Lean LaunchPad for Life Science/Healthcare January 2015 Syllabus Course Director: Steve Blank Teaching Team: Lead Instructors Nancy Kamei, Entrepreneur in Residence, UCSF School of Pharmacy Stephanie Marrus, Director, Entrepreneurship Center at UCSF and Lecturer, UCSF Todd Morrill, I-Corps National faculty, Bay Area Faculty Director Cohort Instructors Therapeutics: Karl Handelsman, Codon Capital Digital Health: Lynne Chou, Partner, Kleiner Perkins Malay Gandhi, Managing Director, Rock Health Chris DeNoia, Advisor, DoctorBase Teaching Assistants Therapeutics: Robin Mansukhani, CEO, Alzeca Biosciences Digital Health: Kyra Davis, Program Manager, Entrepreneurship Center at UCSF Location: Dates: Office Hours: Suggested Texts: UCSF Mission Bay, Genentech Hall Thursdays, January 8 – March 19 3:45-4:45 pm prior to Thursday class. See online signup sheet. Startup Owner’s Manual: Blank & Dorf Business Model Generation: Osterwalder, et al Talking to Humans: Constable & Rimalovski 1 Online Lectures: On Udacity: How to Build a Startup: The Lean LaunchPad https://www.udacity.com/course/ep245 Software: Launchpad Central: https://launchpadcentral.com. Students will be provided with an account. Credit: This is a non-credit course at UCSF. Credit granted to MTM students by Berkeley. Why Take This Class? Over 400 teams have been trained in the Lean LaunchPad approach on how to commercialize their research. The approach has been proven to help startups fail less, and increase their odds for commercial success. Success in translating science or medicine requires more than creating better science or technology. A parallel track to optimize other elements of a business is essential for turning an idea into a viable company. Lean LaunchPad provides real world, hands-on learning on how to reduce commercialization risk in early-stage ventures. Teams rapidly: • Define clinical utility before spending millions of dollars • Understand their core and secondary customers and purchase influences • Learn the process required for initial clinical sales and downstream commercialization • Assess intellectual property and regulatory risk before they design and build • Know the data will be required by future partnerships/collaboration/purchases before doing the science • Identify financing vehicles before they are needed Course Objective This is a practical class – essentially a lab, not a theory or “book” class. Our goal, within the constraints of a classroom and a limited amount of time, is to help you find a repeatable and scalable business model for your company. This will allow you to build a company with substantially less money and in a shorter amount of time than using traditional methods. The class uses the Lean Startup method. Rather than engaging in months of business planning, the method assumes that all you have is a series of untested hypotheses—guesses about clinical utility, who the customer is, payers, regulation, intellectual property, clinical trial requirements, user requirements, customer acquisition, conversion rates, stickiness, business models, value proposition, etc. Regardless of how elegant your plan, the reality is that most of it is wrong. You need to get out of your lab or clinic to search for the facts that validate or invalidate your hypotheses, and ultimate enable you to pursue strategies that will accelerate the launch 2 and development of your business. Our class formalizes this search for a business model. We do it with a process of hypothesis testing that is familiar to every scientist and clinician. In this class you will learn how to use a Business Model Canvas -- a diagram of how a company will create value for itself and its customers-- to frame your hypotheses. Second, you will “get out of the building” using an approach called Customer Development to test your hypotheses. You will run experiments with customers/partners and collect evidence about whether each of your business hypotheses is true or false. Every week you will talk to customers, partners, regulators, payers and competitors, testing your assumptions about clinical utility, partners, IP, regulatory issues, product features, pricing, distribution channels. You will complete at least 100 interviews during the 10 weeks of class. Finally, based on the customer and market feedback you gathered, you will use agile development to rapidly iterate your product or concept to build/design something customers would actually buy and use. This class requires you to be nimble and fast. You will iterate on hypotheses and rapidly assemble minimum viable products (MVPs) to immediately elicit customer feedback. Using the input to revise your assumptions and hypotheses, you will start the cycle again, testing redesigned offerings and making further small adjustments (iterations) or more substantive changes (pivots) to ideas that are not working. This process of making substantive changes to one or more business model hypotheses – called pivots – before you raise and spend millions of dollars, helps avoid huge future costs and potentially unforeseen dead-ends when far down the road of development. A pivot might mean changing your position in the value chain. For example, your company may become an OEM supplier to hospitals rather than selling directly to physicians. Other pivots may move your company from a platform technology to a product or from a B2B play to B2C. Some teams may make even more radical changes. For example when one team in a prior course discovered the “right” customer, they changed the core technology which was the basis of their original idea to serve those customers. 