Ergogenic Effects of Glycerol HKIN 262: Performance-Enhancing Substances Professor: Dr. Daniel Kane Friday, December 2nd, 2011 Stephen MacLeod (200902441) Ergogenic Effects of Glycerol There are a wide variety of supplements that can either result in an increase or decrease in ergogenic effects in humans. Some may react differently to certain substances then other people. Glycerol is a three-carbon molecule, which is similar to alcohol. “It occurs naturally in the human body as a component of stored fat; a small amount is also present in body fluids as free glycerol. When ingested, it is absorbed and increases the concentration of the fluid in the blood and tissues” (Robergs, R.A., 1998). This metabolite historically shows to be a safe and effective hyperhydrating agent that may be beneficial to the performance of athletes (1). In this paper, I will elaborate on two studies that analyzed the ergogenic effects glycerol has on athletic performance in tennis and mountain biking. The first study was performed at the School of Human Performance and Recreation of the University of Southern Mississippi. The purpose of this study was to compare glycerol and water hyperhydration on tennis related skill and agility performance. This experiment consisted of eleven male subjects that had to complete two counter-balanced, double blind trials. The trials all consisted of three important phases. In the first phase, the subject would begin with a hyperhydration phase. The hyperhydration either contained 1.0 g*kg -1 glycerol or none at all. The second step was the exercise process. This consisted of 120 minutes of playing tennis, which is known as an exercise-induced dehydration (EID). Finally, in the last phase, the subjects are rehydrated with or without the glycerol sample included. This phase takes place during the 90 minutes after the exercise was performed. (Wingo et al., 2004) The eleven advanced level male tennis players that volunteered had an average age of 27 years old, an average body weight of 77.4 kg, and an average body fat of 12.3%. Before being tested, each subject completed a health history questionnaire, had their blood pressure measured, and many other health and physicality tests. Performances such as speed, agility, and serves. The performance was evaluated by different technologies for each test. The tests were performed three times each to collect more accurate data. (Wingo et al., 2004) After all tests and information were analyzed, the results showed some positive and negative effects. During and after the experiments, none of the subjects experienced any nausea or vomiting. The study showed that the subjects who were given samples containing glycerol improved hydration status as well as expand their plasma levels. This shows that water-containing glycerol can make you more hydrated then water on its own. Although hydration is increased with the consumption of glycerol, the performance evaluation had different results. Results show that “tennis-related agility and skill performance was not affected”(Wingo et al., 2004) by the glycerol. It was also demonstrated that just a small amount of hypohydration negatively influences anaerobic performance by less then 3%. Therefore, in this case, this substance shows ergolytic effects on athletic performance. (Wingo et al., 2004) In the second case I will be reviewing, the subjects are required to race mountain bikes in a high heat area. This case had 12 subjects who took part in 3 treatments. These treatments outlined what the sample contained and when it is consumed. In the first treatment, water was consumed before the race and no water during the race. This is called a no water during exercise (NE) treatment. The second treatment (G) is a mixture of glycerol and water prior to the race and was allowed to consume water during exercise. The third treatment (W) was simply consuming water before and during the race. (Magal et al., 2003) The objective of this case was “to determine if pre-exercise hydration with and without glycerol differentially affects physiologic and performance responses during mountain-bike races in the heat”. (Magal et al., 2003) Each subject was responsible for completing numerous measurements and an Environmental Symptoms Questionnaire. The subjects had an average age of 24.5 years old, an average body fat percentage of 14.3, an average mass of 76.9 kg, and an average height of 179 cm. (Magal et al., 2003) In the study itself, the subjects (who are all experienced mountain bikers) had to race around three 10-mile (16 km) loops of rough terrain. Each was allowed to rest for eight minutes after each loop so that the data could be collected for each stage. Each of the three treatments described above were flavored with sugar-less powder that would mask any potential taste or texture of glycerol. Once the professionals working on this experiment analyzed all the information, similar information to the first case was found. (Magal et al., 2003) Results show that after the exercise was performed, the G treatment subjects were not as thirsty as the subjects who received the NE and W treatments. This shows, just as we seen in the first case, that water containing glycerol appears to increase hydration more then the water itself. Again, just like the first case, because of water retention, the plasma volumes were expanded. Although the G trial performed 5 minutes faster on loop three than the W and NE trials, it is not significant enough to show much improvement. The final conclusion of this case showed that glycerol mixed with water before an intense mountain bike race in high heats did not show any increase in ergogenic effects. (Magal et al., 2003) Prior to reading these two articles, from what I already knew about glycerol, I suspected there to be some ergogenic effects due to the fact that it increased the subjects hydration. These case studies prove that although it may increase hydration and expand plasma volumes, glycerol does not improve athletic performance. In fact, as I stated earlier, in some cases, the substance may be slightly ergolytic. This shows that with the information provided, we can state that glycerol is probable to not provide any ergogenic effects. Bibliography Magal, M., Webster, M., Sistrunk, L., Whitehead, M., Evans, R., Boyd, J., 2003. Comparison of Glycerol and Water Hydration Regimens on Tennis-Related Performance. Pp. 150-156. Wingo, J., Casa, D., Berger, E., Dellis, W., Knight, J., McClung, J., 2004. Influence of a Pre-Exercise Glycerol Hydration Beverage on Performance and Physiologic Function During Mountain-Bike Races in the Heat. Pp. 169-175. Robergs, 2011) CITETHIS SHITTTTTTTTTTT