Name _____________ Hour_____ Biology 1 – 2 Test: DNA Structure and Replication Multiple Choice: Choose the best answer for the following questions. Write the letter in the blank. _____ 1. The building blocks that make up DNA are ______. a) amino acids b) nitrogen-containing bases c) nucleotides d) none of these _____ 2. The rungs of the DNA molecule are made up of ______________________. a) two-ringed and one-ringed bases c) a complementary base pair b) nitrogen bases d) all of these _____ 3. The sides, or backbone, of the DNA molecule consist of _____. a) nucleotides b) nitrogen-containing bases c) deoxyribose & phosphate of these d) all _____ 4. Which of the following is responsible for joining complimentary nitrogen bases? a) chemical bonds b) peptide bonds c) hydrogen bonds d) electromagnetic attractions _____ 5. If a DNA sample contains 22% adenine what percentage of cytosine will it contain? a) 22% b) 44% c) 56% d) 28% e) not enough information to determine _____ 6. Which of the following is NOT true about the structure of the DNA molecule? a) It is a triple helix. b) It exhibits complementary base pairing. c) The backbone is alternating sugars and phosphates. d) The sugar is deoxyribose. _____ 7. In the nucleic acid shown at right, the structure labeled x represents a(n) _______. a) covalent bond b) deoxyribose molecule c) replication fork d) phosphate group _____ 8. Which type of bond will form at the point labeled Y in the figure shown at right? a) peptide bond b) covalent bond c) hydrogen bond d) nitrogen bond _____ 9. The name of the molecule at right is _____. a) deoxyribose nucleic acid b) deoxyribonucleic acid Y x c) ribonucleic acid d) double nucleic acid 1 ____ 10. The complementary base-pairing rules state that the following are base pairs in DNA: a) adenine—thymine; uracil—cytosine. b) adenine—thymine; guanine—cytosine. c) adenine—guanine; thymine—cytosine. d) uracil—thymine; guanine—cytosine. _____ 11. If a mistake is made during the replication of a DNA molecule a(n) ______ will be used to correct it. a) bond b) DNA polymerase c) helicase d) lactase _____ 12. What is the function of helicase? a) unwinds the DNA helix in replication b) joins the nitrogen bases c) allows A to bond to G d) there is no such compound _____ 13. During replication, the two strands of DNA separate at a point called a ______. a) helicase b) ribosome c) replication fork d) mutation ____ 14. An error in DNA replication can cause a. mutations. b. cancer. c. d. genetic variation. All of the above _____ 15. The enzymes responsible for adding nucleotides to the exposed DNA template bases are a) replicases b) DNA polymerases c) Hydrogen bonds d) Covalent bonds _____ 16. Which of the following did Watson & Crick won the Nobel Prize for in 1953? a) The human DNA sequence. c) The importance of DNA. b) The structure of the DNA d) x-ray photo of DNA. molecule. . True or False? _____ 17. All cells contain DNA. _____ 18. The sugar-phosphate backbone of DNA is held together by strong covalent bonds. _____ 19. Rosalind Franklin is known for making models of DNA. _____ 20. The structure of DNA has been understood for centuries. 2 Fill In The Blank: 21. The name of the five carbon sugar in DNA is ___________________________________. 22. The shape of the DNA molecule is a ____________________________________________. 23. In ___________________________________________ (name of process) DNA is used to make more DNA. 24. Use the DNA code provided and fill in the complementary DNA strand. ATTCGATGC _____________________ TACGGATCG ______________________ Diagram: Complete the following diagram. Read the directions carefully. 25. Label the following diagram. What is this structure called? _______________________________________ 3 Short Answer: Complete all three of the short answer questions. Use complete sentences. 26. DNA replication is known as semi-conservative replication. What does this mean? 27. Using what you know about DNA, explain how the DNA of humans is similar to all other organisms (dog, banana, bacteria, etc.). 28. Describe how a molecule of DNA is replicated. Include the following words in your answer: enzymes, replication fork, nucleotide, complementary base pairs, template. UNDERLINE THE WORDS 4