease, certain cases of hypersensitive carotid sinus syndrome, ischemic heart disease, acute myocarditis, hypertrophic subaortic stenosis, hypoxic or myxedemic states Sensitivity to nitrites, Headaches, Nitroglycerin Page 17 Kylee Payne 2010 acute angina pectoris, First-line therapy for unstable angina, Adjunct in treating hypertension or CHF associated with MI Calcium Antagaonists (Calcium Channel Blocker) Antihypertensives Diuretic which may result in severe hypotensive reactions, MI, or tolerance to nitrites. Sever anemia, cerebal hemorrhage, reacent head trama, postural hypotension. Angina pectoris, hypertension, subarachnoid hemorrhage, atrial fibrillation/flutter, paroxysmal supraventricular tachycardia. Sick sinus syndrome, second- or third-degree AV block (except with a functioning pacemaker), use of bepridil, diltiazem, or verapamil for hypotension <90 mm Hg systolic pressure), lactation, hypersensitivity, Treat hypertension, heart failure, Hypersensitivity to post MI, high coronary disease benazepril or any other risk diabetes, chronic kidney ACE inhibitor, Use not disease bad recurrent stroke advised for children prevention less than 6 years of age Edema associated with CHF, nephrotic syndrome, hepatic ethacrynic acid, anuria, hypersensitivity Page 18 restlessness, dizziness, weakness, apprehension, anxiety, insomnia, confusion, nightmares, postural hypotension, tachycardia, hypertension, N&V, dyspepsia, diarrhea, dry mouth, abdominal pain. Peripheral edema, asthenia, dizziness, lightheadedness, headache, dyspepsia, constipation, cough, URTI, flushing, flushing, fatigue/lethargy, edema, peripheral edema, weakness, muscle cramps, disturbed equilibrium. Headache, dizziness, fatigue, somnolence/drowsiness, nausea, cough, postural dizziness, nasopharygitis, hypotension. Jaundice, tinnitus, hearing impairment, Isosorbide dinitrate Nifedipine Felodipine Lotensin Diovan HTC Lasix Furosimide Kylee Payne 2010 cirrhosis, and ascites, acute pulmonary edema, hypertension in conjunction with spironolactone, triamterene, and other diuretics except ethacrynic acid. to drug, severe renal, azotemia and oliguria, hepatic coma associated with electrolyte depletion, lactation. hypotension, water/electrolyte depletion, pancreatitis, abdominal pain, dizziness, anemia. Anticoagulant Prophylaxis of blood clots, decrease clotting ability of blood Hypersensitivity, lactation, pregnancy, kids 12 and under, adults over 60, Antiplatelet Reduce symptoms associated with exercise in pulmonary Known hypersensitivity to the drug or bleeding gums, sores or white spots in the mouth or throat, bruising, unexplained nosebleeds, unusually heavy bleeding or oozing from wounds, unexpected or unusual menstrual bleeding, blood in the urine, cloudy or dark urine, painful or difficult urination or sudden decrease in amount of urine, black, tarry, or bloody stools, coughing up blood, vomiting blood or something that looks like coffee grounds, constipation Bleeding, bradycardia, coronary artery Page 19 Coumidin Warfarin Remodulin Aggrastat Kylee Payne 2010 Antihyperlipidemics Vasodilators arterial hypertension, Deminish rate of clinical deterioration in clients requiring transition form epprrpstenol, ACS, Heterozygous familial hypercholesterolemia in adolescents, homozygous familial hyperlipidemia, hypertriglyceridemia, mixed dyslipidemia, primary dysbetalipoproteinemia, primary hypercholesterolemia,heterozygous familial and nonfamilial structurally-related compounds dissection, pelvic pain, dizziness, leg pain. Active liver disease or unexplained persistent elevated liver function tests. Pregnancy, lactation. Use in children Increase blood floow in certain parts of the body, CHF, diabetic neuropathy Heart disease, gloaucoma, Parkinson’ s disease, allergies, lactation effects have been reported for HMG-CoA reductase inhibitors, N&V, diarrhea, constipation, abdominal cramps or pain, flatulence, dyspepsia, heartburn. Anorexia, biliary pain, cheilitis, cholestatic jaundice, cirrhosis, colitis, duodenal ulcer, dysphagia, enteritis, eructation, eosphagitis, fatty changes in liver, Dizziness, flushing, fast pulse, deep breathing, lethargy, rash, dysgeusia, gastric irritation, aphthous ulcers/peptic ulcer, headache, fatigue, drowsiness, malaise, N&V, diarrhea, dry mouth. Page 20 Lipitor Simvastatin papaverine Captopril Kylee Payne 2010 Respiratory System Page 21 Kylee Payne 2010 Indications Contraindications Side Effects Examples Antihistamine Used to treat rash, hives, watery eyes, runny nose, itching and sneezing due to allergies or the common cold. They may also be used to treat motion