3 Teaching Method The class uses eight teaching methods: 1. Experiential learning, 2. Teambased activity, 3. “Flipped” classroom, 4. Domain specific lectures, 5. Weekly presentations, 6. Team Teaching, 7. Providing feedback to other teams and 8. LaunchPad Central. 1. Experiential Learning This class is not about the lectures. The learning occurs outside of the classroom through conversations with customers. Each week your team will conduct a minimum of 10 customer interviews focused on a specific part of the Business Model Canvas. This class is a simulation of the real world for startups and entrepreneurship: chaos, uncertainty, impossible deadlines with insufficient time, conflicting input, etc. 2. Team-based Class activities will be performed by your team of 3 to 5 people. You will be admitted as a team. The commitment of the entire team to the effort and necessary time expenditure is a key admission criterion. Teams will self‐organize and establish individual roles on their own. There are no formal CEO/VP’s, just the constant parsing and allocating of the tasks that need to be done. Every team member must participate in Customer Discovery activities -- out of the building hypotheses testing -- talking with customers and partners. You cannot delegate Customer Discovery. In addition to the instructors and TA, each team will be assigned a mentor to provide assistance and support. 3. The Flipped Classroom Unlike a traditional classroom where the instructor presents lecture material, you will watch core weekly lectures before coming to class. These lectures contain the information you will need to complete that week’s customer interviews. Class time will be allocated to weekly team progress updates rather than lectures. The Teaching Team and mentors provide personalized guidance to each team. The work you present weekly will be based on the online lecture you watched the prior week and the in-class cohort lecture. 4. Domain Specific Lectures Online lectures will be supplemented by in-class lectures and discussions tailored to your specific cohort: therapeutics or digital health. 4 5. Weekly Team Presentation of Progress Each week all teams will present a summary of what they learned when testing specific hypotheses. The Teaching Team will provide advice and guidance. 6. Team Teaching and the Inverted Lecture Hall Experienced instructors and mentors who have built and/or funded world class startups and have worked with countless entrepreneurial teams sit at the back of the classroom. They will comment on and critique each team’s progress. While the comments may be specific to each team, the insights are almost always applicable to all teams. 7. Actively Observing Other Teams and Providing Written Constructive Feedback and Grades The class is a learning cohort. It is your responsibility to help each other and learn from one another’s experiences. This form of collaborative learning will accelerate your team’s progress. Each week, when other teams are presenting, you will be logged into the class online management tool, LaunchPad Central, where you will provide feedback, ideas, helpful critiques and suggestions for each team as they present. You will also assign a grade solely on your individual assessment of their performance. This feedback is viewable by all members of the class, and may – at the discretion of the instructors – be shared for class discussion. 8. Keeping Track of Your Progress: LaunchPad Central (LPC) Each week as you get of the building and talk to customers you will summarize what you learned using an online tool, LaunchPad Central. The tool automatically collects and displays your current hypotheses and the hypotheses you have invalidated through interviews. This allows you to share your learnings with the Teaching Team and mentors. We monitor your progress through this tool. Class Culture Startups communicate much differently from the university or company culture you may be familiar with. At times the communication may feel relentlessly direct, but in reality it is focused and designed to create immediate action in time-, resource-, and cash-constrained environments. We have limited time and we push, challenge, and question you in the hope that you will learn quickly. The pace and uncertainty accelerate as the class proceeds. We will be direct, open, and tough – just like the real