FLORIDA STATE COLLEGE AT JACKSONVILLE COLLEGE CREDIT COURSE OUTLINE COURSE NUMBER: PCB 3513C COURSE TITLE: Genetics and Molecular Biology PREREQUISITE(S): BSC 2011C (Principles of Biology II with lab) with a grade of “C” or better and CHM 2046C (General Chemistry and Qualitative Analysis II with lab) with a grade of “C” or better COREQUISITE(S): None CREDIT HOURS: 4 CONTACT HOURS/WEEK: 6 CONTACT HOUR BREAKDOWN: Lecture/Discussion: 3 Laboratory: 3 Other __________: FACULTY WORKLOAD POINTS: 5.1 STANDARDIZED CLASS SIZE ALLOCATION: 27 (laboratory safety considerations) CATALOG COURSE DESCRIPTION: This course is designed for biomedical sciences or other natural sciences majors and will cover the study of the principles of heredity including the gene concept, Mendelian and non-Mendelian inheritance, molecular and population genetics. Topics will include the nature, organization, transmission, expression, recombination and function of genetic materials. Principles are derived for genetically characterizing populations. The curriculum is inquiry based and fully integrated with laboratory experiences that emphasize active learning strategies. SUGGESTED TEXT(S): Klug, et al, Concepts of Genetics, Benjamin Cummings publishers, Latest edition Brooker, Genetics Concepts and Principles, McGraw-Hill publishers, Latest edition Pierce, Genetics: A Conceptual Approach, W.H. Freeman Publishers, Latest edition Elrod and Stansfield, Genetics, Schaum’s Outlines, Latest edition 1 SUGGESTED TEXT(S) (continued): Mertens, et al, Genetics Laboratory Investigations, Prentice Hall, Latest edition IMPLEMENTATION DATE: Fall term 2011 (20121) – Proposal 2010-25 REVIEW OR MODIFICATION DATE: Fall Term 2015 (20161) – Outline Review 14-15 2 COURSE TOPICS CONTACT HOURS PER TOPIC I. Overview of genetics 3 II. Mendelian inheritance 6 A. B. C. III. DNA and RNA A. B. C. IV. Mitosis and meiosis Linkage and gene mapping Non-Mendelian inheritance 6 Molecular structures Chromosome structures DNA replication Processes of RNA and DNA A. B. C. D. 10 Gene transcription mRNA translation Gene regulation Gene mutation V. DNA technology and its applications 10 VI. Practical uses of Genetics 10 A. B. C. Medical genetics Population genetics Evolutionary genetics Total lecture hours: 45 3 LABORATORY TOPICS (suggested completion 15 out of 20 lab modules; for a semester total of 45) COURSE TOPICS (continued) CONTACT HOURS PER TOPIC VII. Background in Molecular and Mendelian genetics A. B. C. D. E. VIII. DNA and RNA structure and function Mitosis and meiosis Dominant and recessive genes Gene interactions Basic probability 12 (2) (2) (2) (3) (3) Statistics A. B. C. 6 Mutually exclusive events Probability and pedigrees Chi square test (2) (2) (2) IX. Genetics of Drosophila melanogaster 3 X. Genetics of Zea mays 3 XI. Genetics of E. coli 3 XII. Human chromosomes 3 XIII. Techniques in Molecular genetics 10 A. B. C. XIV. Isolation of DNA Restriction Endonuclease Digestion and Gel Electrophoresis of DNA Amplification of DNA polymorphisms by PCR and DNA fingerprinting (3) (4) (3) Population genetics A. B. 5 The Hardy-Weinberg principle The effects of selection and genetic drift Total laboratory hours: (3) (2) 45 4 Florida State College at Jacksonville Course Learning Outcomes and Assessment SECTION 1 Semester Credit Hours (Credit): Contact Hours (Workforce) Course Prefix and Number: PCB 3513C Course Title: Genetics and Molecular Biology 4 SECTION 2a (To be completed for General Education courses only.) TYPE OF COURSE (Place an “X” in the box next to those that are applicable.) General Education Core (If selected, core discipline area will be identified in Section 4.) General Education (If selected, you must also complete Section 4, Section 5, and Section 8) SECTION 2b TYPE OF COURSE (Place an “X” in the box next to those that are applicable.) A.A. Elective A.S. Required Course A.S. Professional Elective A.A.S. Required Course A.A.S. Professional Elective Technical Certificate X PSAV/Clock Hour/Workforce Upper Division/Bachelors Development Education