Posters – Infectious diseases and Vaccines NAME OF THE PROJECT NAME OF THE MAIN CONTACT ORGANISATION NAME Translational platform for addressing antibiotic resistance Hilde Revets University of Antwerp - VAXINFECTIO - state-of-the-art high-and medium throughput in vitro biofilm models including microcosm models - clinically relevant animal models of S. aureus infection, namely, pneumonia/VAP and acute endocarditis models for high content discovery compound screening Technology - expertise in studying the mechanism of biofilm and persister formation and the link with virulence and antibiotic resistance - next generation sequencing (NGS) platform to allow rapid identification of bacterial DNA and RNA signatures and use as ‘track-and-trace’ system for antimicrobial resistance - expertise in profiling drug resistance development in animal models upon treatment, as well as biodistribution/tissue penetration and tissue toxicity analyses, thus allowing to characterize the activities at the basis of a therapeutic compound and hereby helping to predict potential side effects and/or failures of the treatment in humans. Customers / Target market Pharma and Biotech companies involved in the development of antimicrobial drugs (incl vaccines) and Medical Device companies Research Institutes involved in research on antimicrobial resistance Industry : Pharma and Biotech Industry Industry and competitors Competitors : currently uniquely positioned as multidisciplinary platform Financing need / Commercial opportunity Looking for: - fee-for-service activities - research contracts IP – Patent situation N/A Future steps / Milestones N/A Further reading N/A Contact person Dr. Hilde Revets, Research and Innovation Manager, Vaccine & Infectious Disease Institute (VAXINFECTIO) – University of Antwerp, hilde.revets@uantwerpen.be