Curriculum Vitae
Shigeru Okada
Department of Pediatrics
The Heritage College of Osteopathic Medicine
And
Edison Biotechnology Institute
206C Konneker Research Laboratories
Ohio University
Athens, OH 45701
Telephone: (740) 593-9656
Fax: (740) 593-4795
Email: okada@ohio.edu
Academic Preparation
1983, Bachelor of Science in Biology, Chiba University, Chiba, Japan
1985, Masters of Science in Biology, Niigata University, Niigata, Japan
1993, Doctor of Philosophy in Molecular and Cellular biology, Ohio University,
Athens, OH
Professional Work Experience
1985-1993
Research Assistant, Molecular and Cellular Biology Department
Ohio University, Athens, OH.
1993-2002
Postdoctoral Fellow, Edison Biotechnology Institute, Ohio
University, Athens, OH.
1999-2006
Instructor, The Heritage College of Osteopathic Medicine, Ohio
University, Athens, OH.
2006-present Senior Scientist, Edison Biotechnology Institute, Ohio University,
Athens, OH.
2006-present Assistant Professor, Department of Pediatrics, The Heritage
College of Osteopathic Medicine, Athens, OH.
Awards
1998
2004
2006
NIH travel award
Gordon conference travel award
The third international congress of the GRS and the IGF society
travel award
US Patent Application
PCT/US2005/044182 (Shigeru Okada, Sudha Sankaran, John J. Kopchick)
“Diagnosis of hyperinsulinemia and type II diabetes and protection against same based on
proteins differentially expressed in serum” (June 15, 2006)
Society Membership
 The Endocrine Society
 Sigma Xi, The Scientific Research Society, Ohio University chapter
Book Chapters
Kopchick JJ, Okada S, Coschigano KT 2002 Lessons from growth hormone (GH)
antagonist and GH receptor 'knockout' mice. In: Bouillon R (ed) Targets for growth
hormone and IGF-1 action. BioScientifica Ltd., Bristol
Okada S. and Wright-Piekarski J. (2011) Bone. In Laron Syndrome: from man to
mouse. Eds. Laron Z and Kopchick JJ Springer-Verlag GmbH Berlin, Heidelberg.
Peer Reviewed Publications
1. Novel serum protein biomarkers indicative of growth hormone doping in healthy
human subjects. Ding J, Okada S, Jørgensen JO, Kopchick JJ. Proteomics. 2011
Sep;11(17):3565-71. Epub 2011 Jul 27.
2. Identification of new biomarkers of low-dose GH replacement therapy in GHdeficient patients. Cruz-Topete D, Jorgensen JO, Christensen B, Sackmann-Sala
L, Krusenstjerna-Hafstrøm T, Jara A, Okada S, Kopchick JJ. J Clin Endocrinol
Metab. 2011 Jul;96(7):2089-97. Epub 2011 May 4.
3. Proteomic changes in the heart of diet-induced pre-diabetic mice. Cruz-Topete D,
List EO, Okada S, Kelder B, Kopchick JJ. J Proteomics. 2011 May 1;74(5):71627. Epub 2011 Feb 24.
4. Insulin receptor substrates form high-molecular-mass complexes that modulate
their availability to insulin/insulin-like growth factor-I receptor tyrosine kinases.
Fukushima T, Arai T, Ariga-Nedachi M, Okajima H, Ooi Y, Iijima Y, Sone M,
Cho Y, Ando Y, Kasahara K, Ozoe A, Yoshihara H, Chida K, Okada S, Kopchick
JJ, Asano T, Hakuno F, Takahashi S.Biochem Biophys Res Commun. 2011 Jan
21;404(3):767-73. Epub 2010 Dec 17.
5. Endocrine parameters and phenotypes of the growth hormone receptor gene
disrupted (GHR-/-) mouse. List EO, Sackmann-Sala L, Berryman DE, Funk K,
Kelder B, Gosney ES, Okada S, Ding J, Cruz-Topete D, Kopchick JJ. Endocr
Rev. 2011 Jun;32(3):356-86. Epub 2010 Dec 1.
