Name: ____________________________________________ Period: ____ Date: ______________ Chp 9: NERVOUS TISSUE After identifying the organization of the nervous system into its subdivisions of the CENTRAL NERVOUS SYSTEM (CNS) and PERIPHERAL NERVOUS SYSTEM (PNS), the histology of the functional neuron cells and supportive neuroglial is considered. Attention is given to the components of a neuron, and their structural and functional classification. The physiology of nervous tissue is then discussed. The topic areas considered are plasma membrane ion channels, membrane potentials, excitability, the All-or-None Principle, saltatory conduction and speed of nerve impulses. The physiology of impulse conduction synapses are then considered. Particular attention is given to excitatory and inhibitory transmission, synaptic integration and alternation of synaptic conduction. Chp 11: THE AUTONOMIC NERVOUS SYSTEM Students are introduced to the general functions of the ANS and its comparison to the SNS. The sympathetic and parasympathetic divisions of the autonomic nervous system are introduced. Attention is then focused on the structure of the ANS, detailing the components of visceral efferent pathways. The components discussed are preganglionic neurons, autonomic ganglia, and postganglionic neurons. The functional aspects of the autonomic nervous system are then discussed by considering neurotransmitters and numerous ANS activities. Chp 12: SENSATIONS This chapter offers a general introduction to the location of sensory apparati and the way in which stimuli are detected. Somatic cutaneous sensations such as tactile and discriminative touch, pressure, pain, and temperature are considered. The special senses of smell, taste, vision, and hearing are then introduced with a discussion of the physiological features. OBJECTIVES Nervous Tissue 1. Describe the organization of the nervous system. 2. Compare the structure and functions of neuroglia and neurons. 3. Describe how a nerve impulse is generated and conducted. Autonomic Nervous System 1. Outline the main structural and functional differences between the somatic and autonomic nervous systems. 2. Identify the structural features of the autonomic nervous system. 3. Discuss the functions of the sympathetic and parasympathetic divisions of the autonomic nervous system. Sensations 1. Define a sensation and describe the conditions necessary for a sensation to occur. 2. List and describe the somatic sensations. 3. Define proprioception and describe the structure of proprioceptive receptors. 4. Describe the receptors for olfaction and the olfactory pathway to the brain. 5. Describe the receptors for gustation and the gustatory pathway to the brain. 6. Describe the receptors for vision and the visual pathways to the brain. 7. Describe the mechanism involved in vision. 8. Describe the receptors for hearing and equilibrium, and their pathways to the brain. ASSIGNMENTS 1. Read Chapter 9; pages 229-245. 2. Read Chapter 11; pages 277-288. 3. Read Chapter 12; pages 289-319. 4. Complete this packet as you read and listen to classroom lectures or discussions; answer all Checkpoint Questions and Critical Thinking Applications when directed to do so. 2 Chapter 9: Nervous Tissue I. OVERVIEW OF THE NERVOUS SYSTEM OBJ: Describe the organization of the nervous system. Explain the three basic functions of the nervous system. A. Organization of the Nervous System 1. Two main subsystems of the nervous system: a. ___________________________________________: consists of the brain and spinal cord i. Brain contains ~ ______________________ neurons ii. Spinal cord contains ~ _______________________ neurons and is encircled by bones of vertebral column. iii. Function: ____________________________________________________________ ____________________________________________________________________ ____________________________________________________________________ b. ___________________________________________: includes all nervous tissue outside the CNS. i. Components of PNS: (1) ___________________; bundle of hundreds to thousands of axons plus associated connective tissue and blood vessels lying outside the brain and spinal cord. Cranial nerves I-XII emerge from base of the brain. Spinal nerves emerge from spinal cord. (2) ___________________; are small masses of nervous tissue, consisting mostly of neuron cell bodies and are located outside the brain and spinal cord; closely associated with ________________ and _____________ nerves. (3) Enteric plexuses: Found: _______________________________________________ Function: _____________________________________________ (4) Sensory receptors: Found: _______________________________________________ Function: _____________________________________________ Recall: CNS - brain and spinal cord; integrates and correlates many different kinds of incoming sensory information; source of thoughts, emotions, and memories. PNS – cranial nerves and their branches, spinal nerves and their branches, ganglia, and sensory receptors; functions divided into subdivisions…. SUBDIVISIONS OF PNS: 1. Somatic nervous system (SNS) a. ______________________________: convey information from somatic receptors in head, body wall, and limbs, and from receptors for special senses of vision, hearing, taste, and smell to CNS b. __________________________: conduct impulses from CNS to _____________muscles only; can be consciously controlled, voluntary actions 3 2. Autonomic nervous system (ANS) a. _____________________________: convey information from autonomic sensory receptors, located in visceral organs (stomach, lungs) to CNS b. __________________________: conduct nerve impulses from CNS to ____________, ________________ muscles and glands; cannot be consciously controlled, involuntary actions c. Two divisions of ANS are: ____________________ and __________________________; these divisions usually perform opposite functions i. “Fight-or-flight” responses ____________________________ ii. “Rest-and-digest” activities ____________________________ 3. Enteric nervous system (ENS) a. Known as ___________________________________; operation is involuntary b. Neurons found in and extend through ________________________________________ c. _____________________________: monitor chemical changes within the GI tract and the stretching of its walls d. _________________________: govern ___________________ of GI tract smooth muscle, _____________________ of GI tract organs, and activity of GI tract endocrine cells. Get a copy of checkpoint questions 1-3 and the applicable critical thinking application, complete them and hand them in… B. Functions of the Nervous System 1. Sensory functions a. ______________________________ detect stimuli inside and outside the body. b. Types of neurons that carry out sensory functions: i. __________________________________________________ Carry sensory information to brain and spinal cord. 2. Integrative functions a. Do what? ________________________________________________________________________ ________________________________________________________________________ b. Types of neurons that carry out integrative functions: ________________________________________________________________________ ________________________________________________________________________ 3. Motor functions a. Do what? ________________________________________________________________________ b. Types of neurons that carry out motor functions: ________________________________________________________________________ ________________________________________________________________________ II. HISTOLOGY OF NERVOUS TISSUE OBJ: Contrast the histological characteristics and the functions of neurons and neuroglia. Distinguish between gray matter and white matter. What two types of cells make up nervous tissue? _________________________________________ 4 Neurons provide for what: __________________________________________________________________________________ __________________________________________________________________________________ What do neuroglia do? __________________________________________________________________________________ A. Neurons Consists of three parts: (1) ____________________ Contains: ____________________________________________________________________ What is synthesized here? ______________________________________________________ Processes or extensions: (2) ____________________(“little trees”) How many? __________________________ Combined with cell body what is their function? ____________________________________ Shape: _____________________________________________________________________ (3) ____________________ Function: ___________________________________________________________________ ___________________________________________________________________ Shape: _____________________________________________________________________ What is an axon hillock? _______________________________________________________ What are axon collaterals? _____________________________________________________ What are axon terminals? ______________________________________________________ What is a synapse? __________________________________________________________________ What are synaptic end bulbs? _________________________________________________________ What are synaptic vesicles? ___________________________________________________________ What are neurotransmitters? _________________________________________________________ 1. Classification of Neurons STRUCTURAL CLASSIFICATION ______________________________: have several dendrites and one axon; most in brain and spinal cord ______________________________: have one main dendrite and one axon; retina of the eye, inner ear, olfactory area of brain ______________________________: dendrites and one axon fused together forming a continuous process that emerges from cell body; begin in embryo as bipolar neurons; most function as sensory receptors for touch, pressure, pain, or thermal stimuli. Cell bodies of most of this type located in ganglia of spinal and cranial nerves. FUNCTIONAL CLASSIFICATION ______________________________: once sensory receptor activated, these form an action potential in their axon that is conveyed into the CNS through spinal and cranial nerves contain sensory receptors at their distal ends or are located just after sensory receptors that are separate cells; most unipolar in structure 5 ______________________________: convey action potential away from CNS to effectors (muscles and glands) in PNS through cranial and spinal nerves Most are multipolar in structure ______________________________: integrate incoming sensory information from sensory neurons and then elicit a motor response by activating appropriate motor neurons Located within CNS between sensory and motor neurons; most multipolar in structure B. Neuroglia Describe neuroglia: ______________________________________________________________ ______________________________________________________________ Functions: _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ What are gliomas? _________________________________________________________________ C. Myelination A myelin sheath, many-layered covering composed of lipids and protein, surround the axons of most of our neurons. Two Functions: (1) ________________________________________________________ (2) ________________________________________________________ What name is given to the gaps in myelin sheath? ____________________________________ Define myelinated: _____________________________________________________________ Define unmyelinated: ___________________________________________________________ The amount of myelin increases from ___________________ to ____________________ Its presence increase what? ________________________________________________ What two diseases are known to destroy myelin sheaths? ______________________________ D. Collections of Nervous Tissue 1. Clusters of Neuronal Cell Bodies __________________________: cluster of neuronal cell bodies located in PNS __________________________: cluster of neuronal cell bodies in CNS 2. Bundles of Axons ____________________: bundle of axons located in PNS; cranial nerves connect brain to periphery and spinal nerves connect spinal cord to periphery ____________________: bundle of axons located in CNS; tracts interconnect neurons in spinal cord and brain 3. Gray and White Matter What is white matter? ____________________________________________________________________ ____________________________________________________________________ What is gray matter? ____________________________________________________________________ ____________________________________________________________________ ____________________________________________________________________ 6 obtain and complete the worksheet ‘the anatomy of the neuron’ Quiz on nervous system basics on: __________________________________ Know the components of the CNS and PNS Know what the ANS, ENS, and SNS controls (Figure 9.1, page 254 may help) Know the anatomy of a neuron III. ACTION POTENTIALS OBJ: Describe how a nerve impulse is generated and conducted. What is another name for action potentials? ___________________________ What two features of plasma membrane do action potentials in muscle fibers and in neurons depend on? (1) ___________________________________________________________ (2) ___________________________________________________________ _________________________________, difference in the amount of electrical charge inside and outside a plasma membrane. A membrane that has potential is said to be ____________________. When muscle fibers and neurons are ‘at rest’, the voltage across the plasma membrane is termed the __________________________________________. In living tissues, the flow of ions constitutes electrical currents. A. Ion Channels Let specific ions move from areas of high concentration to areas of low concentration, or from positively charged areas to negatively charged areas or visa versa to equalize differences in charges or concentration. 1. Two types of ion channels: Leakage channels___________________________________________________________________________ ___________________________________________________________________________ Gated channels: ___________________________________________________________________________ ___________________________________________________________________________ 2. What are voltage-gated channels used for? ___________________________________________________________________________ B. Resting Membrane Potential 1. What kind of charge does the resting neuron have on the outside surface of the plasma membrane? _____________________________ on the inside? _______________________ 2. Potential energy in cells is measured in ____________. 3. What is the resting membrane potential in neurons? _________mV 4. Why is it a negative value? _____________________________________________________ 5. Interstitial fluid is rich in __________ ions and _____________ ions. 6. Cytosol is rich in ____________ ions. 7. What offsets the small inward leak of Na+ and outward leak of K+? ____________________________________ 7 8. The diagram below will help you to understand how resting membrane potential arises from the unequal distributions of various ions in cytosol and interstitial fluid. You should read over this material carefully on page 260 of your textbook. C. Generation of Action Potentials what happens during an action potential (AP) or impulse? ______________________________________________________________________________ ______________________________________________________________________________ Ability of muscle fibers and neurons to convert stimuli into action potential is called _______________________________. What causes an action potential to arise? ______________________________________________________________________________ 1. Two main phases: Depolarizing phase___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ Repolarizing phase___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ 8 2. Explain the process of action potential from threshold state to depolarization to afterhyperpolarization phase. ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ 3. What is the all-or none principle? ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ 4. What type of stimuli elicit an action potential? _____________________________________ 5. What is a refractory period? ___________________________________________________________________________ 6. Label 1-7 on the diagram below: 2. 3. 4. 5. 7. 1. 6. D. Conduction of Nerve Impulses What is propagation or conduction? ______________________________________________________________________________ What is continuous conduction? What type of axons does it occur in? ______________________________________________________________________________ What is saltatory conduction? What type of axons does it occur in? ______________________________________________________________________________ What type of axons have the largest diameter? ________________________________ What type of axons have the smallest diameter? _______________________________ What type of factors influence the speed of nerve impulse conduction? ______________________________________________________________________________ 9 IV. SYNAPTIC TRANSMISSION OBJ: Explain the events of synaptic transmission and the type of neurotransmitters used. What is synaptic transmission? __________________________________________________________________________________ __________________________________________________________________________________ What is the neuron sending the signal called? _________________________________________ What is the neuron receiving the signal called? ________________________________________ A. Events at a Chemical Synapse What separates the presynaptic and postsynaptic neurons? ____________________________ B. Neurotransmitters Different neurotransmitters are found in synaptic vesicles. These different neurotransmitters have different effects. Obtain and complete the synaptic events worksheet… When done with this packet you will receive packet for chapters 11 & 12… 10