1 Angela Kempen February 16, 2012 Calculation Transmission Factor Table Extension Transmission Factor Calculation Objective: To determine the transmission factor for an Orfit carbon fiber table extension used during treatments with an Orfit mask. Purpose: When calculating dose to a patient, it is assumed that there is nothing in between the radiation source and the patient. When an object is introduced into the path of the beam, a certain amount of attenuation may occur. In order to deliver an accurate dose to the treatment volume, this attenuation must be taken into account. The data from this project was evaluated to measure and compare dosimetric changes produced when the Orfit table extension board is used. A patient under treatment for an area in head and neck region will commonly have a thermoplastic mask to aid in immobilization. In order to utilize the mask, a table extension is mounted onto the treatment couch. When treating with posterior fields, the beam will go through the extension. The attenuation of the table extension can be accounted for with the use of a transmission factor, included in the monitor unit dose calculation. Methods and Materials: To determine the transmission factor for the Orfit table extension, the data was measured on a Varian 21EX linear accelerator using 6 megavoltage (MV), 10 MV and 15 MV photon energies with a 10x10 field size at a 131.5 cm source-to-skin (SSD) distance. 200 monitor units (MU) were delivered at a dose rate of 600 MU per minute to a depth of 5 cm in water equivalent epoxy blocks. An Exradin A12 Farmer ionization chamber, with a 0.6cc collection volume, was placed at a 5 cm depth into a pre-cut hole within the epoxy blocks. The Farmer chamber was connected to a Keithley 616 electrometer to measure the charge. Two trials were done for each of the energies, including 6, 10 and 15MV to obtain reference beam data. Once reference data was recorded, the Orfit table extension was placed into the path of beam, and another two 2 trials were done for each photon beam energy. The Orfit table extension has a nominal thickness of 2.5cm. Image 1: Set-up of epoxy blocks with Farmer chamber and head extension Image 2: Data taken with a 616 electrometer for photon energies of 6MV, 10MV and 15MV Table extension attenuation 2/8/2012 Exradin Farmer Chamber --> 616 electrometer 5 deep in epoxy, phantom at 131.5SSD Table at 100 cm 10x10 field -8 6X open x10 C table in 10x open table IN 15x open Table In 2.065 2.07 2.015 2.015 2.19 2.19 2.15 2.145 2.265 2.265 2.23 2.23 Avg 2.0675 Attenuation amount of table 2.015 2.19 2.1475 2.265 2.23 5cm dp 6cm dp 0.962 0.937 5cm dp 6cm dp 0.978 0.958 Readings TMR 5cm dp 0.918 values 6cm dp 0.892 Attenuation of 1cm of tissue 0.026 Tissue equivalent thickness of table TF 0.975 0.025 TF 0.981 0.019 0.025 0.977 TF 0.985 0.015 0.02 0.776 0.773 Discussion: The transmission factor was found by taking a ratio of the reading with the table in / reading without the table. The transmission factor was 0.975 for the 6 MV photon energy, 0.981 for the 10 MV energy, and 0.985 for 15 MV energy. This data 3 represents attenuation of the beam by the table extension. It attenuates 2.5%, 1.9% and 1.5% for 6 MV, 10 MV and 15 MV photon beam energies respectively. A similar study was done at the Cleveland Clinic in Cleveland, OH, where it was found that the Orfit table extension did not significantly alter the dose distribution.1 They found 1.2% was the maximum attenuation of the Orfit board with a 6 MV photon beam energy.1 Clinical Application: The physicist was doing this project with me for his own application as well. He is incorporating the data into the Pinnacle treatment planning system. He evaluated the data, and calculated the tissue equivalent thickness of the table, in order to create a structure to include in dose calculations in the planning system. This information is not currently entered; therefore, I was unable to do a calculation with the treatment planning system. This data can be applied to an AP/PA treatment of the upper thoracic spine. The prescription is 300 centigray (cGy) per fraction for 10 daily treatments. The beams are weighted equally. The hand MU calculation for this treatment with and without the table extension is shown below. For the AP field, the transmission factor was not used since the table extension will not be in the path of the beam. For the PA field, the transmission factor indicates an increase in MU. This is reasonable since the beam is being attenuated; more monitor units are needed to give the same dose to the treatment volume. If the transmission factor were omitted from the dose calculation, there is risk of the treatment volume being under-dosed. 4 Image 3: Monitor Unit Calculations with and without the transmission factor 5 Image 4: Percentage of attenuation Conclusion: The transmission factor of the table extension demonstrates that attenuation occurs and will have an impact on treatment delivery and the dose received at the target volume. The table extension does not however have a large clinical impact on the dosimetry because it usually impacts multiple field intensity modulated radiation therapy 6 (IMRT) head and neck treatments. IMRT will likely only utilize one or two beams at most that will be delivered through the table extension; therefore, the 2.5% attenuation of the extension would be less by a factor corresponding to the number of beams used. A patient dose distribution takes into account several different corrections, and the magnitude of the correction is different for each type, although beam modifying corrections are the most important.2 Only a small amount of the beam dose may be penetrating through the extension, but with the precision in today’s world of radiation oncology, this needs to be accounted for. 7 REFERENCE: 1. Gajdos S, Muhieddine L, Chan G, Weinhous M. A Dosimetric Comparison of Three Commercially Available Carbon Fiber Table Extension Boards. Med Phys. 2005;32(6):1. doi:10.1118/1.1997731. 2. Khan F. Treatment Planning in Radiation Oncology. 2nd ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2007.