sickness, anxiety, or as a sleep aid (for insomnia) Drowsiness, dizziness, headache, loss of appetite, stomach upset, vision changes, irritability, dry mouth and nose. Breathing difficulties, pounding or irregular heartbeat, ringing in the ears, difficulty urinating. Allegra Zyrtec Bronchodilators Relaxes the smooth muscle in the lungs and dilates airways to improve breathing. Used in the treatment of asthma, chronic bronchitis and emphysema. Limit alcohol intake to avoid excessive drowsiness. Caution is advised when using in elderly because they may be more sensitive to effects. Hypertension, Do not give to children under 12 years of age, Pregnancy. Overactive thyroid, heart disease, hypertension, epilepsy, diabetes, Nolvadex Xopenex Corticosteroids Reduces swelling, allergic reactions, skin disease (psoriasis, hives), breathing problems, certain cancers, blood disorders and eye Dry mouth, irritated throat, dizziness, headache, lightheadedness, heartburn, loss of appetite, altered taste sensation, restlessness, anxiety, nervousness, trembling, and sweating. Dizziness, nausea, indigestion, increased appetite, weight gain, weakness or sleep disturbances. Vomiting or blood, abnormal stools, muscle Classifications Liver or kidney disease, heart problems, intestinal problems, ulcers, hypertension, TB, osteoporosis, using alcohol aspirin and Page 22 Prednisone Cortisone Kylee Payne 2010 problems, arthritis, digestive problems and hormone replacement certain arthritis medications, pregnancy Antitussive Used to treat dry cough and nasal congestion caused by the common cold, flu, or other respiratory illness. Expectorant Used to treat dry cough and nasal congestion caused by common cold, flu, and other respiratory illness. Loosens mucus in the lungs. Hypertension, severe coronary artery disease, allergic reaction to codeine, hydrocodone, heart problems, kidney disease, liver disease, diabetes, glaucoma, depression, Avoid alcohol, pregnancy. Hypertension, coronary artery disease, depression, Avoid alcohol, pregnancy. Page 23 weakness, breathing difficulties, mood changes, vision changes. Nausea, nervousness, anxiety, headache, dizziness, drowsiness, trouble sleeping, vomiting, constipation, chest pain, rapid/pounding heart, tremors, mood changes, seizures, rash, itching, swelling. Nausea, nervousness, anxiety, headache, dizziness, drowsiness, vomiting, constipation, chest pain, painful/difficult urinating. Codeine dextromethorphan Mucinex Parvolex Kylee Payne 2010 Gastrointestinal System Page 24 Kylee Payne 2010 Classifications Indications Contraindications Side Effects Examples Histamine H2-Receptor antagonists Short-term treatment of benign gastric ulcer. Maintenance therapy after healing of acute ulcer. Treatment of active duodenal ulcer. Hypersensitivity, Use of cimetidine, famotidine, and nizatidine during lactation. Cimetidine Famotidine Proton pump inhibitors Short-term treatment of active duodenal ulcer. Treatment of active benign gastric ulcer. Treatment of heartburn and other symptoms with GERD. Used to relive acid indigestion, upset stomach and heartburn, Help manage GERD. Lactation N&V, abdominal discomfort, diarrhea, constipation, hepatocellular affects, headache, fatigue, dizziness, confusion, insomnia, rash. Chest pain, angina, hypertension, tachycardia, anxiety, dry mouth, anemia, hypoglycemia, gout, weight gain, fever. Avoid if any signs of appendicitis, Avoid if you intake a lot of calcium, Excessive use may increase severity or kidney problems,. None listed. Chalky taste, diarrhea, constipation, abdominal cramps, N&V. Digoxin Itraconazole Drowsiness, dry mouth, nervousness, insomnia, constipation Dramamine Aprepitant In clients in whom constipation should be avoided. OTC if body temperature is over Abdominal Immodium pain/distention/discomfort, Kaopectate II caplets constipation, dry mouth, N&V, distress, Antacids Antiemetic Antidiarrheals Prevention and treatment of N&V, dizziness of motion sickness. Symptomatic relief of diarrhea and of chronic diarrhea, associated with inflammatory bowel Page 25 Nexium Prevacid Kylee Payne 2010 disease. 