Grade 11 Test questions practice _ SL 1. DNA is made up of three components: deoxyribose, phosphate and bases. What is the maximum number of components that deoxyribose is linked to in a DNA molecule? a. One phosphate and one base b. Two phosphate and one base c. One phosphate and two bases d. Two phosphates and two bases 2. What is replicated by a semi-conservative process? a. mRNA only b. mRNA and tRNA only c. mRNA, tRNA and DNA d. DNA only 3. In which process is tRNA involved? a. Recombinatino b. Replication c. Transcription d. Translation 4. What causes the two DNA molecules formed by replication to have the same base sequence as the original molecule? a. Helicase b. RNA polymerase c. Complimentary base pairing d. Mitosis 5. The genetic code is degenerate. What does this mean? a. It is not universal b. The code is not stable c. It contains both codons and anticodons d. There is more than one codon for some amino acids 6. What is the arrangement of nucleotides in a single DNA strand? S = sugar, P = phosphate, B = organic base 7. Which group of three molecules makes up one RNA nucleotide? a. Phosphate, ribose, uracil b. Phosphorous, ribose, adenine c. Uracil, deoxyribose, phosphorous d. Guanosine, deoxyribose, phosphate 8. Outline a technique for transferring genes between species (5) 9. Describe the roles of mRNA, tRNA and ribosomes in translation (6) 10. Which property of the genetic code allows the transfer of genetic material between species? a. Helical b. Degenerate c. Universal d. Non-overlapping 11. The diagram below represents a DNA nucleotide. What could the part labelled X represent? a. b. c. d. Ribose Uracil Guanine Phosphate 12. In the bacterium Escherichia coli the DNA can be replicated at nearly 2000 base pairs per second. Human DNA is replicated at more than 5 million base pairs per second. Why is the replication of human DNA so much faster? a. Human cells have a higher concentration of DNA nucleotides in their cytoplasm b. Human cells have a faster form of DNA polymerase c. Human cells operate at a higher temperature d. Human cell DNA replication starts at several points simultaneously 13. Where is an anti-codon located? a. tRNA b. mRNA c. DNA d. Ribosomes 14. Outline the structure of DNA. (5) 15. Explain the process of transcription in eukaryotes (8) 16. a. Draw the structure of a generalized dipeptide (4) b. Explain the process of translation leading to peptide linkage formation (8 17. In the structure of DNA what binds with cytosine? a. Deoxyribose b. Ribose c. Thymine d. Adenine 18. a. Determine the strand of mRNA that is transcribed from the DNA strand below (1) A–T–C–C–A–G–G–T–C–A–A–G b. List three of the other molecules, apart from mRNA, required for transcription. (3) 19. The following diagram represents replication in DNA. a. State the name and describe the function for the enzymes labelled A and B on the diagram. (2) i. A: Name: Function: ii. B: Name: Function: b. Identify the cellular location of DNA replication in eukaryotic cells (1) c. State at which period during the cell cycle DNA replication occurs (1) d. Explain the significance of complementary base pairing during DNA replication (2) 20. During the process of replication, which bond(s) in the diagram of DNA below is/are broken? a. b. c. d. 3 4, 5 1, 2, 6, 7 1, 7, 4, 5 21. The drawing below shows a short section of a DNA molecule. What is labelled by I, II and III? A B C D 22. I 3’ end 5’ end 3’ end 5’ end II Purine Pyrimidine Pyrimidine Purine III Hydrogen bond Covalent bond Hydrogen bond Covalent bond a. State two differences between the structure of DNA and RNA (2) The diagram below shows the structure of a ribosome during protein synthesis b. State the names of the structures labelled above (2) I: II: III: IV: c. State the name of a structure shown on the diagram that has an anticodon. (1) d. Explain why the process used during protein synthesis in cells is called translation. (2) e. Explain briefly how termination of translation occurs (2) 23. If a polypeptide consists of 240 amino acids, what is the minimum number of nucleotides needed on the sense strand of a gene to code for it? a. 80 b. 240 c. 720 d. 1440 24. Draw and label a simple diagram showing how DNA nucleotides are linked together in a single strand. (4) 25. Outline the significance of complementary base-pairing in DNA, you may find it useful to reference the work of Meselson & Stahl (5)