6. Serum proteome changes in acromegalic patients following transsphenoidal
surgery: novel biomarkers of disease activity. Cruz-Topete D, Christensen B,
Sackmann-Sala L, Okada S, Jorgensen JO, Kopchick JJ. Eur J Endocrinol. 2011
Feb;164(2):157-67. Epub 2010 Nov 8.
7. Plasma Protein Biomarkers Correlated with the Development of Diet-Induced
Type 2 Diabetes in Mice. Okada S, List EO, Sankaran S, Kopchick JJ. Clin
Proteomics. 2010 Jun 1;6(1-2):6-17.
8. Human growth hormone expressed in tobacco cells as an arabinogalactan-protein
fusion glycoprotein has a prolonged serum life. Xu J, Okada S, Tan L, Goodrum
KJ, Kopchick JJ, Kieliszewski MJ. Transgenic Res. 2010 Oct;19(5):849-67. Epub
2010 Jan 30.
9. Two-year body composition analyses of long-lived GHR null mice. Berryman
DE, List EO, Palmer AJ, Chung MY, Wright-Piekarski J, Lubbers E, O'Connor P,
Okada S, Kopchick JJ. J Gerontol A Biol Sci Med Sci. 2010 Jan;65(1):31-40.
Epub 2009 Nov 9.
10. Perspective: proteomic approach to detect biomarkers of human growth hormone.
Ding J, List EO, Okada S, Kopchick JJ. Growth Horm IGF Res. 2009
Aug;19(4):399-407. Epub 2009 Jun 4. Review.
11. Age-related changes in body composition of bovine growth hormone transgenic
mice. Palmer AJ, Chung MY, List EO, Walker J, Okada S, Kopchick JJ,
Berryman DE. Endocrinology. 2009 Mar;150(3):1353-60. Epub 2008 Oct 23.
12. The use of proteomics to study infectious diseases. List EO, Berryman DE, Bower
B, Sackmann-Sala L, Gosney E, Ding J, Okada S, Kopchick JJ. Infect Disord
Drug Targets. 2008 Mar;8(1):31-45.
13. Analysis of mouse skin reveals proteins that are altered in a diet-induced diabetic
state: a new method for detection of type 2 diabetes. List EO, Berryman DE,
Palmer AJ, Qiu L, Sankaran S, Kohn DT, Kelder B, Okada S, Kopchick JJ.
Proteomics. 2007 Apr;7(7):1140-9.
14. Application of Bioinformatics and Scalable Computing to Perform Proteomic
Analysis of Stomach tissue from Diabetic Mice. List EO, BerrymanDE, Palmar
AJ, Gosney E, Okada S,Kelder B, Lichtenberg J, Welch LR, Kopchick JJ.
Scalable Computing 2007 8:173-183
15. Perspective: proteomics--see "spots" run. Kopchick JJ, List EO, Kohn DT, Keidan
GM, Qiu L, Okada S. Endocrinology. 2002 Jun;143(6):1990-4.
16. Growth hormone receptor antagonists: discovery and potential uses. Kopchick JJ,
Okada S. Growth Horm IGF Res. 2001 Jun;11 Suppl A:S103-9.
17. Biological effects of growth hormone and its antagonist. Okada S, Kopchick JJ.
Trends Mol Med. 2001 Mar;7(3):126-32.
18. A mammalian model for Laron syndrome produced by targeted disruption of the
mouse growth hormone receptor/binding protein gene (the Laron mouse). Zhou
Y, Xu BC, Maheshwari HG, He L, Reed M, Lozykowski M, Okada S, Cataldo L,
Coschigamo K, Wagner TE, Baumann G, Kopchick JJ. Proc Natl Acad Sci U S
A. 1997 Nov 25;94(24):13215-20.
19. Growth hormone (GH) and a GH antagonist promote GH receptor dimerization
and internalization. Harding PA, Wang X, Okada S, Chen WY, Wan W,
Kopchick JJ. J Biol Chem. 1996 Mar 22;271(12):6708-12.
