OIE Collaborating Centre Reports
Activities in 2013
Title of Collaborating Centre:
Address of Collaborating Centre:
Emerging and Re-emerging
Zoonotic Diseases
National Center for Emerging and Zoonotic Infectious
Diseases (NCEZID)
Centers for Disease Control and Prevention
1600 Clifton Road, MS D-76
Atlanta, Georgia 30333
Tel.:
(1-404) 639.7378
Fax:
(1-404) 639.7090
e-mail address:
website:
Name of Director of Institute
(Responsible Official):
chr1@cdc.gov
http://www.cdc.gov/ncezid
Beth Bell, MD, MPH
Name (including Title and
Position) of Head of the
Collaborating Centre (formally
OIE Contact Point):
Carol Rubin, DVM, MPH
Director, One Health Office
Name (including Title and
Position) of writer of this report
(if different from above)
Rebekah Kunkel, MS, MPH
ORISE Fellow, One Health Office
Annual reports of OIE Reference Centres, 2013
1
Emerging and Re-Emerging Zoonotic Diseases
Summary of activities specifically related to the mandate of
OIE Collaborating Centres
ToR:
To provide services to the OIE, in particular within the region, in the designated
specialty, in support of the implementation of OIE policies and, where required, seek for
collaboration with OIE Reference Laboratories
ToR:
To identify and maintain existing expertise, in particular within its region
1.
Activities as a centre of research, expertise, standardisation and dissemination of
techniques within the remit of the mandate given by the OIE
Disease control
Epidemiology, surveillance, risk assessment, modelling
Training, capacity building
Zoonoses
Wildlife
Avian diseases
Aquatic animal diseases
Animal welfare
Diagnosis, biotechnology and laboratory
Veterinary medicinal products
Vaccines
Food safety
Feed safety
Other (Name the category:
)
DISEASE CONTROL
2
Title of activity
Scope
Rabies control
Enhanced efforts to control global canine rabies through continued incountry consultations, diagnostic support, training, and health education to
ministries of agriculture and health representatives.
Sterilizing waste using solar
power
Partnered with CDC-Kenya and a non-governmental organization
(Sanivation) to use concentrated solar energy to sterilize waste so it can be
safely used for fertilizer or fuel.
Identification of viral
hemorrhagic fever outbreaks
In conjunction with the Uganda Virus Research Institute, assisted in the
testing and identification Ebola hemorrhagic fever infection (Luwero
District of central Uganda) and Marburg virus infection (Kabale, Ibanda,
Mbarara, and Kampala Districts of Uganda).
Anthrax outbreak preparation
and investigation in Azerbaijan
and Georgia
Temporary duty support and intensive planning for 2013 Anthrax Seasonal
Outbreaks in Azerbaijan and Georgia, including enhanced surveillance and
public awareness
Multiagency task force for
response to rabies outbreaks
Worked with Nigeria’s Federal Ministry of Health, Ministry of Agriculture,
the National Veterinary Research Institute to create protocols for response
to rabies outbreaks; guidelines for post-exposure prophylaxis use
Improving refugee health
through treatment of parasitic
infections
Provide treatment for parasitic infections to US-bound refugees
populations in Thailand, Malaysia, Nepal, Ethiopia, and Kenya.
Annual reports of OIE Reference Centres, 2013
Emerging and Re-Emerging Zoonotic Diseases
EPIDEMIOLOGY, SURVEILLANCE, RISK ASSESSMENT, MODELLING
Title of activity
Scope
MicrobNet
MicrobeNet, a reference database for infectious pathogens, was released
on January 1, 2013. It enables multiple analyses of a new or rapidly
emerging pathogen and reduces reporting time. Laboratory scientists
throughout the world can run diagnostic tests and match results against
unique or rare isolates in CDC’s reference collections.
ArboNET
ArboNET is a network for mosquito-borne disease detection, prevention,
and control. ArboNET funding assists states, Puerto Rico, and six large
municipalities to conduct case investigations, field collections, and analyses
and submission of information to rapidly monitor and respond to potential
epidemic conditions.
TickNET
TickNET works with state health departments to optimize surveillance and
prevention activities for bacterial tick-borne diseases, such as Lyme disease
and Rocky Mountain spotted fever. A study of the effectiveness of home
pesticide use is under way through TickNET, addressing critical questions
about the prevention of Lyme disease.
CryptoNet
Began pilot testing for CryptoNet, the first state-based molecular tracking
system for a parasitic infection, cryptosporidiosis. CryptoNet will help us
better understand the spread of cryptosporidiosis in the United States.
Expand surveillance in-country
for viral hemorrhagic fever
Enabled the rapid diagnosis of Ebola hemorrhagic fever in Uganda by
expanding surveillance in-country for viral hemorrhagic fever (VHF)— a
group of diseases that include Ebola and Marburg hemorrhagic fevers. The
expanded program included assigning a staff member to the Uganda Virus
Research Institute (UVRI), providing training for case recognition and
management for health professionals, providing reagents and training for
diagnostic testing, and completing renovation of the VHF diagnostic
laboratory at UVRI.
