Name ___________________________________________ date _______________ per _____________ Monster Genetics You must complete the following pre learning in order to prepare to build your monster. Monster Genetics Pre Learning: Read the following information, complete the Punnett squares, and answer the questions. Pre lab MUST be completed BEFORE beginning the Monster Genetic Lab. Important vocabulary: Phenotype Genotype Dominant Recessive Allele Gene Trait P generation F1 generation F2 generation Chromosome Punnett square Homologous Chromosome Mendelian Inheritance – Simple Dominant, Simple Recessive, & the Rule of Dominance Simple dominance is an inheritance pattern where the dominant allele (noted as a capital letter) always trumps the recessive allele when present. For example: T = the dominant allele for tall plant and t = the recessive allele for a short plant. 1. Plants with the genotypes TT or Tt will be ________________. 2. How many dominant alleles are needed for the dominant phenotype to be expressed (seen). ___ The only time the recessive phenotype is expressed is in the homozygous recessive genotype. 3. Plants with the genotype tt will be _________________. In humans, polydactyly (having extra fingers or toes) follows a simple dominance inheritance pattern. Polydactyly is actually the dominant trait, but there is a low frequency of the dominant allele in the population. Create a Punnett square for a man who is heterozygous for Polydactyly and a woman who has normal numbers of fingers and toes. P = Polydactly P = normal number of fingers & toes Simple Dominance, used when referring to the dominant trait, and Simple Recessive, used when referring to the recessive trait, are both considered Mendelian Inheritance because they follow the Rule of Dominance described by Mendel. Incomplete Dominance Inheritance Incomplete Dominance occurs when the heterozygote phenotype is a blending of the dominant and recessive phenotypes. Neither the dominant nor the recessive phenotypes are expressed (shown) but rather an intermediate or blended phenotype is expressed in the heterozygous. Incomplete Dominance Inheritance has a special genotype notation that uses a capital letter for the dominant allele and the same capital letter with an accent mark (‘) for the recessive allele. For example: a homozygous dominant plant TT = Tall homozygous recessive plant T’T’ = short 4. In Incomplete Dominance Inheritance the heterozygous plant TT’ would be ________height. The color of a particular species of mouse is inherited through Incomplete Dominance Inheritance. A homozygous dominant Black mouse is crossed with a homozygous recessive white mouse. 5. What is the genotype of the Black mouse? ______________ 6. What is the genotype of the White mouse? ______________ (remember the special notation for Incomplete Dominant Inheritance) 7. Complete the Punnett square for a cross between the Black mouse and the White mouse. 8. What color will the F1 generation be? _____________ 9. What is the genotype of the F1 generation? ________ In humans, the trait for sickle cell anemia is incompletely dominant. A person who is heterozygous for the sickle cell trait has less severe anemic symptoms than the homozygous recessive person. Sickle cell heterozygotes are also resistant to malaria. Co-dominant Inheritance Co-dominant Inheritance is when both alleles are dominant, neither one is recessive to the other. The heterozygote expresses (shows) both phenotypes equally. In the case of Co-dominant Inheritance each allele is noted using a different capital letter. For example: Red=RR Black=BB Red with black stripes=RB A chicken with all black feathers BB mated with a chicken with all white feathers WW the offspring are referred to as checkered chickens because they have both black feathers and white feathers. (see picture on right) 10. Complete a Punnett square showing a cross between two checkered chickens (chickens with both black and white) in the F1 generation in the picture to the right. 11. What is the probability (% chance) of producing: White chickens in the F2 generations? ________ Black chickens in the F2 generation? ________ Checkered chickens in the F2 generation? ________ In humans blood type is inherited co-dominantly. A mother with type A blood has blood cells with the A protein on them. A father with type B blood has blood cells with the B protein on them. Their child with AB type blood has blood cells that have both the A and the B protein on them. Sex-linked Inheritance Sex-linked Inheritance refers to the genes that are carried on the sex chromosomes. Females are XX and males are XY. In females the sex chromosomes are homologous chromosomes, composed of the same genes in the same order. In males the sex chromosomes are NOT homologues chromosomes, the X and Y chromosomes are NOT homologous chromosomes; the genes found on the Y chromosomes are different from the genes found on the X chromosome. The X chromosome is much larger than the Y chromosome, and contains more genes than the Y, for this reason, most sex-linked traits are due to genes found on the X chromosome. The notation for Sex-linked Inheritance includes the sex chromosome, for example: XR = normal red/green vision which is dominant Xr = red/green color blindness which is recessive 12. If “which is dominant” and “which is recessive” was NOT written above, how would you have known that red/green color blindness is recessive? 13. A girl with the genotype XR Xr has what type of vision? _______________________________ 14. A boy with the genotype XR Y has what type of vision? ________________________________ 15. If the boy above had inherited the recessive allele from his mother his genotype would be _____ a. His phenotype would be? ________________________________ Explanation: Girls who inherit the gene for red/green colorblindness from their mothers Xr still have a chance to inherit the dominant, normal gene from their father XR . A girl who is heterozygous for a recessive Sexlinked trait is said to be a carrier. Boys who inherit the gene for colorblindness Xr from their mothers don’t get that second chance because the Y chromosome they inherit from their fathers does not contain any gene for color vision, normal or not. After reading the explanation, go back and check your answers for numbers 12 – 15a, make corrections if you need too. 16. Why are more sex linked recessive traits seen in males? Complete the following for practice: Snap dragons (flowers) are incompletely dominant for color; they have phenotypes red, pink, or white. The red flowers are homozygous dominant, the white flowers are homozygous recessive, and the pink flowers are heterozygous. Give the genotypes for each of the phenotypes using R and R’ Red snapdragon genotype _________ pink snapdragon _________ white snap dragon _________ Show genetic cross between a pink snap dragon and a red snap dragon. __________ x __________ Will any white snapdragons be produced? _________ How do you know your answer is correct? In Smileys, eye shape can be Starred = SS, Circular = CC, or a Circle with a Star = CS What type of inheritance is demonstrated in the eye shape of these smileys? ___________________________ Write the genotypes for the pictured phenotypes below. Genotypes: ________ _________ _________ Show the cross between a star-eyed and a circle eyed _________ x _________. What are the phenotypes of the offspring? _____________________ What are the genotypes? ____________________ Show a cross between a circle star eye and a star eye ________ x _________ How many of the offspring are circle eyed? _________ How many of the offspring are circle-star eyed? _____________ Sex-linked Inheritance In fruit flies, eye color is a sex linked trait. Red is dominant to white. 1. What are the sexes and eye colors of flies with the following genotypes: X R X r _________________ X R Y _________________ X R X R _________________ X r Y _________________ 2. What are the genotypes of these flies: white eyed, male ____________ red eyed female (heterozygous) ________ white eyed, female ___________ red eyed, male ___________ 3. Show the cross of a white eyed female X r X r with a red-eyed male X R Y .