Dr. Vajihe Akbari PhD of Pharmaceutical Biotechnology Corresponding address: Department of pharmaceutical biotechnology, Faculty of pharmacy and pharmaceutical sciences, Isfahan University of Medical Sciences, Isfahan, Iran Phone: 0098 3117922571 Email : v_akbari@pharm.mui.ac.ir Educational Background: Pharm .D Faculty of pharmacy, Kerman, Iran, 2002-2008 Titles of Pharm.D 's thesis: Preparation, characterization and cytotoxicity evaluation of ciprofloxacin loaded niosomes PhD Faculty of pharmacy, Isfahan, Iran, 2009-2014 Title of PhD 's thesis Construction, expression and biological activity evaluation of a single-chain Fv antibody fragment specific for domain II of HER2 receptor in Escherichia coli Experience: Scientific referee in 15th Iranian Seminar of Pharmacy Students (ISPS) (2010). Editorial assistants of Research in Pharmaceutical Sciences journal. A biannually publication of school of pharmacy and pharmaceutical sciences, Isfahan university of medical sciences, Isfahan, Iran. Editorial board of Drug Information Journal. A monthly publication of student research committee of school of pharmacy and pharmaceutical sciences, Kerman, Iran. Poster Presented at Conferences: Feizizadeh Sahar, Abbas Jafarian Dehkordi, Daryoush Abedi, and Vajihe Akbari. "Evaluation of antibacterial activity of Lactobacillus delbrueckii susp bulgaricuis against Escherichia coli" ECB15, 15th European Congress on Biotechnology, Istanbul, Turkey, 23-26 Sep. 2012. The abstract was indexed by New Biotechnology 29 (2012): S126-S127. Akbari Vajihe, Daryoush Abedi, Hamid Mir Mohammad Sadeghi, Abbas Jafrian-Dehkordi, and Perry Chou. "Cloning, expression and purification of a single chain variable fragment antibody against Her2 in Escherichia coli." ECB15, 15th European Congress on Biotechnology, Istanbul, Turkey, 23-26 Sep. 2012. The abstract was indexed by New Biotechnology 29 (2012): S117. V. Akbari, H. Sadeghi, D. Abedi, A. Pardakhty, S. Shafizadegan, Antimicrobial properties of non-ionic surafactant vesicles containing ciprofloxacin, The 12th Iranian Pharmaceutical sciences conference. The abstract was indexed by Research in Pharmaceutical Sciences, 2012; 2012;7(5) S15. A. Jafarian Dehkordi, D. Abedi, V. Akbari, S. Feizizadeh, Evaluation of anti-bacterial and anti-adherence properties of Lactobacillus delbrueckii susp bulgaricuis on Escherichia coli, The 12th Iranian Pharmaceutical sciences conference. The abstract was indexed by Research in Pharmaceutical Sciences, 2012; 2012;7(5) S411. Akbari.V, Sadeghi. H, Abedi. D, Pardakhty.A (2011). In-vitro antimicrobial activity of niosomal ciprofloxacin in comparison with free ciprofloxacin . The 1th Internarional and 12th Iranian congress of microbiology (international). Akbari.V, Pardakhty.A, Moshafi.M.H (2010). Preparation, characterization and cytotoxicity evaluation of ciprofloxacin loaded niosomes . The 12th Iranian Pharmaceutical sciences conference (international). Akbari.V, Pardakhty.A, Moshafi.M.H (2008). Intracellular delivery of niosomal ciprofloxacin in J774 cell line. The 11th Iranian Pharmaceutical sciences conference (international). Akbari.V, Pardakhty.A, Moshafi.M.H (2006). Formulation of non ionic surfactant vesicles (niosom) containing ciprofloxacin. The 12th Seminar of Iranian Pharmacy Students. Akbari.V, Mehrabani.M, Moshafi.M.H (2005). Evaluation of antibacterial effect of Maclura pomifera extract by cylinder plate method. The 11th Seminar of Iranian Pharmacy Students. Electronic poster Presented at Conferences: Akbari.V, Mofid MR. (2011). Binding mode of microtubule stabilizing agents to yeast tubulin. The 12th Iranian Congress of Biochemistry & 4th International Congress of Biochemistry and Molecular Biology. (international) The abstract was indexed by Clinical Biochemistry, Volume 44, Issue 13, Supplement, September 2011, Page S101 Oral Presented at Conferences: Akbari.V, Pardakhty.A, Moshafi.M.H (2007). Enhancement of encapsulation efficacy of ciprofloxacin in noiosomal vesicles by remote loading method. The 13th Seminar of Iranian Pharmacy Students Awards and Honors: Rewarded for been second in 16th generation of graduated students of Pharmacy of Kerman university of medical science. Rewarded for been third in pharmaceutics science of the 12th Seminar of Iranian Pharmacy Students. Rewarded for been fifth in 22th exam of pharmaceutical basic science of Iranian pharmacy students. Training workshop: Attended and successfully completed the theoretical and practical training workshop entitled How to present an academic paper on April 10, 2011. Attended