Released the report, “Antibiotic
Resistance Threats in the
United States, 2013”
The first comprehensive analysis of the 18 most serious drug resistant
threats that each year sicken more than 2 million people and kill at least
23,000. The report ranks the threats in categories: urgent, serious, and
concerning.
Surveillance of emerging and
re-emerging infectious diseases
in agricultural communities in
Chiang Mai and Nakorn
Ratchasima provinces
Specimens from hospitalized patients with fever of uncertain etiology are
tested for endemic zoonoses. If the etiological agent is zoonotic, a
veterinary team is sent to investigate the disease among animals around
the participants’ farm or house.
Epidemiology and etiology of
flaccid paralysis of infectious
origin in the Republic of Georgia
A prospective hospital-based surveillance to identify cases of acute flaccid
paralysis in adults and children, and characterize the clinical, laboratory,
and electrodiagnostic features of the syndrome
TRAINING, CAPACITY BUILDING
Title of activity
Scope
Epidemiology and Laboratory
Capacity Program
Awarded funding to secure an excellent public health workforce, robust
surveillance systems, and modern laboratory facilities and information
networks and to support disease-specific infectious disease programs in
states. The program supports 50 state health departments, 6 local health
departments, and 8 territories or US affiliates.
Emerging Infections Program
Awarded funding to conduct gold standard surveillance and
epidemiological research to evaluate the impact of prevention programs
Annual reports of OIE Reference Centres, 2013
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Emerging and Re-Emerging Zoonotic Diseases
and policies. The program supports 10 state health departments and their
partners.
Electronic Laboratory Reporting
Provided funding to advance electronic laboratory reporting from clinical
and public health laboratories to public health agencies is helping to
increase national implementation of this technology.
Training for enhanced
laboratory-based surveillance
for monkeypox in the
Democratic Republic of Congo
Providing training for enhanced laboratory-based surveillance for
monkeypox in the Democratic Republic of Congo (DRC). As a result, DRC
has been sending monthly disease reports with laboratory samples for
confirmation so that disease transmission dynamics can be better
understood and to provide evidence for new disease control efforts.
Rabies control in the Republic
of Georgia
Clearance and installation of Lab equipment; scheduling of lab training;
shipment of samples
Strengthening One Health
collaboration in Thailand
The goal of this project is to enable the Bureau of Epidemiology and
collaborating partners to develop disease surveillance, prevention and
control system in line with One Health concepts and to develop an
integrated management system for emerging infectious disease
preparedness and emergency response.
Improving diagnostic capacity
for Q fever and rickettsial
diseases
This study provides the necessary reagents and laboratory support to
establish laboratory diagnostic capacity in Thailand through the Thai
National Institute of Health, the National Institute of Animal Health, and
selected clinical diagnostic laboratories.
Building capacity for zoonotic
endocarditis in Thailand
In collaboration with Khon Kaen University Hospital, Pasteur Institute of Ho
Chi Minh City in Vietnam, and with in-country public health scientists and
clinicians in SE Asia, the project is establishing and improving diagnostic
capacity for C. burnetii, Bartonella spp., and Streptococcus suis.
Development of improved
surveillance, laboratory
capacity for the detection of
zoonotic pathogens at the
Human-Animal Interface in
Thailand
Providing laboratory diagnostic training, laboratory workgroup meetings
and consultative meetings with Department of Livestock Development and
other in-country partners for joint livestock, wildlife and public health
surveillance and investigation of Q fever in Chiang Mai and Nakhon
Ratchasima provinces.
Anthrax surveillance and
prevention measures in
endemic areas in Bangladesh
Refining, standardizing, and strengthening anthrax outbreak responses in
both humans and animals; and building laboratory capacity to enhance
laboratory confirmation of cases.
Surveillance and outbreak
response to Japanese
encephalitis virus in India
Improving capacity for Acute Encephalitis Syndrome surveillance and
outbreak response.
Technical assistance for rabies
outbreaks in Guatemala
Technical assistance to strengthen national laboratory capacity for Rabies
surveillance and outbreak investigation.
One Health curriculum
recommendations
Developed recommendations and training materials for One Health
curriculum as a template for use by for applied epidemiology training
programs
Promotion of Lassa fever
prevention and control
Trained residents in the Nigeria Field Epidemiology and Laboratory Training
Program in the prevention and control of Lassa fever
ZOONOSES
4
Title of activity
Scope
Identification of a novel
poxvirus in the Republic of
Georgia
Collaborated with public health officials in the Republic of Georgia to
investigate the discovery of a new poxvirus that caused infection in
shepherds in Akhmeta, Georgia. Testing by NCEZID’s Poxvirus Laboratory
Annual reports of OIE Reference Centres, 2013
Emerging and Re-Emerging Zoonotic Diseases
found a new poxvirus belonging to the same genus (Orthopoxvirus) as
smallpox.