world. This approach may seem harsh or abrupt, but it is a direct reflection of our desire for you to learn to challenge yourselves quickly and objectively, and to appreciate that as entrepreneurs you need to learn and evolve faster than you ever imagined possible. This class pushes many people past their comfort zone. If you believe that the role of your instructors is to praise in public and criticize 5 in private, do not take this class. You will be critiqued in front of your peers. Time Commitment Teams that have completed this course report spending 15- 20 hours each week on course activities. Most of the effort is getting out of the classroom and interviewing. Teams are expected to complete at least 10 in-person or Skype video interviews each week focused on the Business Model Canvas area of emphasis for that week. Over the 10-week course you will have completed 100 or more interviews. If you are too busy to meet this commitment, do not take this class. Every team member must complete customer interviews; you cannot delegate. Homework You are expected to complete 10-15 interviews per week and prepare a presentation summarizing what you have learned, in addition to watching online videos and reading. You will not be invited to present in class if your interviews are incomplete. Telephone interviews, which are never as good as in-person or Skype interviews, will be counted as less than one. Class Structure Class time will be divided into several parts: 1. Group feedback. The group will meet as a whole to reflect on lessons from the week’s interviews. A small number of teams will present their weekly progress report to the entire group. 2. Cohort presentations: Weekly presentations and progress tracking. Each team will present an 8-minute weekly progress report to members of the Teaching Team in their cohort. We will offer observations, suggestions and monitor your progress. When your team is not presenting, each member of your team will be grading your peers. 3. Lecture on next week’s topic: Following the team presentations, each cohort will receive a lecture on the next portion of the Business Model Canvas to prepare you for the week’s interviews. These lectures will be specific to your cohort. Deliverables Meaningful Customer Discovery requires the development of a minimum viable product (MVP). The MVP is defined as follows: 6 1 Therapeutics: Definition of the type and quality of data required for a Biopharma to be interested in a commercial partnership or other collaboration. 2 Digital health: a live website, alpha or beta. Other deliverables are: Weekly LPC narrative. LPC should be updated after every customer interview. Final updates for the week are due by Wednesday noon. Weekly 8 minute team presentation to summarize progress with slides. “Lessons Learned” Presentations -- At the last class, each team will present their “Lessons Learned” to the Teaching Team and invited guests, including investors, in their exploration of commercial feasibility. The presentation includes a PowerPoint summary of Lessons Learned and a 2-minute video explaining your journey’s highlights. Note: Your slides will be public. They should not contain any proprietary information. Mentors Mentorship is an important element for success of a venture and we have assembled a group of experienced mentors to help guide you. Every team will be assigned a mentor who has committed to spending two hours a week for the duration of the class. Our mentors come from the Silicon Valley ecosystem and work with startup ventures, lending their expertise in the “pay it forward” culture we are so fortunate to have in the Bay Area. They will guide you through your learnings from customer interviews. Class Schedule Overview Date Topic January 8 January 15 January 22 January 29 February 5 February 12 February 19 February 26 Business Model Canvas/customer development NO CLASS –LaunchPad Central self-administered training Value Proposition Customer Segments Activities Resources Partners Channels 7 March 5 March 12 March 19 Customer relationships Revenue models and costs; Storytelling Lessons learned Pre-Class Group Meeting Rooms Rooms will be available for meeting before class to allow teams to convene and prepare. Presentation Format Each week’s Powerpoint presentation builds on the prior weeks’ presentations. The following core slides need to appear in every presentation, augmented by content specific to the last week’s Business Model Canvas topic. Core presentation 1. Title slide: your team name, participants, number of interviews completed the past week and in total; interviews broken down by in-person/Skype and phone. 