REGENERATIVE MEDICINE: FROM BASIC RESEARCH TO ORTHOPAEDIC APPLICATIONS AND BEYOND. Chairs of the sessions are expected to introduce the speakers and guide the discussion at the end of the round table. Lunes 25 Martes 26 Miércoles 27 Jueves 28 9:30-11:30 9:30-11:30 9:30-11:30 9:30-11:30 ROUND TABLE: Basic aspects ROUND TABLE: Cartilage cells ROUND TABLE: MSCs in bone regeneration. Chair: and regeneration. Chair: Yrjö production. Chair: Rosaria Nuria Vilaboa. Konttinen Giordano. 10:00-10:30 Official opening: EGB, YTK, Javier Arias (Vice Directorate General of research on Cell Therapy and Regenerative Medicine, Ministry of Science and Innovation), Javier Llorca (Dean, Cantabria Medical School), José Antonio Rodriguez Montes (Dean, UAM Medical School) 9:30-10:00 Stem cells for bone reconstruction. Overview. Gabriela Ciapetti Istituto Ortopedico Rizzoli, Bologna, Italy 10:30-10:50 Overall view on the orthopaedic needs for regenerative medicine. Enrique Gomez-Barrena egbarrena@telefonica.net Spain 10:20-10:40 Adult bone marrow and umbilical cord blood stem cells in experimental critical bone defects and nonunions Viorel Nacu nacu_viorel@yahoo.com 10:50-11:05 Orthobiologics: present state of commercial proposals. EGB 10:40-11:00 Recombinant Human Platelet-Derived Growth Factor-BB and guided tissue regeneration Victor Palarie vpalarie@gmail.com DISCUSSION: 11:05-11:15 BREAK 11:15-11:30 gabriela.ciapetti@ior.it 10:00-10:20 Endothelial cells influence osteogenic potential. Ying Xue Ying.xue@uib.no University of Bergen, Bergen, Norway DISCUSSION: 11:00-11:15 9:30-10:00 Chondrogenic potential of stem cells for cartilage reconstruction. Francisco J Blanco, Spain francisco.blanco.garcia@serga s.es 9:30-10:00 Bone marrow MSCs in clinical setting. M. Fernandez Universidad Autónoma de Madrid, Hospital Puerta de Hierro. Madrid, Spain manueln.fernandez@uam.es 10:00-10:30 Stem cells in osteoarthritis Gerben van Buul, g.vanbuul@erasmusmc.nl Holland 10:00-10:30 Platelet-lysate to expand MSCs for osteogenic human application. H. Schrezenmeier (Ulm) Germany h.schrezenmeier@blutspende. de 10:30-11:00 Sources of cells to reconstruct cartilage: the role of synovial and amniotic membrane. Francisco J Blanco,Hospital Universitario A Coruña, Spain francisco.blanco.garcia@serg as.es 11:00-11:15 Round table discussion on cartilage regeneration. Viernes 29 9:30-11:30 ROUND TABLE: Other sources of cells. Chair: Thimios Mitsiadis 9:30-10:00 MSCs from other origins: dissecting sources and isolation approaches for optimized bone and cartilage reconstructions.M. Dominici. University of Modena, Italy. massimo.dominici@unimore.it 10:00-10:30 Mesenchymal stem cells derived from human term deciduas. Ana Flores de la Cal. Hospital 12 de Octubre, Madrid, Spain. aflores.hdoc@salud.madrid.or 10:30-11:00 g. GMP protocols in the 10:30-11:00 expansion of mesenchymal Potential application of stem cells (MSCs) for human allogeneic stem cells in implantation. Rosa María bone regeneration. Rosaria Gonzalo, Hospital Puerta de Giordano. Cell Factory Hierro, Madrid, Spain Policlinico Milano, Italy. rosamaria.gonzalo@salud.madrid.org [rosaria.giordano@policlinico. mi.it]Italy 11:00-11:15 Round table discussion on 11:00-11:15 MSCs expansion for clinical Round table discussion on use. different sources of cells. 11:30-13:30 11:30-13:30 ROUND TABLE: Limits of tissue repair in Orthopaedics. Chair: José Antonio Rodriguez Montes. rodriguezmontes@gmail.co m 11:30-13:30 ROUND TABLE: Basic and applied strategies in bone regeneration. Chair: G. Ciapetti 12:00-12:30 Limits and opportunities for stem cell therapy in neural damage. Juan A. Barcia Hospital Clínico San Carlos, Madrid, Spain. [Juan.A.Barcia@uv.es], 11:30-13:30 ROUND TABLE: Neural damage and regeneration. Chair: JA Barcia. 11:30-13:30 ROUND TABLE: Clinical studies on bone. Chair: Enrique Gomez-Barrena 11:30-11:55 Cell tracking in regenerative medicine. Advantages and disadvantages of different 11:30-12:00 Bone defects, normal markers Reinhold Erben healing and impairment reinhold.erben@vu-wien.ac.at Austria EGB 11:30-12:00 Neural stem cell proliferation and differentiation in vitro and in vivo. Mª Salomé Siserol. Centro de Investigación Príncipe Felipe, Valencia, Spain. msirerol@ochoa.fib.es 11:55-12:20 Biomedical imaging of laboratory animals Sebastian Cerdan Instituto de Investigaciones Biomédicas, CSIC, Madrid, Spain scerdan@iib.uam.es Spain. 