MAGNESIUM DEFICIENCY WHAT DOCTORS ARE SAYING: “It is shocking, frankly, how little people know, how little doctors know, about this vital mineral (magnesium).” -Dr. Jay S. Cohen, MD, author of “The Magnesium Solution for High Blood Pressure” “Without enough magnesium, cells simply don’t work.” -Dr. Lawrence Resnick, MD, Cornell University “Most modern heart disease is caused by magnesium deficiency. A vast and convincing body of research, largely ignored, has convinced us and many colleagues of this fact.” -Dr. Mildred S. Seelig, MD, MPH author of “The Magnesium Factor” “Studies have shown that 90 percent of individuals with type II diabetes have low levels of free intracellular red blood cell magnesium.” -Dr. Zachary T. Bloomgarden, MD, Endocrinologist “The more I learn about magnesium, the more convinced I am that doctors are missing a huge opportunity by not making it one of their drugs of choice.” -Dr. Carolyn Dean, MD, author of “The Magnesium Miracle” “Magnesium is the most important mineral to man and all living things.” -Dr. Jerry Aikawa, The University of Colorado “Research has overwhelmingly demonstrated the critical relationship between low levels of magnesium and cardiovascular disease. So many hypertensive (high blood pressure) patients could benefit from increased intake of this mineral.” -Dr. Julian Whitaker, MD, one of America’s best known doctors of integrative medicine “If magnesium is deficient, bones are more fragile.” -Bones researcher Katherine Tucker, PhD, of Tufts University “Magnesium has solved more ‘incurable’ and ‘mysterious symptoms’ than any other mineral I have observed in 31 years.” -Dr. Sherry Rogers, MD, author of “Depression: Cured at Last” “Magnesium depletion may represent the most frequently unrecognized electrolyte abnormality in clinical practice today. There appears to be as much as an 85 to 95 percent shortfall in the clinical recognition of abnormal serum (blood) magnesium. The role of magnesium in cellular function, both in health and disease, remain largely unknown to medical clinicians.” -Dr. Robert Whang, MD “A link between magnesium, diabetes and hypertension seems established beyond a reasonable doubt.” -Dr. Lawrence Resnick, MD, Cornell University “Magnesium deficiency is one of the most common nutritional problems in the industrialized world today. This deficiency is the result of agricultural practices, food preparation techniques, and dietary trends. The health implications are nothing short of catastrophic.” -Dr. Mark Sircus, Ac, OMD, author of “Transdermal Magnesium Therapy” “For millions of Americans, correcting magnesium deficiency could be one of the most important steps on the road back to health.” -Dr. Alan Gaby- Author of “Magnesium: How an Important Mineral Helps Prevent Heart Attacks and Relieves Stress” Recommended Dosage: Take 400 mg of Magnesium Taurate, Glycerate, Citrate or Chelated (Do not take Magnesium Oxide) with 100mg of B6. Increase dose every 3 days until you have loose bowels then back off 1 dose. RESEARCH STUDIES: Heart Disease and Hypertension A study of over 10,000 people in the United States found that 79% were not consuming the US RDA daily intake of magnesium in their diet. Further, the study showed that 26 percent of the people in the study were taking magnesium supplements and it was this group of people that demonstrated lower levels of C-Reactive protein. Elevated C-Reactive protein is quickly becoming one of the most powerful predictors of heart disease. Source: US study, reported in the July 2006 issue of the journal Nutrition Research. An analysis of seven major clinical studies shows that intravenous magnesium reduced the risk of death by 55% after acute heart attack. These results were published in the prestigious “British Medical Journal” and the widely read journal “Drugs”. Source: Teo KK et al, “Effects of intravenous magnesium in suspected acute myocardial infarction: overview of randomized trials. “Brit Med J, vol. 303, pp. 1499-1503, 1991. In studies of natives from Greenland, the Bantu peoples of Southern Africa, Bedouin people of the Middle East and Aborigines of Australia, incidences of high blood pressure and heart disease were low