Maintains a bat breeding colony
Maintains a breeding colony of wild-caught fruit bats from Uganda that is a
resource to understand reservoir host and virus dynamics, including viral
shedding, mechanisms or virus transmission, and host immune response to
Marburg virus
Pathogen discovery
Tested for viruses in over 700 bat and rodent samples collected from
multiple international study sites.
Circulation of Crimean-Congo
hemorrhagic fever virus among
humans, animals, and vectors at
a camel market in Egypt
Assessing the prevalence of Crimean-Congo hemorrhagic fever virus among
high-risk camel owners, domestic and imported camels, and specific
variants of Crimean-Congo hemorrhagic fever virus among ticks collected
from domestic and imported camels.
Bartonella prevalence in cats
and humans in Guatemala
Study to determine the prevalence of Bartonella spp. circulating in cats and
persons at risk (veterinarians, vet technicians, caretakers, etc.) in
Guatemala.
Brucellosis incidence in Kenya
Examining brucellosis incidence in Kajiado, Kenya which is a high risk
county
Assessment of novel and
existing diseases in bats in
Nigeria
Identified novel flaviviruses and pegiviruses in bats
Human and domestic animal
exposure to zoonotic diseases
in bats during the Idanre bat
festival
Assessed human knowledge, attitudes, and behaviors of rabies and other
bat diseases; assessed human and domestic animal illness pre- and postparticipation in the bat festival; performed serological testing of acute and
convalescent specimens in humans and domestic animals
DIAGNOSIS, BIOTECHNOLOGY, AND LABORATORY
Title of activity
Scope
Biotechnology Core Facility
Uses state-of-the-art methods to help CDC researchers study infectious
agents
Plague Rapid Test
Developed a rapid, inexpensive, point-of-care bedside diagnostic ‘dipstick’
test for plague
Rabies direct rapid
immunohistochemical test
Developed a new diagnostic test for rabies that requires no specialized
equipment or refrigeration, and allows a diagnosis to be made in less than
1 hour. The test is as reliable as the gold standard test and only requires a
light microscope.
Cryptococcus screening test
Using a new point-of-care dipstick screening test to detect the presence of
cryptococcal antigen and provide treatment before meningitis develops.
New assay that rapidly detects
fungal DNA in patients
Developed a new diagnostic assay for identifying fungal DNA in patients in
2 days.
Laboratory Response Network
The Laboratory Response Network links 160 highly specialized laboratories,
including health department laboratories, federal and military laboratories,
environmental testing and diagnostic veterinary laboratories, as well as
international laboratories. This unique network of laboratories is designed
to respond to bioterrorism, chemical terrorism, and other public health
emergencies.
Point-of-care assay to diagnose
monkeypox and
orthopoxviruses
The poxvirus team has developed an assay for monkeypox virus and
orthopoxviruses. The assay performs clinical sample nucleic acid extraction
and quantitative analysis within an hour.
Annual reports of OIE Reference Centres, 2013
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Emerging and Re-Emerging Zoonotic Diseases
Division of Scientific Resources
consultation
The Division of Scientific Resources provides expertise to develop and apply
modern technologies (such as genomic sequencing) that result in faster
identification of bacteria, viruses, fungi, and other pathogens.
VACCINES
Title of activity
Scope
Livestock vaccine against Rift
Valley Fever
Developed a recombinant vaccine against Rift Valley fever virus for use in
livestock
Dengue candidate vaccine that
targets all four dengue viruses
Developed a dengue candidate vaccine that targets all four dengue viruses.
The vaccine candidate that is being evaluated in Puerto Rico, Singapore,
Thailand, and Colombia for safety and immunogenicity.
FOOD SAFETY
Title of activity
Scope
Estimates of food sources
associated with foodborne
illness
In January 2013, published the first-ever estimates of food sources
associated with foodborne illnesses in the United States. Produce, including
leafy green and vine-stalk vegetables as well as fruits and nuts, accounts for
about half of all foodborne illness, with norovirus being the most common
cause. The analysis also showed that meat and poultry are the food sources
most often linked to deaths caused by food poisoning, mostly due to
Salmonella and Listeria.
The Global Foodborne
Infections Network
Enhancing foodborne illness surveillance and outbreak response in
conjunction with the World Health Organization
ToR:
To propose or develop methods and procedures that facilitate harmonisation of
international standards and guidelines applicable to the designated specialty
2.
Proposal or development of any procedure that will facilitate harmonisation of
international regulations applicable to the surveillance and control of animal diseases,
food safety or animal welfare
Proposal title
Scope/Content
Applicable area
Collaborating for
the
Implementation
of the Revised
International
Health
Regulations
National
Surveillance and
Response
Capacity
NCEZID works with CDC’s Division
of Global Disease Detection and
Emergency Response to assure that
the IHR process will be
accommodated during all
investigations, surveillance
activities, and research when
appropriate. Whenever possible,
animal and human components are
sharing biologic isolates and
epidemiologic data to facilitate the
control and containment of
disease.
