Ther 202: Pharmacotherapeutics Medications and Integrative Lec 12:Herbal Herbal Medications and Integrative Medicine Medicine Ma. Stephanie Fay S. Cagayan, MD Mind-Body Interventions TOPIC OUTLINE I. Definitions A. Health and Wellness B. Oriental/Traditional and Western Medicine C. Complementary and Alternative Medicine II. Why Should We Care About CAM? III. Issues on the Use of CAM/Herbal Medicine IV. What Can We Provide to Meet the Demand? Biological Based Therapies Manipulative and BodyBased Methods Energy Therapies I. DEFINITIONS A. HEALTH AND WELLNESS Health (WHO): A state of complete physical, mental and social well-being and not merely the absence of disease or infirmity Ther 202 1 August 28, 2014 cognitive-behavioral approaches, meditation, hypnosis, dance, music, art therapy, prayer, mental healing Dietary supplements, herbs, orthomolecular (varying concentrations of chemicals, such as, magnesium, melatonin, and mega-doses of vitamins), individual biological therapies (use of laetrile, shark cartilage, bee pollen). Chiropractic, osteopathic manipulation, massage Qi gong, Reiki, therapeutic touch, bioelectromagnetic-based therapies (pulsed fields, magnetic fields, or alternating current or direct current fields) II. WHY SHOULD WE CARE? 60% of Filipinos still lack access to doctors Majority of Filipinos are below poverty level and cannot afford cost of health care 600 million visits a year to CAM providers – more than to primary care providers Why? What is mainstream medicine not offering to our patients? A. HAVE WE MISSED THE BOAT? Figure 1. Components of Wellness B. ORIENTAL/TRADITIONAL MEDICINE AND WESTERN MEDICINE Oriental/Traditional Western Dissatisfaction with health care providers and medical outcomes Side effects of drugs and treatments High health costs/No choice Technology Lack of control in their own health care practices Time spent with practitioner Looking for “cures” Want to use “natural” products Patient feels empowered Focus on spirituality and emotional well-being Health Care Provider provides the 3 T’s: touch, talk, time No choice B. WHAT ABOUT COMMUNICATION? Figure 2. Comparison between Oriental/Traditional Medicine and Western Medicine B. COMPLEMENTARY AND ALTERNATIVE MEDICINE • • Complementary and Alternative Medicine is a group of diverse medical and health care systems, practices, and products that are not presently considered part of conventional medicine (NCCAM) o Complementary medicine: used together with conventional medicine o Alternative medicine: used in place of conventional medicine Integrative medicine combines mainstream medical therapies and CAM therapies for which there is some high-quality scientific evidence of safety and effectiveness C. HISTORICAL DEVELOPMENTS: GLOBAL Table 1. Modalities under the 5 Domains of CAM (WILL BE ASKED!) Ayurveda, Chinese, Native American, Aboriginal, African, Middle Eastern, Tibetan, Central and South American cultures, Homeopathy, Naturopathy Jeff Geoff Marz World Health Organization (WHO): 1978 Alma Ata Declaration on Primary Health Care (PHC): Integration of Traditional Medicine in PHC 1999: US Congress established the National Center for Complementary and Alternative Medicine (NCCAM) in the National Institutes of Health (NIH) Bethesda, Maryland. Worldwide Perspective o Complementary o Alternative o Traditional o Primary medical care o Treatment of minor ailments o Health maintenance D. GOALS OF USE/TREATMENT WITH CAM Figure 3. 5 Domains of CAM Alternative Medical Systems Between 40 and 70% of CAM users do not disclose their use to their physician o 60% - “My doctor never asked.” o 60% - “It wasn’t important for my doctor to know.” o 20% - “My doctor wouldn’t understand.” o 14% - “My doctor would disapprove.” 70% of patients see their Physician before or concurrent with their visits to a CAM provider Why would we not trust CAM? o Quackery o Doctors concerned because several cases reported of liver failure with Kava Kava, a widely used natural remedy for anxiety 1. 