Page 1 of 2
Oxford, Oxfordshire
Salary competitive
Permanent
Profile of Role
Oxford BioMedica’s Manufacturing Sciences & Technology (MSAT) team is being expanded to support an increasing portfolio of cell and gene therapies. The team ensures that the manufacturing processes are capable, compliant, in control and continuously improved as well as delivering technical support for deviations or manufacturing investigations, process troubleshooting, support of validation programmes, exploration of process design space and technology transfer.
A highly motivated and independent individual is sought to work within this team. The successful candidate will be expected to:

Have a strong background in process development, technology transfer and/or continual improvements of manufacturing processes operated within a GMP environment.

Have a strong interest in manufacture of biopharmaceuticals and/or experience of working with lentiviral vectors would be an advantage.

Plan and execute work activities related to scale-up, technology transfer and continual process improvement of bio manufacturing processes

Be responsible for trouble-shooting/technical support of all aspects of the manufacturing process for both in-house and CMO.

Maintain Oxford BioMedica’s process technologies at the fore-front of the industry.
Skills/Knowledge/Qualifications

Min. BSc/B.Eng/Postgraduate degree in Biology/Biochemistry, Chemical/Biochemical Engineering, or a related field.

At least 3 year’s relevant experience in a cGMP manufacturing environment.

A background in process development/technology transfer/bio manufacturing/ and engineering principles with lentiviral vectors would be an advantage.

Good level of communication and presentation skills.
Key Tasks

Technology development to optimise and improve current and future manufacturing capabilities; scale-up, technology transfer, support process validation and continual process improvements.

Be responsible for trouble-shooting/technical support of all aspects of the manufacturing process operated in-house and CMO.

Remain current with technology and regulatory guidelines.

Page 2 of 2
Competencies

A background in process development/technology transfer/bio manufacturing/ aseptic processing/vial filling would be desirable. A strong interest in manufacture of biopharmaceuticals and/or experience of working with lentiviral vectors would be an advantage.

Good practical competence and technical understanding of bio therapeutic manufacturing.

Any experience covering some aspect of mammalian cell culture, bioreactors, downstream processing or aseptic processing and vial filling would be an advantage

Demonstrated ability to work independently as well as in a team setting; working across interfaces with Research, Process R&D, Manufacturing and QA

Ability to execute complex projects to aggressive timelines with the ability to adapt to rapid changes in project priorities

Ability to work collaboratively in a matrix and complex project environment

Good written and verbal communication skills.

Be enthusiastic and motivated for working and solving very challenging projects

Effective communication skills to gain company support
The successful candidate will report to the Team Leader - MSAT.
Please use the cover letter to highlight how you meet the competencies for the role and to state your salary requirements and current salary. Your cover letter will be used along with your CV to assess your application
.
With your application could you please quote job reference OXB01.