Surveillance and control of animal diseases
The network is a collaboration
between WHO, CDC, and other
international public health
organizations which promotes
integrated, laboratory-based
surveillance and fosters
Surveillance and control of animal diseases
Global
Foodborne
Infections
Network
6
Food safety
Animal welfare
Food safety
Animal welfare
Annual reports of OIE Reference Centres, 2013
Emerging and Re-Emerging Zoonotic Diseases
Proposal title
Scope/Content
Applicable area
intersectoral collaboration among
human health, veterinary and foodrelated disciplines to enhance the
capacity of countries to detect,
respond to and prevent foodborne
diseases.
ToR:
To establish and maintain a network with other OIE Collaborating Centres designated
for the same specialty, and should the need arise, with Collaborating Centres in other
disciplines
ToR:
To carry out and/or coordinate scientific and technical studies in collaboration with
other centres, laboratories or organisations
3.
Did your Collaborating Centre maintain a network with other OIE Collaborating Centres
(CC), Reference Laboratories (RL), or organisations designated for the same specialty, to
coordinate scientific and technical studies?
Yes
Name of OIE CC/RL/other
organisation(s)
No
Location
Region of
networking
Centre
Purpose
The United States Agency
for International
Development’s Emerging
Pandemic Threats
Program
Uganda
Africa
Americas
Asia and Pacific
Europe
Middle East
To assess the risk from emerging zoonotic
pathogens through:
1) Surveillance for acute febrile illness,
especially in high risk locations; 2)
development of affordable point-of-care
tests and local lab capacity to rule-out
endemic diseases; 3) training of national and
local staff in laboratory testing; and 4)
identifying newly emerged pathogens.
The United States Agency
for International
Development’s Emerging
Pandemic Threats
Program
Uganda
Africa
Americas
Asia and Pacific
Europe
Middle East
To build capacity for national viral
hemorrhagic fever surveillance through
ultiple activities to determine the distribution
of viral hemorrhagic fever viruses and the
risks they pose to the human population. Also
working to build viral hemorrhagic fever
laboratory capacity at the Uganda Virus
Research Institute
The United States Agency
for International
Development’s Emerging
Pandemic Threats
Program
Uganda
Africa
Americas
Asia and Pacific
Europe
Middle East
To detect lyssaviruses in wildlife and
determine the environmental, socioeconomical, and medical factors that may be
significantly associated with zoonotic disease
transmission, outbreaks, and human
fatalities. To develop community-appropriate
strategies for reducing human/domestic
animal/ wildlife exposure risks from zoonotic
agents and to enhancement of laboratory
diagnostic capacity
Annual reports of OIE Reference Centres, 2013
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Emerging and Re-Emerging Zoonotic Diseases
Name of OIE CC/RL/other
organisation(s)
4.
Location
Purpose
The United States Agency
for International
Development’s Emerging
Pandemic Threats
Program
Democratic
Republic of
Congo
Africa
Americas
Asia and Pacific
Europe
Middle East
To identify potential modes of transmission
between animals and humans, identification
of potential host species, and determination
of the baseline prevalence of orthopoxviruses
in native mammals in the region.
The United States Agency
for International
Development’s Emerging
Pandemic Threats
Program
Democratic
Republic of
Congo
Africa
Americas
Asia and Pacific
Europe
Middle East
To detect lyssaviruses in wildlife and
determine the environmental, socioeconomical, and medical factors that may be
significantly associated with zoonotic disease
transmission, outbreaks, and human
fatalities. To develop community-appropriate
strategies for reducing human/domestic
animal/ wildlife exposure risks from zoonotic
agents and to enhancement of laboratory
diagnostic capacity
The United States Agency
for International
Development’s Emerging
Pandemic Threats
Program
Indonesia
Food and Agriculture
Organization of the United
Nations
Kenya
CDC’s Rabies Laboratory,
which is an OIE Reference
Laboratory for rabies
Multiple
Africa
Americas
Asia and Pacific
Europe
Middle East
To establish a national reference lab for the
identification of endemic and novel vectorborne viruses
Africa
Americas
Asia and Pacific
Europe
Middle East
Africa
Americas
Asia and Pacific
Europe
Middle East
To initiate a national canine rabies
elimination program modeled after the
progressive control program used in other
livestock diseases
Provides a variety of laboratory services
related to rabies, including diagnostic and
reference services; lab training for health
departments, domestic/international
organizations; collaboration with the private
sector to develop and evaluate diagnostic
assays and vaccines; and microbiology,
molecular biology, and pathogenesis
research
Did your Collaborating Centre maintain a network with other OIE Collaborating Centres,
Reference laboratories, or organisations in other disciplines, to coordinate scientific and
technical studies?
