Biology 100 (CRN 26702) HUMAN BIOLOGY (3 credits) Course Syllabus and Tentative Schedule Spring 2008 Instructor. Bebi Davis. email:bebi@hawaii.edu, webpage: www2.hawaii.edu/~bebi Honolulu Community College is an Equal Opportunity/Affirmative Action Institution. If you have a disability and have not voluntarily disclosed the nature of your disability and the support you need, you are invited to contact the Disability Services, 845-9282, Building 2 -108A, for assistance. Lecture Wed - from 5:30 – 8:15 PM in Building 5-106 Consultation Wed - After class or by appointment The Purpose of Biology 100. Biology 100 is a human biology course that presents basic principles of human anatomy and physiology. It familiarizes the student with the principles of the living world, the basic form and function of the human body, and how these two relate to each other. The objective is to raise students' science literacy to enable them to understand scientific issues. Prerequisites. None Course competencies. These are listed in the HCC general catalog. Course Materials. Required text: "Human Biology" by Sylvia Mader, 10th ed. Course Structure. The course is composed of eight parts (See Page iii of text-book). You are required to understand and master the content in each part. The Instructor may suggest appropriate resources. You will be given three exams and a final exam. The final exam will cover the entire course with an emphasis on a few selected chapters. Grading. The grading scale will be based on the following: A (90-100%) B (80-89 %) C (70-79 %) Exam 1 – 100 points Exam 2 – 100 points Exam 3 – 100 points Final Exam - 100 points Total points possible - 400 points D (60-69 %) F (0 -60 %) March 23 is the last day for withdrawal from the course. After this date a W will be assigned only for a certified medical reason or for a death in the immediate family by the Dean of Students. A form requesting the incomplete grade can only be filed by students who are close to finishing the course with a passing grade. This is Departmental policy. Missing an exam can have serious consequences. Do not wait until after the exam is given to try to make up an exam. If you know that you have a scheduling conflict you must make arrangements with the Instructor prior to the exam. In the case of an unexpected illness or problem you must still notify the Instructor before the exam is given and be prepared to present a doctors note or similar evidence to provide a valid excuse. You might not receive full credit for a make up exam. Student Responsibility. The job of the Instructor is to provide the best possible presentation of the material that she can, and to provide the best learning environment that is possible. It is the student's responsibility to put forth the effort required to learn the material and to become competent with it. The Instructor will be happy to help you obtain these goals. The student should: 1. preview the lecture material before coming to class 2. attend every class and take notes for later review 3. bring the text to class to follow the lecture and check my webpage for postings. 4. do practice problems from the text until you are competent - the first step to learning is to find out what you don't know 5. make a list of what you don't understand and bring it to class and/or office hours 6. realize that this course will require a lot of study outside of class. Attendance: is critical for the understanding and success in this course. Also, listing, taking notes and collaborative work are important skills to help you succeed. It will be the student’s responsibility to obtain all information/assignments transmitted in each class meeting. I will not be absent except for a serious illness or emergency or unless I inform you in advance. If, on a regular class day, I do not arrive within fifteen (15) minutes of the class starting time you are dismissed. Two-way Communication Devices: These devices are not allowed in the classroom. Please see to it that these devices are turned off while in class. E-mail: For security reasons- I will only communicate to you through your hawaii.edu account. If you don’t normally check your “Hawaii.edu” account, you can easily forward your messages to the account that you frequently check (i.e. yahoo, roadrunner, aol, hotmail). Here is how to do it: 1. Go to <https://mail.hawaii.edu> 2. Log in with your UH username and password 3. Click on the Option Tab 4. On the left hand side select Settings 5. Go to Mail forwarding box and type the email address where you want your email to be sent 6. Click on Save Changes 6. Log Out By doing this, any email that I send to your “hawaii.edu” account will be automatically forwarded to the account that you check on a regular basis. In this way, you will not miss any important announcements from the UH system. week 1 W Jan 14 week 2 W Jan 21 week 3 W Jan 28 (online) week 4 W Feb 4 week 5 W Feb 11 week 6 W Feb 18 week 7 W Feb 25 week 8 W Mar 4 week 9 W Mar 11 week 10 W Mar 18 chapter 1, 2 TENTATIVE LECTURE SCHEDULE Topics Exploring Life and Science, Chemistry of Life 2 3 Chemistry of Life Cell Structure and Function 11 12 Skeletal System Muscular System 3 4 Cell Structure and Function Organization and Regulation of Body System 5 EXAM 1 Cardiovascular System: Heart and Blood Vessels 5 6 Cardiovascular System: Heart and Blood Vessels Cardiovascular System: Blood 7 8 Lymphatic System and Immunity Digestive System and Nutrition 9 10 Respiratory System Urinary System and Excretion - EXAM 2 13 14 Nervous System Senses week 11 (March 23 is the last day to withdraw) W Mar 25 SPRING BREAK week 12 W Apr 1 week 13 W Apr 8 week 14 W Apr 15 week 15 W Apr 22 week 16 W Apr 29 (online) 15 Endocrine System 18 19 Patterns of Chromosome Inheritance Cancer - EXAM 3 19 20 Cancer Patterns of Genetic Inheritance 16 17 Reproductive System Development and Aging week 17 W May 6 21 DNA Biology and