38C (101F) and in presence of bloody diarrhea. Children under age 3 are more sensitive to the narcotic effects of loperamide. Page 26 dizziness, drowsiness Kylee Payne 2010 Endocrine System Page 27 Kylee Payne 2010 Classifications Indications Contraindications Side Effects Examples Glucocorticoid Adrenal insufficiency, rheumatic, allergic states, respiratory diseases (asthma) Burning, cracking/fissuring of skin, irritation, itching, numbness of fingers reddened skin, skin atrophy,. Temovate Prednisone Estrogen Drugs Hormone replacement therapy in postmenopausal women to relieve moderate to severe vasomotor symptoms and decrease risk of osteoporosis. Component of combination oral contraceptives and other forms for contraception Non-insulin-dependant diabetes mellitus (type 2) that does not respond to diet management and excursive alone. Also helps treat diabetes Use in children less than 12 years old, use for more than 2 weeks, to treat rosacea or perioral dermatitis, and use on face and groin. Known or suspected breast cancer, except in those clients being treated for metastatic disease. Cancer of the genital tract and other estrogen-dependant neoplasm. Use during lactation, known or suspected pregnancy N&V, diarrhea, constipation, abdominal cramps/pain, dyspepsia, enlarged abdomen, change in appetite, rash, UTI, Vaginal discharge, Mental depression, dizziness, changes in libido, insomnia, headache, anxiety. Oral Contraceptives Premarin Ketosis, Severe trauma, fever, infections, pregnancy, diabetes complicated by recurrent episodes of ketoacidosis or coma, juvenile, growth-onset, Insulin dependant. Nausea, heartburn, epigastric fullness, diarrhea,GI pain, constipation, dyspepsia, fatigue, dizziness nervousness, asthenia, insomnia, weakness, skin rash, leg cramps Humulin Glucophage Antidiabetic Page 28 Kylee Payne 2010 Antibacterials Page 29 Kylee Payne 2010 Classifications Indications Penicillins Ear, nose, and throat Hypersensitvity to infections, GU penicillins, imipenem, infections, lower PO use of penicillins respiratory tract during acute stages infections. of empyema, bacteremia, pneumonia, meningitis, pericarditis, use with history of amoxicillin/clavulanate associated cholestatic jaundice or hepatic dysfunction, lactation. Respiratory tract Hypersensitivity to infection, skin chepalosporins or infections, and urinary related antibiotics. tract infections. Cephalosporins Aminoglycosides Gram-negative bacteria causing bone and joint infections, septicemia(including neonatal sepsis) skin and soft tissue Contraindications Hypersensitivity to aminoglycosides, longterm therapy (except streptomycin for tuberculosis). Page 30 Side Effects Examples Diarrhea, abdominal cramps or pain, N&V, bloating, flatulence, increased thirst, dizziness, insomnia, hyperactivity, fatigue. Amoxicillin Penicillin N&V, diarrhea, constipation, abdominal cramps or pain, dyspepsia, heartburn, hypotension, fatigue, asthma, itching, fever chills. Ototoxicity, Renal Imapairment, Neurotoxicity, Coma, and respiratory depression in infants, Allergic rash, N&V Cephalexin Cefzil Gentamicin Sulfate Neomycin Sulfate Kylee Payne 2010 Sulfonamides infections(including those from burns), respiratory tract infections, postoperative infection, Intraabdominal infections (including peritonitis).UTIs. Urinary tract infections, chancroid, Meningitis, Rheumatic fever, Nocardiosis, Trachoma, STI. Tetracyclines Infections caused by Rickettsiae, Gramnegative infections caused by Haemophilus. Infections due to Chlamydia trachomatis Antimicrobial A group of drugs that include anitprotazoals, antibiotics, antifungals, Diarrhea. Hypersensitivity reactions to sulfonamides and chemically related drugs,. Use in infants less than 2 years of age, use at term pregnancy. Hypersensitivity, use during tooth development stage(last trimester of pregnancy, neonatal period, during breastfeeding, and during childhood up to 8 years) Hypersensitivity, pregnancy, lactation, other azole products, some oral Page 31 N&V, diarrhea, abdominal pain, glossitis, stomatitis, anorexia, rhinitis, mental depression, seizures, insomnia, drowsiness, headaches, jaundice. Anorexia, N&V, diarrhea, glossitis, dysphagia, dizziness, headache sedation, hypersensitivity Sulfadiazine Trimethoprim N&V, diarrhea, dyspepsia, headache, dizziness, Tamiflu Macrobid Doxycycline Calcium Tetracycline hydrochloride Kylee Payne 2010 and antivirals. contraceptives. Antifungal Yeast infections, athletes foot, ring worm, UTIs, Decrease the incidence of candidiasis in clients undergoing a bone marrow transplant who receive cytotoxic chemotherapy or radiation therapy Hypersensitivity, lactation, Antiviral HIV infection Anti-neoplastics Hypersensitivity to drug. Some antineoplastics agents may be contraindicated for up to 4 weeks after radiation therapy or chemotherapy with similar drugs first trimester of pregnancy. Page 32 Headache, nausea, abdominal pain, diarrhea, skin rash, vomiting, dyspepsia, dizziness, N&V. Bone marrow depression, anorexia, diarrhea, stomatitis, rash, intestional ulcers, dizziness, headache, depression, confusion, dizziness, fatigue. Diflucan