20. Effects of growth hormone antagonists on 3T3-F442A preadipocyte
differentiation. Xu BC, Chen WY, Gu T, Ridgway D, Wiehl P, Okada S,
Kopchick JJ. J Endocrinol. 1995 Jul;146(1):131-9.
21. In vitro mutagenesis of growth hormone receptor Asn-linked glycosylation sites.
Harding PA, Wang XZ, Kelder B, Souza S, Okada S, Kopchick JJ. Mol Cell
Endocrinol. 1994 Dec;106(1-2):171-80.
22. A growth hormone (GH) analog can antagonize the ability of native GH to
promote differentiation of 3T3-F442A preadipocytes and stimulate insulin-like
and lipolytic activities in primary rat adipocytes. Okada S, Chen WY, Wiehl P,
Kelder B, Goodman HM, Guller S, Sonenberg M, Kopchick JJ. Endocrinology.
1992 Apr;130(4):2284-90.
23. Expression of truncated forms of the bovine growth hormone gene in cultured
mouse cells. McAndrew SJ, Chen NY, Wiehl P, DiCaprio L, Yun J, Wagner TE,
Okada S, Kopchick JJ. J Biol Chem. 1991 Nov 5;266(31):20965-9.
24. Calmodulin activates adenylate cyclase from rat anterior pituitary. Greenlee DV
and Okada S. Mol Pharmacol. 1987 Dec;32(6):743-8.
25. Cathepsin D-like acid protease in the mantle of the marine mussel, Mytilus Edulis.
Okada S and Aikawa T. Comp Biochem Physiol. 1986 Mar 84B(3): 333-341.
Conference Poster Presentations/Published Abstracts
1.
2.
Okada, S., Chen, W.Y., Kelder, B., Wiehl, P. and Kopchick, J.J. A mutation in
bovine growth hormone alters its ability to induce adipocyte differentiation. J.
Cell. Biochem. (Abstract, Keystone Symposium on Molecular and Cellular
Biology), Supp. 15B, p. 21, 1991.
Xu, B., Okada, S., Wang, X. and Kopchick, J.J. Induction fo c-fos and aP2 RNA
by bGH and a bGH analogue. FASEB J., Vol. 6, No. 5, Pg. A1637 (#4059),
February 28, 1992.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
Okada, S., Wiehl, P. and Kopchick, J.J. Antagonism of bovine growth hormone
(bGH) stimulated glucose transport by a bGH analog in 3T3-F442A adipose cells.
FASEB J., Vol. 6, No. 4, Pg. A1272 (#1943), February 26, 1992.
Woodley, F.W., Kelder, B., Okada, S., Harding, P. and Kopchick, J.J. Effects of
introns on bGH gene expression in cultured cells. FASEB J., Vol. 6, No. 5, Pg.
A1643 (#4095), February 28, 1992.
Okada, S., Wiehl, P., Chen, W.Y., and Kopchick, J.J. A single amino acid
substitution of bovine growth hormone (GLY-119 to ARG) is sufficient for
generation of a functional GH antagonist. FASEB J., Vol. 7, No. 3, Pg. A374
(#2164), February 19, 1993.
Xu, B.X., Chen, W.Y., Wiehl, P., Okada, S. and Kopchick, J.J. Studies on growth
hormone (GH) inducible events during 3T3-F442A preadipocyte differentiation
using GH antagonists, bGH-G119R and hGH-G120R. FASEB J., Vol 8, No. 4,
Pg. A638 (#3699), March 15, 1994.
Okada, S. and Kopchick, J.J. Anti-diabetogenic effect of growth hormone
antagonists. Keystone Symposia, Supp. 18A, #CZ218, January 4-23, 1995.
