Biology 130
Dr. Matern
Sample Midterm 3
Part A: Fill-in. Write the appropriate answers in the space to the right.
The spindle consists of (1)____ radiating from the (2)____.
1. _________________
For every single cell that undergoes meiosis in human males there is a
maximum of (3)____ (how many) sperm cells produced?
For every single cell that undergoes meiosis in human females there is
a maximum of (4)____ (how many) ova produced?
2. _________________
3. _________________
4. _________________
Mendel's Law of (5)____ describes how the alleles for a single trait
5. _________________
separate when gametes are formed.
If two genes are 16 map units apart, a person who is heterozygous for
both traits will make about (6)____ % non-crossover gametes.
6. _________________
7. _________________
When homologous chromosomes or sister chromatids fail to separate
8. _________________
during meiosis, it is called (7)____.
9. _________________
The sugar in DNA nucleotides is (8)____.
In DNA replication, new nucleotides are added in the (9)____
10. ________________
direction.
In replication, the lagging strand is replicated in short segments that
11. ________________
12. ________________
are called (10)____.
Portions of the mRNA transcript that are cut out are called (11)____.
13. ________________
The molecules that carry amino acids to the ribosome are (12)____.
If the anticodon on a tRNA is "U C A," the corresponding codon
14. ________________
15. ________________
would be (13)____.
A regulated cluster of genes that code for polypeptides with related
functions is called a(n) (14)____.
Small, circular pieces of DNA that carry only a few genes and are
found in bacteria are called (15)____.
The enzyme (16)____ splices pieces of DNA together.
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16. ________________
Part B: In each of the following lists, three of the four items have something biological in
common. Circle the one that does not fit and make a positive statement which describes what is
common to the three but is not shared by the fourth.
1)
same centromere position
carry same alleles
separate in meiosis
same length
3)
ligase
primase
RNA polymerase
helicase
2)
nucleoli reappear
cell plate forms
chromosomes decondense
nuclear membrane reforms
4)
adenine
thymine
cytosine
guanine
Part C: Short answer
1) List all the phases of the cell cycle (3 interphase and 5 mitotic phases) in order, and specify
whether the chromosomes consist of a single chromosome or sister chromatids at each phase.
2) The following is the coding strand of a DNA molecule with letters standing for the four
different nucleotides.
T A C C A T G C G A T T T T T
a.) What is the complementary (non-coding) DNA strand?
b.) What is the corresponding mRNA strand?
3) List at least four types of RNA and give the role each plays in protein synthesis.
4) Flower position, stem length, and seed shape were three traits that Mendel chose to study.
Each is controlled by an independently assorting gene and has dominant and recessive
expression as follows:
Flower position:
dominant = axial (A)
recessive = terminal (a)
Stem length:
dominant = tall (T)
recessive = short (t)
Seed shape:
dominant = round (R)
recessive = wrinkled (r)
If a plant that is heterozygous for all three traits were allowed to self-fertilize, what proportion of
the offspring would be expected to be homozygous dominant for all three traits. Show work.
5) Big mouth is dominant to little mouth and polka-dot is dominant to plain coat. The genes are
linked, 16 map units apart. A female with a big mouth and polka-dot coat, whose mother was
heterozygous for mouth size and had a plain coat, and whose father had a little mouth and a
polka-dot coat, was married to a male homozygous for big mouth and plain coat. What will be
the genotypic and phenotypic ratios of their offspring? Show your work.
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