Home Projects Publications News Bio-Health Informatics Research Team Dr Huseyin Seker PUBLICATIONS 2015 Arinze Akutekwe, Huseyin Seker and S. Yang, “In Silico Discovery of Significant Pathways in Colorectal Cancer Metastasis Using a Two-Stage Optimization Approach”, (Accepted) IET Systems Biology, July 2015 Charalambos Chrysostomou, Huseyin Seker and Nizamettin Aydin, “CISAPS: Complex Informational Spectrum for the Analysis of Protein Sequences”, Advances in Bioinformatics, Volume 2015 (2015), Article ID 909765, January 2015 Arinze Akutekwe and Huseyin Seker, “Inferring the Dynamics of Gene Regulatory Networks via Optimized Recurrent Neural Network and Dynamic Bayesian Network”, IEEE CIBCB 2015 (12-15 August 2015, Niagara Falls, Canada) Charalambos Chrysostomou and Huseyin Seker, “Novel Protein Weight Matrix generated from Amino Acid Indices”, IEEE EMBC 2015 (25-29 August 2015, Milan, Italy) Arinze Akutekwe and Huseyin Seker, “Inference of Nonlinear Gene Regulatory Networks through Optimized Ensemble of Support Vector Regression and Dynamic Bayesian Networks”, IEEE EMBC 2015 (25-29 August 2015, Milan, Italy) Ferdi Sarac, Volkan Uslan, Huseyin Seker and Ahmed Bouridane, “Comparison of Unsupervised Feature Selection Methods for High-Dimensional Regression Problems in Prediction of Peptide Binding Affinity”, IEEE EMBC 2015 (25-29 August 2015, Milan, Italy) Naser Alfed, Fouad Khelifi, Ahmed Bouridane and Huseyin Seker, “Pigment network-based skin cancer detection”, IEEE EMBC 2015 (25-29 August 2015, Milan, Italy) Volkan Uslan and Huseyin Seker, “The quantitative prediction of HLA-B*2705 peptide binding affinities using Support Vector Regression to gain insights into its role for the Spondyloarthropathies”, IEEE EMBC 2015 (25-29 August 2015, Milan, Italy) Hanaa Hussain, Khaled Benkrid and Huseyin Seker, “Dynamic Partial Reconfiguration implementation of the SVM/KNN multi-classifier on FPGA for Bioinformatics application”, IEEE EMBC 2015 (25-29 August 2015, Milan, Italy) 2014 H. Hussain, K. Benkrid, and H. Seker, “Novel dynamic partial reconfiguration implementations of the support vector machines classifier on FPGA”, (Accepted) T. Journal of Electrical Engineering and Computer Science, September 2014. (DOI: 10.3906/elk-1402-18) A.B. Orun, E. Goodyer, H. Seker, G. Smith, V. Uslan and D. Chauhan, "Optimized parametric skin modelling for diagnosis of skin abnormalities by combining light back-scatter and laser speckle imaging", Skin Research and Technology journal, Vol.20(4), pp: 473-485, November 2014. (DOI:10.1111/srt.12142) C.O. Sakar, O. Kursun, H. Seker, F. Gurgen, N. Aydin, and O. Favorov, "Combining Multiple Views: Case Studies on Protein and Arrhythmia Features", Engineering Applications of Artificial Intelligence journal, Vol. 28, pp: 174-180, February 2014 (DOI:10.1016/j.engappai.2013.11.004) C.O. Sakar, O. Kursun, H. Seker and F. Gurgen, "Combining Multiple Clusterings for Protein Structure Prediction", International Journal of Data Mining and Bioinformatics, Vol.10(2), pp: 162-174, 2014 (DOI: 10.1504/IJDMB.2014.064012) Rainer Merkl, Ali Kilinc, Senck Selcuki and Huseyin Seker, Editors, Proceedings of the International Conference on Applied Informatics for Health and Life Sciences, October 2014 A. Akutekwe and H. Seker, “Particle swarm optimization-based bio-network discovery method for the diagnosis of colorectal cancer”, (Accepted) Proc. of the Workshop on Computational Intelligence for Biomedicine and Bioinformatics as part of the IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2-5 November 2014, Belfast, UK