UP Bioresource Paper template Bioresource paper for submission to the Open Journal of Bioresources To complete this template, please replace the blue text with your own. The paper has four main sections: (1) Overview; (2) Methods; (3) Bioresource description; (4) Reuse potential. Please submit the completed paper to: Samuel.moore@ubiquitypress.com (1) Bioresource Overview Title The title of the Bioresource paper should focus on the resource, e.g. “Bioresource on Breast Cancer Patients from X”. If the resource is closely linked to a specific research paper, then “Bioresource from Paper Title” is appropriate. Paper Authors 1. Last name, first name; (Lead/corresponding author first) 2. Last name, first name; etc. Paper Author Affiliations 1. First author affiliation 2. Second author affiliation etc. Abstract A short (ca. 100 word) summary of the bioresource should be described: what it is for, type of sampling and of biospecimens, reuse potential. Project description Give a general aim and description of the project that led to the bioresource creation (200 -300 words with a maximum of 10 key references). Classification (1) Please select from: human, animal, microbial, plant; other Species If non human, please list the species involved in the study, using common and latin names from the IT IS database (http://www.itis.gov), e.g.: Common malaria mosquito, Anopheles quadrimaculatus UP Bioresource Paper template Classification (2) Please select from: biological samples, biological samples and associated data, data only, clinical data, other. Keywords keyword 1; keyword 2; etc (maximum of 5) Context: Spatial coverage (Boundary coordinates can be found using the itouch map tool.) Description: Place names including country, region, town, of where the bioresource was collected: Northern boundary: +/- x.x Southern boundary: +/- x.x Eastern boundary: +/- x.x Western boundary: +/- x.x Temporal coverage The start and end dates of the collection period for the bioresource (dd/mm/yyyy). If the bioresource is ongoing, please give an estimation of the expected date of last inclusion. Temporal coverage for accessibility: Indicate the date by when the bioresource must be destroyed, if applicable. (2) Methods Describe the methods used to collect the bioresource (ca. 100-200 words) using the following sub-headings: Steps The series of procedures undertaken to collect the bioresource (specify which Standard Operating Procedures were used, if applicable, and in which fields SOPs have been implemented: infrastructure, management, ICT; if public information, please specify it…). Stabilization/preservation UP Bioresource Paper template e.g., type of container, type of stabilization, Heparin, on ice… Type of long-term preservation e.g. Formalin-Fixed Paraffin-Embedded (FFPE), frozen, fresh; specify security measures. Storage temperature e.g. -80°C; -20°C Shipping temperature from patient/source to preservation or research use e.g. – 170°C to – 190°C (liquid nitrogen), -80°C (on dry ice); 0-4°C (on ice); room temperature (18-25°C); other, please specify Shipping temperature from storage to research use e.g. – 170°C to – 190°C (liquid nitrogen), -80°C (on dry ice); 0-4°C (on ice); room temperature (18-25°C); other, please specify Quality assurance measures e.g. if a specific norm is followed please state it with its reference for each category of samples (i.e. cells, DNA, RNA, tissue…) Source of associated data e.g. health records, national registries, questionnaires… Ethics Statement: Please indicate any relevant documentation of consent and Institutional Review Board approval, including the name of the board and the date of approval, and any ethical or legal limitations for the collection (in particular, indicate whether biological samples will be destroyed over a specific period of time…) Constraints Please list any constraints involved in bioresource collection (i.e. geographical, regulatory…). (3) Bioresource description Object name The exact name of the object in the biobank. Bioresource name The exact name of the primary bioresource. UP Bioresource Paper template Bioresource acronym or short name (if relevant) Bioresource location The full address of the bioresource (please specify here if the bioresource is part of an Institution and list here if there are other locations, specifiying whether these are duplicate or a unique part of the bioresource). Bioresource contact Please obtain consent if publishing personal email addresses – general email addresses are preferred if they exist, e.g. admin@biobbank.edu Bioresource URL The full web address of the bioresource Identifier used (if available: DOI, etc.) Bioresource type Pathology, Rare Disease type (if applicable), Cytology, Gynecology, Obstetrics, Transfusion, Transplant, Clinical chemistry, IVF and similar, Bacteriology, Virology, Genetic variant, other please specify. Type of sampling Population, family, disease based, longitudinal cohort; sampled in clinical care; sampled in a research protocol; other, please specify. Anatomical site e.g., Right breast Disease status of patients/source e.g. Diabetic Clinical characteristics of patients/source: age, gender, treatment information, inclusion criteria, stage of the disease at time of collection, etc. e.g. pre-menopausal breast cancer patients Size of the bioresource Indicate the number of individuals at present time and, if project is ongoing, the estimated number at the end of the project. UP Bioresource Paper template Vital state of patients/source e.g. postmortem Clinical diagnosis of patients/source e.g., Breast Cancer Pathology diagnosis e.g. Her2-negative intraductal carcinoma; please indicate an international classification code of the disease. Control samples If any, specify the criteria they have been selected on. Biospecimen type e.g. Tissue, ascites, blood, cells, DNA, RNA, serum, plasma, cell lines Please specify the number of aliquots per category and their size/volume Size of the bioresource Indicate the number of individuals at present time and, if project is ongoing, the estimated number at the end of the project. Release date The date (If the bioresource is currently under embargo, please give the date at which it will be made available. Note that you will also need to provide full access to the journal for the purposes of peer review, in full confidentiality). Access criteria As examples, specify the process for applying to samples: is a request form in place, number of samples available, cost to access material and/or data; specify if any, restrictions on access to the bioresource (e.g. access for specific countries or not)… A requirement for publication of the paper is that the bioresource is guaranteed to be made available should these conditions be met. (4) Reuse potential (ca. 50-200 words) Please describe the ways in which the data/samples could be reused by other researchers. Acknowledgements Please list anyone who helped to create the bioresource (who may also not be an author of the paper), including their roles and affiliations. Add any relevant acknowledgements to anyone else who supported the project in which the bioresource was created, but did not work directly on it. UP Bioresource Paper template Funding statement If the bioresource resulted from specific funds, please give the funder and grant number. Author Roles Choose from: Collector of Data or Samples; Bioresource Manager; Director; Creator; Curator; Other (please specify). References Please enter a constrained list of references in the numbered (Vancouver) reference style and include a DOI where available, citing them in the text with a number in square brackets, e.g. [1] [1] Piwowar, H A 2011 Who Shares? Who Doesn't? Factors Associated with Openly Archiving Raw Research Data. PLoS ONE 6(7): e18657. DOI: http://dx.doi.org/10.1371/journal.pone.0018657. Copyright Notice Authors who publish with this journal agree to the following terms: Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal. By submitting this paper you agree to the terms of this Copyright Notice, which will apply to this submission if and when it is published by this journal.