Anatomy and Physiology Exam Review INTRODUCTION Introduction to the Human Body Anatomy and physiology definitions Levels of structural organization Characteristics of Life Know each and purpose Relationship between body temperature Define homeostasis Body Systems Basic functions of each Anatomical Position Know the anatomical position Common directional terms o Superior, inferior, posterior, medial, lateral, proximal, distal, superficial, deep Body planes o Know all (including alternative names in parentheses) Body Cavities Axial vs. appendicular Ventral body cavity o Thoracic and abdominopelvic/diaphragm CHEMISTRY Basis of Life Define matter Three states of matter Physical vs. chemical change Composition of Matter Most abundant elements in the body Three major subatomic particles Isotopes o Medical uses Reactions Ionic bonds Covalent bonds o Nonpolar o Polar Hydrogen bonds Anabolism vs. catabolism vs. exchange Biochemistry Organic vs. inorganic compounds Why an acid is an acid and a base is a base o pH scale Carbohydrates o Purpose they serve in the body o Mono- vs. di- vs. polysaccharide Examples of each ATP o Role o Structure o Location of energy in the molecule Lipids o Functions Proteins o Functions CELLS Anatomy of a Cell Basic cell functions Organelle structure/function o Nucleus, nucleoli, ribosomes, ER, golgi apparatus, lysosomes, mitochondria o Route of protein export Membrane Transport Selective permeability of a cell membrane Diffusion/passive transport vs. active transport (energy requirements) o Up vs. down a concentration gradient Hypo-/hypertonic o Which way a fluid go in a particular set of circumstances Cell Division Mitosis o Stages and basic events of each o Number of chromosomes at start/finish Mitosis vs. meiosis (purpose of each) o Haploid vs. diploid Body Tissues Four principal tissue types o Epithelial Two types Types of epithelium Shapes/arrangements o Examples/functions Role of keratin o Connective Classification Loose, dense, cartilage, bone, blood, embryonic Function examples Characteristics Cells (living) vs. matrix (nonliving) “Blast” vs. “cyte” cell types Role of “phage” cells Adipose functions Tendon connective tissue type Muscle Function Type names Nervous Function Type names INTEGUMENTARY Introduction Functions of the skin Skin layer locations (dermis vs. epidermis) Functions of the following: o Keratinocytes, melanocytes, Langerhans cells, Merkel cells, melanin Skin disorders o Albinism, vitiligo, cyanosis, jaundice, erythema Epidermal Derivatives Hair anatomy o Layers of the hair shaft o Role of arrector pili muscles Three gland types o Function, what they create/do for the skin/body Nails o Three main parts (location/what it is) o Lunula, eponychium, hyponychium (location/what it is) Wounds o Deep wound healing phases (names) o Burn degree categories (basics) SKELETAL Introduction/Histology Axial vs. appendicular skeleton Skeletal system functions Structure of bone (structure/function of each) o Diaphysis, epiphysis, metaphysis, articular cartilage, periosteum, medullary canal, endosteum, epiphyseal line/plate Histology o Osteoprogenitor vs. osteoblast vs. osteocyte vs. osteoclast Microscopic anatomy o Volkmann’s vs. Haversian canals o Haversian systems as a bone unit (osteon) Bone Ossification Intramembranous o Define o Examples/which bones are formed this way Endochondral o Define o Examples/which bones are formed this way Growth of cartilage model o Grow in length/thickness (appositional) Development of primary ossification center o Cells/structures involved Bones of the Skull Define sutures and fontanels Know the six bones of the neurocranium o Be able to label as you have in class Know the eight bones of the viscerocranium (facial bones) o Know basic characteristics Bone markings Why they’re present Know basics of the following: o Meatus, foramen, groove, notch, head, crest Articulations Structural classifications – fibrous, cartilaginous, synovial Vertebral Column and Thoracic Cage Normal curves o Characteristics, locations, names Abnormal spine curvatures o Scoliosis, lordosis, kyphosis Divisions of the vertebral column o Know all five and number