A. Akutekwe, S. Iliya and H. Seker, “An Optimized Hybrid Dynamic Bayesian Network Approach using Differential Evolution Algorithm for the Diagnosis of Hepatocellular Carcinoma”, (Accepted) Proc. of the 6th IEEE International Conference On Adaptive Science & Technology (IEEE ICAST 2014), 29-31 October 2014, Ota (Near Lagos), Nigeria. Serpil Ustebay, Ahmet Orun, Huseyin Seker and Ahmet Sertbas, “Investigating the amigdala-thread effects on cognitive learning via graphical domains and Bayesian networks”, (Accepted) Proceeding of the International Conference on Applied Informatics for Health and Life Sciences in conjunction with the Turkish-German Workshop on Bioinformatics: Recent Developments from Health to Nanotechnology, 19-22 October 2014, Kusadasi, Turkey Martin Mueller-Holtz, Huseyin Seker and Geoff Smith, "Measurement of Refractive Index using Terahertz Reflectance Mode on Fixed Quartz Sample Holder”, (Accepted) Proceeding of the International Conference on Applied Informatics for Health and Life Sciences in conjunction with the Turkish-German Workshop on Bioinformatics: Recent Developments from Health to Nanotechnology, 19-22 October 2014, Kusadasi, Turkey A. Akutekwe and H. Seker, “Two-Stage Bioinformatics Approach for the Diagnosis of Hepatocellular Carcinoma and Discovery of its Bio-Network”, (Accepted) Proceeding of the International Conference on Applied Informatics for Health and Life Sciences in conjunction with the Turkish-German Workshop on Bioinformatics: Recent Developments from Health to Nanotechnology, 19-22 October 2014, Kusadasi, Turkey M. Mueller-Holtz, H. Seker and G. Smith, "Wavelet de-noising and reconstruction of a micro-needle embedded in human skin ex-vivo using terahertz pulsed reflectance mode", (Accepted) Proc. of the IEEE EMBC 2014, 27-31 August 2014, Chicago, USA. H. Seker, V. Uslan, A.B. Orun, E. Goodyer and G. Smith, "Prediction of skin ages by means of multi-spectral light sources", (Accepted) Proc. of the IEEE EMBC 2014, 27-31 August 2014, Chicago, USA C. Chrysostomou and H. Seker, "Construction of protein dendrograms based on amino acid indices and discrete Fourier transform", (Accepted) Proc. of the IEEE EMBC 2014, 27-31 August 2014, Chicago, USA C. Chrysostomou and H. Seker, "Prediction of protein allergenicity based on signal-processing bioinformatics approach", Proc. of the IEEE EMBC 2014, 27-31 August 2014, Chicago, USA A. Akutekwe and H. Seker, "A hybrid dynamic Bayesian network approach for modelling temporal associations of gene expressions for hypertension diagnosis", (Accepted) Proc. of the IEEE EMBC 2014, 27-31 August 2014, Chicago, USA Y. Kocyigit and H. Seker, "Hybrid imbalanced data classifier models for computational discovery of antibiotic drug targets", (Accepted) Proc. of the IEEE EMBC 2014, 27-31 August 2014, Chicago, USA. V. Uslan, H. Seker and R.I. John, “A Support Vector-Based Interval Type-2 Fuzzy System”, (Accepted) FUZZ-IEEE 2014 (a part of IEEE WCCI 2014), Beijing, China, 6-11 July 2014. A. Akutekwe and H. Seker, “Two-Stage Computational Bio-Network Discovery Approach for Metabolites: Ovarian Cancer as a Case Study”, (Accepted) IEEEEMBS International Conferences on Biomedical and Health Informatics of the IEEE Engineering in Medicine and Biology Society, Valencia, Spain, 1-4 June 2014. A.B. Orun, H. Seker, E. Goodyer, G. Smith and V. Uslan, “An improvement of skin aging assessment by non-invasive laser speckle effect: A comparative texture analysis”, (Accepted) IEEE-EMBS International Conferences on Biomedical and Health Informatics of the IEEE Engineering in Medicine and Biology Society, Valencia, Spain, 1-4 June 2014. 