2. What you learned about the week’s topic by talking to customers. Section headings are – What we thought What we did What we found What we’re going to do next 3. Business Model Canvas with changes marked in red. 4. Next week’s plan. Slides listed under each class in the syllabus should be added to the core presentation above. Pre-class preparation Teams are expected to hit the ground running. We assume you and your team have come prepared having read the assigned materials and watched the online lectures. We expect you to have spoken to 5 potential customers before the start of the class to generate findings about your value proposition hypotheses. The best performing teams get a good start and maintain a rapid pace of discovery interviews. Remember that in a startup there is no “spare time.” • Participate in the LaunchPad Central webinar. http://blog.launchpadcentral.com/video-tutorials 8 Online lessons in Udacity: 1 What we now know, 1.5a business models, 1.5b customer development “How to Do Customer Discovery” videos on LaunchPad Central • “How to Do Customer Discovery” videos on Vimeo ,http://vimeo.com/87302754 • CD41 Pre-¬‐Planning: Contacts http://vimeo.com/87303446 • CD42 Customer Interview Dry Runs http://vimeo.com/87302981 • CD44 Pass/Fail Experiments http://vimeo.com/87302754 • CD46 Conducting a Customer Interview http://vimeo.com/87302479 • CD50 Looking for Insights http://vimeo.com/87301695 • CD01 Death By PowerPoint http://vimeo.com/76171146 • CD04 Understanding the Problem http://vimeo.com/76173388 Giff Constable, “12 Tips for Early Customer Development Interviews,” http://giffconstable.com/2012/12/12-tips-for-early-customer-developmentinterviews-revision-3/ Talk to 5 customers to complete your initial Business Model Canvas Record the customer interviews in LaunchPad Central If you’re a therapeutics team, look for IP that could be prior art. Find potential competitors Think about and be prepared to answer in class: Therapeutics Teams What does your Target Product Profile look like? Who can quickly confirm it makes sense? Dhealth Teams What is your revenue model? Who is the customer and why will they use your app? All Teams What is the difference between search and execution? What is a business model versus a business plan? What is the Business Model Canvas? What are the 9 components of the Business Model Canvas? What is a hypothesis? What do we mean by “experiments”? What is Customer Development? What are the key tenets of Customer Development? Presentation for first class. Core slides plus market size -- TAM/SAM/Target market for Years 1-3 9 Weekly Breakdown Class 1: January 8. Business Model Canvas/Customer Development Homework: Osterwalder Value Proposition Canvas http://businessmodelalchemist.com/blog/2012/08/achieve-productmarket-fit-with-our-brand-new-value-proposition-designer.html and http://businessmodelalchemist.com/blog/2012/09/test-your-valueproposition-supercharge-lean-startup-and-custdev-principles.html Online lesson on Udacity. Lesson 2, Value proposition Talk to 10-15 customers. Prepare presentation for next class. Core slides plus Value Proposition Canvas o http://www.businessmodelgeneration.com/downloads/value_proposition_ canvas.pdf o What are the Products/Services, Pain Relievers, Gain Creators? o What MVP you will test? January 15. NO CLASS. LaunchPad Central self-administered training Hands-on team training on key features Creating/updating discovery narrative posts Creating/updating Business Model Canvas Using audio recordings, pictures in interviews Exporting canvas, contacts Making an “Ask” of industry experts, faculty, other teams Creating team profiles & opportunity assessments Class 2: January 22. Value Proposition Homework Online lesson on Udacity. Lesson 3, customer segments. Prepare presentation for next week on customer segments. Core slides plus: How do customers solve their problem today? Does your value proposition solve it? How? • Diagram of Customer workflow • Customer Archetypes -- Draw a diagram 10 • Post discovery narratives on Launchpad Central • Therapeutics teams start v.1 Target Product Profile: include data needed preclinically and clinically to validate your therapeutic • Dhealth teams start storyboard for website Class 3: January 29 Customer Segments Homework • Online lesson 8 – Resources, Activities and Costs Prepare presentation on Activities for next class. Core slides plus: • What did you learn were your critical Activities? o Freedom to operate/IP o Clinical Trials o Quality data o Regulatory approval Customer acquisition • What experiments did you run to validate that these are activities? • Rough diagram of activities and resources/partners needed to accomplish them Class 4: February 5 Activities Homework Prep Presentation for next week on Resources. Core presentation plus: • What are your critical Resources? • Resources should match your critical Activities o Are they resources you already have? o Do you need to acquire or partner with others to get them? o How much will they cost? o What human resources will you need? o What equipment resources will you need? o What financial resources will you need to acquire all these resources? • What experiments did you run to validate that these resources can be acquired? • Rough diagram of activities and resources/partners needed to accomplish