BIOL 3200 Genetics (CRN: #30135/30136) 4cr Spring 2015 Instructor: Dr. Carrie S. Thurber Email: cthurber@abac.edu **This is the best way to get in touch with me** Daytime Phone: (229) 391-5115 Office: Conger 214 Office Hours: M 9:00-10:00a T 10:00-11:00a; 11:00a-12:00p; 1:00p-4:00p W 9:00-10:00a R 2:00-4:00p F 9:00-10:00a **Additional hours by appointment only; BOLD hour is at the AAC** Course Meetings: MWF 11:00-11:50 am, Conger 227 AND either M 2:00-4:50 pm, Britt 102 OR W 2:00-4:50 pm, Britt 102 Course Description: This course introduces students to a survey of modern genetics including: classical Mendelian, population, and molecular genetics. Selected topics include protein synthesis, gene regulation, chromosomal inheritance and variation, linkage and mapping, DNA replication, evolutionary genetics, and genetic engineering. There are three hours of lecture and three hours of lab each week. Prerequisites: MATH 1112 OR MATH 1113, BIOL 1108/1108L, and CHEM 2040/2040L all with a grade of “C” or higher. Course Objectives: By the end of this course students should be able to: Describe the stages of Mitosis/Meiosis/DNA Replication/Transcription/Translation and explain their importance in the cell Draw Punnet Squares/Branch Diagrams and calculate allele, genotype and phenotype frequencies Interpret Pedigree data and draw conclusions based on that data Explain how modes of inheritance, gene linkage, mutation and evolutionary forces affect genes in a population Describe how sex determination and sex-linked genes can control phenotypes Compare and contrast genetics in prokaryotes versus eukaryotes Describe DNA and RNA technologies, identify when to use specific technologies, and interpret data resulting from experiments Note: Students may vary in their competency levels on these outcomes. Students can expect to achieve these outcomes only if they honor all course policies, attend class regularly, complete all assigned work in good faith and on time, and meet all other course expectations of them as students. Page 1 of 7 Course Materials: 1. Essentials of Genetics, 8th Edition, Klug et al. Pearson Publishing *Additional readings may be posted on the web and/or distributed in class 2. Sapling Online Homework Code **This will be provided FREE of charge for Spring 2015** 3. 882-E scantrons (6 total; YOU are responsible for bringing these to each exam!) 4. I-clicker 2 Textbook Website: http://www.masteringgenetics.com/ Sapling Online Homework Website: http://saplinglearning.com Class website: https://abac.view.usg.edu/ (Desire2Learn) **I will post slides, grades and messages/important news so check REGULARLY** : Grading: Grades will be based on class participation, in-class work, homework, quizzes and exams. iclicker2 Participation Sapling Online Homeworks 30 pts (1 pt/class for answering questions) 50 pts (5 x 10 pts each, due before exam date for covered material) D2L Online Quizzes 25 pts (6 x 5 pts each, lowest/missed quiz dropped) Hourly In-Class Exams 500 pts (5 x 100 pts each) Comprehensive Final Exam 100 pts Group Oral Presentation 50 pts Lab Grade 235 pts (See additional Lab Syllabus) Total 990 pts Lecture grades will be determined on the percentages listed below of all the possible points that you EARN. Percentages will be rounded UP to the nearest whole number when assigning letter grades. In the event that a student’s final class percentage is close to the next highest grade category, the instructor may consider lecture attendance, lecture preparation and participation, and/or submission of extra credit assignments in determining the final class grade. Grading Scale: A= > 90% ( > 890 pts) B= > 80% (790- 889 pts) C= >70% ( 690- 789 pts) D= >60% ( 590- 689 pts) F= <60% ( < 589 pts) Page 2 of 7 Specific Assignment Details: 1. iClicker Participation: You are required to purchase an iclicker2 remote for in-class participation. iclicker2 is a response system that allows you to respond to questions the instructor poses during class, and you will be graded on your in-class participation using the iclicker2. In order to receive this credit, you will need to purchase and register your iclicker2 remote by 01/12/15. You must come to class at least once and vote on at least one question in order to complete this registration properly. Once you have responded to a question with your iclicker2, go to http://www.iclicker.com/registration. Complete the fields with your first name, last name, student ID, and remote ID. Your student ID should be your ABAC 918 number. The remote ID is the series of numbers and sometimes letters found on the bottom of the back of your iclicker2 remote. iclicker2 will be used every day in class, and you are responsible for bringing your remote and extra batteries daily. If you forget your clicker you will not earn points for that class and may be marked absent! Anyone who attends class with more than one iclicker2 ( i.e. a friends or other classmates) will have all iclickers confiscated for the class period and all parties involved will lose HALF of the TOTAL semester points for participation; a second offense will result in loss of ALL participation points. 