HEALTH PARTNER SEARCH
7TH.
EU
FRAMEWORK
TECHNOLOGICAL
PROGRAMME
DEVELOPMENT
AND
RESEARCH,
FOR
DEMONSTRATION
(2007-2013)
PARTNER is looking for a Project
1.) CONTACT
Organisation
Victor Babes National Institute of
Pathology
Type of
RES
organisation (IND,
SME, RES, HE,
others)
Department
Pathology
Male/Female
F
Contact person
Camelia Doina VRABIE, MD, PhD,
Email
camianapat@yah
oo.com
Address
99-101 Splaiul Independentei, sect 5
Website
www.ivb.ro
Post code, city
050096, Bucharest
Country
Romania
Telephone
40 21 319 45 28
Are you familiar with the European Framework
X YES
□ NO
Programme?
Have you participated in a former European FP?
If yes please indicate the project or activity:
□ YES
x NO
PROJECT
Title
Acronym
□ Large
collaborative
Project type
project
Planned to
□ Small or medium
Collaborative
project
□ Network
of
Excellence
□ Other:
X partner
participate as
Call identifier
HEALTH.2010. 2.4.3-3: Molecular and physiological effects of lifestyle
factors on diabetes/obesity
Workprogramme
Your main
research
areas /
Description
of research
activities
Expertise /
Commitme
nt offered:
The research carried out in Victor Babes National Institute of Pathology, is focused
on integrated research in human pathology, cellular and molecular medicine,
genetics and immunology. The Pathology Department is involved in fundamental
research and clinical trials, mainly in tumor pathology, degenerative pathology,
specific and nonspecific inflammatory pathology. The research group is focused on
molecular and immunohistochemistry testing target therapy applying,
cytopathology, histopathology, in situ hybridization, QPCR and RT-PCR methods.
The researchers from the department are involved in many national projects of
research covering the almost entirely pathology.
V-B is certified ISO 9001 for biomedical research and the laboratories involved in
the project have national accreditations. The institute has conducted in the last 5
years over 100 national research projects and published a similar number of ISI
indexed papers. Patents regarding innovative therapy received international
awards. The institute has participated in several international projects: bilateral
cooperations (with Greece, Italy, France), NATO Science for Peace (No. 982838),
FP7 projects and International clinical trials. V-B joined several international
research networks, such as COST (Action TC: D39 Metallo-Drug Design and
Action) and EuroGentTest (Genetic Testing in Europe).
V-B partner can involve several research departments: Pathology, Biochemistry
and Proteomic Unit, Immunology and Genetics with multidisciplinary expertise
personnel (physicians, biochemists, biologists, bioinformaticians, biopysicists).
know-how / We are using multidisciplinary approach for pathology of the metabolic syndrome
(obesity) as: immunohistochemistry, molecular methods (manipulation of DNA,
expertise
RNA, classic polymerase chain reaction, Real Time PCR, revers transcription
PCR), microscopy and imaging techniques, and population recruitment and data
and
collection, clinical analysis and manipulation of biological samples (blood, tissues
fresh and archival). The department has already a strong collaboration with
equipment
surgery departments where the bariatric surgery is largely applied. The bariatric
you
surgery in Bucharest has a rich history already, and the main procedures used
(sleeve gastrectomy) led us to the new approaches on morbid obesity.
can provide
The institute can offer equipment for Proteomics (xMAP-array (LUMINEX),
Protein microarray, SELDI-TOF-MS, 2D-electrophoresis,
Chemiluminiscence/Fluorescence Multimode Reader, microelectrophoresis and
blotting systems) and Genomics domain (Gene microarray platforms, PCR/RTPCR, qPCR systems, DNA and RNA extractors, Experion system for nucleic acid
analysis, NanoDrop, pulsed-field gel electrophoresis system, DNA concentrator),
immunohistochemistry. The Imaging equipment that can be involved: Confocal
microscope, flow cytometers, Bio Station, transmission electron microscopes,
visible and fluorescence microscopes, motorized Imager microscope and in Situ
Imaging System.
We are interested in joining the EU network for discovering and linking novel
Keywords specifying
morbid
obesity, stomach
tissue, in
adipose
tissue,
liver
tissue,
targets andSporadic
pathways
with phenotype
and genotype
morbid
obesity
and,
to gain
the expertise:
bariatric
surgery,
ghrelin,
adipokines,
leptin,
previous
histopathology
insight into life-style factors and correlations between results of all the methods of
the tissues
(stomach,
liver,
adipose tissue)
registered at the time of
applied: selective
surgical
method,
histopathology
immunohistochemistry,
surgery
molecular and genetic analysis. Our network will establish the opportunity of the
bariatric surgery in people more younger aged.
Have you already
□ Yes
Have you already contacted
□ Yes
Identified Partners
other partners?
for projects you are
x No
x No
interested in?
Description
of the
I AGREE WITH THE PUBLICATION OF MY DATA