Biologist ___________________________ DNA Timeline Date ______________ Choose one of the following scientists whose research falls somewhere on DNA’s timeline. Briefly describe their significant findings in terms of DNA as well as the year they made their discoveries. 1. Friedrich Miescher 2. Erich Von Tschermak-Seysenegg 3. Thomas Hunt Morgan 4. Barbara McClintock 5. Joshua Lederberg 6. Evelyn Witkin 7. Erwin Chargaff 8. Rosalind Franklin 9. Hershey and Chase 10. Watson and Crick 11. Paul Charles Zamechik and Mahlon Hoagland 12. Author Kornberg 13. Sydney Brenner 14. Craig Venter 15. Oswald Avery 16. Kary Mullis 17. Alec Jeffereys 18. Mario Renato Capecchi 19. Francis Collins 20. John Sulston DNA Timeline Guide 1. Friedrich Miescher – discovery of DNA (1875) 2. Erich Von Tschermak-Seysenegg – rediscovery of mendel’s laws (1908) 3. Thomas Hunt Morgan – genetics of fruit flies (1912) 4. Barbara McClintock – Jumping genes (1931) 5. Joshua Lederberg – conjugating bacteria (1943) 6. Oswald Avery – Transforming factor (1944) 7. Erwin Chargaff – rules for base pairing (1944) 8. Evelyn Witkin – DNA repair (1945) 9. Rosalind Franklin – x ray structure of DNA (1952) 10. Hershey and Chase – blender experiment (1952) 11. Watson and Crick – double helix (1953) 12. Paul Charles Zamechik and Mahlon Hoagland – tRNA (1956) 13. Author Kornberg – DNA (1957) 14. Sydney Brenner – mRNA (1961) 15. Kary Mullis – invented PCR (1982) 16. Alec Jeffereys – Developed DNA fingerprinting (1988) 17. Mario Renato Capecchi – homologous recombination (1989) 18. Craig Venter – human genome (2000) 19. Francis Collins – Human genome (2001) 20. John Sulston – genetic regulation of the cell cycle (2002)