Clinical Vignettes Patient Info You are a medical student on placement at a general practice. Your next patient is Mr Jones a 75 year old gentleman who has come to discuss his shortness of breath. Please take a history from this patient. Role play info Patient 1 Name: Mr Ricky Jones Age: 75 PMH Asthma when a child Hypertensive Hyperlipidemia Operations PC Short of breath None Social History HPC Progressively worse SOB over the last month Dry cough has become worse over last 6 months Small wheeze noticed in the mornings No sputum brought up o Reveal haemoptysis ONLY if directly asked Feels a tightening of chest wall as well Exercise tolerance reduced from 100m walking to 15m walking in 1 year Has had problems sleeping, and feels tired all the time Has not noticed weight loss (but if prompted he has dropped a belt size) Smoked 15 a day for 50 years Does not drink Lives with wife who has carers 2x a day DHx Anti-hypertensives Statins Paracetamol for the chest pain Allergies – hay fever Concerns Finding it increasingly difficult to look after his wife with his SOB. Does not want to let her down. DDx Investigations Lung cancer FBC TB Sputum Gram stain, culture & Lung abscess COPD CXR Vasculitis (Wegner’s) CT-chest ILD Bronchoscopy CHF Cytology Patient 2 volunteer this info unless Name: Mr Benjamin Walker Age: 76 directly asked) Has a cough that won’t go away, especially at night PC No haemoptysis Swelling of his ankles First noticed it 3 weeks ago No leg pain when walking to the local Feeling very tired and weak shop to get a newspaper Otherwise well It has been getting Normally leads an active life progressively worse Eats a take away 2-3 times a Now unable to walk until the end of drive way because of SOB Cannot sleep flat has week Does not enjoy fruit and veg PMH increased number of pillows Hypertensive up to 3 from 1 (Do not Hyperlipideamia volunteer this info unless MI 8 years ago directly asked) over last 2 weeks Short of breath HPC Producing pink frothy sputum Has woken up gasping with air in the middle of the night a number of times (Do not Social History Lives alone in a 2 – story house (cannot get up the stairs without being short of breath), has to pause for breath. Booked a holiday to Australia Normally capable and able to in 3 months’ time to see look after himself brother. Worried he won’t be Ex-pilot now retired able to make the trip. Smokes 12 a day for the last 60 years Alcohol socially 1-2 pints a week DHx Antihypertensives, and statins NKDA (no known drug allergies) No allergies FHx DDx Heart failure (LVF) CCF Cardiac Valvular disease Pulmonary fibrosis COPD Investigations FBC CXR Father died of an MI ages 62 ECG Mother died of old age Echo Brother who is well BNP No children Concerns Mini cases Give you a flavor for common PC’s and the common DDx and Dx. 30 yo M presents with shortness of breath, cough, and wheezing that worsen in cold air. He has had several such episodes in the past 4 months. Differential Asthma GORD Bronchitis Pneumonitis Foreign body 56 yo F presents with shortness of breath and productive cough that lasts for at least 3 months each year in the past 2 years. She is a heavy smoker. Differential COPD—chronic bronchitis Bronchiectasis Lung cancer Tuberculosis 58 yo M presents with 1 week of pleuritic chest pain, fever, chills, and cough with purulent yellow sputum. He is a heavy smoker with COPD. Differential Pneumonia COPD exacerbation (bronchitis) Lung abscess Lung cancer Tuberculosis Pericarditis 25 yo F presents with 2 weeks of nonproductive cough. Three weeks ago she had a sore throat and runny nose. Differential Atypical pneumonia Reactive airway disease URI-associated cough (“postinfectious”) Postnasal drip GORD 65 yo M presents with worsening cough for the past 6 months accompanied by hemoptysis, dyspnea, weakness, and weight loss. He is a heavy smoker. Differential Lung cancer Tuberculosis Lung abscess COPD Vasculitis (ie, Wegener) Interstitial lung disease CHF 55 yo M presents with increased dyspnea and sputum production for the past 3 days. He has COPD and stopped using his inhalers last week. He stopped smoking 2 days ago. Differential COPD exacerbation (bronchitis) Lung cancer Pneumonia URI CHF 34 yo F nurse presents with worsening cough of 6 weeks’ duration accompanied by weight loss, fatigue, night sweats, and fever. She has a history of contact with tuberculosis patients at work. Differential Tuberculosis Pneumonia Lung abscess Vasculitis Lymphoma Metastatic cancer HIV/AIDS Sarcoidosis 35 yo M presents with shortness of breath and cough. He has had unprotected sex with multiple sexual partners and was recently exposed to a patient with active tuberculosis. Differential Tuberculosis Pneumonia (including Pneumocystis jiroveci) Bronchitis CHF (cardiomyopathy) Asthma Acute HIV infection 50 yo M presents with a cough that is exacerbated by lying down at night and improved by propping up on 3 pillows. He also reports exertional dyspnea. Differential CHF Cardiac valvular disease GORD Pulmonary fibrosis COPD Postnasal drip