11:30-12:00 BM concentration in bone repair. Rationale and clinical application. Philippe Hernigou Hôpital Henri Mondor, CréteilParis, France. philippe.hernigou@wanadoo.f r France 12:00-12:30 Biomaterials for neural tissue regeneration. Ana Paula Pego. Portugal apego@ineb.up.pt Portugal jabarcia.hcsc@salud.madrid .org 12:20-12:45 Approaches to Bone Regeneration by Gene 12:30-13:00 Nuria Vilaboa. Cartilage defects and limits Therapy. of repair. Pedro Guillén . Hospital La Paz, Madrid, Spain. Clinica Cemtro, Madrid, nvilaboa@gmail.com Spain. consultapg@clinicacemtro. 12:45-13:10 Bone regeneration in the com setting of osteopenia. Therapeutic strategies. Pedro 13:00-13:30 Round table discussion on Esbrit. Fundación Jimenez Madrid, Spain tissue repair and Diaz, opportunities for pesbrit@fjd.es DISCUSSION 13:10-13:30 regenerative medicine. 12:00-12:30 Expanded MSCs in bone repair and regeneration. Philippe Rosset. CHU Tours, Tours, France. rosset@med.univtours.fr France 11:30-13:30 ROUND TABLE: Beyond bone and cartilage: lessons learned from other tissues and cells. Chair: Gustav Steinhoff. 11:30-12:00 MSCs therapies in other locations: the case of cardiac regeneration. Gustav Steinhof gustav.steinhoff@med.unirostock.de Germany 12:00-12:30 May MSCs become an injectable drug? Nan Ma nan.ma@med.uni-rostock.de 12:30-13:00 The tandem telocytes and 12:30-13:00 stem cells in regenerative Neural injury: spinal cord and 12:30-13:00 medicine. L Popescu. peripheral nerve regeneration. The risks of human MSCs lpopescu@jcmm.org Eva Sykova therapies. Luc Sensebé Etablissement Français de Sang, 13:00-13:15 sykova@biomed.cas.cz Toulouse, France. Czecj Republic Discussion luc.sensebe@efs.sante.fr France 13:00-13:30 Round table discussion on 13:15-13:30 13:00-13:30 neural damage and FINAL AND CLOSURE Round table discussion on regeneration. clinical studies on bone, benefits and risks. LUNCH 13:30-15:30 15:30-17:30 15:30-17:30 ROUND TABLE: Ethical and regulatory requirements. Chair: Isabel Varela-Nieto Instituto de Investigaciones Biomédicas, CSIC, Madrid, Spain ivarela@iib.uam.es 15:30-17:30 ROUND TABLE: Biomaterials. Chair: Kristine Arvidson. University of Bergen, Norway ( [Kristina.ArvidsonFyrberg@iko.uib.no]. Student presentations 15:30-16:00 discussion Scaffolds for bone tissue regeneration: overview and nanotechnology advances. M Vallet-Regi Universidad Complutense de Madrid, Spain. vallet@farm.ucm.es 15:30-16:00 Overview of ethical requirements: ESF Science Policy Briefing on human stem cell research. Maria Manuela Nogueira. EFS, Strasbourg, France. MNogueira@esf.org 16:00-16:30 Calcium phosphate cements 16:00-16:30 and foams for tissue European legal framework engineering and regenerative and public instruments to medicine. Maria Pau Ginebra support Stem Cell research. Universidad Politécnica de Javier Arias -Diaz. Instituto Cataluña, Barcelona, Spain. de Salud Carlos III, Madrid, Maria.Pau.Ginebra@upc.ed . Spain javardi@isciii.es Spain 16:30-17:00 Regulatory requirements of cell therapies. Cristina Avendaño-Solá. Hospital Puerta de Hierro, Madrid, Spain. cavendano.hpth@salud.ma drid.org 17:00-17:30 Round discussion pros and cons of investigator-driven 15:30-17:30 ROUND TABLE: Student presentations. Chair: Y. Konttinen. 16:30-17:00 MSCs in bone scaffolds: surface and survivorship P. Layrolle. France Inserm, Nantes, France. pierre.layrolle@inserm.fr 17:00-17:30 Round discussion on tissue engineering and biomaterials 15:30-17:30 ROUND TABLE: Morphogenesis, development and differentiation. Chair: Francisco J Blanco and 15:30-16:00 Tooth morphogenesis and cytodifferentiation. Thimios Mitsiadis , Zurich, Switzerland.. thimios.mitsiadis@zzm.uzh.ch Switzerland 16:00-16:30 Morphogenesis and limb development. Juan M. Hurle Universidad de Cantabria, Santander, Spain. hurlej@unican.es Spain 16:30-17:00 The creation of a biological joint: manufacturing a living osteochondral implant by developemental engineering. Frank Luyten Leuven University, Belgium. frank.luyten@uzleuven.be Belgium 17:00-17:30 Round discussion morphogenesis development on and clinical trials.