Okada, S. and Kopchick, J.J. Growth hormone stimulates phosphatidylcholine
breakdown and activation of protein kinase C-F442A cells. Endocrine
Society, 77th Annual Meeting, June 14-17, 1995.
Okada, S. and Kopchick, J.J. Effects of Growth Hormone Antagonist (hGHG120R) on 3T3-F442A Adipocytes. Diabetes, 55th Annual Meeting, June 10-13,
1995.
Okada, S. and Kopchick, J.J. Growth Hormone Inhibits Translocation of Protein
Kianse C- and - Stimulated by Insulin in 3T3-F422A Cells. Endocrine Society,
78th Annual Meeting, Vol. 1, Pg. 275 (#P1-561), June 12-15, 1996.
List, E., Okada, S., Kelder, B. and Kopchick J.J. Characterization of an AntiMouse Growth Hormone Receptor Ribozyme. Endocrine Society, 79th Annual
Meeting, June 11-14, 1997.
Arman, A., Kelder, B., Okada, S. and Kopchick, J.J. The Effect of Deletion and
repositioning of Intracellular Regions of the GHR on GH Mediated Signal
Transduction. Endocrine Society, 79th Annual Meeting, June 11-14, 1997.
Okada, S. and Kopchick J.J. Growth Hormone and Insulin Stimulate Different
Subsets of Protein Kianse C Isotypes Through Different Mechanisms. Endocrine
Society, 79th Annual Meeting, June 11-14, 1997.
List, E.O., Okada, S., Kelder, B. and Kopchick, J.J. Decreased Biological Function
of Mouse Growth Hormone Receptor (GHR) Mediated by a GHR Ribozyme.
Endocrine Society, 80th Annual Meeting, June 24-27, 1998.
Okada, S., Bartke, A. and Kopchick, J.J. Expression of Mouse Prolactin cDNA in
Transgenic Mice. Endocrine Society, 80th Annual Meeting, June 24-27, 1998.
Okada, S., Bellush, L.L., Holland,A.N., Kopchick, J.J. Altered Protein Kinase C-
Activation and Glucose Tolerance in Transgenic Mice Expressing a Bovine Growth
Hormone Antagonist on High-Fat Diet. Endocrine Society, 81st Annual Meeting,
June 12-15, 1999.
List, E.O., Okada, S., Kelder, B., Kopchick, J.J. Decreased Weight in Mice
Containing a Growth Hormone Receptor (GHR) Ribozyme (RZ) Gene. Endocrine
Society, 81st Annual Meeting, June 12-15, 1999.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
Okada, S. and Kopchick, J.J. Binding Studies of Pegvisomant (Somavert) to
Hepatic Growth Hormone Receptors. Endocrine Society, 85th Annual Meeting,
June 19-22, 2003.
Okada, S., Sankaran, S., List, E.O. and Kopchick, J.J. Evaluation of High-Fat Fed
Mice as a Model of Obesity and Type II Diabetes. Endocrine Society, 86th Annual
Meeting, June 16-19, 2004.
Fukushima, T., Okajima, H., Ariga, M., Hakuno, F., Okada, S., Kopchick, J.J. and
Takahashi, S.I. A Novel Mechanism for cAMP-Dependent Amplification of IRS-2
Tyrosine Phosphorylation Induced by IGF-I. Endocrine Society, 86th Annual
Meeting, June 16-19, 2004.
Okada, S., Sankaran, S., Luring, C.B., Buchholtz, M., Keeton, S.M., Kopchick, J.J.
Proteomic Analysis of Type 2 Diabetic Mice Fed a High-Fat Diet. Endocrine
Society, 87th Annual Meeting, June 4-7, 2005.
Agote-Robertson, M., List, E.O., Sankaran, S., Luring, C.B., Kohn, D.T., Okada,
S., Palmer, A.J., Kopchick, J.J. Proteomic Analysis of Hearts and Kidneys of GH
Transgenic Mice with Reduced Life Span. Endocrine Society, 87th Annual
Meeting, June 4-7, 2005.