Apprenticeship Other: If selected, use this space to title “other” option. SECTION 3 INTELLECTUAL COMPETENCIES (Place an “X” in the box next to those that are applicable.) Reading Speaking Writing Listening X Critical Analysis Qualitative Skills Information Literacy Ethical Judgement X Scientific Method of Inquiry Working Collaboratively SECTION 4 (To be completed for General Education courses only.) GENERAL EDUCATION DISCIPLINE AREA (Place an “X” in the box next to those that are applicable.) Communications Humanities Mathematics Social and Behavioral Sciences Natural Sciences SECTION 5 (To be completed for General Education courses only.) GENERAL EDUCATION LEARNING OUTCOME AREA (Place an “X” in the box next to those that are applicable.) Communication Critical Thinking Information Literacy Scientific and Quantitative Reasoning Global Sociocultural Responsibility SECTION 6 LEARNING OUTCOMES TYPE OF OUTCOME (General Education, Course or Program) Demonstrate knowledge of the molecular structure and functions of DNA and RNA. Course Demonstrate knowledge of both Mendelian and non-Mendelian inheritance. Course METHOD OF ASSESSMENT Methods of assessment can include exams, quizzes, papers, lab reports and/or oral presentations Methods of assessment can include exams, quizzes, papers, lab reports and/or oral presentations 5 SECTION 6 (Continued) LEARNING OUTCOMES Demonstrate knowledge of the processes of DNA replication, gene transcription, mRNA translation and gene regulation. TYPE OF OUTCOME (General Education, Course or Program) Course Demonstrate technical and analytical laboratory skills as they apply to biomedical science research and/or applications. Program Demonstrate the application of interdisciplinary natural science curricula to biomedical sciences. Program Conduct an experiment, collect and analyze data, and interpret results in a laboratory setting Discipline Analyze, evaluate, and test a scientific hypothesis Discipline Use basic scientific language and processes and be able to distinguish between scientific and non-scientific explanations Discipline Identify unifying principles and repeatable patterns in nature, the values of natural diversity, and apply them to problems or issues of a scientific nature Discipline Analyze and discuss the impact of scientific discovery on human thought and behavior Discipline METHOD OF ASSESSMENT Methods of assessment can include exams, quizzes, papers, lab reports and/or oral presentations Methods of assessment can include exams, quizzes, papers, lab reports and/or oral presentations. Students will answer a set of questions developed by the program faculty and delivered across courses in the discipline. A faculty panel will evaluate the answers a common rubric with scores from 1 (not yet competent) to 3 (competent). Students will answer a set of questions developed by the program faculty and delivered across courses in the discipline. A faculty panel will evaluate the answers a common rubric with scores from 1 (not yet competent) to 3 (competent). Students will answer a set of questions developed by the program faculty and delivered across courses in the discipline. A faculty panel will evaluate the answers a common rubric with scores from 1 (not yet competent) to 3 (competent). Students will answer a set of questions developed by the program faculty and delivered across courses in the discipline. A faculty panel will evaluate the answers a common rubric with scores from 1 (not yet competent) to 3 (competent). Students will answer a set of questions developed by the program faculty and delivered across courses in the discipline. A faculty panel will evaluate the answers a common rubric with scores from 1 (not yet competent) to 3 (competent). Students will answer a set of questions developed by the program faculty and delivered across courses in the discipline. A faculty panel will evaluate the answers a common rubric with scores from 1 (not yet competent) to 3 (competent). SECTION 7 Faculty name(s): Dianne M. Fair Date: 12/17/2010 CS20150615 6