Technology week 18 W May 13 FINAL EXAM (W (5/13) 5:30PM-7:15PM Students Learning Outcomes COURSE DESCRIPTION: An introduction to the structure and function of cells, tissues, organs, and organ systems of the body. In addition, there will be selected topics on nutrition, Infectious diseases and immunity, reproductive biology and modern genetic technology, and human genetics and genetic disorders. (3 credits) PERFORMANCE OBJECTIVES: Any student who successfully completes this course will be able to: Define the following terms: atoms, Ions, covalent bonds, hydrogen bonds, chemical formulas v. structural formulas, chemical names v. common names. Demonstrate the polymeric nature of macromolecules and identify the basic subunits of those polymers. Identify examples of representative carbohydrates, lipids, proteins, and nucleic acids. Also, define the three major differences between DNA and RNA and explain their involvement in protein synthesis. Define the functions of ATP and reduced NAD as sources of cellular energy. Demonstrate the function of enzymes within the cell. Illustrate the process of the aerobic respiration of glucose to demonstrate how one molecule of glucose can yield 38 ATPs worth of energy. Discuss the structure and functions of the cytoplasmic membrane of the cell: phospholipid bilayer, selective permeability, passive diffusion, facilitated diffusion, osmosis, and active transport. Describe the structure and function of the nucleus, cytoskeletal network, mitochondria, Golgi apparatus, lysosomes, different vacuoles, flagella, cilia, basal bodies, and centrioles. Differentiate between the 4 classes of tissues that make up the human body and describe the characteristics and properties of each class. Demonstrate the end results of Mitosis and Meiosis and discuss the importance of each process relative to the human body. Describe the various components of the male and female reproductive systems and how they function. Discuss the roles of hormones in the male and female reproductive systems and understand the female menstrual cycle in the context of 5 different hormones. Answer the following questions about the female reproductive system: What is the function of the female orgasm? Why does it take more time for a woman to reach orgasm (compared to a man)? Why does the human female lack an estrus cycle (unlike all other female mammals)? Differentiate between the various forms of STDs that afflict the human reproductive system. Describe the basic elements of Mendelian and post-Mendelian genetics and how they apply to human genetics, and apply the terms: homozygous dominant, homozygous recessive, heterozygous, Punnett Square, genotypic ratio, phenotypic ratio. monohybrid cross, and dihybrid cross. Describe human sex-linked disorders and explain why they are sex-linked. Identify human dominant and recessive genetic disorders. Discuss some recent aspects of Genetic Engineering including the cloning of genes and the potential cloning of humans. Identify the components of human skin and the various mucous and serous membranes of the body. Describe the generalized structure of bone and discuss the functions of the human skeletal system. Describe the generalized structure of a muscle and discuss how muscles contract. Compare and contrast the 3 different types of muscle and know where they are found. Become familiar with the structure and function of the organs of the digestive system. Compare the similarities and differences between arteries and veins. Describe the flow of blood through the four chambers of the heart, and the lungs and the rest of the body. Organize the 5 classes of leukocytes (wbcs) found in human blood and discuss the functions of each class. Also, define the lymphatic system of the body and discuss its importance in terms of function. Designate the functions of the First, Second and Third Lines of defense of the human body. List five examples of mechanical external barriers and five examples of chemical external barriers. Discuss the mechanism of the inflammatory response and compare the functions. Describe the B-system of immunity (humoral) of the body in terms of the definition of an antibody (Ab) and how the Abs are classified according their structural differences and their functional differences. Detail how Abs are produced by the body. Describe the T-system of Immunity (CMI) of the body. Detail how effector T-lympyhocites are produced by the body. Explain some of the major CMI activities of the body and how they protect you from different pathogens and cancers. Define the nature of allergic responses of the body and compare the Type I hypersensitivities with Type IV hypersensitivities. Also compare the differences between cutaneous localized anaphylaxis as opposed to generalized systemic anaphylaxis. Describe some examples of Type IV hypersensitivity responses. Compare the 4 different types of transplants or grafts into the human body and discuss the nature of ejection of transplanted tissues or organs. Discuss the graft v. host response. Describe the structure and functions of the organs of the respiratory system. Become familiar with some diseases of the respiratory system. Describe the structure and functions of the organs of the urinary system and detail the function of the individual nephron within a kidney. Compare the central nervous system to the peripheral nervous system. Compare the somatic nervous system to the autonomic nervous system. Compare the Sympathetic to the Parasympathetic nervous system. Discuss the structure and function of a neuron and a nerve. Describe the major components of the brain and what their functions are. Describe the control of the endocrine system of the body by the hypothalamus of the brain. Discuss the target tissues of various endocrine hormones and the responses of the target tissues. List some of the hormones produced by multifunctional organs of the body.