Okada, S., Sankaran, S., Kopchick, J.J. Analysis of the Serum Proteome of Diet
Induced Type 2 Diabetic Mice. Endocrine Society, 88th Annual Meeting, June 2328, 2006.
Ding, J., Sankaran, S., Okada, S., Kopchick, J.J. Small Molecular Weight Serum
Protein Profiles of Growth Hormone (GH) Transgenic and GH Receptor/Binding
Protein Gene Disrupted Mice. Endocrine Society, 88th Annual Meeting, June 2328, 2006.
Okada, S., Sankaran, S., Keeton, S.M., Freda, P.U., Jorgensen, J.O., Trainer, P.J.,
Kopchick, J.J. Proteomic Analysis of serum from Patients with Acromegaly.
Endocrine Society, 88th Annual Meeting, June 23-28, 2006.
Xu, J.F., Okada, S., Goodrum, K.J., Kopchick, J.J. and Kieliszewski, M.J. Highyields and extended serum half-life of therapeutic proteins expressed as fusion
glycoproteins in tobacco cells. In Vitro Cellular & Developmental BiologyAnimal, 42:22A-22A, Suppl. S, SPR, 2006.
Okada, S., Sankaran, S., Hartge, F., Kopchick, J.J. Isoforms of Plasma Retinol
Binding Protein, Transthyretin and Contrapsin Differ in Mice as They Develop
Diet Induced Diabetes: A Proteomic Study. Endocrine Society, 89th Annual
Meeting, June 2-5, 2007.
Okada, S., Sankaran, S., Hartge, F., Freda, P.U., Jorgensen, J.O.L., Kopchick, J.J.
Changes in Selected Isoforms of Retinol Binding Protein 4, Apolipoprotein A-1,
Haptoglobin, and Contrapsin as Novel Markers for Disease Control during
Pegvisomant Treatment of Acromegaly. Endocrine Society, 89th Annual Meeting,
June 2-5, 2007.
Ding, J., Sankaran, S., Hartge, F., Okada, S., Kopchick, J.J. Plasma Protein
Profiles of Growth Hormone (GH) Transgenic and Normal Mice at Different Ages.
Endocrine Society, 89th Annual Meeting, June 2-5, 2007.
Okada, S., Sankaran, S., Kopchick, J.J. Post-Translational Modification of Plasma
Retinol Binding Protein during the Development of Diet Induced Diabetes Involves
Phosphorylation and Proteolytic Cleavage. Endocrine Society, 90th Annual
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
Meeting, June 15-18, 2008.
Magon, V., Palmer, A.J., List, E.O., Okada, S., Kopchick, J.J., Berry man, D.E.
Body composition and adipokine levels in growth hormone antagonist mice.
Endocrine Society, 91st Annual Meeting, June 10-13, 2009.
Okada, S., Webb, C., Niemiec, N., Jorgensen, J.O.L., Kopchick, J.J. Serum
biomarkers of growth hormone action. Endocrine Society, 91st Annual Meeting,
June 10-13, 2009.
Kelder, B., Berryman, D.E., Okada, S., List, E.O., Tarnowski, M., Kopchick, J.J.
Generation and characterization of transgenic mice expressing the human CIDE-A
cDNA. Endocrine Society, 91st Annual Meeting, June 10-13, 2009.
Miles, D.B., List, E.O., Okada, S., Kopchick, J.J, Berryman, D.E. Depot-related
differences in receptors in C57BL/6J mice. Endocrine Society, 91st Annual
Meeting, June 10-13, 2009.
Cruz-Topete, D., Okada, S., List, E.O., Kopchick, J.J. Proteomic analysis of
insulin sensitive-tissues of type 2 diabetic mice fed a high fat diet. Endocrine
Society, 91st Annual Meeting, June 10-13, 2009.
Okada, S., Xu, J., Sankaran, S., Kieliszewski, M.J., Kopchick, J.J. O-Linked
glycosylation of growth hormone enhances its plasma half-life and in vivo activity.