them. Class 5: February 12 Resources Homework • Online lesson 7 – Partners Prep Presentation for next week on Partners. Core slides plus: • What were your hypotheses about what partners will you need? 11 Partners should match your critical Resources and Activities o Why do you need these partners and what are risks? o Why will they partner with you? o What’s the cost of the partnership? o Diagram the partner relationships with any dollar flows o What are the incentives and impediments for the partners? • What did you learn about your Partners? • Final diagram of activities and resources/partners needed to accomplish them. Class 6: February 19 Partners Homework • Online lesson 4 – Channels Prepare presentation for next week on Channels. Core slides plus: • What is the distribution channel? Are there alternatives? What was it that made channel partners interested? Excited? • Draw the channel diagram. Annotate it with the channel economics. • Drug startups outline operational plan of pre-clinical and clinical data that drive value. • See Mark Leslie Value Chain slides at http://www.slideshare.net/markleslie01/070801value-chain-and-sales-model • Review Startup Tools: http://steveblank.com/tools-and-blogs-forentrepreneurs/#startup-tools Class 7: February 26 Channels Homework Online lesson 5– Customer Relationships Prepare presentation for next week on customer relationships. Core slides plus: • What were your objective pass/fail metrics for each “Get” test/methodology • Who are the Key Opinion Leaders (KOL’s) • Therapeutics: Who will be on your Scientific Advisory Board (SAB) What conferences do you need to present at? What journals do you need to be in? Who are the Bus Dev people you need to target? Update Target Product Profile and list of top Biopharma prospects with strategic need for your product. • Dhealth: What is your customer acquisition cost? How will you create demand? Build demand creation budget and forecast. 12 Class 8: March 5 Customer Relationships Homework Online lesson 6 – Revenue Models Online lesson ‐ Storytelling. David Riemer, UC Berkeley Haas, http://venturewell.org/i-corps/llpvideos/david-riemer/ o Draw the Get/Keep/Grow diagram -- Annotate it with the key metrics. o Prepare presentation for next week on Revenue Models and Costs. Core slides plus: o What experiments do you run to test your revenue model and pricing? o Diagram of payment flows o Rough three-year income statement to show you have a real business with your revenue model, channel, acquisition costs, etc. o Diagram the finance and operations timeline Class 9: March 12 Revenue Models and Costs; Storytelling Homework Get ready for the Lessons Learned presentation in the last class. Watch previous teams’ final presentations o See http://www.slideshare.net/sblank/ for examples o Review: http://www.slideshare.net/sblank/lessonslearned-day-presentationskills-training • Final 10‐minute presentation and a 2‐minute video Class 10: March 19 Lessons Learned Day Presentation Format Deliverable: Each team will present a 10-minute “Lessons Learned” presentation about their business, plus a 2-minute video summarizing their journey. Incorporate storytelling elements in your presentation. - The World – market/opportunity, how does it operate The Characters – customers/value proposition/ product-market fit, pick a 13 few examples to illustrate Narrative Arc – lessons learned how? Enthusiasm, despair, learning then insight Show us – images and demo to illustrate learning = wireframes & pivots to finished product Editing – does each slide advance the character and plot (learning) Theater Point me at what you want me to see Self-explanatory slides Use analogies Slide 1 – Team name, with a few lines of what your initial idea was and the size of the opportunity Slide 2 – Team members – name, background, expertise and your role on the team Slide 3 – Business Model Canvas v.1. Use the Osterwalder Canvas; do not make up your own. “Here was our original idea.” Slide 4 – “Here’s what we did…” (explain how you got out of the building) Slide 5 – “Here’s what we found - reality, then…” Every presentation requires at least three Business Model Canvas slides. Side n – “Here’s where we ended up.” Talk about: 1. What you learned 2. Whether you think this a viable business, 3. Whether you want to pursue it after the class. Final Slides – Click through each one of your Business Model Canvas slides. Final presentation tips: • You cannot possibly cover everything you learned in 10 weeks during a 10-minute presentation. Don’t try to. The final presentation is partly an exercise in distilling the most critical, surprising, and impactful things you learned in the process. • Don’t fall into the trap of making your final presentation too high-level. If it becomes an overview with no details you will lose the audience and you will look no smarter than you did on Day 1. We need to see WHY your Business Model Canvas evolved the way it did. Include anecdotes about 14 specific customer interviews that support the story you are telling. • If you have a demo, screenshots, a target product profile, etc., include it in your presentation as a supporting character to illustrate your learning and where it has gotten you. We are not just interested in WHAT your product is, but WHY your product is – what did you learn from customers that shaped the product? 