Mentor CV - Society for Pediatric Radiology

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BIOGRAPHICAL SKETCH
NAME
Rajesh Krishnamurthy
POSITION TITLE
Director for Research, Department of Radiology, Texas Children’s Hospital
Associate Professor of Radiology and Pediatrics, Baylor College of Medicine
EDUCATION/TRAINING
INSTITUTION AND LOCATION
Stanley Medical College, Madras University
Yale University School of Medicine
DEGREE
MB,BS
Fellowship
YEAR(s)
1993
1997
FIELD OF STUDY
Medicine
University of Texas-Houston Medical School
Residency
2001
Diagnostic Radiology
Children’s Hospital, Boston, Harvard Med School
Children’s Hospital, Boston, Harvard Med School
Fellowship
Fellowship
2002
2003
Pediatric Radiology
Pediatric Cardiac MRI
Nuclear Medicine
A. Personal Statement
I am the director for research at the EB Singleton Department of Pediatric Radiology at Texas Children's Hospital, and am
primarily responsible for the development and oversight of our departmental intramural and extramural research portfolio.
I am also director of the cardiovascular imaging program, and lecture nationally and internationally on pediatric
cardiovascular and body MRI, and cardiovascular CT. My interests include adaptation of MR sequences for free-breathing
acquisition in sedated children, low dose volumetric CT for cardiovascular applications, assessment of end-organ injury to
the cardiovascular system from systemic diseases in children amongst others.
B. Committees and Honors.
Committees: (Representative)
 Chairman, Pediatric Radiology Scientific Program Sub-Committee, RSNA, 2013-2015
 Pediatric Program Co-Chair, Society of Cardiac MRI, 2014-2016
 Invited Speaker, American Institute of Radiologic Pathology, 2005-2015
 Immediate Past Chair, Cardiac imaging task force, Society of Pediatric Radiology 2011-2013
 Member, NIH/NHLBI working group on "Thrombosis in Pediatric Cardiology and Congenital Heart Disease", 2012
 Pediatric Cardiac Imaging task force and accreditation committee, American College of Radiology,
 ACR-NASCI Collaborative Committee to Develop Practice Guidelines for the Performance and Interpretation of
Cardiac Magnetic Resonance Imaging (MRI)
 American Society of Echocardiography Writing Committee to develop ‘Multi-modality Imaging
Guidelines for Patients with Repaired Tetralogy of Fallot’.
 Rating Panel for the Appropriate Utilization of Cardiovascular Imaging in Heart Failure, American
College of Radiology and American College of Cardiology, 2011
Honors:
 Certificate of Acheivement, Academy of Radiology Leadership and Management, Jan 2015
 John Kirkpatrick Young Investigator Award for Best Clinical Science Research, Society of Pediatric Radiology,
2012
 Research Mentor Award from Texas Children’s Hospital for the year 2010-2011
 John Caffey Award for Best Clinical Science Research, Society of Pediatric Radiology, 2004
 Neuhauser Traveling Fellowship at Boston Children’s Hospital to the European Society of Pediatric Radiology,
2003
 Cum Laude award at the 87th meeting of the Radiological Society of North America at Chicago, 2001
 The 1998 Roentgen Resident/Fellow Research Award, Radiological Society of North America
C. Recent selected peer-reviewed publications (in chronological order). (Not comprehensive:Total 62
publications)
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Jadhav SP, Golriz F, Atweh LA, Zhang W, Krishnamurthy R. CT Angiography of Neonates and Infants:
Comparison of Radiation Dose and Image Quality of Target Mode Prospectively ECG-Gated 320-MDCT and
Ungated Helical 64-MDCT. Am J Roentgenol. 2015; 204(2):W184-91.
Krishnamurthy R, Pednekar A, Atweh LA, Vogelius E, Chu ZD, Zhang W, Maskatia S, Masand P, Morris SA,
Krishnamurthy R, Muthupillai R. Clinical validation of free breathing respiratory triggered retrospectively cardiac
gated cine balanced steady-state free precession cardiovascular magnetic resonance in sedated children.
Journal of Cardiovascular Magnetic Resonance 2015, 17:1
PHS 398/2590 (Rev. 09/04, Reissued 4/2006)
Page
Biographical Sketch Format Page
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Krishnamurthy R, Hernandez A, Kavuk S, Annam A, Pimpalwar S. Dynamic MR Lymphangiography (d-MRL): A
New Technique to Assess the Central Conducting Lymphatics. Radiology 2014 Oct 15:131399. Epub 2014 Oct
15.