Yes
Name of OIE CC/RL/other
organisation(s)
United States Department of
Agriculture’s Centers for
Epidemiology and Animal
Health
8
Region of
networking
Centre
No
Location
United
States
Region of
networking Centre
Africa
Americas
Asia and Pacific
Europe
Middle East
Purpose
Participates in the U.S. Federal
Interagency One Health Workgroup to
coordinate projects related to One
Health
Annual reports of OIE Reference Centres, 2013
Emerging and Re-Emerging Zoonotic Diseases
ToR:
To place expert consultants at the disposal of the OIE.
5.
Did your Collaborating Centre place expert consultants at the disposal of the OIE?
Yes
No
Name of expert
Kind of consultancy
Subject
Aron Hall
Scientific expert
MERS-CoV
Ruben Donis
Scientific expert
Influenza
Darin Carroll
Scientific expert
Rabies
Many other experts available at OIE’s request for consultation, including (but not limited to)
epidemiologists, laboratorians, ecologists, veterinarians, microbiologists, and virologists
ToR:
To provide, within the designated specialty, scientific and technical training to personnel
from OIE Member Countries
6.
Did your Collaborating Centre provide scientific and technical training, within the remit of
the mandate given by the OIE, to personnel from OIE Member Countries?
Yes
No
If the answer is yes, please provide the total number of trained persons for each of the following
categories:
a)
Technical visits: ................................................................ >10
b)
Seminars: ......................................................................... >10
c)
Hands-on training courses: .............................................. >10
d)
Internships (>1 month): ................................................... >10
Type of technical
training provided
(a, b, c or d)
Content
Country of origin of the
expert(s) provided with
training
No. participants from
the corresponding
country
c
Scientists from Thailand National
Institute of Animal Health and
National Institute of Health
travelled to Atlanta for training on
the analysis of human, animal and
environmental samples for C.
burnetii. CDC scientists also visited
Thailand for additional on-site
training.
Thailand
3
c
Participants from the ministries of
health, animal health and private
universities (University del Valle de
Guatemala and Universidad de San
Carlos de Guatemala, Facultad de
Medicina Veterinaria y Zootecnia)
were provided hands-on experience
in DRIT and DFA testing techniques.
Jan 28th-Feb 1st, 2013.
Guatemala
>10
Annual reports of OIE Reference Centres, 2013
9
Emerging and Re-Emerging Zoonotic Diseases
Type of technical
training provided
(a, b, c or d)
b
Content
Country of origin of the
expert(s) provided with
training
No. participants from
the corresponding
country
Guatemala
>10
A workshop on interagency
coordination for rabies surveillance
outbreak support, conducted in
collaboration with Vets Without
Borders
CDC provides a variety of scientific and technical training to both member and non-member countries.
ToR:
To organise and participate in scientific meetings and other activities on behalf of the
OIE
7.
Did your Collaborating Centre organise or participate in the organisation of scientific
meetings on behalf of the OIE?
Yes
National/
International
International
No
Title of event
Co-organiser
Date
(mm/yy)
Location
No.
Participants
OFFLU Swine Influenza
Virus Group Meeting
OIE, FAO
04/13
Rome
1
ToR:
To collect, process, analyse, publish and disseminate data and information relevant to
the designated specialty
8.
Publication and dissemination of any information within the remit of the mandate given by
the OIE that may be useful to Member Countries of the OIE
(Indicate in the appropriate box the number by category)
a)
Articles published in peer-reviewed journals: .................
Select examples:
Rubin C, Myers T, Stokes W, Dunham B, Harris S, Lautner B, et al. Review of Institute of Medicine
and National Research Council recommendations for One Health initiative. Emerg Infect Dis. 2013
Dec. http://dx.doi.org/10.3201/eid1912.121659
Rubin CS and the Stone Mountain Planning Committee. Operationalizing One Health: Stone
Mountain and beyond. In One Health: The Human-Animal-Environment Interfaces in Emerging
Infectious Diseases. ed. by Mackenzie, Jeggo, Daszak and Richt. December 2013 CTMI;366: 173185.
Algren DA, Monteilh CP, Punja M, Schier JG, Martin Belson M, Hepler BR, Schmidt CJ, Miller CE,
Patel M, Paulozzi LJ, Straetemans M, Rubin C. Fentanyl-associated Fatalities Among Illicit Drug
Users in Wayne County, Michigan (July 2005–May 2006). Journal of Medical Toxicology; 2013
Mar;9(1):106-15.
Gargano LM, Engel J, Gray GC, Howell K, Jones TF, Milhous WK, Rubin C et al. Arbovirus diseases,
southeastern
United
States.
Emerg
Infect
Dis
[Internet].
2013
Nov.
http://dx.doi.org/10.3201/eid1911.130650
10
Annual reports of OIE Reference Centres, 2013
Emerging and Re-Emerging Zoonotic Diseases
Rabinowitz PM, Kock R, Kachani M, Kunkel R, Thomas J, Gilbert J, Rubin C. Toward proof of concept
of a One Health approach to disease prediction and control. Emerg Infect Dis [Internet]. 2013 Dec.
http://dx.doi.org/10.3201/eid1912.130265
Islam A, Mikolon A, Mikoleit M, Dilruba A, Khan SA, Sharker MA, Hossain JM, Islam A, Epstein J,
Zeidner N, Luby SP. Isolation of Salmonella virchow from a fruit bat (Pteropus giganteus).
