Ocular Tumors The most common melanocytic tumor 1st – 2nd decade Junctional, Compound or subepithelial Limbal, at plica or caruncle Signs of malignant transformation Treatment: excision Epithelial melanosis Dark skinned, bilateral Flat, brown, limbal Melanocytoma Rare, congenital Black Cannot be moved freely over the globe Papilloma HPV Fibro-vascular core, stratified squamous non-keratinized epithelium Sessile or pedunculated Treatment: excision + MMC or cryotherapy to the base Haemangioma Sturge Weber syndrome Pyogenic granuloma Dermoid Choristoma Collagen wall, lined by stratified squamous epithelium, containing dermal elements Limbal Associations: Goldenhar, nevus sebaceous of Jadassohn Complications: astigmatism, dellen, irritation Treatment: excision ± lamellar kerato-sclerectomy Primary Acquired Melanosis "PAM" Malignant & pre-malignant Epi-bulbar tumors Benign Epi-bulbar Tumors Nevus Unilateral, old age, faire complexion With atypia OR without atypia Uni- or multi-focal Dark brown Bulbar, palpebral Signs of malignant transformation Treatment: Excision with safety margin + MMC or cryotherapy to the base Melanoma Ocular surface squamous neoplasia "OSSN" Lymphoproliferativ e lesions Fibro-vascular granulation tissue Following trauma, surgery Pink, fleshy, fast growing Treatment: topical steroids ± excision Kaposi sarcoma De novo or after PAM, papilloma Melanotic or Amelanotic Fixed to sclera Treatment: Excision with safety margin + MMC or cryotherapy to the base Poor prognostic factors Risk factors: UVR, HPV, AIDS Epithelial dysplasia or CIN or SCC Interpalpebral; at limbus Gelatinous mass OR leukoplakia OR papillomatous Treatment: Excision with safety margin + MMC or cryotherapy to the base Reactive lymphoid hyperplasia De novo, extension from orbit or part of systemic lymphoma Salmon pink infiltrate Treatment: radiotherapy, chemotherapy, excision, cryotherapy AIDS Spindle shaped cells, vascular channels, inflammatory cells DDx: subconjunctival hemorrhage Treatment: radiotherapy, excision ± cryotherapy Dermolipoma Similar to dermoid + fatty tissue Soft, movable, upper temporal DDx: prolapsed orbital fat, orbital lobe of lacrimal gland Treatment: debulking NB: excision cause scarring