Methods for a Single Categorical Variable – Confidence Intervals Up to this point in the semester we’ve been using sample data to judge whether the observed data is consistent with a statement about a population parameter or not. However, what happens when the researcher has no idea what the population parameter might be? In this instance, the researcher would use sample data to construct an interval, known as a confidence interval, which provides a range of ______________________________ values for the parameter of interest. Comments: A confidence interval allows the researcher to ____________________ the population parameter of interest. Several methods exist for constructing a confidence interval for a binomial proportion. However, we will focus on the _________________________ which is the type of interval JMP computes. Example: Osteoporosis is a disease defined as very low bone density resulting in high risk of fracture, hospitalization, and immobilization. Researchers are interested in estimating the true proportion of postmenopausal women who suffer from osteoporosis. A random sample of 50 postmenopausal women was taken, and eight of them said they suffer from osteoporosis. a. Define the population of interest. b. Define the sample. c. How big of a sample was taken for the study? This is your sample size, n. d. What proportion of the sample suffered from osteoporosis? This is your sample statistic, p̂ . 1 e. Next, we’ll need the appropriate quantile from the standard normal distribution. The standard normal distribution is symmetric and bell-shaped. The quantile values given below are determined by how big of a middle chunk of the distribution is desired due to the specified confidence level. Whenever quantiles from the standard normal distribution are needed, you’ll use one of the following values: Confidence Level 90% 95% 99% z quantile Suppose we are interested in constructing a 95% confidence interval for the true proportion of postmenopausal women who suffer from osteoporosis. What z quantile should we use? f. Now, we can use the information from parts c, d, and e to construct the confidence interval using the formula given below. 2npˆ + z z 2n + z 2 2 z 2 4npˆ 1 - pˆ 2 n + z2 Note: This gives us a range of values that is close to the “middle 95%” of the binomial distribution with n = 50 and p = 8/50 = 0.16. 2 g. Lastly, we must interpret what the interval means. Calculating the score confidence interval in JMP First, we’ll need to enter the data into JMP as follows. Next, choose Analyze Distribution from the menus at the top of the screen. Then put Osteoporosis in the Y, Columns box and Count into the Freq box as shown below. Click OK and you should get the following output. 3 Next, click on the little red arrow next to Osteoporosis and choose Confidence Interval 0.95. You should then get the following output. Margin of Error The margin of error is defined as the distance between the center of the confidence interval and either endpoint. For this problem we have: Upper Endpoint – Center of Interval = 0.28 – 0.18 So, the resulting margin of error = 0.10. Questions: 1. What happens to the margin of error when the confidence level decreases? For example, what will happen if we construct a 90% confidence interval instead of a 95% confidence interval? 2. What will happen to the margin of error and confidence interval if we increase the confidence level? Example: Luna et al. (Critical Care Medicine 2003) studied patients who were mechanically ventilated in the intensive care unit of six hospitals in Buenos Aires, Argentina. The researchers found that of the 472 randomly selected mechanically ventilated patients, 63 had clinical evidence of ventilator-associated pneumonia (VAP). Questions: 3. Using JMP, compute the 90% confidence interval for the true proportion of mechanically ventilated patients with VAP. 4. Interpret the confidence interval found in Question 3. 4 Example: According to a nationwide survey conducted in 200, 60% of parents with young children condone spanking their child as a regular form of punishment (Tampa Tribune, Oct. 5, 2000). A group of researchers in child development has noticed a rise in parents using alternative forms of punishments, such as timeouts, in lieu of spanking, and decided to test their claim. A random sample of 75 parents of young children was taken and asked whether they condone spanking as a form of regular punishment. Forty of the 75 parents said they condone spanking. Research Question – Is there evidence that fewer parents with young children are condoning spanking as a regular form of punishment? Questions: 5. Construct a 99% confidence interval by hand for the proportion of parents with young children who condone spanking as a regular form of punishment. 6. Interpret the confidence interval constructed in Question 5. 7. Using JMP, verify the 99% confidence interval computed in Question 5. 8. In 2000, 60% of parents with small children condoned spanking as a regular form of punishment. Using the confidence interval constructed in Question 5 does this provide evidence that fewer parents with young children are condoning spanking as a regular form of punishment? Explain. 5 Example: The Gerber Company sponsored a large survey of the eating habits of American infants and toddlers. Among the many questions parents were asked was whether their child had eaten fried potatoes on the day before the interview. Among the 679 infants 9 to 11 months old, 9% had eaten fried potatoes that day. Questions: 9. Using JMP, construct a 95% confidence interval for the true proportion of 9 to 11 month old infants who eat fried potatoes on a given day. 10. Interpret the confidence interval found in Question 9. 6