Ecohealth. 2013 Oct 18. [Epub ahead of print].
Nahar N, Uddin M, Sarkar RA, Gurley ES, Uddin Khan MS, Hossain MJ, Sultana R, Luby SP. Exploring
pig raising in Bangladesh: implications for public health interventions. Vet Ital 2013;49(1):7-17.
Sazzad HM, Hossain MJ, Gurley ES, Ameen KM, Parveen S, Islam MS, Faruque LI, Podder G, Banu
SS, Lo MK, et al. Nipah virus infection outbreak with nosocomial and corpse-to-human
transmission, Bangladesh. Emerg Infect Dis 2013;19(2):210-7.
Haider N, Khan SU, Sarkar S, Poh M, Wilson A, Beckwith N, Azad AK, Paul SK, Rahman MZ, Balish A,
et al. Unusual waterfowl mortality due to highly pathogenic avian influenza A/H5N1 in Bangladesh.
Health and Science Bulletin (icddr,b) 2013;11(1):15-20.
Nakazawa, Y, Lash RR, Carroll DS, Damon IK, Karem KL, Reynolds MG, Osorio JE, Rocke TE, Malekani
JM, Muyembe J-J, et al. Mapping monkeypox transmission risk in the Congo Basin. PLoS One; 2013;
8(9).
Quan PL, Firth C, Conte JM, Williams SH, Zambrana-Torrelio CM, Anthony SJ, Ellison JA, Gilbert AT,
Kuzmin IV, Niezgoda M, et al. Bats are a major natural reservoir for hepaciviruses and pegiviruses.
Proc Natl Acad Sci U S A. 2013 Apr 22. [Epub ahead of print]
Morales-Betoulle ME, Komar N, Panella, NA, Alvarez D, López MR, Betoulle JL, Sosa SM, Müller ML,
Kilpatrick AM, Lanciotti RS, et al. West Nile virus ecology in a tropical ecosystem in Guatemala. Am
J Trop Med Hyg 2013; 88(1):116-26.
Quan PL, Firth C, Conte JM, Williams SH, Zambrana-Torrelio CM, Anthony SJ, Ellison JA, Gilbert AT,
Kuzmin IV, Niezgoda M, et al. Bats are a major natural reservoir for hepaciviruses and pegiviruses.
Proc Natl Acad Sci USA 2013 Apr 22 [Epub ahead of print, doi:10.1073/pnas.1303037110].
Tao Y, Shi M, Conrardy C, Kuzmin IV, Recuenco S, Agwanda B, Alvarez DA, Ellison JA, Gilbert AT,
Moran D, et al. Discovery of diverse polyomaviruses in bats and the evolutionary history of the
Polyomaviridae. J Gen Virol 2013 Apr; 94(Pt 4):738-48.
Feikin DR, Njenga MK, Bigogo G, Aura B, Gikunju S, Balish A, Katz MA, Erdman D, Breiman RF.
Additional diagnostic yield of adding serology to PCR in diagnosing viral acute respiratory infections
in Kenyan patients 5 years of age and older. Clin Vaccine Immunol. 2013 Jan;20(1):113-4. doi:
10.1128/CVI.00325-12. Epub 2012 Oct 31.
Fuller JA, Njenga MK, Bigogo G, Aura B, Ope MO, Nderitu L, Wakhule L, Erdmann DD, Breiman RF,
Feikin DR. Association of the CT values of the real time PCR of viral upper respiratory tract infection
with clinical severity, Kenya. J Med Virol 2013;85(5):924-32.
Knobel DL, Maina AN, Cutler SJ, Ogola E, Feikin DR, Junghae M, Halliday JEB, Richards AL, Breiman
RF, Cleaveland S, et al. Coxiella burnetii in humans, domestic ruminants, and ticks in rural Western
Kenya. Amer J Trop Med Hyg 2013 Mar;88(3):513-8. PMID 23382156
Murray EL, Khagayi S, Ope M, Bigogo G, Ochola R, Muthoka P, Njenga MK, Odhiambo F, Burton D,
Laserson KF, et al. What are the most sensitive and specific sign and symptom combinations for
influenza in patients hospitalized with acute respiratory illness? Results from western Kenya,
January
2007-July
2010.
Epidemiol
Infect
2013
Jan;141(1):212-22.
doi:
10.1017/S095026881200043X. Epub 2012 Mar 15.
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Emerging and Re-Emerging Zoonotic Diseases
Quan PL, Firth C, Conte JM, Williams SH, Zambrana-Torrelio CM, Anthony SJ, Ellison JA, Gilbert AT,
Kuzmin IV, Niezgoda M, et al. Bats are a major natural reservoir for hepaciviruses and pegiviruses.
Proc Natl Acad Sci 2013 May 14;110(20):8194-9. doi: 10.1073/pnas.1303037110. Epub 2013 Apr
22.