2. Sapling Online Homework: Sapling is a website that contains study materials and online assignments to help students learn and study the material. I will be assigning five (5) homeworks (10 pts each) consisting of multiple chapters of material that will be due by 10:30AM on the day of the exam covering such material. There may be an additional BONUS assignment due at the end of the semester. It is expected that you will complete EVERY homework assignment on time. Any assignment turned in after the due date and time will receive NO CREDIT. If you are having trouble with Sapling please see me AS SOON AS POSSIBLE so that you do not miss out on points. I strongly discourage you from turning in assignments at the last minute as computer and website problems may occur resulting in late work and missed points. Our section of Genetics has been chosen for the Sapling beta test of their assignments. As such you are provided with access to their site for FREE for the Spring 2015 semester. Additionally, Sapling may be interviewing you individually, via focus groups, or via online surveys to get your thoughts and feelings on the assignments. Your responses will be kept confidential and anonymous and will have NO bearing on your course grade. How to sign up for Sapling: 1. Go to http://saplinglearning.com and click on “US Higher Ed” at the top right. 2a. If you already have a Sapling Learning account, log in and skip to step 3. 2b. If you have a Facebook account, you can use it to quickly create a Sapling Learning account. Click “Create an Account”, then “Create my account through Facebook”. You will be prompted to log into Facebook if you aren't already. Choose a username and password, then click “Link Account”. You can then skip to step 3. 2c. Otherwise, click "Create an Account". Supply the requested information and click "Create My Account". Check your email (and spam filter) for a message from Sapling Learning and click on the link provided in that email. 3. Find your course in the list (you may need to expand the subject and term categories) and click the link. (Abraham Baldwin Agricultural College – BIO 3200 - Spring15 - THURBER) 4. If your course requires a key code, you will be prompted to enter it. 5. If your course requires payment, select a payment option and follow the remaining instructions. Page 3 of 7 3. D2L Quizzes: There will be six (6) quizzes posted on D2L worth 5 points each. Your lowest or missed quiz will be dropped. These quizzes are timed and it is strongly recommended you do not use your notes to answer questions as you need to LEARN the material. Quizzes will be open for 24 hours ending on the day assigned. Please do NOT wait until the last minute to do these quizzes as computer or internet issues may cause you to miss the deadline. NO late credit will be given! 4. Hourly In-Class Exams and Final: There will be five (5) scheduled in-class exams and a cumulative final exam during finals week. Make-up examinations will not be given except under college-valid excused situations. In order to make-up an exam the student must provide the instructor with an obituary notice, legal document, emergency doctor’s note or official letter from ABAC prior to taking the missed exam. Any student who misses an examination should notify the instructor in person or by e-mail prior to the next regularly scheduled class. Absences from a lecture exam will result in a grade of 0 for that exam. Cell phones, pagers, music players, and any electronic communication device must be left in your backpack and all such items must be on mute/silent. The wearing of earbuds is prohibited at any time during class, including during exams. Students may not use programmable calculators on exams. Students may be asked to remove caps or turn them around during testing periods. Students enrolled in classes in the Division of Science and Mathematics will be expected to demonstrate an understanding of subject matter requiring higher order processing skills. Examination questions may include essay, synthesis, analysis, and application: as well as completion, multiple choice, true false, and matching. Computational skills and drawing or diagramming may also be required. 