Supplementary Table 1(a): Predictors of patient mortality by transplant type; hazard ratios,
95% confidence intervals and p-values corresponding to plotted values in the forest plot
(Figure 4).
LDLT
DDLT
HR (95% CI)
p-value
HR (95% CI)
p-value
Female vs. male
0.68 (0.48-0.95)
0.02
0.89 (0.62-1.29)
0.54
Hispanic vs. non-Hispanic
1.22 (0.80-1.85)
0.36
0.64 (0.39-1.06)
0.08
Recipient diagnosis: HCC
1.46 (0.97-2.18)
0.07
0.97 (0.61-1.55)
0.90
Recipient diagnosis:
malignancy other than HCC
1.62 (0.69-3.76)
0.26
3.36 (1.20-9.40)
0.02
Recipient diagnosis: PSC
0.57 (0.33-0.98)
0.04
0.36 (0.18-0.73)
0.005
On dialysis at transplant
4.47 (1.44-13.89)
0.010
3.47 (1.80-6.71)
<.001
Recipient age at transplant
(per 10 years), < 55
1.17 (0.93-1.49)
0.19
1.19 (0.90-1.57)
0.23
Recipient age at transplant
(per 10 years), > 55
1.60 (1.11-2.30)
0.01
1.67 (1.11-2.50)
0.01
Donor age > 50 vs. < 50
1.62 (1.08-2.43)
0.02
1.43 (1.00-2.04)
0.05
MELD at transplant (per 5
points)
1.10 (0.96-1.27)
0.18
1.06 (0.95-1.19)
0.29
Supplementary Table 1(b): Predictors of graft failure by transplant type; hazard ratios, 95%
confidence intervals and p-values corresponding to plotted values in the forest plot (Figure
4).
LDLT
DDLT
HR (95% CI)
p-value
HR (95% CI)
p-value
Female vs. male
0.69 (0.52-0.93)
0.02
1.02 (0.73-1.41)
0.92
Hispanic vs. non-Hispanic
1.04 (0.71-1.52)
0.85
0.57 (0.36-0.91)
0.02
Recipient diagnosis:
autoimmune hepatitis
0.58 (0.28-1.20)
0.14
0.29 (0.09-0.94)
0.04
Recipient diagnosis: HCC
1.41 (0.98-2.03)
0.07
1.08 (0.70-1.66)
0.72
Recipient diagnosis: PSC
0.74 (0.48-1.13)
0.16
0.45 (0.25-0.81)
0.008
On dialysis at transplant
2.15 (0.71-6.54)
0.18
2.94 (1.58-5.46)
<.001
Recipient age at transplant
(per 10 years), < 55
1.02 (0.84-1.23)
0.84
0.94 (0.73-1.19)
0.59
Recipient age at transplant
(per 10 years), > 55
1.40 (1.00-1.96)
0.05
1.52 (1.03-2.23)
0.03
Donor age (per 10 years)
1.57 (1.10-2.23)
0.01
1.51 (1.09-2.09)
0.01
MELD at transplant
1.12 (0.99-1.26)
0.07
1.06 (0.95-1.18)
0.29
DDLT=deceased donor liver transplant; LDLT=living donor liver transplant; HCC=hepatocellular
carcinoma; PSC=primary sclerosing cholangitis; MELD=model for end-stage liver disease;
Supplementary Table 2(a): Additional variables tested in mortality Cox model*
Hazard Ratio
95% Lower
Confidence
Limit for
Hazard Ratio
95% Upper
Confidence
Limit for
Hazard Ratio
p-value
0.99
0.95
1.04
0.66
2004-2009
0.98
0.69
1.40
0.92
2010-2014
0.94
0.58
1.52
0.81
2004-2009
0.86
0.59
1.25
0.44
2010-2014
1.11
0.63
1.98
0.71
Time on waitlist (years)**
1.03
0.95
1.11
0.49
Left lobe vs. right lobe
0.87
0.38
2.01
0.75
Year of transplant
Era of transplant (Ref =
1998-2003)
Era of transplant (Ref =
1998-2003, restricted to
continuing centers)
* Each variable was tested individually adjusted for the covariates in the final model for patient
survival,
among LDLT recipients only.
** US centers only, includes DDLT
Supplementary Table 2(b): Additional variables tested in graft failure Cox model*
95% Lower
Confidence
Limit for
Hazard Ratio
95% Upper
Confidence
Limit for
Hazard Ratio
p-value
0.98
0.94
1.01
0.23
2004-2009
0.94
0.67
1.28
0.68
2010-2014
0.81
0.54
1.22
0.32
2004-2009
0.88
0.63
1.23
0.46
2010-2014
1.07
0.65
1.74
0.80
Time on waitlist (years)**
1.00
0.94
1.07
0.95
Left lobe vs. right lobe
0.87
0.44
1.71
0.69
Hazard Ratio
Year of transplant
Era of transplant (Ref =
1998-2003)
Era of transplant (Ref =
1998-2003, restricted to
continuing centers)
* Each variable was tested individually adjusted for the covariates in the final model for graft
survival,
among LDLT recipients only.
** US centers only, includes DDLT