Carroll SA, Towner JS, Sealy TK, McMullan LK, Khristova ML, Burt FJ, Swanepoel R, Rollin PE, Nichol
ST. Molecular evolution of viruses of the family Filoviridae based on 97 whole genome sequences. J
Virol 2013;87:2608-2616.
Crabtree, M, Kading, RC, Mutebi J-P, Lutwama, J, Miller, BR. Identification of host blood from
engorged mosquitoes collected in western Uganda using cytochrome oxidase I gene sequences. J
Wildlife Dis 2013 Jul;49(3):611-26.
Graham CB, Borchert JN, Black WC, Atiku LA, Mpanga JT, Boegler KA, Moore SM, Gage KL, Eisen RJ.
Blood meal identification in off-host cat fleas (Ctenocephalides felis) from a plague-endemic region
of Uganda. Am J Trop Med Hyg 2013 Feb;88(2):381-9.
Kading RC, Borland E, Cranfield M, Powers A. Seroprevalence of alphaviruses and flavivirues in freeranging game animals and non-human primates in the Congo Basin. Manuscript in press, J Wildlife
Dis 2013 Jul;49(3):587-99.
b)
International conference presentations: ......................... >30
Select examples:
Title: Human monkeypox in a conflict region of the Democratic Republic of the Congo
Speaker: Andrea McCollum, PhD, CDC/NCEZID/DHCPP
Conference: ASTMH 62nd Annual Meeting
Title: Effective control of Aedes aegypti using CDC autocidal gravid ovitraps
Speaker: Roberto Barrera, CDC/NCEZID/DVBD
Conference: ASTMH 62nd Annual Meeting
Title: Epidemiology of Q fever in Thailand
Speaker: Pawin Padungtod, CDC
Conference: ASTMH 62nd Annual Meeting
Title: Enhancing health care worker capabilities to detect and care for patients with monkeypox
Speaker: Jennifer Bass, CDC/NCEZID/DHCPP
Conference: ASTMH 62nd Annual Meeting
Title: A filovirus marathon: epidemiological and laboratory responses to two outbreaks of Marburg
and Ebola hemorrhagic fever, Uganda, October-November 2012
Speaker: Barbara Knust, CDC/NCEZID/DHCPP
Conference: ASTMH 62nd Annual Meeting
Title: Cluster investigation of melioidosis cases reveals evidence of endemicity in Puerto Rico
Speaker: Thomas Doker, CDC/NCEZID/DHCPP
Conference: ASTMH 62nd Annual Meeting
Title: Establishment and successes of the Uganda National Viral Hemorrhagic Fever Surveillance
Program and High-Containment Laboratory, 2010-2013
Speaker: Trevor Shoemaker, CDC
Conference: ASTMH 62nd Annual Meeting
Title: Re-emergence of Bundibugyo virus after a five year hiatus—Isiro, the Democratic Republic of
the Congo, 2012
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Emerging and Re-Emerging Zoonotic Diseases
Speaker: Ilana Schafer, CDC/NCEZID/DHCPP
Conference: ASTMH 62nd Annual Meeting
Title: Culture-Independent Diagnostics Testing: The End of Surveillance for Foodborne Infections?
Speaker: John Besser, PhD, Deputy Chief, Enteric Diseases Laboratory Branch CDC/NCEZID/DFBMD
Conference: International Association for Food Protection (IFAP) Annual Meeting, Charlotte, North
Carolina 7/29/2013
Title: Pilot protocol for assessment of health needs and evaluation of public health interventions for
U.S.-bound refugees from Burma (Myanmar): Early data
Speakers: Tarissa Mitchell, Centers for Disease Control and Prevention, NCEZID/DGMQ/IRMHB
Conference: North American Refugee Health Conference, June 6, 2013, Toronto, Canada.