2. 3. 4. 5. Promotion and maintenance of health Prevention of disease and injury Relief of pain and suffering Cure of curable diseases and illnesses Care of people who are ill Page 1 / 4 Herbal Medications and Integrative Medicine 6. 7. Avoidance of premature death Peaceful death E. REGULATIONS Varied from stringent to none Canada o Federal and provincial regulations o 2004 National Health Products Regulations European Union o Directive to register and license products Mexico o Traditional birth attendants, homeopathic chiropractors licensed o Registry of traditional practitioners China and India o Integrated with allopathic medicine, regulated Ther 202 o About 40% of medicinal plants used in indigenous communities have not been documented There are about 250,000 traditional medical practitioners in the Philippines See appendix for list of medicinal plants III. ISSUES ON THE USE OF CAM/HERBAL MEDICINE A. SAFETY OF HERBAL MEDICINE practitioners, F. PHILIPPINE EXPERIENCE IN INTEGRATIVE MEDICINE Mid-70’s: Private physicians started training in acupuncture in China Early 1980’s: DOH physicians trained acupuncture in China; herbal medicine production started 1993-95: DOH established the Traditional Medicine Unit which promoted the use of medicinal plants, acupuncture and therapeutic massage 1995: De La Salle University inaugurated the Center for Indigenous Medicine in Dasmarinas, Cavite -the 1st Philippine university to do so. 1997: Republic Act 8423 (TAMA) established the Philippine Institute for Traditional and Complementary Health Care (PITAHC) in as an attached agency of the Department of Health (DOH). Traditional and Alternative Medicine as defined by RA 8423 o The scope of alternative health care modalities as other forms of non-allopathic, occasionally non-indigenous or imported healing methods, though not necessarily practiced for centuries nor handed down from one generation to another. 1999-2000: Filipino physicians have organized the Philippine Association of Medical Acupuncturists Inc (PAMAI) and the Philippine College for the Advancement of Medicine (PCAM) to promote the practice of Integrative Medicine. 2001: The UP College of Medicine started an elective course on Integrative Medicine in both graduate and undergraduate courses. The UP-Philippine General Hospital inaugurated the Traditional and Integrative Medicine Clinic. 2008 -The Philippine Institute of Traditional and Alternative Medicine (PITAHC) started the accreditation of acupuncturists practicing in the Philippines, both for medical and non-medical practitioners. Figure 4. Reported Actions, Treatments, Adverse Reactions and Drug Interactions of Herbal Alternative Medicines used in Neuropsychiatry (transers’ note: Ma’am said she might ask about this, esp. on St. John’s Wort! Bigger copy found in appendix) B. EVIDENCE BASED MEDICINE Difficulties With CAM Research o Sham Acupuncture o Non Standardized Herbal Formulations o Difficult to Blind Patients and Practitioners o Treatments Very Individualized – Difficult to Formulate Protocols Mainstream Medicine o Large Double Blind Placebo Controlled Trials o Many Exclusions Such As Multiple Medicines, Other Illnesses, Female, Pregnant, Children, Race o “Placebo Effect” Discounted o Apply These Narrow Results to The Individual Integrative Medicine o Very Individualized o “Placebo Effect” Not Discounted G. WORLD VIEW OF HEALTH IN FILIPINO TRADITIONAL MEDICINE C. CHALLENGES TO THE FILIPINO COMMUNITY Theory of macrocosm and microcosm (“kalawakan” “sangkatauhan”) The balance, synergy and harmony: o Between Humankind and the Universe o Between Humankind and Nature o Between and Amongst people o Within his body, mind and spirit Theory of nature elements o fire (kalikasan ng apoy) o earth (kalikasan ng lupa) o water (kalikasan ng tubig) o air (kalikasan ng hangin) Theory of body humours o Init (hot) and lamig (cold) o Wet (basa) at Dry (tuyo) Belief in nature spirits/guardians of nature and spirit ancestors at 1. 