5. Group Oral Presentation and Write-up: Each group of three (3) students will present a PowerPoint presentation on a genetic disorder/mutation of their choosing. Topics will be turned into the instructor by Friday, March 13th. Students will research their topic using a minimum of three (3) sources (journal articles or textbooks). No website will be allowed unless it is in addition to the other sources (must be a reputable website!). The research on the topic will then be used to prepare a 15 minute presentation that should include information on 1) what is this disorder/mutation, 2) what does it affect genotypically, 3) what does it affect phenotypically, 4) what are any possible treatments/ uses, 5) is there any current research on the disorder/mutation, 6) miscellaneous facts. Along with the presentation students should write up a brief summary (2-3 pages, double spaced) that includes a works cited page to be turned into the instructor. Further information about the group presentations will be provided on a handout later in the semester. You will be allowed to choose your own groups and each group member will be asked to ‘rate’ themselves and others based on effort/work put into the project. Academic Policies: Attendance Policy: Courses at Abraham Baldwin Agricultural College (ABAC) are provided for the intellectual growth and development of the students. The interaction with instructors and other students is an important element of the learning process, and a high correlation exists between class attendance and course grades. As such, it is expected that you will attend every class session on time! The instructor will take roll or circulate a sign-in sheet at the beginning of class (~first 10 minutes). Any student not present at the time roll is taken and/or missing a significant portion of Page 4 of 7 class will be counted absent. It is each student’s responsibility to keep up with all classroom activities; lecture notes (oral, written on the board, or on slides); and dates of exams, assignments, quizzes, etc. Additionally, students are expected to be present for EVERY exam session, except under emergency situations. Please come see me or email me if you know you will be missing an exam. I check my email frequently throughout the day between the hours of 7 am and 9 pm; you can expect a response generally within 24 hours (longer on weekends and holidays). Participation Expectations and Conduct: Students are expected to be prepared for class (i.e. bringing a notebook or computer to take notes and their iClicker2, having read the materials prior to class and taken notes), participate actively in the discussion of materials, and be respectful of other people’s contributions and opinions. “An Abraham Baldwin College student is expected to show proper respect for order, morality, and the rights of others. Conduct which is normally reprehensible or which is of a disorderly nature and in violation of written policy shall subject the student to disciplinary action.” Participation includes both asking and answering questions posed during class. Please respect your classmates by not talking over them, ridiculing their contributions, or being disruptive to the discussion. In order to have a fruitful discussion everyone needs to participate and help create an open environment for dialog. Cell Phone Use Policy: Cell phones may NOT be used at any time during class, except to call 911 in case of an emergency. Cell phones may NOT be on the table/desk, your lap, or your hand. Cell phones must be silenced and in your bag or pocket for the duration of the class. Anyone caught with a cell phone out during class will lose that day’s clicker participation points! (This counts as your warning!) Please notify the instructor in advance if an emergency exists where you need your phone. Withdrawal: A student may withdraw from the course up to the midpoint of the semester and receive a grade of W. After midterm, students may withdraw only with permission of the Academic Dean and may receive a grade of WF. A student withdrawing from the lecture must also withdraw from the corequisite lab. Students that stop attending class without officially withdrawing will still receive a grade for the course. Academic Conduct Code: Academic integrity is the