Sample Essay using Embedded APA formatting Drosophila larvae deficient in mid-life crisis (micr) function exhibit a decrease in size, in addition to lethality, a locomotory deficit and an aberrant response to light (Scantlebury, 2007). The decrease in size of micr mutants may result from decreased feeding (Scantlebury, 2007) that may in turn be caused by i) neural or ii) muscle defects. A defect in muscle tissue could render the larvae unable to perform the muscle contractions necessary for larval feeding. Conversely, the atypical feeding behavior could be the result of a defect in a neural pathway that innervates the muscle (Hartenstein et al, 1994). Alternatively, an aberration in one of the neural pathways that is responsible for Drosophila appetite could result in decreased larval feeding (Zinke et al., 1999). To investigate whether poor food intake in micr mutants is linked to their size deficit, I performed a series of feeding experiments. Here, I show that micr expression is required in the nervous system for proper feeding and, in turn larval size, to be achieved. References Adrian, TE., Allen, JM., Bloom, SR., Ghatei, MA., Rosor, MN., Roberts, GW., et al. (1983). Neuropeptide-Y distribution in human brain. Nature, 306(5943), 584. Atkinson, W D. (1979). A field investigation of larval competition in domestic drosophila. Journal of Animal Ecology, 48, 91. Bear, M F. (2005). Therapeutic implications of the mGluR theory of fragile X mental retardation. Genes, Brain & Behavior, 4(6), 393-398. Brown, M., Crim, J., Arata, R., Cai, H., Chun, C., & Shen, P. (1999). Identification of a drosophila brain-gut peptide related to the neuropeptide Y family. Peptides, 20(9), 10351042. Busto, M., Iyengar, B., & Campos, A. (1999). Genetic dissection of behavior: Modulation of locomotion by light in the drosophila melanogaster larva requires genetically distinct visual system functions. The Journal of Neuroscience, 19(9), 3337. Dansereau, D., Liu, N., Wilde, A., & Lasko, P. (2005). Midlife crisis is required for germline stem cell maintenance in the ovary [Abstract]. 46th Annual Drosophila Research Conference. San Diego, California. March 30th - April 3rd, Davis, R. L. (2001). Mushroom bodies, Ca2+ oscillations, and the memory gene amnesiac. Neuron, 30(3), 653-656. Duffy, J. B. (2002). GAL4 system in drosophila: A fly geneticist's swiss army knife. Genesis, 34(1-2), 1-15. Duffy, J. B. (2002). GAL4 system in drosophila: A fly geneticist's swiss army knife. Genesis, 34(1-2), 1-15. Erickson, J. C., Clegg, K. E., & Palmiter, R. D. (1996). Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature, 381, 415. Erickson, J., Hollopeter, G., & Palmiter, R. D. (1996). Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y . Science, 274(5293), 1704. Feng, G., Reale, V., Chatwin, H., Kennedy, K., Venard, R., Ericsson, C., et al. (2003). Functional characterization of a neuropeptide F-like receptor from drosophila melanogaster. European Journal of Neuroscience, 18(2), 227-238. Flybase. (1992). Flybase curation. FBrf0105495., 2008, retrieved from http://flybase.bio.indiana.edu.libaccess.lib.mcmaster.ca/reports/FBgn0001122.html