2013 A. Celebiler, H. Seker, B. Yuksel, A. Orun, S. Bilgili and M.B. Karaca, "Discovery of connection between Age Related Macular Degeneration, MTHFR C677T and PAI 1 4G/5G gene polymorphisms and body mass index by means of Bayesian inference methods", T. Journal of Electrical Engineering and Computer Science, Vol.21, pp: 2062-2078, 2013. (DOI:10.3906/elk-1111-21) C.J. Carmona, C. Chrysostomou, H. Seker and M. J. del Jesus, "Fuzzy Rules for Describing Subgroups from Influenza A Virus Using a Multi-Objective Evolutionary Algorithm", Applied Soft Computing, Vol:13(8), pp: 3439-3448, August 2013. N. Norbert and H. Seker, "HIV Progression to AIDS: Bioinformatics Approach to Determining the Mechanism of Action", Current HIV Research journal, Vol. 11(1), pp: 30-42, 2013. (PMID:22998236) Huseyin Seker and Graham Ball, Editors, Proceedings of the International Conference on Applied Informatics for Health and Life Sciences, September 2013. V. Uslan and H. Seker, "Support vector-based fuzzy system for the prediction of mouse class I MHC peptide binding affinity", Proc. of the 13th IEEE International Conference on BioInformatics and BioEngineering (IEEE BIBE2013), Chania, Crete, Greece, 10-13 November 2013. V. Uslan and H. Seker, "Relational Fuzzy Clustering to Reveal Multifunctional Proteins in a Protein-Protein Interaction Network", Proc. of the International Conference on Applied Informatics for Health and Life Sciences, 9-11 September 2013, Istanbul, Turkey, pp: 25-28 H. M. Hussain, K. Bendrid and H. Seker, "Role of FPGAs as High Performance Computing Solution to Bioinformatics and Computational Biology Data", Proc. of the International Conference on Applied Informatics for Health and Life Sciences, 9-11 September 2013, Istanbul, Turkey, pp: 102-105 M. Quessou, I. Karacan and H. Seker "Mobile Device/Smart Phone Application for the Estimation of Warfarin Dosing", Proc. of the International Conference on Applied Informatics for Health and Life Sciences, 9-11 September 2013, Istanbul, Turkey, pp: 110-111. V. Uslan, and H. Seker, "Support Vector-Based Takagi-Sugeno Fuzzy System for the Prediction of Binding Affinity of Peptides", Proc. of the IEEE EMBC 2013, 3-7 July 2013, Osaka, Japan. (PMID: 24110624) C. Chrysostomou, and H. Seker, "Signal-processing based bioinformatics approach for the identification of influenza A virus subtypes in Neuraminidase genes", Proc. of the IEEE EMBC 2013, 3-7 July 2013, Osaka, Japan. (PMID: 24110375) C. Chrysostomou, and H. Seker, "Construction of Protein Distance Matrix Based on Amino Acid Indices and Discrete Fourier Transform", Proc. of the IEEE EMBC 2013, 3-7 July 2013, Osaka, Japan. (PMID: 24110625) H Hussain, K Benkrid, and H. Seker, "Reconfiguration-Based Implementation of SVM Classifier on FPGA for Classifying Microarray Data", Proc. of the IEEE EMBC 2013, 3-7 July 2013, Osaka, Japan. (PMID: 24110373) M.N. Kurnaz, and H. Seker, "A Framework Towards Computational Discovery of Disease Sub-types and Associated (Sub-) Biomarkers", Proc. of the IEEE EMBC 2013, 3-7 July 2013, Osaka, Japan. (PMID: 24110627) 2012 H. Hussain, K. Benkrid, A. Ebrahim, A.T. Erdogan, and H. Seker, "Novel Dynamic Partial Reconfiguration Implementation of K-means Clustering on FPGAs: Comparative Results with GPPs and GPUs", International Journal of Reconfigurable Computing, 2012 (Volume 2012 (2012), Article ID 135926) A. Orun and H. Seker, "Development of a computer game-based framework for cognitive behaviour identification by using Bayesian inference methods", Computers in Human Behavior