Miconazole Zanamivir Cidofovir Capecitabine Flutamide Kylee Payne 2010 PDRs Page 33 Kylee Payne 2010 Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Lopressor Beta-adrenergenic Blocker Dosage hypertension, chronic management of angina pectoris, stable symptomatic heart failure, acute MI MI in patients with HR less than 45 bpm, in 2nd or 3rd degree heart block, if SBP is less than 100 mm Hg C fatigue, dizziness, depression, shortness of breath, bradycardia, diarrhea Cimeetidine, Contraceptives (oral), Diphenhydramine, Hydroxychloroquine, Methimazole, Phenobarbitol, Quindine, Rifampin 25 mg, 50 mg, 100mg Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Pilocarpine Cholinergenic agonist Chronic simple glaucoma, Chronic angle-closure glaucoma, reverse mydriasis, pre/post op introcular tension inflammatory eye disease, acute-angle glaucoma, history of retinal detachment, ocular hypotension, asthma, epilepsy, C opthalmically: transient burning/stinging, tearing, blurred vision, headache. Orally: sweating, headache, nausea, chills Anticholinergenics, Beta blockers Opthalmic gel, 1/2 inch ribbon in lower conjunctival sac of affected eye(s) at bedtime, 5mg tid adjust based on response Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Atropine Anti-cholinergic Adjunt in peptic ulcer treastment, relieve pylorspasm, relax biliary and uretral colic and bronchiospasm Infants less than 3 months of age, primary glaucoma, adehesions between he iris and the lens C Dry mouth, urinary hesitation, headache, flushing, constipation, heartburn, N&V, blurred vision, stinging Not listed Adults- 0.3-1.2mg q 4-6 hours Page 34 Kylee Payne 2010 Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Carisoprodol Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Rozeram sedative hypnotic insomnia due to difficulty with sleep onset hypersensitivity to drug or any component of the product, use with severly impaired hepatic function, use with apnea C somnolence, sizziness, nausea, diarrhea, fatigue, headache, insomnia alcohol, azole antifungals, fluvoxamine, rifampin 8 mg taken 30 min before bed Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Dilantin Anti-epileptic Chronic Epilepsy, status epilepticus, cpntrol seizures during surgery, Paroxysmal choreothetosis, trigeminal neuralgia, Hypersensitivity to hydantois, exfoliative dermatitis, sinus bradycardia, second/third degree AV block, SA block, lactation C Ataxia, drowsiness, slurred speech, confusion, N & V, rash, consti[ation, diarrhea, gingival hyperplasia Acetaminophen, Alcohol (ethyl), Allopurinol, Amiodarone, Antacids, Anticoagulants (oral), Benzodiazepines, Charcoal, Adults, initial: 100mg 3 times a day, adjust at 7-10 day intervals until up to 300-400mg per day Skeletal muscle relaxant Treat skeletal muscle disorders- bursitis, low back disorders, muscle strains, contusions, fibrositis, spondylitis, sprains Acute intermittent porphyria, hypersensitivity to carisopradol or meprobamate, kids under 12 years of age C dizziness, drowsiness, N & V, headache, tachycardia Alcohol, Antidepressants, Barbiturates, Chlorcyclizine, CNS depressants, MAOI, Phenobarbital, Phenothiazines 350 mg 3-4 times per day Page 35 Kylee Payne 2010 Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Sinemet Antiparkinson drug Parkinsonism, Carbidopa is used alone in patients wjo require individual titration of carbidopa and levidopa History of melanoma, Lactation C Choreiform or dystonic movements, anorexia, N & V with or without abdominal pain, dry mouth, dysphagia, dysguesia, Use with tricyclic antidepressants initial 1 tablet of 10mg carbidopa/100 mg levadopa, 3-4 times per day, or 25mg carbidopa/100mg levidopa, tid Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Lyrica Anticonvulsant management of neuropathic pain, adjunctive therapy for adults with partial onset seizures, management of fibromyalgia Hypersensitivity to any component of the product, including lactose. Lactation C dizziness, somnolence, dry mouth, ataxia, periphreal adema, asthenia, abnormal gait, headache, confusion, amnesia Antidiabetic drugs, ehtanol, lorazepam, oxycodone, adults initial 50 mg tid may be increased to 300mg/day based on efficacy and tolerability Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Abilify Antipsychotic Acute and maintenance treatment of schizophrenia in adults and adolecents 13-17 yrs, Monotherapy for manic episodes Lactation, use with dimentia related psychosis, use of alcohol C Headache, agitation, insomnia, dyspepsia, constipation, N&V, drowsiness/ sedation/ somnolence