Brian W McCrindle, Jennifer S Li, Cedric Manlhiot, James S Tweddell, Therese M Giglia, M Patricia Massicotte,
Paul Monagle, Rajesh Krishnamurthy, et al. Challenges and Priorities for Research: A Report From the National
Heart, Lung, and Blood Institute (NHLBI)/National Institutes of Health (NIH) Working Group on Thrombosis in
Pediatric Cardiology and Congenital Heart Disease. Circulation Sep;130(14):1192-203
Mery CM, Lawrence SM, Krishnamurthy R, Sexson-Tejtel K, Carberry KE, McKenzie DE, Fraser CD. Anomalous
aortic origin of a coronary artery: Towards a standardized approach. Seminars in Thoracic and Cardiovascular
Surgery 2014;26(2):110-22.
Mery CM, Molina KM, Krishnamurthy R, Fraser CD Jr, Justino H. Pulmonary artery resuscitation for isolated
ductal origin of a pulmonary artery. J Thorac Cardiovasc Surg. 2013 Dec 31. [Epub ahead of print]
Valente AM, Cook S, Festa P, Ko HH, Krishnamurthy R, Taylor AM, Warnes CA, Kreutzer J, Geva T.
Multimodality imaging guidelines for patients with repaired tetralogy of fallot: a report from the american society of
echocardiography: developed in collaboration with the society for cardiovascular magnetic resonance and the
society for pediatric radiology. J Am Soc Echocardiogr. 2014;27(2):111-41.
Maskatia SA, Spinner JA, Nutting AC, Slesnick TC, Krishnamurthy R, Morris SA. Impact of Obesity on Ventricular
Size and Function in Children, Adolescents and Adults With Tetralogy of Fallot After Initial Repair. Am J Cardiol.
2013;112(4):594-8.
Krishnamurthy R, Yoo JH, Thapa M, Callahan MJ. Water-bath method for sonographic evaluation of superficial
structures of the extremities in children. Pediatr Radiol. 2013;43 Suppl 1:41-7.
D. Research Support (Representative)
CFLD-NET
Leung (PI)
01/01/2008 – 12/31/2015
Prediction by Ultrasound of the Risk of Hepatic Cirrhosis in Cystic Fibrosis (PUSH). Cystic Fibrosis Liver Disease
Network (CFLD-NET). To determine the utility of abdominal ultrasound at enrollment to predict the development
of cirrhosis in subjects with cystic fibrosis within a five year period. Role: Co-Investigator
Thrasher grant
Bacha (PI)
08/01/2011- 03/31/2015
Determinants of Subclinical Coronary Atheroscelrosis and Endothelial Dysfunction in Youth with and without
Type 2 Diabetes. The purpose of this investigation is to study the ontogeny of endothelial
dysfunction and
coronary atherosclerosis in youth and to discern the effect of insulin resistance vs hyperglycemia in the
pathogenesis of subclinical coronary atherosclerosis and abnormalities in endothelial function. Role: CoInvestigator
Koninklijke Philips Electronics
Krishnamurthy (PI)
11/01/2014 – 10/31/2015
Free-breathing strategies for pediatric cardiovascular and body MRI, evaluation of diffuse liver disease, and
time-resolved MRA.
Cardiovascular Research Institute Morris and Krishnamurthy (co-PI)
08/01/2013- 07/31/2014
Investigating the Association between Vascular Tortuosity and Adverse Cardiovascular Events in Children and
Young Adults with Aortic Dilation Using a Novel Imaging Biomarker. The specific aims are to determine if higher
vertebral tortuosity index (VTI) is associated with earlier first cardiac surgery, aortic dissection, and death in
children and young adults, and to determine if VTI significantly changes over time.
5R21 HL110330-02
Krishnamurthy (PI)
05/31/2011- 05/31/2013
Dependence of Cardiomyocyte Electrophysiology Development on ContractileStrain . Using MRI sequences and
echocardiography data from hearts with single right
ventricle (SRV), single left ventricle (SLV) and dual
ventricle with a single ventricle strategy repair (DV), in pediatric patients to evaluate cardiac fiber strain and
compare to hearts with normal geometry.
1R56DK090350-01A1 Krishnamurthy (PI)
09/24/2012-08/31/2013
Development of MR Based Biomarker Panels for NAFLD a NASH CRN Ancillary Study. To develop pediatricand adult-specific MR biomarker panels to diagnose NASH in subjects with NAFLD.
1R56DK090350-01
Krishnamurthy (PI)
09/30/2010-06/30/2012
Development of MR Based Biomarker Panels for NAFLD a NASH CRN Ancillary Study To develop pediatric- and
adult-specific MR biomarker panels to diagnose NASH in subjects with NAFLD.
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