responsibility of all ABAC faculty and students. Academic dishonesty and irregularities include, but are not limited to, giving or receiving of unauthorized assistance in the preparation of any academic assignment; taking or attempting to take, stealing, or otherwise obtaining in an unauthorized manner any material pertaining to the education process; selling, giving, lending, or otherwise furnishing to any person any questions and/or answers to any examination known to be scheduled at any subsequent date; fabricating, forging, or falsifying lab or clinical results; plagiarism in any form related to themes, essays, term papers, tests, and other assignments. Academic dishonesty and irregularities will result in a grade of 0 for the assignment and may be subject to disciplinary procedures as outlined in the student handbook. Please check with your course instructor if you have any questions about the conduct code. Page 5 of 7 Tutoring: The AAC is a free tutoring center in the bottom floor of the library. Ask the student at the front desk when tutors are available to help with biology. If you are struggling and not using all the resources available then you are choosing to not succeed. Disability Accommodations: This course fully complies with the accommodations available through the office of disability services. If there is a student in this class who has documented specific needs because of learning disabilities or any other disability; please contact the course instructor immediately to discuss accommodations. Note: The course schedule, policies, procedures, and assessments are subject to change in the event of extraordinary circumstances, by mutual agreement, and/or to ensure better student learning. The instructor reserves the right to make modifications to the schedule and/or syllabus at any time. The lecture topics will be covered in the order listed above and exams will be given on dates specified; however, the instructor may modify the pace at which the material is covered; add or delete material; and/or modify the content covered on each exam. Students are expected to read relevant textbook chapters and/or assigned material prior to each class period. If the campus is closed due to inclement weather or class is officially canceled by the instructor, plan on the missed activities occurring on the next scheduled class day. **Tentative** Course Calendar: The specific dates and amount of time for each lecture topic may vary. The instructor reserves the right to make modifications in the amount of time taken to cover the specific course content and the order in which topics are covered. Class Meeting (Date) Assignmen ts F (1/9) M (1/12) W (1/14) F (1/16) M (1/19) W (1/21) F (1/23) M (1/26) W (1/28) F (1/30) M (2/2) W (2/4) F (2/6) M (2/9) W (2/11) F (2/13) M (2/16) Quiz 1 Topic First day of class; Syllabus review; iClicker2 registration Introduction/ iClicker2 registration Mitosis and Meiosis Mitosis and Meiosis MLK Holiday—No Classes Mendelian Genetics Mendelian Genetics Modification of Mendelian Ratios Modification of Mendelian Ratios Chapters 1 2 2 3 3 4 4 Exam #1 Quiz 2 Sex Determination and Chromosomes Sex Determination and Chromosomes Chromosome Mutations Eukaryotes—linkage and mapping Eukaryotes—linkage and mapping Bacteria and Bacteriophages Exam #2 Page 6 of 7 5 5 6 7 7 8 W (2/18) F (2/20) M (2/23) W (2/25) F (2/27) M (3/2) W (3/4) F (3/6) M (3/9) W (3/11) F (3/13) M (3/16) W (3/18) F (3/20) M (3/23) W (3/25) F (3/27) M (3/30) W (4/1) F (4/3) Quiz 3 Quiz 4 9 9 10 10 11 12 12 Exam #3 Quiz 5 Translation and Proteins Translation and Proteins Gene mutation, DNA repair, Transposition Spring Break—No Classes! Spring Break—No Classes! Spring Break—No Classes! Gene mutation, DNA repair, Transposition Regulation of Gene Expression Regulation of Gene Expression Genetics of Cancer 13 13 14 Developmental Genetics Developmental Genetics Quantitative Genetics Quantitative Genetics Population and Evolutionary Genetics Population and Evolutionary Genetics Conservation Genetics 20 14 15 15 16 Exam #4 M (4/6) W (4/8) F (4/10) M (4/13) W (4/15) F (4/17) M (4/20) W (4/22) F (4/24) M (4/27) W (4/29) M (5/4) DNA Structure and Analysis DNA Structure and Analysis DNA Replication and Recombination DNA Replication and Recombination Chromosome Structure and DNA sequence Genetic Code and Transcription Genetic Code and Transcription Quiz 6 20/21 21 22 22 23 Exam #5 Advanced Topics Presentations Presentations Presentations Presentations Final Exam 10:15a-12:15p Conger 227 Page 7 of 7 17/18/19