Journal, Vol. 28(4), pp: 1332 - 1341, July 2012. M. Mueller-Holtz, H. Seker, J. McKenna, M. Prausnitz, M. E. Marlow and G. Smith, "Assessment of Microneedle Intradermal Penetration Depth Using Terahertz Pulsed Imaging", UK PharmSci 2012 Conference, 12-14 Sept 2012, Nottingham, UK. M.E. Marlow, H. Seker and G. Smith, "Characterisation of amorphous and crystalline domains using terahertz spectroscopy", UK PharmSci 2012 Conference, 12-14 Sept 2012, Nottingham, UK. H. Hussain, K. Benkrid, C.Hong, and H. Seker, "An adaptive FPGA implementation of multi-core K-nearest neighbour ensemble classifier using dynamic partial reconfiguration", Proceedings - 22nd International Conference on Field Programmable Logic and Applications, (FPL2012), Article number:6339251, pp:627-630, August 2012, Oslo, Norway H. M. Hussain, K.Benkrid and H. Seker, "An Adaptive Implementation of a Dynamically Reconfigurable K-Nearest Neighbour Classifier on FPGA", NASA/ESA Conference on Adaptive Hardware and Systems (AHS-2012), June 25-28, 2012, Germany. Z.C. Gormez, O. Kursun, A. Sertbas and H. Seker, "Statistical Bias and Variance of Gene Selection and Cross Validation Methods: A Case Study on Hypertension Prediction", Proc. of IEEE BHI2012, China, 5-7 January 2012. L. Picinali, C. Chrysostomou and H. Seker, "The Sound of Proteins", Proc. of IEEE BHI2012, China, 5-7 January 2012. A.B. Orun, F. Kurugollu and H. Seker, "Behaviour analysis of micro-organisms to observe invisible substance effects: towards more sensitive biological effect detectors", Proc. of IEEE BHI2012, China, 5-7 January 2012. Y. Kocyigit and H. Seker, "Imbalanced Data Classifier By Using Ensemble Fuzzy C- Means Clustering", Proc. Of IEEE BHI2012, China, 5-7 January 2012. 2011 N. Nwankwo and H. Seker, "Digital Signal Processing Techniques: Calculating Biological Functionalities", Journal of Proteomics and Bioinformatics, Vol. 4(12), pp: 260-268, 2011 N. Nwankwo and H. Seker, "Preliminary Investigations into the Binding Interactions between Plasmodial and Host Proteins using Computational Approaches", Journal of Proteomics and Bioinformatics, Vol. 4(12), pp: 269-277, 2011 H.M. Hussain, K. Benkrid, A.T. Erdogan and H. Seker, "Highly Parameterized K-means Clustering on FPGAs: Comparative Results with GPPs and GPUs", Proc. of the 2011 International Conference on ReConFigurable Computing and FPGAs, November 30 - December 2, 2011, Cancun, Mexico C. Chrysostomou, H. Seker, N. Aydin, "Investigation into the effects of an individual amino acid on protein function by means of a Resonant Recognition Model", Lecture Notes in Computer Science, Vol. 6935, September 2011 L.A. Wall, M. Mueller-Holtz, I. Ermolina, M.J. Gamlen, H. Seker, G. Smith, "Evaluating lactose content within Avicel® PH-101 tablets by computational analysis of terahertz waveforms", UKPHARM, September 2011 C. Chrysostomou, H. Seker, N. Aydin, "Effects of windowing and zero-padding on Complex Resonant Recognition Model for protein sequence analysis", Proc. of EMBC 2011, Boston, USA, 30 August -3 September 2011 (PMID: 22255450) H.M. Hussain, K. Benkrid, H. Seker, A.T. Erdogan, "FPGA Implementation of K-means Algorithm for Bioinformatics Application: An Accelerated Approach to Cluster Microarray Data", Proc. of 2011 NASA/ESA Conference on Adaptive Hardware and Systems (AHS-2011), pp: 248-255, June 6 – 9, 2011, San Diego, California, USA H. Seker, (abstract for invited talk), "Recent advances and challenges in the computational discovery of biomarkers for genomics, proteomics and metabolomics", International Journal of Experimental and Clinical Pathophysiology and Drug Research, pp: 500-501, Vol. 25 (3), May-June 2011 (supplement for the 4th Int. Conf. of Molecular Medicine, June 2011, Istanbul, Turkey) H. Seker, "Computational Discovery of Personalised Biomarkers", Proc. of the International Congress on Bioinformatics and Biomics (18-22 May 2011), Kusadasi, Turkey. 