Lavigna, Robin. Magnesium. KNH 413 – Medical Nutrition Therapy II. Miami University, Oxford, Ohio, Spring 2013. Magnesium 1. What is the nutrient? Magnesium 2. What is the RDA/DRI for the nutrient? 3. How is the nutrient metabolized? It is mostly absorbed in the upper small intestine, 50% of dietary magnesium is absorbed in a normal person. Absorption of magnesium requires an acidic stomach. It is secreted by the kidneys. 4. What are food sources of the nutrient? Dark green vegetables such as spinach, some legumes, nuts and seeds, and whole unrefined grains (with bran), and even “hard” water are good sources of magnesium. Some examples of foods include: wheat bran almonds, spinach, cashews, soy beans, mixed nuts, oatmeal, shredded wheat, peanuts and peanut butter, potato, rice, pinto beans, lentils, banana, yogurt, and halibut. 5. What disease states alter the nutrients metabolism? Gastrointestinal disorders that impair absorption such as Crohn’s disease alter the metabolism of magnesium. Chronic or excessive vomiting and diarrhea can also alter the state. Addison’s disease, chronic renal failure, dehydration, and diabetic acidosis can cause high levels of magnesium. Alcoholism, hemodialysis, cirrhosis of the liver, pancreatitis, and too much insulin can cause low levels of magnesium. 6. What are the tests or procedures to assess the nutrient level in the body? Blood tests are usually taken to assess the levels of magnesium in the body (serum magnesium test). Levels tend to be checked when other levels are being checked for certain diseases like diabetes or kidney problems. 7. What is the drug –nutrient interactions? Diuretics can increase the loss of magnesium in the urine. Some laxatives and antacids contain magnesium, when taken in large doses this can lead to excessive consumption. 8. How is the nutrient measured? When levels are taken with a blood test magnesium is measured in mg/dL. 9. What is the Upper Tolerable Limits? 10.What are the physical signs of deficiency? Loss of appetite, nausea, vomiting, fatigue, and weakness. As it worsens, numbness, tingling, muscle contractions and cramps, seizures, personality changes, abnormal heart rhythms, and coronary spasms. Severe deficiency can result in low levels of calcium and potassium in the blood. 11.What are physical signs of toxicity? Dietary intake doesn’t result in toxicity, but pharmacological doses of magnesium can result in diarrhea and abdominal cramping. Risk for toxicity increases with kidney failure. Signs include changes in mental status, nausea, diarrhea, appetite loss, muscle weakness, difficulty breathing, extremely low blood pressure, and irregular heartbeats.