Endocrine Society, 92nd Meeting and Expo of the Endocrine Society, San Diego,
CA. Endocrine Reviews: Volume 31, Issue 3, Supplement 1. June, 2010.
Tanda, H., Kelder, B., Berryman, D.E., Okada, S., Tarnowski, M., List, E.O.,
Kopchick, J.J. Effects of transgenic human CIDE-A expression on body
composition and lipid accumulation in mice. Endocrine Society, 92nd Meeting and
Expo of the Endocrine Society, San Diego, CA. Endocrine Reviews: Volume 31,
Issue 3, Supplement 1. June 2010.
Cruz-Topete, D., List, E.O., Okada, S., Kelder, B., Kopchick, J.J. Identification of
cardiac biomarkers ina mosue model of obesity induced type 2 diabetes. Endocrine
Society, 92nd Meeting and Expo of the Endocrine Society, San Diego, CA.
Endocrine Reviews: Volume 31, Issue 3, Supplement 1. June 2010.
Cruz-Topete, D., List, E.O., Okada, S., et.al. Identification of cardiac biomarkers
in a mouse model of obesity induced type 2 diabetes. 92nd Meeting and Expo of the
Endocrine Society, San Diego, CA. Endocrine Reviews: Volume 31, Issue 3,
Supplement 1. June 2010.
Okada, S., Xu, J., Sankaran, S., Kieliszewski, M.J., Kopchick, J.J. O-Linked
glycosylation of growth hormone enhance its plasma half-life and full retention of
bioactivity. 93rd Annual Endocrine Society Meeting, Boston, MA, June 4-7, 2011.
Oral Presentations
Okada. S. (May 18, 2009) “Early Diagnosis of Type 2 Diabetes Using Serum Retinol
Binding Protein 4 as a Biomarker”. Joint Meeting on Obesity Research Madrid, SPAIN.
Okada. S. (May 15, 2009) “Early Diagnosis of Type 2 Diabetes Using Serum Retinol
Binding Protein 4 as a Biomarker”. Endocrine Retreat, Rotterdam, NETHERLANDS.
Okada. S. (Oct 25, 2008) “Post-Translational Modification of Plasma Retinol Binding
Protein During the Development of Diet Induced Diabetes Involves Phosphorylation and
Proteolytic Cleavage”. NIH Sponsored Endocrine Retreat, Port Isobel, VA.
Okada. S. (July 18, 2008) “Post-Translational Modification of Plasma Retinol Binding
Protein During the Development of Diet Induced Diabetes Involves Phosphorylation and
Proteolytic Cleavage”. Appalachian Rural Health Institute/Diabetes Research Initiative
Retreat, Athens, OH
Okada. S. (February 8, 2008) “Proteomic Analysis of Serum from patients with
Acromegaly”. Prolactin Growth Hormone Gordon Conference. Ventura, CA
Okada. S. (September 20, 2007) “Change in Isoforms of Plasma Proteins in mice as they
develop diet induced diabetes”. Salt Fork, OH
Okada. S. (Oct 24, 2007) “Proteomic Analysis of Serum from patients with
Acromegaly”. Endocrine Retreat, Bushkill, PA.
Okada. S. (November 15, 2006) “Proteomics Analysis of Serum from Patients with
Acromegaly” The Third International Congress of the GRS and the IGF society), Kobe,
Japan.
Okada. S. (June 29, 2006) “Analysis of Serum Proteome of Diet Induced Type 2
Diabetic Mice” Ohio Collaborative Conference on Bioinformatics (OCCBIO), Athens,
OH.
Okada. S. (April 24, 2006) “Proteomic Analysis of Serum from humans with Different
GH Physiology”. Endocrinology Retreat, Edison Biotechnology Institute Athens, OH.
Okada. S. (August 9, 2005) “Proteomic Analysis of Type 2 Diabetic Mice Fed a HighFat Diet”. Appalachian Rural Health Institute/Diabetes Research Initiative Seminar
Series, Ohio University, Athens, OH.