2-minute video: Create a video to be shown at the beginning of your final presentation. The video should summarize the Customer Discovery journey your team went on, highlighting the key customer insights that took you from your initial idea to today. Storytelling quality is critical. High production value is not -- some of the best videos have been very straightforward. Make it personal: include the team in the video as well as key "aha" moments. This video is about the discovery process. It is NOT a marketing video. See sample videos here: Bionicks Video, Gutwiser Final Video, Dentometrix Video Teaching Team Bios Core Team Nancy Kamei, Entrepreneur-in-Residence, UCSF School of Pharmacy Nancy, a PharmD from UCSF, is a serial entrepreneur and investor. Nancy started her career at Merck and managed a $1.8m sales territory in suburban/rural Pennsylvania. She completed her MBA at Stanford and then entered the biotechnology industry where she was in sales and later became an Entrepreneur-in-Residence at Institutional Venture Partners. She is a serial entrepreneur - having been on the start-up teams of four successful biotechnology companies: Onyx Pharmaceuticals, Tularik GlycoGen, and ImmuLogic. She has been an analyst/portfolio manager at Capital Group Companies responsible for public equity investments in biotechnology, healthcare services and facilities, and healthcare information technology, later. She transitioned to venture capital at Intel Capital, worked on an investment strategy in Global Health for Aberdare Ventures, and served as the Venture Capital Fellow for the Bill and Melinda Gates Foundation. Stephanie Marrus, Director, Entrepreneurship Center; Lecturer, UCSF; Faculty Bay Area ICorps. Stephanie is responsible for delivering programs and courses enabling scientists and clinicians to create entrepreneurial ventures based on UCSF technologies. She leverages her participation in the Silicon Valley ecosystem to attract resources and 15 entrepreneurship thought leadership to Campus. During a 25-year plus career, she has been a corporate executive, business consultant and mentor with hundreds of companies in science- and technology-based industries, many with their technological roots at MIT, Harvard, the University of California and Stanford. Her consulting clients have included venture capitalists, CEOs, National Science Foundation grantees and foreign government entities. In addition to her business career, she served as Deputy Secretary of Economic Affairs for a Massachusetts governor where she took the lead on economic development and business policy. She has been President of a medical research foundation and serves on the Advisory Board of a social venture startup accelerator. She was faculty at UC Berkeley and has been a guest lecturer at Stanford. Her academic titles have included Entrepreneur-in-Residence at the Lester Center, Haas School of Business, UC Berkeley; Adjunct Professor, St. Petersburg State University Graduate School of Management, Russia; and Entrepreneur-in-Residence, King Abdullah University of Science and Technology, Jeddah, Saudi Arabia. She has guest lectured in Europe, Asia, Latin America and the Middle East. She is on the faculty at the NSF’s Bay Area I-Corps node. She holds an MBA from the Wharton School, University of Pennsylvania, an MA from Columbia University and an AB from Cornell University. Todd Morrill, Faculty Director and Instructor, Bay Area I-Corps Todd has been building and leading bioscience companies since the first biotech boom in the early 1980s. He has been employee number 500, number 10 and number 2 (several times) of venture-backed startups, as well as a founder of three companies. He spent seven years in investment banking for pharma and biotech, and has worked at multinational pharma, diagnostics and tools companies. His roles have included sales, product management, marketing, R&D, business development and CEO. He has been an independent Board member of three biotech companies. Todd taught at the Haas School of Business, UC Berkeley from 2001 to 2009, where he is a Richard C. Holton Teaching Fellow. His courses included Entrepreneurship in Biotechnology; Mergers and Acquisitions; and Entrepreneurship. He has taught in the Intel Program in China and Japan, the Malaysia/UCSF program, and in biotech programs in Estonia, Australia and Abu Dhabi. Todd received an MBA from Haas and his BA in Biology, with Highest Honors, from Dartmouth College. He is an internationally-recognized author of many emails, has received slightly less than one Olympic medal, and a comparable number of Nobel nominations. He