Carbamazepine, Clarithromycin, Fluoxetine, Ketoconazole, Paroxetine, Quinidine, Initial,10-15mg a day for 2 weeks then up to 1-30mg/day use for periods up to six months Page 36 Kylee Payne 2010 Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Alprazolam Anti-anxiety drug Anxiety, anxiety associated with depression with or without agoraphobia use with itraconazole or ketoconazole, acute-narrow angle glaucoma D Drowsiness, ataxia, confusion Azole antifungal drugs, clarithomycin, erythromycin, portease inhibitors, SSRIs initial 0.25-0.5mg tid then titrate to the needs of the client at intervals of 3-4 days in at 1 mg/day. Not to exceed 4mg Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Adderall CNS stimulant ADHD treatment in kids over 3 years, narcolepsy in adults and kids 6 years and older Use in kids less than 3 years for ADD, use in kides under 6 years for narcolepsy, lactation C Decreased appetitie, upset stomach, insomnia, increased anxiety, irritability Not listed Adults and kids 12 years and older: 10mg/day increase in increments of 10mg until desired dosage Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Pamelor Antidepressant treatment of symptoms of depression, use in children C tachycardia, blurred vision, urinary retention, dry mouth, weight gain/loss, orthostatic hypotention Nortriptyline adults 25 mg 3-4 times per day begin at low dose and increase as needed Page 37 Kylee Payne 2010 Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Hydrocodone Analgesic Relief of moderate to moderately severe pain Hypersensitivity to acetaminophen or hydrocodone, lactation C N&V, urinary retention, lightheadedness, dizziness, sedation, mental clouding Anticholinergenics, CNS depressants, alcohol, MAOI, Tricyclic antidepressants For 2.5/500 product 1 or 2 q 4 hr up to 8 per day Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Capsaicin analgesic, topical (non opioid) Temporary relief of pain due to RA, and osteoarthritis, pain following herpes zoster, diabetic neuropathy for external use only Not listed burning, stinging Not listed Adults and kids over 2 years of age, apply to affected area 3-4 times daily. Not to exceed 4 Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Asprin Salicylate Pain from integumentary structures, gout, may be effective in less severe postop and postpartum pain Hypersensitivity,asthma, hay fever, nasal polyps, severe anemia, blood coagulation defects, pregnancy C Dyspepsia, N&V, epigastric discomfort, toxic effects are dose related ACE inhibitors, Aminosalicylate, Ammonium chloride, Anticoagulants, Ascorbic acid, Beta-blockers 3.2-6g/day in divided doses Page 38 Kylee Payne 2010 Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Allopurinol Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Celebrex NSAID Symptoms of osteoarthritis, and rheumatoid arthritis, juvenile rheumatoid arthritis, ankylosing spondylitis, acute pain use in severe hepatic impairment, those who have shown an allergic reaction to sulfonamides, asthma, urticaria C Abdominal pain/cramps, diarrhea, nuasea, dyspepsia/ indigestion, URTI ACE inhibitors, Antacids (Al and Mg containing) Asprin, Fluconazole, Furosemide, Thiazide diuretics, Warfarin Adults 100 mg twice a day or 200 mg once a day Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Cortaid Antipruritic Angioderma, uricartia, contact dermatitis, acne rosacea, psoriasis, pwemphigus, pruritus, herpetiformis Suspected infections, peptic ulcer psychoses, herpes simplex infections of the eye, cushing’s syndrome C Not listed Allopurinol, Aloe, Amphotericin B, Anethetics, Anticholinergic agents, Antidiabetic agents, norepinephrine Apply a thin film to affected area 2-3 times per day Antigout drug Management of clients with leukemia, lymphoma, and solid tumor malignancies in whom Chemo causes elevation of serum levels Hypersensitivity to drug, clients with idiopathic hemochromatosis or relatives of clients suffering from this condition, children C Rash, N & V, renal failure/insufficiency ACE inhibitors, AL salts, Ampicillin, Anticoagulants, Azathioprine, Chlorpropamide, Cyclosporine, Theophylline, Thiazide diuretics Tablets, 200-300 mg for mild to moderate gout, 400-600mg for moderate to severe tophaceous gout not to exceed 800 mg/day Page 39 Kylee Payne 2010 Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Lanoxin Cardiac Glycoside CHF, control of rapid ventricular contraction, slow HR in sinus tachycardia, SVT, cardiogenic shock ventricular fibrillation, tachycardia, in presence of digoxin toxicity, hypersensitivity to cardiac glycosides A Tachycardia, headaches, dizziness, diarrhea, mental