NATIONAL AUDIT PROJECT 6
Perioperative Anaphylaxis
Churchill House 35 Red Lion Square London WC1R 4SG
020 7092 1677 nap6@rcoa.ac.uk
ADDITIONAL NOTES FOR ALLERGY CLINICS
NAP6 2015-16
The Royal College of Anaesthetists is conducting a National Audit Project (NAP6) over a 1 year period from November
2015.
NAP6 is supported by AAGBI, BSACI, RCP/RCPath Joint Committee on Allergy and Immunology, MHRA, Allergy UK and
Anaphylaxis Campaign.
NAP6 will encompass service evaluation and audit. No patient-identifiable data will be collected.
NAP6 will collect case-by-case information relating to the management and investigation of patients with suspected
perioperative anaphylaxis across the UK. Data, including the outcome of subsequent investigations, will be uploaded
securely by a Local Coordinator anaesthetist in each UK hospital, working closely with the anaesthetist who was
involved in the immediate management of the suspected anaphylactic event. Cases will be reviewed by a
multidisciplinary panel, unaware of the identity of the patient or the allergy clinic.
The information provided by allergy clinics to the referring clinician will be central to the collection of complete and
accurate information. The NAP6 Steering Panel would be grateful if your clinic letter could make particular reference to
the following:




Receipt of mast cell tryptase results from the referring clinician
All skin test results (positive and negative)
Results of all other allergy/hypersensitivity investigations
An indication of your level of confidence in your diagnosis (recognising that the degree of certainty may be less than
“high” due, for example, to missing clinical information or a patient declining further testing)
 Your advice concerning future anaesthesia
 Whether a hazard-warning application form was provided to the patient in clinic
The findings of NAP6 will be published in anaesthesia and allergy journals with appropriate acknowledgements.
For any queries relating to NAP6, please contact NAP6@rcoa.ac.uk
This page should be included with the completed AAGBI referral proforma when patients with suspected perioperative
anaphylaxis are referred to an allergy clinic for investigation.
Sixth National Audit Project of the Royal College of Anaesthetists: Perioperative Anaphylaxis
Anaesthetic Anaphylaxis Referral Form
Patient details
Name……………………………………………………………....................................
Date of birth
Address
…./…./……..
Hospital / NHS Number ………………………….
………….………………………………………………………...................
………………………………………………………
Telephone …………………
Referring clinician (address for correspondence)
Name…………………………………………………………………...
Address…………..………….…………………………………………
………………………………………………………………………….
Telephone…………………… Fax: ……………………. Email ……………………
Anaesthetist (if different from above)
Name…………………………………………………………………...
Address…………..………….…………………………………………
………………………………………………………………………….
Telephone…………………… Fax: ……………………. Email ……………………
Patient’s GP
Name…………………………………………………………………...
Address…………..………….…………………………………………
………………………………………………………………………….
Telephone…………………… Fax: ……………………. Email ……………………
Surgeon
Name…………………………………………………………………...
Address…………..………….…………………………………………
………………………………………………………………………….
Telephone…………………… Fax: ……………………. Email ……………………
NATIONAL AUDIT PROJECT 6
Date of the reaction …./…./……..
Time of onset of reaction …./….h (24h clock)
Perioperative Anaphylaxis
Suspected cause of the reaction
Churchill House 35 Red Lion Square London WC1R 4SG
020 7092 1677 nap6@rcoa.ac.uk
1) ……………………….. 2) …………………..…… 3) ……………………..…
Proposed surgical procedure:……………………………………..
Was surgery completed?
Yes □ No □
If ‘no’, has another date for surgery being scheduled? Yes □ No □
Urgency of future surgery.……………………………………………………………...
Details of the reaction
Symptom/ Sign
Onset Time
Time resolved
(24 h clock)
Severity (Mild/Moderate/Severe)
(24 h clock)
Hypotension
Lowest BP
Tachycardia
Bradycardia
Bronchospasm
Cyanosis/
desaturation
Angioedema
Urticaria
Arrhythmia
Flushing
Itching
Other (specify)
Lowest SpO2
/
mmHg
NATIONAL AUDIT PROJECT 6
Drugs administered BEFORE the onset of the reaction. In addition, please include time of
tracheal intubation, LMA insertion, and any other relevant event
Perioperative Anaphylaxis
Drug/Procedure
Time over which
Churchill House 35 Red Lion Square Londonadministered
WC1R 4SG
020 7092 1677 nap6@rcoa.ac.uk
(‘STAT’ or in min:sec)
Time
(24 hr
clock)
Route
Intravenous fluids given BEFORE the onset of the reaction with approximate start times
1.
2.
3.
…………………..
..…………………
…………………..
_____:_____
_____:_____
_____:_____
Drugs given AFTER the onset of the reaction
Drug / Fluid
Time over which administered
(‘STAT’ or in min:sec)
Time
(24 hr
clock)
Route
NATIONAL AUDIT PROJECT 6
Perioperative Anaphylaxis
Churchill House 35 Red Lion Square London WC1R 4SG
020 7092 1677 nap6@rcoa.ac.uk
Intravenous fluids given AFTER the onset of the reaction with approximate start times
1.
2.
3.
4.
…………………..
..…………………
…………………..
…………………..
_____:_____
_____:_____
_____:_____
_____:_____
Comments on response to treatment
…………………………………………………………………………………………..…………………
………………………………………………………………………..
Outcome
Survived:
Yes □
No □
Transfer to:
Ward □ HDU □ ICU □ Other …………………………………
Anaesthetic techniques and procedures.
Yes □
Latex free environment?
No □
Central venous access
Time: ……h
Skin prep ……………………… Type of CVC ……………………
Was a coated catheter used?
Yes □
No □
Neuraxial blockade
Spinal □ Epidural □
Epi-spinal □ Skin Prep……………………………..
NATIONAL AUDIT PROJECT 6
Perioperative Anaphylaxis
Drug/Procedure
Time over which
administered
Churchill House 35 Red Lion Square London WC1R 4SG
(‘STAT’ or in min:sec)
020 7092 1677 nap6@rcoa.ac.uk
Time
(24 hr
clock)
Route
Peripheral nerve blockade
Type of block(s) :…………………………
Skin Prep ……………………
Drugs given for peripheral nerve blockade.
Drug
Time over which
administered
(‘STAT’ or in min:sec)
Time
(24 hr
clock)
Urethral catheterisation
Time ………h
Antiseptic solution …………………………………. …...
Urethral lubrication/local anaesthetic.………………………………………….
Type of catheter (eg latex, silastic etc)…………………………………………
Skin preparation for surgery and start of surgery
Time skin preparation ………………h Skin Prep ………………………………….
Time surgery commenced: ………....h
Time surgery completed …………… h
Route
NATIONAL AUDIT PROJECT 6
Perioperative Anaphylaxis
Investigations performed prior to referral (please give results if known)
Churchill House 35 Red Lion Square London WC1R 4SG
020 7092 1677 nap6@rcoa.ac.uk
Were blood samples taken for Mast Cell Tryptase measurement?
First sample
Second sample
Time___:___
Time___:___
Third sample
Yes □
No □
Date___/___/____ Result………….
Date___/___/____ Result……….....
Time___:___
Date___/___/____ Result………….
Other bloods tests:
Test:…………………Time___:___Date___/___/____ Result………………………
Test:…………………Time___:___Date___/___/____ Result………………………
N.B. It is the anaesthetist’s responsibility to obtain the results from the laboratory
Case discussed at a multidisciplinary meeting? Yes □
Reported to the MCA? Date___/___/____
No □
By whom? ……………………………………
Please send the completed form to the specialist investigation clinic together with:

Photocopy of the anaesthetic record and any previous anaesthetic records

Photocopy of the prescription record

Photocopy of the recovery-room documentation

Photocopy of any relevant ward documentation
Please file a copy of this form in the patient’s casenotes and keep a copy for your own records.