Okada. S. (February 25, 2005) “Diabetes and Growth Hormone”. Edison
Biotechnology Retreat, Ohio University.
Okada. S. (August 30, 2004) “Evaluation of High-Fat Fed Mice as a Model of Obesity
and Type II Diabetes.” Endocrinology Retreat, Paris, FRANCE.
Okada. S. (June 2, 2000) “Altered Protein Kinase C- Activation and Glucose Tolerance
in Transgenic Mice Expressing a Bovine Growth Hormone Antagonist on High-Fat
Diet.” Growth Hormone and Prolactin NIH Sponsored Endocrine Retreat, Port Isobel,
VA.
Conference Session Organizer
Okada. S. (June 2, 2008) “Proteomics and Protein Analysis”. Ohio Collaborative
Conference on Bioinformatics (OCCBIO), Toledo, OH.
Internal Funding
Okada S, Berryman DE, Kopchick JJ, Harrington P, Welch L
Role: PI
Title: The effect of obesity and diabetes on protein expression
Agency: Appalachian Rural Health Institute Diabetes Research Initiative, Ohio University
2007
Value: $ 8,000.00
Okada S, Berryman DE, Kopchick JJ,
Role: PI
Title: Characterization of Retinol Binding Protein 4 as Early Diabetes Marker
Agency: Appalachian Rural Health Institute Diabetes Research Initiative, Ohio University
2009
Value: $ 8,000.00
External Funding
Okada S, Kopchick JJ.
Role: PI
Title: Measurement of GH Activities Using Adipose Cell Line
Agency: Pfizer Sponsored Research Agreement
01/01/07-12/31/07
Value: $55,473.00
Okada S, Kopchick JJ.
Role: PI
Title: Analysis of Glycated GH Antagonist
Agency: Phyton Sponsored Research Agreement
Value: $71,662.00
11/01/07-02/28/08
Kopchick (PI)
07/01/01-06/30/06
Role: Co-Investigator
Title: Proprietary & Confidential, but the general strategy is to identify genes and proteins
using micro arrays and proteomics that are involved in diabetes.
Aagency: DiAthegen, LLC
Value: $450,000/year
University Service
Graduate Student Committee Member (Graduation Year)
Yufeng Zhai (2009) “A ketogenic diet in mice for induction of weight loss: health
ramifications”
Zealand Muccio (2010) “Isotope ratio mass spectrometry – A rapidly developing tool for
forensic samples”
Tianxu Yang (2010) “Diet-induced obesity in growth hormone receptor antagonist mice”
Xiabo Sun (2012) “Forensic Applications of Gas Chromatography/Mass Spectrometry,
High Performance Liquid Chromatography--Mass Spectrometry and Desorption
Electrospray Ionization Mass Spectrometry with Chemometric Analysis”
Yan An (2013) “The potential of bulk and amino-acid specific isotope ratio mass
spectrometry of human hair in forensic and clinical applications”
Adam Jara (current) “”
All Undergraduate Students Mentored in the Laboratory
Allen Gattis (1997-1998)
Takuya Aoki (2001-2003)
Hiroshi Sugita (2002-2003)
Megan Buchholz (2004-2005)
Stephanie Keeton (2004-2005)
Christopher Luring (2005)
Christopher Varacallo (2006)
Maria R. Beigel (2007)
Maegan E. Dodson (2007-2009)
Christopher Webb (2008)
Adam Jara (2009)
Nicholas K. Niemiec (2009)
Andrew Rotowski (2009-2011)
Spencer L. Hirt (2010)
Clare Vesel (2012)
Angela Zakonova (2012)
Miscellaneous/Service
 Ohio University Radiation Safety Committee Core Voting Member (1993-present)Served
on the Diabetes Institute at Ohio University committee to hire a grant writer
 Sigma Xi, The Scientific Research Society, Ohio University chapter, Treasurer and
Secretary (2007-2012)