disturbances, blurred vision, N & V, anorexia, yellow vision Albuterol, Aloe, Amiloride, Aminoglycosides, Aminosaliciyc Acid, Amphotericin B, Antacids, Beta blockers, buckthorn bark Adults, rapid 0.75-1.25 mg divided into two or more doses given at 6-8 hr intervals Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Verapamil Antiarrythmic Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Nitroglycerin Antianginal terminate an acute anginal attack due to CAD, prophylactically 10-15 min before activites that could cause an attack doasge not established in children C Headache (may be severe and persistant,) flushing, dizziness, weakness. Hypotension, parethesia not known Aerosol spray, lingual one to two metered doses (400-800 mcg) on or under the tongue q 5 min as needed Angina pectoris, with digitalis to control rapid ventricular rate, Essential hypertension, Atrial flutter or fibrillation Severe hypotension, 2nd or 3rd degree AV block, cardiogenic shock, severe CHF, sick sinus syndrome, C infection, flu-like symptoms, URTI, rhinitis, nausea, dyspepsia, diarrhea, constipation, headache, fatigue, dizziness Amiodarone, Antihypertensive agents, Antineoplastics, Atorvastatin, Barbiturates,Busiprone, Calcium salts, Carbamazepine 180mg in the a.m. with food, or 240mg q 12 hrs if needed Page 40 Kylee Payne 2010 Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Calan Calcium channel blocker Angina pectoris, with digitalis to control rapid ventricular rate, Essential hypertension, Atrial flutter or fibrillation Severe hypotension, 2nd or 3rd degree AV block, cardiogenic shock, severe CHF, sick sinus syndrome, C infection, flu-like symptoms, URTI, rhinitis, nausea, dyspepsia, diarrhea, constipation, headache, fatigue, dizziness Amiodarone, Antihypertensive agents, Antineoplastics, Atorvastatin, Barbiturates,Busiprone, Calcium salts, Carbamazepine 100mg, 120 mg, 180 mg, 200mg, 240 mg, 200 mg, 260 mg Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Catapres Antihypertensive Alone or with a diuretic to treat mild-moderate hypertension, treat spasticity, Epidurally, presence of injection site infection, clients on anticoagulant therapy, in bleeding diathesis, OB pain C Dry mouth, dizziness, srowsiness, sedation, constipation Alcohol, Beta blockers, CNS depressants, Levadopa, Local anisthetics, Mirtazapine, Prozasin, Narcotic analgesics, Initiial 0.1mg bid, then increase by 0.1mg-0.2 mg/ day until desired response is attained Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Furosemide Diuretic, loop Edema with CHF, nephrotic syndrome, hepatic cirrhosis, ascities, IV for acute pulmonary edema, PO for hypertension Never use with ethacrynic acid, anuria, hypersensitivity to drug, severe renal disease associated with azotemia and oliguria C Jaundice, tinnitus, hearing impairment, hypotension, water/electrolyte depletion, pancreatitis, abdominal pain, dizziness Charcoal, Clofibrate, Hydantoins, Popranolol Adults, 20-40 mg if respons eis adequate after 2 hr increase dose in 10 mg increments Page 41 Kylee Payne 2010 Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Coumadin Anticoagulant Prophylaxis of venous thrombosis, thromboembolic complications, pulmonary embolism Pregnancy, hemorrhagic tendancies or blood dyscrasias, recent or contemplative surgeries X Blleding/hemorrhage Acetaminophen, Allopurinol, Aminogluethimide,Aminoglycoside antibiotic, Amiodarone, Carbamazepine Adults initial 2-5mg per day, then adjust based on pronthrombin or INR derterminations Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Plavix Anti-platelet drug Non-ST-segment elevation acute coronary syndrome, to reduce the rate of death casued byand the rate of a comb. End point Lactation, active pathological bleeding such as peptic ulcer or intercranial hemorrhage. B Skin appendage disorders, headache, URTI, chest pain, flu-like symptoms Asprin, Atovastatin, Bupropion, Evening primrose oil, feverfew, garlic, ginger, ginko biloba, grapeseed extract 75mg, 300mg. Initial: 300mg loading dose then 75 mg once daily Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Lipitor Antihyperlipidemic Hypercholesterolemia, dysbetalipoproteinemia, clinically evident coronary heart disease, prevention of CV disease Active liver disease, unexplained persistantly high LFTs, Use with grapefuit juice. Pregnancy, lactation X Headache, asthenia, abdominal pain, cramps, infection, diarrhea, sinusitis, pharyngitis, myalgia, arthralgia, back pain, rash Antacids, Clarithromycin, Colestipol, Digoxin, Diltiazem, Erythtromycin, Nefazodone, Oral contreceptives, Protease inhibitors 10 mg, 20mg, 40mg, 80mg. Initial: 