2010 C. Chrysostomou, H. Seker, N. Aydin and P. I. Haris, "Complex Resonant Recognition Model in Analysing Influenza A Virus Subtype Protein Sequences", Proc. of IEEE ITAB 2010, Corfu, November 2010, pp:1-4. M. Gorania, H. Seker and P.I. Haris, "Predicting a protein's melting temperature from its amino acid sequence", Proc. of IEEE EMBC, Sept. 2010, pp:18201823. (PMID: 21095941) N. I. Nwankwo and H. Seker, "A signal processing-based bioinformatics approach to assessing drug resistance: Human Immunodeficiency Virus as a case study", Proc. of IEEE EMBC, Sept. 2010, pp: 1836-1839 (PMID: 21096145) I. Ali and H. Seker, "A comparative study for characterisation and prediction of tissue-specific DNA methylation of CpG islands in chromosomes 6, 20 and 22", Proc. of IEEE EMBC, Sept. 2010, pp: 1832-1835. (PMID: 21096144) H. Kaya, O. Kursun and H. Seker, "Stacking Class Probabilities Obtained from View-Based Cluster Ensemble", Lecture Notes in Computer Science, June 2010, vol. 6113/2010, pp: 397-404. N. Nwankwo and H. Seker, "Assessment of the binding characteristics of human Immunodeficiency virus Type 1 Glycoprotein120 and Host Cluster of Differentiation4 Using Digital Signal Processing", Proc. of The 10th IEEE International Conference on Bioinformatics and Bioengineering (BIBE-2010), May 31-June 3, Philadelphia, USA, 2010. H. Seker, "Analysis of Protein Sequences by using Signal Processing Methods", (invited paper), Proc. of Workshop on Recent Advances in Applications of Bioinformatics and Biomics, July 12-14 2010, Çeşme, Turkey, pp: 35-47. H. Seker, "Data Mining in Metabolomics", (invited paper), Metabolomics Summer School, 4 - 10 July 2010, Trabzon, Turkiye, pp: 271-291. Pre-2010 publications I. Ali and H. Seker, “Detailed methylation prediction of CpG islands on human chromosome 21”, Proc. of the 10th WSEAS International Conference on Mathematics & Computers in Biology & Chemistry, 2009. C. Newby, Y. Yang and H. Seker, “Investigation into Effectiveness of Rough Sets in Prediction of Enzyme and Protein Structure Classes”, Proc. of IEEE IJCNN, 2009 C.O. Sakar, O. Kursun, H. Seker, F. Gurgen, N. Aydin, O.V. Favorov, “Parallel Interacting Multiview Learning: An Application to Prediction of Protein SubNuclear Location”, Proc. of the 9th International Conference on Information Technology and Applications in Biomedicine (IEEE ITAB 2009), 2009 S. S. Nanuwa, A. Dziurla and H. Seker, “Weighted Amino Acid Composition based on Amino Acid Indices for Prediction of Protein Structural Classes”, Proc. of IEEE ITAB, 2009 H. Seker, “Novel weighted-amino acid composition for prediction of protein structural classes within the context of multi-sensor fusion approach”, Proc. of the 8th IEEE International Conference in Bioinformatics and Bioengineering, 2008 S. S. Nanuwa and H. Seker, “Investigation into the role of sequence-driven-features for prediction of protein structural classes”, Proc. of the 8th IEEE International Conference in Bioinformatics and Bioengineering, 2008 H. Seker, “Novel weighted-amino acid composition for prediction of protein structural classes within the context of multi-sensor fusion approach”, Proc. of the 8th IEEE Int. Conf. in Bioinformatics and Bioengineering, Athens, October 2008. H.Seker et al., “A