2. 3. H. FOLK OR TRADITIONAL MEDICINE 80% of Third World countries utilize folkloric medicine Formal training vs apprenticeships vs observation, imitation, practice o Skill may be inherited Range of remedies o prayer, touch, charms, rituals, teas, tinctures, poultice, etc All cultures I. HERBAL MEDICINE IN THE PHILIPPINES 4. 5. 6. 7. 8. Majority of Philippine medicinal plants remain undocumented and untapped. Scientific studies supporting Philippine traditional medicine practices is still in the early phase and full potential has not been explored Lack of collaboration among research institutions, private sector and academe NIRPROMP (National Integrated Research Program on Medicinal Plants o A multidisciplinary research team established in 1976 under the Department of Science and Technology o Tasked to validate scientifically certain folkloric uses of medicinal plants and to propagate the use of herbal medicines rationally by the majority of the people (for example, sambong has a folkloric use for cough but upon scientific validation, it is now used as a diuretic) Lack of investments in research and development, raw material production, post harvest processing and herbal manufacturing. Low level of scientific technology in herbal medicine research and manufacture among small and medium enterprises. Low support for traditional medicine research in the academic community. Need for market and government incentives like the ones given to rice, corn, coconut, sugar, bananas, pineapples and mangoes. Need for standardized procedures/ accreditation/recognition in Filipino traditional medicine/herbal medicine practices. 8,000 to 12,000 flowering plants 1,500 species actively utilized by traditional healers Jeff Geoff Marz Page 2 / 4 Herbal Medications and Integrative Medicine Ther 202 D. ANSWERS TO CHALLENGES A wareness raising N etworking among groups T echnical capacity building I nformation exchange/monitoring D eepening of understanding O rganizing concerned people T ransformative action E mpowerment of people Awareness, understanding and appreciation of resources Capability for a relevant and self-reliant research and development program Recognition and respect of community rights and indigenous knowledge Strong national policies and laws to protect indigenous resources Active defense against immediate threats to biodiversity (mining, deforestation) Preventive action against potentially destructive technologies/activities (developmental aggression) Confronting structural causes of unsustainable use (political system) IV. WHAT CAN WE PROVIDE TO MEET THE DEMAND? Patients are choosing integrative and alternative medicine, but what about us, physicians? A. THE FUTURE OF INTEGRATIVE MEDICINE The Future Is Sometimes Curing, But Always Caring Integrative medicine requires a paradigm shift from: o The disease-centered approach of conventional medicine to o To an approach in which patient values and participation of patients are central Definition of Integrative Medicine from the CAHCIM o Integrative medicine is the practice of medicine that reaffirms the importance of the relationship between practitioner and patient, focuses on the whole person, is informed by evidence, and makes use of all appropriate therapeutic approaches to achieve optimal health and healing. The term “Integrative Medicine will die o Our patients will demand integrative medicine from all of us o Training will be demanded by medical students o Training will be demanded by residents Integrative medicine will be a skill set added on just like: o Electronic health records o New medications o New procedure How do we add on these skills? o Build your database o Build a referral team o Ask your patients whom they see o Look for summaries of available data o Have an open dialogue with your patients What cannot be added on is empathy, open-mindedness and respect for other people’s beliefs SUMMARY Know what integrative medicine is Dialogue with your patients Build your