due to high levels of magnesium in their drinking water and food. When these people moved to urban areas and began eating a modern diet, they developed high blood pressure and heart disease as often as those in the industrialized western countries. Source: Altura, B.M., B.T. “Magnesium and Cardiovascular Biology.” Scientific American, Science & Medicine, May/June 1995: 28-37. In a double-blind, placebo-controlled study, published in the British Journal of Nutrition in 1997, people who took 411- 548 mg of magnesium daily achieved a reduction in both systolic and diastolic blood pressure. Source: Itoh, K., Kawasaki, T., Nakamura, M. “The effects of high oral magnesium supplementation on blood pressure, serum lipids and related variables in apparently healthy Japanese subjects”. British Journal of Nutrition, 1997;78 (5):737-50. In a study of people who are borderline hypertensive, Drs. Burton and Bella Altura, two of the leading researchers in the field of magnesium, report that 70-80% have significantly depressed blood-ionized magnesium levels. Source: Altura, B.M., B.T. “Magnesium and Cardiovascular Biology”. Scientific American, Science & Medicine, May/June 1995:28-37. Diabetes Three of the largest studies ever done on the incidence of disease are the Harvard Nurses’ Health study of 85,000 women, the Health Professionals Follow-up study of 43,000 men, and the Iowa Women’s Health study of 40,000 women. All 3 studies showed that those people with the highest levels of magnesium intake had the lowest risk for developing diabetes. Stroke A study of 98 stroke patients admitted to the emergency room of 3 hospitals in New York exhibited early and significant magnesium- ion deficits. The stroke patients also demonstrated a high calcium to magnesium ratio, which are signs of increased vascular tone and cerebral vessel spasm. Source: Altura BT et al. “low levels of serum ionized magnesium are found in patients early after stroke which result in rapid elevation cytosolic free calcium and spasm in cerebral vascular muscle cells.” Neurosci Lett, vol. 230, no. 1, pp. 37-40, 1997. All deaths due to stroke among Taiwan residents (17,133 cases) from 1989- 1993 were compared with deaths from other causes (17, 133 controls). It was determined that the higher the magnesium levels in drinking water used by Taiwan residents, the lower the incidence of stroke. Source: Yang CY, “Calcium and magnesium in drinking water and risk of death from cerebrovascular disease.” Stroke, vol. 18, no. 8, pp. 411414, 1998. Metabolic Syndrome In a 15 year study of 5,000 young adults, it was found that higher intake of magnesium through food or supplements led to a lower likelihood of developing Metabolic Syndrome. Note: Metabolic Syndrome is characterized as a single person who has several health risk factors at the same time, including abdominal obesity, high cholesterol, high blood pressure, diabetic, etc. Source: He K, Liu K, Daviglus ML, Morris SJ, Loria CM, Van Horn L. Jacobs DR, Savage PJ, “Magnesium intake and the incidence of metabolic syndrome among young adults.” Circulation, vol. 113, no. 13, pp. 1675-1682, 2006 PMS Recent studies showed that of 192 women taking 400mg of magnesium daily for PMS, 95 % experienced less breast pain and had less weight gain, 89% suffered less nervous tension, and 43% had fewer headaches. Source: Goldberg B, Alternative Medicine Guide: Women’s Health Secrets Series 1, Future Medicine Publishing, Tiburon, CA 1998. Depression A study of approximately 500 depressed people by Dr. RH Cox and Dr. CN Shealy found that the majority of the sufferers were magnesium deficient. The authors of the study advised clinicians that they should consider the distinct possibility of therapeutic benefit from the use of magnesium therapy in chronic depression. Source: Cox RH, Shealy CN, Cady RK, Veehoff D, Burnetti Awell M. Houston R, “Significant magnesium deficiency in depression:” J Neurol Orthop Med Surg, vol. 17. Pp. 7-9, 1996. Migraines A group of 3,000 patients given 200mg of magnesium daily had an 80% reduction in their migraine symptoms. Source: Mauskcop A, Fox B, What your doctor may not tell you about migraines, Warner Books, New York, 2001.