and successfully completed the theoretical and practical training workshop entitled Systematic Review on January 23-24, 2011. Attended and successfully completed the theoretical and practical training workshop entitled Ultera Performance Liquid Chromatography (UPLC) on January 18, 2011. Attended and successfully completed the theoretical and practical training workshop entitled EndNote on September 4-5, 2010. Attended and successfully completed the theoretical and practical training workshop entitled SPSS on July 4-7, 2010. Attended and successfully completed training workshop entitled effective relationship on June 20-21, 2010. Attended and successfully completed the theoretical and practical training workshop entitled Real Time PCR on August 19, 2008. Attended and successfully completed the training workshop entitled Life Skills on January 23, 2006. Basic research skills: -Familiar with Windows, Microsoft office abilities. -Familiar with search methodology in the scientific data bases such as Medline. -Familiar with Endnote software in managing research reports/manuscript/papers. Professional skills: Experiences on molecular modeling and docking small molecules in proteins using softwares such as PyMol, Auto Dock. Experiences on molecule manipulation and analysis, sequence analysis, and synthetic gene design using softwares such VectorNTi, Gene Designer. Familiar with search (DNA/RNA , protein molecules, enzymes, single nucleotide polymorphism and BLAST search) in the data bases such as PDB, Expasy and Pubmed. Evaluation of cytotoxic activity of compounds against cancer/ normal cell lines (in vitro: cell culture assays). Some experiences on Intracellular infection models to evaluate efficacy of drug carriers for intracellular delivery of antimicrobial agents. (in-vitro). Research and Projects: No Title 1 Antimicrobial evaluation of ciprofloxacin loaded niosomes against intracellular Staphylococcus aureus infection in mouse J774 macrophages 2 Director/cooleague Second director Construction, expression and Second director biological activity evaluation of a single-chain Fv antibody fragment specific for domain II of HER2 receptor in Escherichia coli Date 2010 Grant University of Medical Sciences (Isfahan, Iran) 2011 University of Medical Sciences (Isfahan, Iran) Patent Single chain antibody specific for HER2 Iran patent patent number:80466 Publications: a ) Books 'The vaccines and their application in prevent and treatment of disease', in Persian. ‘Biological product Vaccines’ , in Persian ‘Blood biologiacal products’ , in persian b.) Articles published in ISI Journals: 1. Comparison of epothilone and taxol binding in yeast tubulin using molecular modeling. Vajihe Akbari, Sharareh Moghim and Mohammad Reza Mofid, Avicenna Journal of Medical Biotechnology. 2011;3(4):167-76. 2. Optimization of the Expression of Genes Encoding Poly (3-hydroxyalkanoate) Synthase from Pseudomonas aeruginosa PTCC 1310 in Escherichia coli. Daryoush Abedi, Maryam Beheshti, Ali Jahanian Najafabadi, Hamid Mir Mohammad Sadeghi, and Vajihe Akbari, Avicenna Journal of Medical Biotechnology. 2012;4(1):47-51. 3. Comparison of five methods for extraction of genomic DNA from a marine Archaea, Pyrococcus furiosus. Hamid Mirmohammadsadeghi, Daryoush Abedi, Hamid Reza Mohmoudpour and Vajihe Akbari, Pakistan Journal of Medical Sciences. 2013;29(1)Suppl:390-394. 4. Ciprofloxacin nano-niosomes for targeting intracellular infections: an in vitro evaluation. Vajihe Akbari, Daryoush Abedi, Abbas Pardakhty and Hojjat Sadeghi-Aliabadi, Journal of Nanoparticle Research. 2013; 15(4):1-14. 5. In vitro anti-bacterial and anti-adherence effects of Lactobacillus delbrueckii subsp bulgaricus on Escherichia coli. Daryoush Abedi, Sahar Feizizadeh, Vajihe Akbari and Abbas Jafarian-Dehkordi. Research in Pharmaceutical Sciences. 2013;8(4):261-8. 6. Akbari Vajihe, Mir Mohammad Sadeghi Hamid, Jafrian-Dehkordi Abbas, Abedi Daryoush, Chou CPerry. Functional expression of a single-chain antibody fragment against human epidermal growth factor receptor 2 (HER2) in Escherichia coli. J Ind Microbiol Biotechnol. 2014;41(6):947-56. 7. Feizizadeh Sahar, Salehi-Abargouei Amin, Akbari Vajihe. Efficacy and Safety of Saccharomyces boulardii for Acute Diarrhea. Pediatrics. 2014:peds. 2013-3950. 8. Akbari Vajihe, Mir Mohammad Sadeghi Hamid, Jafarian-Dehkordi Abbas, Chou C Perry, Abedi Daryoush. Optimization of a single-chain antibody fragment overexpression in Escherichia coli using response surface methodology. Research in Pharmaceutical Sciences. 2014;10(1):65-73.