database Build your referral base Develop patient care teams Consider all available options Be open-minded Be an agent of change in your community Above all: be caring, concerned and compassionate END OF TRANSCRIPTION Jeff: Geoff: Marz: Hello, block 5-star (physician)! Kain tayo please. Or roadtrip haha. Hello sa dating(?) transmates ko, Micah and Kit! Hi MSSR 2017, closing party na bukas for AMSEP PH for Taiwan, punta kayo please haha :D #domore #bemore Hello swim team babawi ako sa October! Jeff Geoff Marz Page 3 / 4 Herbal Medications and Integrative Medicine Medicinal Plant Lagundi (Vitex negundo) Sambong (Blumea balsamifera) Akapulko (Cassia alata) Yerba Buena (Mentha arvensis) Tsaang Gubat (Carmona retusa) Pansit-pansitan (Peperomia pellucida) Ampalaya (Momordica charantia) Niog-niogan (Quisqualis indica) Ipil-Ipil (Leucaena leucocephala) Bawang (Allium sativum) Sibuyas (Allium cepa) Bayabas (Psidium guajava) Roselle (Hibiscus sabdariffa) Sili (Capsicum frutescens) Luya (Zingiber officinale) Turmeric (Curcuma longa) Malunggay (Moringa oleiferanale) Balanoy (Ocimum basilicum) Sinta (Andrographis paniculata) Banaba (Lagerstroemia speciosa) Jeff Geoff Marz Ther 202 Uses Bronchodilator, Anti-cough, Anti-inflammatory, Analgesic, Anti-gout, Antioxidant, Antihistamine, Anti-spasmodic, Hypoglycemic Anti-urolithiasis, Diuretic, Anti-hypertensive, Anti-hyperuricemia, Anti-oxidant, Antibacterial, Anti-cough Antifungal, Antibacterial, Anti-scabies, Laxative, Antioxidant, Anticancer, Anthelmintic (in dogs) Analgesic, Anti-inflammatory, Antioxidant, Vasorelaxant, Antimicrobial, Antiviral, Anti-mite (avian) , Choleretic, Antispasmodic, Anti-flatulence, Anti-ulcer, Antifertility (male) Anti-spasmodic, Anti-diarrheal, Antimicrobial, Anti-dental caries, Analgesic Anti-hyperuricemia, Anti-inflammatory, Analgesic, Antibacterial, Wound healing, Diuretic Antidiabetic, hypolipidemic, Antioxidant, Antiviral, anti-HIV, Antimutagenic, Antifertility, Antiprotozoa, Anti-tumour (skin papilloma) Antihelminthic (fruits) , Antirheumatism (roots), To relieve boils and ulcers (leaves) Antihelminthic, Antiviral (yellow fever, dengue), Antibacterial, Cell proliferation inhibitor (potential anticancer) Antibacterial, antifungal, Anti-cholesterol, hypolipidemic, Anti-hypertensive, Anti-platelet, anti-coagulant, fibrinolytic, Anti-inflammatory, Hypoglycemic , Anti-spasmodic Anti-cholesterol, hypolipidemic, Anti-platelet, anti-coagulant, Hypoglycemic, anti-diabetic, Anti-bacterial, antifungal, Anti-inflammatory, anti-keloid , Anti-allergy, Anti-spasmodic Antibacterial, Anti-scorbutic, antioxidant, Anti-diarrheal, Anti-diabetic, Anti-mutagenic Antioxidant, Antihypertensive, diuretic, Antidiabetic, hypolipidemic, Anti-inflammatory, Antiplatelet, Cardioprotective, neuroprotective, Liver protective, Anticancer Analgesic, anti-arthritis, Antioxidant, Cardioprotective, Antihypertensive, Antimicrobial, Antidiabetic, Hypolipidemic Anti-inflammatory, anti-arthritis, Carminative, antispasmodic, Antimicrobial, antiviral, Anti-motion sickness, antiemetic, Anti-angiogenesis, anticancer, Antidiabetic, antilipidemic Anti-dyspepsia, anti-ulcer, choleretic, Anti-inflammatory, anti-arthritis, Anti-oxidant, anticancer, anti-angiogenesis, Prevents liver and kidney damage, Antidiabetic, anti-obesity, Vasorelaxant, Promotes wound healing Antioxidant, Antibacterial, antifungal, Anti-inflammatory, Antidiabetic , Anti-hypertensive, hypolipidemic, Hepatoprotective, Antitumour, Water purifier Antioxidant, cardioprotective, Antimicrobial, preservative, Antiplatelet, hypolipidemic, Antidiabetic, antihypertensive, Antimutagenic, Anticancer, Anti-ulcer, anti-stress, Anti-inflammatory, immunomodulator, Insecticidal, larvicidal Treatment of upper respiratory infections, Antibacterial, antiviral (HIV), Immunomodulatory, Anti-inflammatory, antipyretic, Antidiarrheal, Antimalaria, Hepatoprotective, Antivenom (cobra) Antidiabetic, Diuretic, To relieve dysuria, Antihypertensive, Anti-obesity Page 4 / 4