CURRICULUM VITAE
DR. MUHAMMAD AJMAL
Personal Data:
Father’s Name: Chaudhry Muhammad Ashraf
Date and Place of Birth: 31 st Dec 1975, Gujrat, Pakistan
Nationality:
Mailing Address:
Home Address:
Pakistani
Department of Bio Sciences,
COMSATS Institute of Information Technology
Park Road, Chak Shahzad, Islamabad
Ch. M. Hanif Street No. 1, Nai Abadi, Dhoke Gujran,
Mobile:
Email:
Near Iqbal Masjid, Chakra Road, Rawalpindi
+92 300 5347366 chmajmal@gmail.com
, muhammad.ajmal@comsats.edu.pk
Present Position:
Senior Scientific Officer, Department of Bio Sciences, COMSATS Institute of Information
Technology, Park Road, Chak Shahzad, Islamabad, Pakistan, since 27 th
June 2013.
Previous Experience:
Administrator PCR Laboratories, Shifa College of Medicine, Shifa Tameer-e-Millat University,
Sector H-8/4, Islamabad, From 14 th
February 2005 to 15 th
August 2013 (8
½
Years).
Academic Record:
Ph.D. (Molecular Genetics), 2013 Netherlands
M.Phil. (Molecular Biology/Biochemistry),
M.Sc. (Biochemistry),
2005
2001
Pakistan
Pakistan
B.Ed. (Biology, chemistry),
B.Sc. (Botany, Zoology and Chemistry),
F.Sc. (Pre-Medical),
Matric (Science),
1998
1995
1994
1991
Pakistan
Pakistan
Pakistan
Pakistan
PhD Thesis: “Genetic Basis of Inherited Eye Diseases”. Online link to access PhD thesis:
(http://repository.ubn.ru.nl/bitstream/2066/106926/1/106926.pdf)
M. Phil Thesis: “Genetic Mapping of The Candidates of Hereditary Deafness Genes”.
M.Sc. Research Report: “Correlation of Serum Cholesterol and Sugar with Age and Gender”.
Conferences and courses attended:
Real Time PCR Workshop held on 12 th
Aug 2005 at Shifa College of Medicine, Islamabad
Pakistan, conducted by BioFlux Corporation, Tokyo, Japan.
BICMAPE Conference held from 28 th
Jul 2009 to 29 th
Jul 2009 at COMSATS Institute of
Information Technology, Abbottabad, Pakistan.
Eye Genetics Course: (Bologna, Italy) (28 th
Sep 2011 to 1 st
Oct 2011).

NGS Course: Genomic resequencing: variant detection and interpretation in a diagnostic context (Nijmegen, Netherlands) (4 th
Apr 2012 to 5 th
Apr 2012).
Dutch Ophthalmology PhD Students (DOPS) conference: (Nijmegen, Netherlands) (13 th Apr
2012 to 14 th
Apr 2012).
Publications:
1.
Ajmal M , Khan MI, Neveling K, Khan YM, Azam M, Waheed NK, Hamel C, Ben-Yosef
T, De Baere E, Koenekoop RK, Collin RWJ, Qamar R, Cremers FPM. Exome sequencing identifies a DHX38 missense mutation associated with severe early-onset retinitis pigmentosa in a Pakistani family: a new RNA splicing gene defect associated with a macular coloboma. ( Manuscript in preparation ).
2.
Khan MI, Ajmal M , Hussain A, Shah STA, Micheal S, Ali SHB, Waheed NK, Khan YM,
Bokhari H, Collin RWJ, den Hollander AI, Qamar R, Cremers FPM, Azam M. Genetic causes of retinal dystrophies in Pakistan. ( Manuscript in preparation ).
3.
Shafique S, Siddiqi S, Schraders M, Oostrik J, Ayub H, Bilal A, Ajmal M , Seco CZ, Strom
TM, Mansoor A, Mazhar M, Shah STA, Hussain A, Azam M, Kremer H, Qamar R. Genetic
Spectrum of Autosomal Recessive Non-Syndromic Hearing Loss in Pakistani Families.
( Manuscript in preparation ).
4.
Cremers FPM, den Dunnen JT, Ajmal M , Hussain A, Preising MN, Daiger SP, Qamar R .
Comprehensive Registration of DNA Sequence Variants Associated with Inherited Retinal
Diseases in Leiden Open Variation Databases. Hum Mutat . (2013); (In press). doi:
10.1002/humu.22458. Impact Factor = 5.213
5.
Ajmal M , Khan MI, Neveling K, Tayyab A, Jaffar S, Sadeque A, Ayub H, Abbasi NM,
Riaz M, Micheal S, Gilissen C, Ali SHB, Azam M, Collin RWJ, Cremers FPM, Qamar R.
Exome sequencing identifies a novel and a recurrent BBS1 mutation in Pakistani families with Bardet-Biedl syndrome. Mol Vis 2013; 19:644-653. Impact Factor = 1.987
6.
Ahmad W, Whittal RA, Riaz M, Putt W, Ajmal M , Sadeque A, Ayub H, Qamar R,
Humphries SE. The genetic spectrum of familial hypercholesterolemia in Pakistan. Clinica
Chimica Acta 2013; 421:219-225. Impact Factor = 2.850
7.
Khan MI, Ajmal M , Micheal S, Azam M, Hussain A, Shehzad A, Venselaar H, Bokhari H, de Wijs IJ, Hoefsloot LH, Gill M, Waheed NK, Collin RWJ, den Hollander AI, Qamar
R, Cremers FPM. Homozygosity mapping identifies genetic defects in four consanguineous families with retinal dystrophy from Pakistan. Clin Genet 2013; 84 (3):290-293.
Impact
Factor = 4.247
8.
Ajmal M , Khan MI, Neveling K, Khan YM, Ali SHB, Ahmed W, Iqbal MS, den Hollander
AI, Collin RWJ, Qamar R, Cremers FPM. Novel mutations in RDH5 cause fundus albipunctatus in two consanguineous Pakistani families. Mol Vis 2012; 18:1558-
1571. Impact Factor = 1.987
9.
Ajmal M , Khan MI, Micheal S, Ahmed W, Shah A, Venselaar H, Bokhari H, Azam A,
Waheed NK, Collin RWJ, den Hollander AI, Qamar R, Cremers FPM. Identification of

