Name ____________________________________________________ Period __________ Date ____________________
Pedigree Lab
Procedure
Use the following website to answer the questions that follow.
http://learn.genetics.utah.edu/content/addiction/pi/
You need to use a computer where the speakers work. Some information given is in the
form of video clips and you need to take notes on them. The following case study is on the
addiction to nicotine and its inheritance in a family. You will create and be able to analyze a
pedigree at the end of this lab.
What is it?
1. What is a pedigree?
_________________________________________________________________________________________________
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2. What can you track in a pedigree?
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3. Why are large families best to use in a pedigree?
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4. What else can researchers also note to individuals based on their pedigree and
environmental factors?
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5. What is a risk factor?
_________________________________________________________________________________________________
_________________________________________________________________________________________________
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What do the symbols mean?
6. What do the following symbols mean in a pedigree?
= ________________________
= ________________________
= ________________________
= ________________________
= ________________________
= ________________________________________________
= ________________________________________________
= ____________________________________
= ____________________________________
Why do it?
7. Why is a pedigree a useful tool?
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8. What can researchers analyze from looking at a pedigree?
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9. What does it mean if a disease is diagnosed in many relatives that are blood related?
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10. What can scientists collect from family members to look for specific genes?
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11. Why do scientists typically examine multiple families?
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Case Studies:
Wally Marshall
12. How old is Wally? ____________
13. Does Wally use tobacco products? ____________
14. How do tobacco products make Wally feel? _______________________________________________
15. What types of medication is Wally taking? ________________________________________________
16. What is the correct symbol for Wally? ____________
Trudy Marshall
17. What was the cause of her death? ____________
18. How young was Trudy when she started to smoke? ____________
19. How did tobacco products make Trudy feel? _____________________________________________
20. What types of medication was Trudy taking? _____________________________________________
21. What is the correct symbol for Trudy? ____________
Ken Marshall
22. How old was Ken when he passed away? ____________
23. What was his cause of death? _______________________________________________________________
24. What contributed to his cause of death? ___________________________________________________
25. What is the correct symbol for Ken? ____________
Elizabeth Marshall
26. Is Elizabeth a smoker? ____________
27. When did Elizabeth first try smoking? ____________
28. How do tobacco products make Elizabeth feel? ___________________________________________
29. What types of medication is Elizabeth taking? ____________________________________________
30. What is the correct symbol for Elizabeth? ____________
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Allison Marshall
31. How old is Allison? ____________
32. Does Allison use tobacco products? ____________
33. What medical conditions does Allison have? _____________________________________________
34. What types of medication is Elizabeth taking? ____________________________________________
35. What is the correct symbol for Allison? ____________
Todd & Alex Marshall
36. At what age did they start smoking? ____________
37. How many packs of cigarettes do they smoke daily? ____________
38. How did they begin smoking? ____________
39. What types of medication are Todd and Alex taking? ____________________________________
40. What risk factors do the twins express? ___________________________________________________
41. How long after stopping their medication did they start smoking? ____________________
42. What are the correct symbols for Todd and Alex? __________________
Jennifer Marshall
43. Is Jennifer using tobacco products? ____________
44. When did Jennifer first try smoking? ____________
45. Was it difficult for Jennifer to stop smoking? ____________
46. How do tobacco products make Jennifer feel? ____________
47. What is the correct symbol for Jennifer? ____________
Joy Marshall
48. Does Joy use tobacco products? ____________
49. How many packs of cigarettes does Joy smoke daily? ____________
50. At what age did Joy start smoking? ________________________
51. What risk factors could be associated with her addition to cigarettes?
_________________________________________________________________________________________________
52. What types of medication is Joy taking? ________________________
53. What is the correct symbol for Joy? ____________
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Jason & Vanessa
54. Is Vanessa a smoker? ____________
55. When did Vanessa begin to smoke? ____________
56. How many cigarettes does Vanessa smoke daily? ____________
57. Is Jason a smoker? ____________
58. How many cigarettes does Jason smoke daily? ____________
59. Why were attempts for both Vanessa and Jason to quit smoking unsuccessful?
_________________________________________________________________________________________________
60. What are the correct symbols for Jason and Vanessa? ___________________
Michael & Tina
61. Is Michael currently using tobacco products? ____________
62. What activities does Michael do to stay healthy? ________________________________________
63. Is Tina currently using tobacco products? ____________
64. How often does Tina smoke? ____________
65. When did Tina begin smoking? ____________
66. What are the correct symbols for Michael and Tina? ________________________
Victor & Lily
67. Does Victor use tobacco products? ____________
68. When did Victor first try smoking? ____________
69. How do tobacco products make Victor feel? _____________________________________________
70. Does Lily use tobacco products? ____________
71. What health problems run in Lily’s family? ____________
72. What are the correct symbols for Victor and Lily? ________________________
Brian Marshall
73. Does Brian currently use tobacco products? ____________
74. How does Brian feel about tobacco products? ____________
75. What types of medication is Brian taking? ________________________________________________
76. What is the correct symbol for Brian? ____________
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Peter Marshall
77. Does Peter currently use tobacco products? ____________
78. How does Peter feel about tobacco products? ____________
79. What types of medication is Peter taking? ________________________________________________
80. What is the correct symbol for Peter? ____________
James Marshall
81. Does James currently use tobacco products? ____________
82. How many packs of cigarettes does James smoke daily? ____________
83. Why were James’ attempts at quitting unsuccessful?
_________________________________________________________________________________________________
84. When did James begin smoking? ____________
85. What types of medication is James taking? ________________________________________________
86. What risk factors could be associated with his addition to cigarettes?
_________________________________________________________________________________________________
87. What is the correct symbol for James? ____________
Linda Marshall
88. Does Linda currently use tobacco products? ____________
89. How does Linda feel about tobacco products? ____________
90. What types of medication is Linda taking? ________________________________________________
91. What is the correct symbol for Linda? ____________
Tess Marshall
92. Does Tess currently use tobacco products? ____________
93. How many packs of cigarettes does Tess smoke daily? ____________
94. How long ago did Tess begin to smoke? ____________
95. What risk factors could be associated with her addition to cigarettes?
________________________________________________________________________________________________
96. What is the correct symbol for Tess? ____________
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Conclusions
97. What are your clues that this pedigree shows a possible genetic component to
nicotine addiction? (circle all that apply)
a.
The trait is present in all generations
b.
Affected children have at least one affected parent
c.
Multiple children (from the same parents) are affected
98. What should your next steps be? (circle all that seem logical)
a.
Collect DNA samples from the people in this family who are addicted to
nicotine
b.
Collect DNA samples from the people in this family who are not addicted to
nicotine
c.
Identify and study other families with similar pedigrees
d.
Consider how risk factors seen in the Marshall family may influence nicotine
addition
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99. Fill out the pedigree with the correct symbols for each person as you go along with the lab. Use the symbols from the
first page. (question #6)
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