of vertebrae in each o Know how the size/shape of each type is different Characteristics of atlas/axis Know three processes o Spinous, transverse, articular Function of intervertebral disks Thoracic cage o Structures included o Functions Ribs o True vs. false vs. floating Sternum o Three parts/locations Appendicular skeleton Bones of pectoral girdle o Purpose of clavicle Know the locations of the bones of the upper and lower extremities (ex. Humerus, radius, fibula, femur, etc.) Three bones of the pelvic girdle o Ilium, ishium, pubis o Purpose of pubic symphysis MUSCULAR The Muscular System/Muscular Tissue Three major types (skeletal, smooth, cardiac) o Basic anatomical differences o Locations of each in the body Individual muscle fiber o Sarcolemma vs. sarcoplasm vs. sarcoplasmic reticulum o Myofilaments containing actin and myosin Know which are light/dark and thick/thin Lead to striations Physiology What is happening at this level when a muscle contracts Muscle activity o Know four characteristics of muscle tissue and define Neuromuscular Junction Motor unit Fine vs. course muscle control Role of acetylcholine, synaptic cleft, interstitial fluid Depolarization vs. repolarization Role of calcium during muscle contraction Role of acetylcholinesterase Energy sources for muscle contraction o Role of creatine phosphate o Purpose of glycolysis o Aerobic system Fate of pyruvic acid Production of ATP o Reasons for muscle fatigue Muscle Responsiveness Nature of all-or-none response Isotonic vs. isometric contractions Endurance vs. weight resistance exercise o Basics Naming Skeletal Muscles Names associated with size Names associated with shape 11 muscle actions (flexor, extensor, etc.) Names associated with direction of muscle fibers NERVOUS Nervous System/Introduction Three major roles of the nervous system Anatomical organization o CNS vs. PNS Functional organization o Sensory/integrative/motor Peripheral nervous system o Somatic Sensory vs. motor neurons o Autonomic Sensory vs. motor neurons Major divisions Sympathetic vs. parasympathetic Protection of the brain o CSF Role of CNF What makes CNF Hydrocephalus o Blood-brain barrier o Three layers of the meninges Roles and locations Regions of the brain o Cerebrum Location Grooves/gyri Function of this brain region Left vs. right hemisphere characteristics Why white matter is white Association fibers Importance of corpus callosum Functions of cerebral cortex o Diencephalon Thalmus Function Hypothalmus Function o Brain stem Three parts and location/function of each o Cerebellum Function Cranial and Spinal Nerves Names and basic function(s) of each Nervous Tissue Neuron vs. neuroglia Kinds of nerve fibers o Dendrites vs. axons (towards vs. away) o Myelin Importance, function, locations, appearance o Neuroglia Functions Functional classification of neurons o Afferent vs. efferent Pathways and Tracts Define pathway Ascending (sensory) vs. descending (motor) Reflex o Define o Two types o Reflex arc beginning and end SENSORY Hearing and Equilibrium Three major parts of the ear o External Function Three major structures o Middle Function Name three bones (maleus, incus, stapes) o Inner What it is Cochlea o Shape Organ of Corti o Significance Equilibrium o Static vs. dynamic Vision Visual pathway o Order and structures involved Photoreceptors o Rods. vs. cones Dim vs. light/which is important for color vision Emmetropic eye vs. ones with conditions o Myopia vs. hyperopia vs. astigmatism Causes Sense of smell (Olfactory) Three major cell types o Role of each Somatic and Special Senses Define senses Role of receptors Area of brain dedicated to sensory areas General senses o Somatic (list and define) o Visceral Special senses o Somatic (list and define) o Visceral (list and define) Skin receptors o Tactile sensations Four major touch receptors Name and what they sense Two vibration receptors o Pain sensations Nociceptors Referred pain Taste Three major epithelial cells Four taste sensations o Locations on tongue Anatomy of the Eyeball Location and function of the lens, cornea, pupil, cilliary body, retina, choroid, sclerea Cranial nerves associated with vision