10-20mg daily then 10-80mg daily Page 42 Kylee Payne 2010 Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Accutane Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Zyrtec Antihistamine Relief of itching due to uricaria in adults and kids over 6 yrs of age, temporary relief of runny nose, sneezing, watery eyes Lactation, in those hypersensitive to hydroxyzine, use in children under the age of 4 years B Somnolence, dry mouth, fatigue, pharyngitis, dizziness Ritonavir One 10mg tablet daily or one 5 mg tablet twice daily Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Nolvadex Bronchdilator Coronary vasodilator Treatment of angina pectoris, prophylaxis of angina pectoris caused by CAD, with naldol to prevent variceal bleeding To abort acute anginal attacks C Dizziness, headache, hypotension, N & V, increased cough, allergic reaction Ethanol, Calcium channel blockers, Organic nitrates 20 mg bid 7 hrs apart treatment of axillary node negative, or node positive breast cancer, metastatic breast cancer, Lactation, Concomitant coumarin, anticoagulant therapy, women w/ history of pulmonary embolus D Flushing, hotflashes, altered/irregular periods, amenorrhea, vaginal discharge/bleeding, skin changes, fluid retention Anticoagulants, Bromocriptine, Cytotoxic drugs, Letrozole, Medroxyprogesterone, Rifamycins 10-20mg a day bid or 20 mg a day Page 43 Kylee Payne 2010 Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Prednisone Corticosteroid COPD, Opthalmopathy due to Gravevs disease, Duchenne's Muscular dystrophy Dose must be highly individualized C Insomnia, N&V, GI upset, fatigue, dizziness, muscle weakness, increased hunger/thirst, joint pain, decreased diabetic control Not shown Adults, 5-60mg/day in four equally divided doses after mealtimes and at bedtime. Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage dextromethorphan hydrobromide anti-tussive temporary relief of cough due to minor throat and bronchial irritation from the common cold or inhaled irritants persisitent or chronic cough or when cough is accompanied by excessive secretions, use during first tri of pregnancy C Drowsiness, dizziness, Gi disturbances, Grapefruit juice, MAOI, Quinidine, Silbutramine Gelcaps, Adults and kids over 12 yrs, 30mg/day q 6-8 hr Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Parvolex Expectorant Chronic emphysema, emphysema with bronchitis, chronic asthmatic bronchitis, tuberculosis, bronchiectasis Sensitivity to drug B Bronchial/tracheal irritation, N&V, rash, stomatitis Antibiotics 1-10mL of solution of 20?% solution 3-4 times per day Page 44 Kylee Payne 2010 Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Cimetidine Histamine – H2 Receptor Antagonists Short term and maintenance therapy for duodenal ulcers, Zollinger-ellison syndrome, UGI bleeding Kidsunder 12, lactation, cirrhosis, impaired liver/renal function B Headache, dizziness, diarrhea, gynecomastia, arthralgia Antacids, Anticholinergics, Benzodiazepines, Beta-blockers, chloroquine, Digoxin, Flecainide, Caffine 200mg as symptoms present up to two times per day Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Prevacid Proton Pump Inhibitor short term treatment for active duodenal ulcer, maintain healing of duodenal ulcer, eradicate infection in duod. Ulcer disease lactation, use with rabeprazole B diarrhea, N&V, constipation, rash Ampicillin, Clarithromycin, Digoxin, Fluvoxamine, Iron salts, Ketoconazole, Sucralfate Adults, short term use, 15 mg once daily before breakfast for 4 weeks Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Tums Antacid Hypocalcemia, antacid, nutritional supplements, Antihyperphosphatemic, Dosage not established in kids Not listed Headache, constipation, mild hypercalcemia, anorexia, N&V Omeprazole 0.5-1.5g as needed Page 45 Kylee Payne 2010 Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Meclizine Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Loperamide Antidiarrheals Control symptoms of diarrhea In clients with hwom constipation should be avoided, if body temp is over 101 degrees B Abdominal pain/distention, constipaqtion, dry mouth, N&V, epigastric distress, dizziness, drowsiness Ritanovir, Saquinavir 4 mg after first loose bowel movement, 2 mg after each subsequent bowel movement Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage beclomethasone hydrochloride Glucocorticoid Prevent recurrence of nasal polyps, relief of symptoms of seasonal and perennial allergic and nonallergic reactions, Status asthmaticus, acute episodes of asthma, hypersensitivity to drug or aerosol ingredients C Pharyngitis, Rhinitis, nasal congestion, sinusitis, coughing, viral infection None shown Antiemetic Prevention and treatment of N & V, Dizziness of motion sickness, Vertigo assoiciated with diseases of vestibular system use during lactation, use in kids under 12, use with caution in glaucoma, obstructive disease in GI or GU tract B Drowsiness, dry mouth, nervousness, constipation, insominia Not listed Adults, 25 mg to 50 mg approx. 