ARROW
I. PROTOCOL BASICS
PROTOCOL BASICS
Protocol title
PI name
Protocol renewal
Protocol writer
Email contacts
Emergency contacts
FUNDING
RSP-managed funding
Other funding
PHS finding
PROTOCOL TYPE
Protocol type
VA ACORP
VA ACORP
SIGNIFICANCE AND
JUSTIFCATION AND
INFECTIOUS DISEASE
Significance work
Justify animals
Infectious disease
PROTOCOL OVERVIEW
Experimental summary
DUPLICATION SEARCH
Duplication databases
Duplication years
Duplication recent
Duplication keywords
Duplication other
Duplication narrative
II. SPECIES BASICS
SPECIES SELECTION
Common species
Taxonomic menu
BIOMEDICAL and
AGRICULTURE SPECIES
CONFIRMATION
Species confirmation
SPECIES DETAILS BASIC
BIO / AGRICULTURE
NEW
PAPER
NOTES
Q5
Q1
Q3
x
Q1.
Q1.
Q13
Q13
Q13
Q4
x
Q11a
Q11b
Q16b
~Q17a
New question is more
of a basic overview,
details to be provided
in animal section(s)
Q16a 1
Q16a 1
Q16a 1
Q16a 1
Q16a 1
Q16a 1
Q9a
Q9a
x
Computer driven
necessity
Enter species details
SPECIES APPROPRIATE
Species appropriate
MAXIMUM NUMBERS
Maximum 3-year
Number justify
AGRICULTURAL SPECIES
SOURCE
UW or affiliated sources
Non-UW sources
Transmittable disease
PRIOR USE
Prior use
BREEDING AND
GENETICALLY MODIFIED
SELECTION
Breeding
Genetically modified
BREEDING
Breeding scheme
Breeding excess
GENETICALLY MODIFIED
ANIMALS
GM title
GM complications
GM pain
III. NON SURGICAL
PROCEDURES (SPECIES
DETAILS)
NON-SURGICAL
PROCEDURE SELECTION
Non-surgical selection
BLOOD COLLECTION
Blood read
Blood exceed
Blood justify
FOOD AND/OR FLUID
REGULATION
FFR title
FFR describe
FFR justify
FFR monitor
IMAGING
Imaging table
IRRADIATION EXTERNAL
x
Computer driven
necessity
Q11c
Q9a, Q12
Q12
Q9a
Q9a
x
9c
Q17a
x
Q17a
x
x
x
x
Q17a
Q17a
x
x
Q17c
Q17c
Q17c
Q17c
Q17a
SOURCE
Irradiation table
PHYSICAL RESTRAINT
Restraint table
SUBSTANCE
ADMINISTRATION
Substance table
 cells, cell lines, tissues, or
tissue products (animal
and/or human)
 complete Freund’s
adjuvant (CFA)
 Controlled substances
(requiring DEA
registration)
 Non-pharmaceuticalgrade compounds


Paralytic agents
Select Agents or Toxins
(as regulated by CDC,
DHHS or USDA)
OTHER NON-SURGICAL
PROCEDURES
Other non-surgical
NON-SURGICAL
MONITORING
Non-surgical monitoring
IV. SURGICAL
PROCEDURES (SPECIES
DETAILS)
SURGICAL PROCEDURES
Surgery y/n
SURGICAL SUMMARY
Surgery table
Surgery monitor
Recovery monitor
Surgery pain
CONCURRENT SURGICAL
PROCEDURES
Concurrent surgery
MULTIPLE SURVIVAL
SURGERIES
x
Q17a
Q17b
Q17a
x
x
x
Q17a
Q27b
x
Q17a
Q18 and Q19
Q7a
Q26, Q27a, &
Q28a
Q27a
Q29
Q29
x
Not specifically in
current paper
question but asked
during protocol
review
Multiple surgeries
V. ALTERNATIVE SEARCH
(SPECIES DETAILS)
ALTERNATIVES SEARCH
Alternative databases
Alternative years
Alternative recent
Alternatives other
Alternative strategy
Alternatives narrative
VI. COMPLICATION
(SPECIES DETAIL)
COMPLICATIONS
Complications
USDA DESIGNATION
USDA Designation
VII. ENDPOINTS AND
EUTHANASIA (SPECIES
DETAILS)
EUTHANASIA
Planned euthanasia criteria
Unplanned euthanasia
criteria
Euthanasia anticipated
Euthanasia unanticipated
Nonstandard euthanasia
justify
Ensure death
DISPOSITION
Disposition
Consumption
VIII. NON STANDARD
HUSBANDRY (SPECIES
DETAILS)
NON-STANDARD
HUSBANDRY
Non-standard husbandry

Lab staff provide
husbandry in lab housing
x
This question is
subtly different than
Q30 in the old form.
Now asks about
multiple surgeries not
just multiple major
surgeries.
Q16a2
Q16a2
Q16a2
Q16a2
Q16a2
Q16a2
x
x
Q19 and Q20
Q19 and Q20
Q21
Q21
x
Q21
Q22
Q23
Q17d
x
Some new stuff in this
question

Lab staff provide
husbandry in facility
 Single housing of social
species
 Enrichment withholding
 Exercise withholding in
dogs
 Ambient noise
 Nonstandard lighting
 Vibration
 Cleaning/ sanitation
schedule different than
facility standard
 Enclosure smaller or
denser than standard for
species
 High velocity air
 Bare floor (no bedding)
with no structure for
resting or sleeping
 Wire bottom cage with
NO resting platform
(rodent only)
 Temperature outside
recommended range
 Other nonstandard
housing or husbandry
IX. LOCATIONS AND
TRANSPORT (SPECIES
DETAILS)
HOSING AND PROCEDURE
LOCATION SELECTION
Locations
x
Enter any locations not
found above
PROCEDURE LOCATION
SELECTION
Location table
TRANSPORT
Transport routes
Transport methods
Departmental vehicle
Personal vehicle
X. PERSONNEL
x
x
x
Q17d
x
Q17d
x
Q17d
Q17d
x
x
x
x
x
Q8, Q10, and
Q25
x
x
x
x
x
Computer driven
necessity
STUDY TEAM
Study team
Study team additional
PI oversight
TRAINING
Study team member
procedure assignment
XI. OCCUPATIONAL
HEALTH
OCCUPATIONAL HEALTH
AND SAFETY OF
PERSONNEL
Occupational hazards
 Biological hazards
 Chemical hazards
 General hazards
 Physical hazards
 Radiation, radioactive
materials
 Recombinant materials
XIII. PI SIGNATURE
FINISH PROTOCOL
Q15 & Q24
x
Computer driven
necessity
x
Q15 & Q24
Q16b & Q16c
Q16b & Q16c
Q16b & Q16c
x
x
Q16b & Q16c
Q16b & Q16c
x