Grade 11 Test questions practice _ HL_MS_SV 1. 2. 3. 4. 5. 6. 7. B D D C D A A 8. Outline a technique for transferring genes between species (5) 9. Describe the roles of mRNA, tRNA and ribosomes in translation (6) 10. C 11. C 12. D 13. B 14. A 15. Outline the structure of DNA. (5) 16. Explain the process of transcription in eukaryotes (8) 17. a. Draw the structure of a generalized dipeptide (4) b. Explain the process of translation leading to peptide linkage formation (8) 18. A 19. a. Determine the strand of mRNA that is transcribed from the DNA strand below (1) A–T–C–C–A–G–G–T–C–A–A–G b. List three of the other molecules, apart from mRNA, required for transcription. (3) 20. The following diagram represents replication in DNA. a. State the name and describe the function for the enzymes labelled A and B on the diagram. (2) b. Identify the cellular location of DNA replication in eukaryotic cells (1) c. State at which period during the cell cycle DNA replication occurs (1) d. Explain the significance of complementary base pairing during DNA replication (2) 21. B 22. D 23. a. State two differences between the structure of DNA and RNA (2) The diagram below shows the structure of a ribosome during protein synthesis b. State the names of the structures labelled above (2) c. State the name of a structure shown on the diagram that has an anticodon. (1) d. Explain why the process used during protein synthesis in cells is called translation. (2) e. Explain briefly how termination of translation occurs (2) 24. a. Describe four levels of protein structure, including each levels significance. (8) 25. C 26. C 27. Draw and label a simple diagram showing how DNA nucleotides are linked together in a single strand. (4) 28. Outline the significance of complementary base-pairing in DNA (5) 29. Outline the procedure used by Hershey and Chase which provides evidence that DNA is the genetic material (4) Radioactive tagging was used in two stages. 1. 2. The phosphorous present inside a virus was tagged using a radioactive isotope. The virus was placed in solution with bacteria. The virus injected genetic material into the bacteria. The bacterium was tested for radioactive isotopes. Test was positive, the radioactive phosphorous had entered the bacterium. Phosphorous is an essential part of DNA. A sulphur present on the outside (protein coat) of a virus was tagged using a radioactive isotope. The virus was placed in solution with bacteria. The bacterium were then tested for the radioactive isotopes. The test was negative. The radioactive isotopes had remained in the supernatant fluid above the cells. Sulpher is an essential component of the protein coat surrounding the outside of the virus. Only the genetic material is injected into the cell. 30. Outline how the work of Meselson & Stahl lead to the theory of semi conservative replication (4) 31. Allows precise replication of a DNA strand. Bases bond specifically (AT, CG). Meselson & Stahl proved this process by radioactively tagging nucleotides before replication and observing where the tags were after one replication. They concluded 50% of the original strand was present in a new strand. This was the evidence for semi conservative replication.