1 hr before travel. May be repeated q 24 hr during travel Page 46 Kylee Payne 2010 Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Premarin Estrogen drug Moderato to severe vasomotor symptoms due to menopause, vuvlular or vaginal atrophy Use for prevention of cardiovascular disease due to increased risk of myocardial infarction X Abdominal/back pain asthenia, breast pain, infection, dyspepsia, nausea, arthralgia, pharyngitis, URTI None listed 10mg tid for 90 days Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Glucotrol Anti-diabetic Adjunct to diet for hyperglycemia in type 2 diabetes, Not listed C Hypoglycemia, headache, dizziness, hives, skin rash, jaundice Cimetidine Adults: 5 mg with breakfast Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Amoxil Penicillins ENT infections, genitak urinary infections, skin/skin structure infection, lower respiratory tract infection Use of the 875mg tablet in patients with a GFR of less than 30mL/min B N&V, hypersensitivity, gastritis, stomatitis None listed 250mg q 8 hrs Page 47 Kylee Payne 2010 Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Cefzil Cephalosporin Pharyngitis, tonsillitis, acute bacterial sinusitis, otitis media, uncomplicated skin and skin structure infections, Not known B N&V, diarrhea, abdominal pain, yeast infection of the mouth or vagina Not known Adults, 250mg, 500mg. 500mg q 24 hoursfor at least 10 days Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Gentamicin sulfate Aminoglycosides Serious infections of the conjunctiva or cornea, infections including neonatal sepsis, bacterial sepsis Ophthalmic use tot treat dendritic keratitis, vaccinia, varicella, fungal diseases of the eye, lactation C GI upset, diarrhea, anorexia, N&V, tinnitus, dizziness. Opthalmic: burning, irritation, itching, mydriasis Carbenicillin, Diuretics, Nephrotoxic drugs, Ticarcillin, 1mg/kg q 8 hrs up to 5mg/kg/day in life threatening infections Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Sulfadiazine Sulfonamides UTIs, Chanchroid, Inclusion conjunctivitis, Meningitis, Nocardosis, otitis media, Rheumatic fever In infants less than 2 months, pregnancy C Diarrhea, dizziness, headache, insomnia, rash, anorexia, stomach pain, tinnitus, myalgia Not listed 2-4 g a day in divided doses Page 48 Kylee Payne 2010 Name of Product Tetracycline hydrochloride Classification Tetracyclines Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Amphotericin Antibiotic/antifungal (Antimicrobial) Drug is toxic, mainly for use in patients with potentially fatal fungal infections, aspergillosis, cryptococcosis, zycomicosis Hypersensitiivty to drug unless condition is life threatening and amenable only to amphotericin B therapy, lactation B Hypotension, headache, epigastric pain, normocytic anemia, muscle/joint pain, tachypnea Aminoglycosides, Antineoplastic drugs, Azole antifungals, Corticosteroids, Corticotropin, Cyclosporine, Digitalis glycoside Initial, 0.25-0.3 mg over a period of 2-6 hours. Depending on client reaction dose may be increased gradually 5-10 mg/day Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Lamisil Antifungal Interdigital tinea pedis, tinea curis, tinea corporis, plantar tinea pedis, tinea versicolor, cutaneous candidiasis, Opthalmic or intravaginal use, PO use in chronic or active liver or renal disease or impairment B Headache, diarrhea, dyspepsia, rash, pruritis, nausea, taste disturbance Topical- irritation, itching, burning, dryness Beta bloockers, caffine, Cimetidine, Cyclosporine, Dextromethorphan, MAOI type B, Rifampin, SSRI, CYP2D6, Warfarin Cream, apply to affected and surrounding area twice a day for a week. Tablets 250mg/ day for 6-12 weeks Page 49 Kylee Payne 2010 Name of Product Classification Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Relenza Antiviral Prophylaxis and Treatment of influenza A and B in adults and kids 7 yrs and older Hypersensitivity to zanmivir or any component of the product, use in asthma or COPD C Dizziness, headache, cough, N&V, diarrhea, bronchitis, ENT infections, sinusitis None listed tablets, 10 mg once daily for 10 days Name of Product Classification Antineoplastic Uses Contraindications Pregnancy Side Effects Drug Interactions Dosage Page 50