Title: Estimating the Public Health Burden of Lyme Disease in the United States
Speaker: Paul Mead, CDC/NCEZID/DVBD
Conference: 13th International Conference on Lyme Borreliosis and Other Tick-Borne Diseases
Title: Metabolic Biomarkers and Biosignatures for Improved Diagnosis of Lyme Disease
Speaker: Claudia Molins, CDC/NCEZID/DVBD
Conference: 13th International Conference on Lyme Borreliosis and Other Tick-Borne Diseases
Title: Efficacy of a Single Peridomestic Application of Acaricide To Prevent Lyme and Other Tickborne Diseases
Speaker: Alison Hinckley, CDC/NCEZID/DVBD
Conference: 13th International Conference on Lyme Borreliosis and Other Tick-Borne Diseases
Title: Update on Emerging Vector-Borne Diseases in the United States
Speaker: Lyle Petersen, MD, MPH, CDC/NCEZID/DVBD
Conference: IDWeek 2013
Title: The whole yellow fever iceberg: Estimating the incidence of infection from the number of
severe cases
Speaker: Michael Johansson
Conference: Fourth International Conference on Infectious Disease Dynamics
c)
National conference presentations: ................................ >50
Select examples:
Title: Foodcore: Foodborne Diseases Centers for Outbreak Response Enhancement - Improving
Foodborne Disease Outbreak Response Capacity in State and Local Health Departments
Speaker: Jennifer Mitchell, CDC/NCEZID/DFWED
Conference: 2013 Annual CSTE Conference
Title: Food Safety Centers of Excellence: Building State and Local Capacity for Foodborne Illness
Surveillance and Outbreak Response
Speaker: Dale Morse, CDC/NCEZID/DFWED
Conference: 2013 Annual CSTE Conference
Title: Epidemiology of Rare But Life-Threatening Diseases: How to Improve Surveillance and Support
for Free-Living Ameba Infections
Speaker: Jennifer Cope, CDC/NCEZID/DFWED
Conference: 2013 Annual CSTE Conference
Title: Turtlepocalypse: Seven Overlapping Multistate Outbreaks of Human Salmonella Infections
Associated With Small Pet Turtles — U.S.A., 2012
Speaker: Maroya Walters, CDC/NCEZID/DFWED
Conference: 2013 Annual CSTE Conference
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Emerging and Re-Emerging Zoonotic Diseases
Title: Mass Human Exposure to Bats at a Volunteer Lodging Facility in Kentucky
Speaker: Ryan Wallace, CDC/NCEZID/DHCPP
Conference: 2013 Annual CSTE Conference
Title: An International Outbreak of Tetracycline-Resistant Salmonella I 4,[5],12:I:- Infections
Associated With Frozen Feeder Rodents Used as Reptile Feed —2008-2012
Speaker: Jennifer Wright, CDC/NCEZID
Conference: 2013 Annual CSTE Conference
Title: Global Foodborne Infections Network (GFN): An opportunity for capacity-building in enteric
diseases in India
Speaker: Nirali Desai, MPH , CDC/NCEZID/DFWED
Conference: 141st APHA Annual Meeting and Exposition
Title: Epidemiology, Sampling and Traceback Working Synergistically
Speaker: Karen Neil, Medical Epidemiologist CDC/NCEZID
Conference: National Environmental Health Association, Annual Educational Conference &
Exhibition (July 10, 2013), Washington, DC.
Title: The trouble with Turtles: Public Health and Regulatory Challenges with Recent Multistate
Outbreaks
Speaker: Stacey Bosch, DVM, MPH, DACVPM Commander, United States Public Health Service
Epidemiologist, Outbreak Response and Prevention Branch CDC/NCEZID/DFWED
Conference: Association of Public Health Laboratories InFORM 2013 Conference, San Antonio,
Texas. November 19, 2013
Title: Backyard Flocks and Salmonellosis: A Growing Public Health Concern
Speaker: Casey Barton Behravesh MS, DVM, DrPH, DACVPM, Deputy Branch Chief, Outbreak
Response and Prevention Branch, DFWED Coordinator for Enteric Zoonoses and One Health Division
of Foodborne, Waterborne and Environmental Diseases, CDC/NCEZID/DFWED
Conference: Association of Public Health Laboratories InFORM 2013 Conference, San Antonio,
Texas. November 19, 2013
Title: CDC Activities on Lyme and other Tick-Borne Diseases
Speaker: C. Ben Beard, Ph.D. Chief, Bacterial Diseases Branch CDC – Division of Vector Borne
Disease, NCEZID, Associate Director for Climate Change
Conference: Report on Tick-Borne Disease and Integrated Pest Management Conference 2013
Arlington, VA March 5-6, 2013
Title: Identification and Promotion of Effective IPM Tools to Reduce Tick-borne Diseases
Speaker: Joe Piesman, Ph.D., CDC Chief of Tick-Borne Disease Activity Bacterial Diseases Branch CDC
– Division of Vector Borne Disease, NCEZID, Associate Director for Climate Change
Conference: Report on Tick-Borne Disease and Integrated Pest Management Conference 2013
Arlington, VA March 5-6, 2013
Title: Evaluating National Estimates of Access to Improved Water Sources and Basic Sanitation as a
Predictor of Epidemic and Endemic Cholera, 1991 to 2010
Speaker: Bejamin Nygren, Epidemiologist CDC/DHHS/CDC/OID/NCEZID/DFWED/WDPB
Conference 2013 Water and Health Conference: Where Science Meets Policy October 14-18
University of North Carolina at Chapel Hill (October 16th)
Title: Access to water, sanitation and hygiene in Artibonite, Haiti: results from an assessment of
rural households and water sources 16- months after the onset of cholera
Speaker: Katharine Schilling, Health Scientist Epidemiologist
CDC/DHHS/CDC/OID/NCEZID/DFWED/WDPB
Conference 2013 Water and Health Conference: Where Science Meets Policy October 14-18
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Emerging and Re-Emerging Zoonotic Diseases
University of North Carolina at Chapel Hill (October 16th)
d)
Other: ...............................................................................
(Provide website address or link to appropriate information)
_______________
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