bioinformatics approach to identification of metalloproteins”, Proc. of the ISMB/ECCB 2007, Vienna, July 2007. H. Seker, “Multiple Clustering Models and SVD-QR-based Method for Reliable Gene Expression Profile Analysis”, Proc. of the IPMU 2006, pp: 2821-26, Paris, July 2006. H. Seker, R. Abdulla, and P. Harris, “Developing a non-alignment based approach for identifying predictive features in metal binding proteins”, Proc. of 2004 Congress Proteomics for Health, December 2004, Bern, Switzerland. H. Seker, R. Abdulla, and P. Harris, “Prediction of metal binding proteins based on secondary structure information using a fuzzy logic-based method”, Proc. of 2004 Congress Proteomics for Health, December 2004, Bern, Switzerland. H. Seker, “A Multi-Fuzzy Filtering Approach to Reliable Gene Expression Profile Analysis”, Proc. of the 2004 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, October 2004, San Diego, CA, USA, pp: 37-40. M. Frize, D. Ibrahim, H. Seker, et al. “Predicting Clinical Outcomes for Newborns using Two Artificial Intelligence Approaches”, Proc. of the 26 th Annual IEEE EMBS 2004 Conference, San Francisco, CA, USA, Sept. 2004, pp:3202-3205. (PMID: 17270961) H. Seker et al., “Analysis of cellular and molecular markers by statistical, artificial neural networks and fuzzy logic-based approaches as an aid in intelligent prognostic decision making in oncology”, Recent Research Developments in Cellular Biochemistry, Chapter 4, Transworld Research Network, pp: 79-97, 2004. H. Seker, M.O. Odetayo, D. Petrovic and R.N. Naguib, “A fuzzy logic based method for prognostic decision making in breast and prostate cancers”, IEEE Transactions on Information Technology in Biomedicine, Vol. 7(2), pp: 114-122, June 2003. (PMID: 12834167) H. Seker, M.O. Odetayo, D. Petrovic, R.N.G. Naguib, and F. Hamdy, “An Intelligent Hybrid Neuro-Fuzzy Rule-Based System for Prognostic Decision Making in Prostate Cancer Patients”, Proc. of the 4th Annual IEEE Engineering in Medicine and Biology Society Special Topic Conference on Information Technology Applications in Biomedicine, April 2003, Birmingham, UK. H. Seker, M. Odetayo, D. Petrovic, R.N.G. Naguib, C. Bartoli, L. Alasio, M.S. Lakshmi and G.V. Sherbet, “A Neuro-Fuzzy Rule-Based Intelligent Survival Analysis of Breast Cancer Patients using Histological and Image Cytometric Prognostic Factors”, Proc. of the 94 th Annual Meeting of American Association for Cancer Research, April 2003, Toronto, Canada. H. Seker, M. Odetayo, D. Petrovic, R.N.G. Naguib, C. Bartoli, L. Alasio, M.S. Lakshmi and G.V. Sherbet, “Assessment of Nodal Involvement in Breast Cancer Patients Using Histological and Image Cytometric Prognostic Factors”, Proc. of the 93rd Annual Meeting of American Association for Cancer Research, San Francisco, CA, USA, April 2002 (Abstract). C.J. James, H. Arochena, A. Boardman and H. Seker, Editors, Proceedings of the IEEE EMBSS UK & RoI Postgraduate Conference in Biomedical Engineering and Medical Physics, Birmingham, UK, 2002 (ISBN: 0-9543157-0-7) H. Seker, M. Odetayo, D. Petrovic, R.N.G. Naguib, C. Bartoli, L. Alasio, M.S. Lakshmi and G.V. Sherbet, “A Hybrid System for Nodal Involvement Assessment in Breast Cancer Patients”, Proc. of the 2nd Joint Meeting of IEEE EMBS-BMES, October 2002, Houston, TX, USA. H. Seker, M.O. Odetayo, D. Petrovic, and R. Naguib, “Prognostic Decision Making in Prostate and Breast Cancers: Comparison of Statistical, Neural Networks and Fuzzy Approaches”, Proc. of The 6th World Multiconference on Systemics, Cybernetics and Informatics (SCI 2002), Orlando, USA, July 