SCRIPT NUMBER 120 CIRRHOSIS OF THE LIVER - 2 (TWO SPEAKERS) PROGRAM NAME: HEALTH NUGGETS PROGRAM TITLE: CIRRHOSIS OF THE LIVER - 2 PROGRAM NUMBER: 120 SUBJECT: CAUSES, SYMPTOMS, TREATMENT, PREVENTION OF CIRRHOSIS KEY WORDS: HEPATITIS B, HEPATITIS C, CYTSIC FIBROSIS, TRANSPLANT, CONDOM DATE OF SCRIPT: July 12, 2013 AUTHOR: RICHARD YUKL, MD, FACS SPEAKER 1: Ludek is a 38-year-old man currently living in the Czech Republic. He found a bottle of vodka in a shoebox hidden in his mother’s closet when he was age 12. He sipped some and liked its taste. He made more and more frequent visits to his mother’s closet over several years, and then began buying alcoholic beverages with his own money, hiding his developing addiction from his parents. By age 18, Ludek was drinking three or more alcoholic beverages every day. SPEAKER 2: Ludek began noticing physical changes a few years ago that worried him. His skin became itchy. He gradually lost his appetite and began losing weight. Recently, the whites of his eyes began to turn yellow. He consulted a doctor, who identified that Ludek has developed cirrhosis of the liver. SPEAKER 1: Today, we want to talk about cirrhosis. What exactly is cirrhosis? SPEAKER 2: Cirrhosis is irreversible scarring of the liver most often caused by drinking excessive amounts of alcohol over many years. It is the third leading cause of death in adults between the ages of 45 and 65. The liver performs essential functions such as making chemicals that our body uses to destroy harmful substances entering our body. The liver also purifies our blood, and processes the nutrients from our diet that allow our bodies to function normally – things such as the proteins we eat. SPEAKER 1: What causes cirrhosis? SPEAKER 2: The specific cause of the scarring is chronic irritation. If the irritation is mild, the liver can repair itself and return to normal function, but as the irritation continues, more and more scar tissue forms, finally making it impossible for the liver to ever function normally again. SPEAKER 1: What causes the scarring? SPEAKER 2: Several conditions can irritate the liver severely enough to cause scarring. Infection by viruses such as Hepatitis B or Hepatitis C can cause the damage. Some genetic conditions such as cystic fibrosis can destroy the liver. Gallstones can obstruct the ducts that carry bile from the liver into the bowel, and destroy the liver. By far, however, the most common cause is the excessive drinking of alcohol. SPEAKER 1: Tell me the symptoms I will experience if I develop cirrhosis. SPEAKER 2: There may be no symptoms until liver damage is already severe. When symptoms do appear, you may experience extreme tiredness. Often, you will develop easy bruising and bleeding, and a loss of appetite with nausea and weight loss. Your body will have trouble fighting infections, so you may develop infections frequently. The most distressing symptom will be the accumulation of fluid in your legs and belly. Scar tissue makes it difficult for blood to flow freely through your liver, and the increased pressure that is required can cause the fluid portion of the blood to leak out of the vessels, collect in your legs and belly, and make your belly look pregnant. Untreated, the liver damage of cirrhosis will gradually worsen, finally causing health problems that are life threatening. As an example, the high blood vessel pressure that a scarred liver generates can cause blood vessels in the stomach and esophagus to burst, resulting in life threatening bleeding. SPEAKER 1: How is cirrhosis treated? SPEAKER 2: If you are suffering mild symptoms, as does Ludek, treatment is aimed at minimizing the liver damage that has already occurred. You must stop drinking alcohol immediately. That is not an easy task, and your doctor may recommend an effective treatment program located in your local area. The fluid that is collecting in your legs and belly, if not severe, can be managed with a low-salt diet and with water pills that help to eliminate fluids. Large amounts of fluid collected within your belly may require a doctor to drain it using a needle placed through your belly wall. A surgeon may also be able to place a tube into blood vessels being narrowed by a scarred liver, widening them to allow better blood flow through the narrowing. These extreme treatments are all helpful, but only if you can successfully stop drinking alcohol. SPEAKER 1: What if my symptoms are severe? SPEAKER 2: You want to avoid progression of cirrhosis to an advanced stage at all costs. Once cirrhosis is severe, your liver will not be able to recover. Because your liver is no longer able to clear poisons and harmful substances from your blood, you will begin having difficulty thinking clearly, become ever more confused, and finally develop a coma from which you cannot recover unless you undergo heroic therapy such as a liver transplant. SPEAKER 1: If I am presently healthy but at risk of developing cirrhosis, how can I prevent developing the disease? SPEAKER 2: Don’t drink alcohol. If you feel you must drink, drink no more than one alcoholic beverage a day. Also, limit the amount of fatty and fried foods you eat, as excess fat is stored in your liver, causing damage. Instead, eat a plant-based diet containing lots of raw fruits and vegetables. Fruits and vegetables contain the vitamins and minerals that your body needs. SPEAKER 1: Will anything else help? SPEAKER 2: Limit your risk of a virus infection of your liver. Your liver can become infected with viruses such as Hepatitis B or Hepatitis C when you share dirty needles to inject street drugs, and by having sex with someone who is infected. If you use street drugs, at least use a clean needle that you purchased yourself. If you cannot abstain from having casual sex, protect yourself by using a condom. These wise lifestyle choices will go a long way in protecting you against this deadly condition. SPEAKER 1: Health Nuggets is written by Dr. Richard Yukl, a medical doctor working in the United States. The medical views expressed in this program are his and may differ for your particular health needs. If you need medical advice, please consult a medical professional in your area.