recurrent and novel mutations in TULP1 in Pakistani families with early onset retinitis pigmentosa. Mol Vis 2012; 18:1226-1237. Impact Factor = 1.987
10.
Ahmed W, Ajmal M , Sadeque A, Whittall RA, Rafiq S, Putt W, Khawaja A, Imtiaz F,
Ahmed N, Azam M, Humphries SE, Qamar R. Novel and recurrent LDLR gene mutations in
Pakistani hypercholesterolemia patients. Mol Biol Rep 2012; 39(7):7365-7372. Impact
Factor = 2.506
11.
Satti R, Mustafa F, Khan MI, Haq TS, Khan ZU, Zubair M, Rasool STU, Azam M, Ajmal
M , Qamar R. Prevalence of Hepatitis C Virus in Urban Ghettos of Twin Cities. Pakistan J
Zool 2012; 44(4):937-943. Impact Factor = 0.309
12.
Ajmal M , Ahmed W, Akhtar N, Sadeque A, Khalid A, Ali SHB, Ahmed N, Azam M,
Qamar R. First report of a nonsense triple nucleotide polymorphism (TNP) in the low density lipoprotein receptor gene in familial hypercholesterolemia. Genet Test Mol
Biomarkers 2011; 15(9):601-606. Impact Factor = 1.444
13.
Azam M, Collin RWJ, Malik A, Khan MI, Sadeque A, Shah STA, Shah AA, Hussain
A, Ajmal M , Arimadyo K, Cremers FPM, Qamar R, den Hollander AI. The genetic basis of retinitis pigmentosa in Pakistan. Archiv Opthalmol 2011; 129(10):1377-1378. Impact
Factor = 3.826
14.
Ahmed W, Malik M, Khan AA, Saeed I, Sadeque A, Kaleem U, Ajmal M , Azam M, Qamar
R. Role of tissue plasminogen activator (t-PA) and plasminogen activator inhibitor (PAI-1) polymorphism in Myocardial Infarction. Mol Biol Rep (2011): 38(4):2541-2548. Impact
Factor = 2.506
15.
Ajmal M , Ahmed W, Sadeque A, Ali SHB, Bokhari SH, Ahmed N, Qamar R. Identification of a recurrent insertion mutation in the LDLR gene in a Pakistani family with autosomal dominant hypercholesterolemia. Mol Biol Rep (2010).37(8): 3869-3875. Impact Factor =
2.506
16.
Ayub H, Khan MI, Micheal S, Akhtar F, Ajmal M , Shafique S, Ali SHB, den Hollander AI,
Ahmed A, Qamar R. Association of eNOS and HSP70 gene polymorphisms with glaucoma in Pakistani cohorts. Mol Vis (2010);16:18-25. Impact Factor = 1.987
17.
Azam M, Collin RWJ, Khan MI, Shah STA, Qureshi N, Ajmal M , den Hollander AI,
Qamar R, Cremers FPM. A novel mutation in GRK1 causes Oguchi disease in a consanguineous Pakistani family. Mol Vis 2009; 15:1788-1793. Impact Factor = 1.987
Total Impact Factor of 14 published research papers = 35.342

References:
1.
Prof. Dr. Frans P.M. Cremers
Department of Human Genetics, Radboud University Medical Centre, Geert Grooteplein
10, 6525 GA, Nijmegen, the Netherlands.
Tel: +31-24-3613750, Cell: +31-6-23738881, Email: frans.cremers@radboudumc.nl
2.
Prof. Dr. Raheel Qamar
Dean, Office of Research, Innovation and Commercialization, COMSATS Institute of
Information Technology, Park Road, Chak Shahzad, Islamabad, Pakistan.
Tel: +92-51-9247000 ext 5036, Cell: +92 321 5119494 Email: drraheel@gmail.com
3.
Dr. Rob W.J. Collin
Department of Human Genetics, Radboud University Medical Centre, Geert Grooteplein
10, 6525 GA, Nijmegen, the Netherlands.
Tel: +31-24-3613750, Email: rob.collin@radboudumc.nl