2002. H. Seker, M. Odetayo, D. Petrovic, R.N.G. Naguib, C. Bartoli, L. Alasio, M.S. Lakshmi and G.V. Sherbet, “An Artificial Neural Network Based Feature Evaluation Index for the Assessment of Clinical Factors in Breast Cancer Survival Analysis”, Proc. of IEEE Canadian Conference on Electrical and Computer Engineering, Manitoba, Canada, May 2002. H. Seker, M. Odetayo, D. Petrovic, R.N.G. Naguib, C. Bartoli, L. Alasio, M.S. Lakshmi and G.V. Sherbet, “Soft Feature Evaluation Indices for the Identification of Significant Image Cytometric Factors in Assessment of Nodal Involvement in Breast Cancer Patients”, Proc. of IEEE 2002 International Conference on Fuzzy Systems, Honolulu, USA, May 2002, vol.2, pp: 1592 – 1595. H. Seker, M.O. Odetayo, D. Petrovic, R.N.G. Naguib, and F. Hamdy, “A hybrid system for prognosis in prostate cancer”, Proc. of the IEEE EMBSS UK & RoI Postgraduate Conference in Biomedical Engineering and Medical Physics, Birmingham, July 2002, pp: 18. H. Seker, M.O. Odetayo, D. Petrovic, R.N. Naguib, C. Bartoli, L. Alasio, M.S. Lakshmi and G.V. Sherbet, “Assessment of nodal involvement and survival analysis in breast cancer patients using image cytometric data: statistical, neural network and fuzzy approaches”, Anticancer Research (International Journal of Cancer Research and Treatment), Vol.22(1), pp: 433-438, Jan-Feb. 2002. (PMID: 12017328) H. Seker et al., “Prognostic Comparison of Statistical, Neural and Fuzzy Methods of Analysis of Breast Cancer Image Cytometric Data”, (Award Winning Paper from IEEE Engineering in Medicine and Biology Society) The 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, October 2001. H. Seker, D.H. Evans, N. Aydin, E. Yazgan, and R.N.G. Naguib, “Intelligent Detection of Abnormal Neonatal Cerebral Heamodynamics in A Neonatal Intensive Care Environment”, Proc. of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, October 2001, Istanbul, Turkey. H. Seker, M.O. Odetayo, D. Petrovic, R. Naguib, and F. Hamdy, “Statistical and Soft Feature Evaluation Indices for Prostate Cancer Prognostic Factor Assessments”, Proc. of EUSFLAT 2001-An International Conference in Fuzzy Logic and Technology, 2001, Leicester, UK, pp: 26-29. H. Seker, D.H. Evans, N. Aydin and E. Yazgan, “Compensatory fuzzy neural networks based intelligent detection of abnormal neonatal cerebral Doppler ultrasound waveforms”, IEEE Transactions on Information Technology in Biomedicine, Vol. 5(3), pp: 187-194, September 2001. (PMID: 11550840) H. Seker, M. Odetayo, D. Petrovic, R.N.G Naguib, C. Bartoli, L. Alasio, M.S. Lakshmi, G.V. Sherbet, "A fuzzy measurement-based assessment of breast cancer prognostic markers", 2000, Proceedings of the IEEE/EMBS Region 8 International Conference on Information Technology Applications in Biomedicine, ITAB, pp. 174-178 H. Seker and D.H. Evans, "Non-normalized compensatory hybrid fuzzy neural networks", 1999, Proceedings of the International Joint Conference on Neural Networks, pp. 4300-4303 L. Ozyilmaz, T. Yildirim and H. Seker, "EMG signal classification using conic section function neural networks", 1999, Proceedings of the International Joint Conference on Neural Networks, pp. 3601-3603 H. Seker and M. Korurek, "Fuzzy Relation Matrix and fuzzy Max-Min operation for biomedical signal classification", 1998, Proceedings of the International Conference on Biomedical Engineering Days, pp. 57-59 H. Seker, N. Aydin and E. Yazgan, "Wavelet-based signal reconstruction for quadrature signals in Doppler ultrasound", 1998, Proceedings of the International Conference on Biomedical Engineering Days, pp. 60-61.