is an avid user of social interaction; his teenagers make fun of him on Facebook and his wife makes fun of him in French. He returned to teaching in 2013 because of his excitement with the NSF Innovation Corps (I-corps) program. Cohort Instructors 16 Therapeutics: Karl Handelsman, Founder, Codon Capital Formerly the General Partner Emeritus at CMEA Capital, Karl has a great passion for science and innovation and has been privileged to work alongside many talented entrepreneurs. The management teams at Ambrx, Ensemble Discovery, Ilypsa, Intellikine, Kalypsys, Maxygen, Phenomix, Rigel, Syrrx, Tetraphase, and Xenoport – all have contributed to Karl’s wealth of experience executing visionary plans. Prior to joining CMEA, Karl worked in biotech business development at Millennium. He was one of the first employees of Tularik, and the Whitehead Institute. Digital Health: Chris DeNoia, Advisor DoctorBase Chris has had several business development positions in the dhealth world, most recently as VP Business Development for Amplify Health, where he defined the value proposition and market fit for providers in value based payment models. A Lean LaunchPad convert, he brought LLP to his company and led customer discovery process following Lean Startup methodology for payer opportunities. He was VP Business Development & Sales at Simplee, where he led business development and sales efforts closing deals with Fortune 100 companies, leading HSA administrators, private exchanges, and acute care hospital groups. He wore many hats at the seed level including marketing, operations, security, compliance, etc. --whatever it took to close and implement a deal. He has an MBA from the joint Columbia University/London Business School program. Lynne Chou, Partner, Kleiner Perkins Lynne joined Kleiner Perkins Caufield and Byers in 2013 and focuses on life science investing in medical devices, diagnostics, and digital health. Before joining KPCB, Lynne had over twelve years of healthcare operating and investing experience. Most recently, Lynne worked for eight years at Abbott Vascular and Guidant in multiple roles and worked on the launch of over ten interventional cardiology and cardiac surgery product families both in the US and internationally. Most recently, Lynne lead the global launch of Absorb, the world’s first bio-resorbable vascular scaffold, recognized by Wall Street Journal as Medical Device Technology Innovation of the Year and Popular Mechanics. Lynne was responsible for building the global commercial strategy and therapy development as well as playing a key role in the clinical, reimbursement, operational strategy for the therapy. Earlier in her career, Lynne worked at Apax Partners with a focus on software venture capital investing. In addition, Lynne worked at Goldman Sachs in the Mergers and Acquisitions group and worked on multiple multibillion dollar acquisitions and sell side transactions in various industries. Lynne earned a bachelor of science degree in industrial engineering from Stanford University and an MBA from Harvard Business School. 17 Malay Gandhi, Managing Director, Rock Health Malay serves as Rock Health’s Managing Director, leading the organization and working closely with portfolio companies. He joined Rock Health in 2012 after nearly eight years with Deloitte Consulting’s healthcare practice. Malay earned a Masters concentrated in Health Policy and Management from the University of Pittsburgh and a BS from West Virginia University. His work in digital health has been cited in the Harvard Business Review, Financial Times, CNBC, USA Today, Inc. and KQED. Teaching Assistants Kyra Davis, Program Manager, Entrepreneurship Center at UCSF Kyra.davis@ucsf.edu, (415) 502-1612 Kyra has been at the Entrepreneurship Center since 2012 where she is responsible for executing programs to support doctors and scientists getting ideas out of the lab and into the market. Previously, she raised seed funding and managed an international team as a cofounder of VOZ (www.madebyvoz.com), a company that brings indigenous textiles to the high fashion market. Kyra graduated from UC Berkeley in 2008 and earned a Masters in Management with honors from the London School of Economics, focusing on innovation. Robin Mansukhani, CEO & President, Alzeca Robin Mansukhani is President & CEO of Alzeca Biosciences. Previously, Robin was a founder of Cense Biosciences, which has glucose responsive insulin for type I and type II diabetes and Ecorithm, an energy company. He contributed to the initial founding and/or operation of LivingGreen Materials and Azano Pharmaceuticals. He worked for The Maple Fund, an early stage venture capital firm. He is Co-founder and Chief Operating Officer of BlueStamp Engineering, a New York City and Houston based, hands on engineering program for high school students. He has been an invited speaker both domestically and abroad, including TEDx. Robin holds a B.S. in Biochemistry from Case Western Reserve University. 18