Lesson: Transcription Unit 8: DNA, Protein Synthesis, and Genetic Technology Date: __________________ Biology I Objectives: SWBAT explain that DNA contains the instructions to make proteins, and that the DNA RNA protein pathway is called the central dogma of biology. SWBAT compare and contrast the properties of DNA and RNA SWBAT define the process of transcription Do Now 1. Place the following steps of DNA replication in ORDER: ____________________________ I. DNA unzips II. The sugar-phosphate backbone in the new strands is joined with covalent bonds III. Two new strands result, both of which are identical to the original strand. IV. Free nucleotides are added to the original strands by DNA polymerase 2. Imagine the original strand of DNA is white, and the new nucleotides are red. Which of the following represents two strands after DNA replication? What is the Central Dogma of Biology? ____________________________________________________________________________ ____________________________________________________________________________ ____________________________________________________________________________ ____________________________________________________________________________ ____________________________________________________________________________ ____________________________________________________________________________ ____________________________________________________________________________ ____________________________________________________________________________ ____________________________________________________________________________ ____________________________________________________________________________ ____________ ____________ ____________ ____________ What is RNA? ______________________________________ ______________________________________ ______________________________________ ______________________________________ ______________________________________ ______________________________________ ______________________________________ ______________________________________ ______________________________________ ______________________________________ ______________________________________ ______________________________________ ______________________________________ The Steps of Transcription 1) An enzyme ___________________ the DNA molecule by _____________ the hydrogen bonds. 2. An enzyme called ______________ ______________________ connects ______________________________ to their complementary bases. 3. When mRNA is done forming, it ____________________, and DNA ______________________________. >> Check for Understanding Using the top strand of DNA as the template, show what a complementary mRNA molecule would look like: 5’ CCGTATTTA 3’ 3’ GGCATAAAT 5’ ______________________________ Venn Diagram: Comparing RNA + DNA Use the following terms: Uracil, single-stranded, adenine, thymine, ribose sugar, double-stranded, translated into proteins, cytosine, nucleic acid, made up of nucleotides, introns removed RNA DNA Venn Diagram: Comparing Transcription and DNA replication Use the following terms: Results in two identical strands, RNA polymerase DNA unzipped, complementary bases paired, creates single-stranded molecule, DNA polymerase, original DNA comes back together Transcription DNA Replication Vocabulary Practice: Frayer Models Definition (in your own words) Example DNA Replication Definition (in your own words) Example Transcription Picture Non-example Picture Non-example