MIAMI-DADE COUNTY PUBLIC SCHOOLS
Student BYOD Resource Page
BIOLOGY I
Course Code: 200031001
TOPIC XXVIII: FACTORS THAT AFFECT HUMAN HEALTH – Genetic Diseases and Human Genetics
Pacing
Date
Traditional 10 Days
Block
ESSENTIAL CONTENT
A. Human Genetic Disorders
1. Molecule to Phenotype
2. Chromosomal Disorders
B. Human Genome
1. Manipulating DNA
2. The Human Genome Project
C. Causes of Genetic diseases
1. Non-disjunction during meiosis
2. Damaged Chromosomes (duplication, deletion,
inversion, and translocation)
3. Gene mutation (e.g. Tay-Sachs disease)
D. Chromosomal Disorders
1. Autosomal Chromosomes (Down Syndrome or
Trisomy 21)
2. Sex Chromosomes (Turner’s Syndrome, Klinefelter’s
Syndrome & other Trisomy conditions)
E. Sex-Linked Genes
1. Definition
2. Disorders (Colorblindness and Hemophilia)
3. Punnett square problems
OBJECTIVES
5 Days
05-28-16 to 06-09-16
05-28-16 to 06-09-16
INSTRUCTIONAL TOOLS
 Recognize that DNA contains hereditary information and Core Text Book: Chapter 14
the importance & application of the Human Genome
Vocabulary: (See p. 2)
Project.
DNA, Sex-linked gene, Nondisjunction, Sex chromosome,
 Describe how chromosomes can be damaged.
Autosome, Dominant, Recessive, Karyotype, Pedigree,
 Identify the gene or chromosomal mutation involved in
Human Genome Project, Duplication, Deletion, Inversion,
human disorders such as Down’s syndrome,
Translocation
Huntington’s disease, Hemophilia and Tay-Sachs
disease.
Technology: (see p.2)
 Recognize disorders caused by sex-linked genes and
1. Untamed Science Video: What Color are My Genes?
predict outcomes using Punnett squares.
2. Art Review: A Human Karyotype
 Identify chromosomal disorders by looking at a
3. Art Review: A Human Karyotype
karyotype.
4. Art in Motion: Non Disjunction Disorders
 Identify types of diseases and/or disorders and list their
effects upon the human body (degenerative, deficiency, 5. Bozeman Podcast: Chromosomal Genetics
6. HippoCampus Biology: Chromosomal Abnormalities
hereditary, and contagious).
7. Edgenuity
 Describe the inheritance of a sex-linked gene such as
8. Extended Learning Modules
color-blindness.
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Student BYOD Resource Page
BIOLOGY I
SC.912.L.16.2
Course Code: 200031001
Human Karyotyping
Video
Standard:
SC.912.L.15.15
Audio
Video
Standard:
SC.912.L.16.2
Audio
 The Human Genome Project
 Heredity: How Our Parents' Genes
Affect Us
 DNA and the Human Genome Project
 Nondisjunction
 Evolution: Sources of Variability:
Recombination
 Choromosomal Alteration That May
 Closing Remarks: Sex-Linked
Occur During Meiosis: Investigating the
Inheritance
Process of Nondisjunction
 The Effects Produced by Chromosomal
 Introduction: Chromosomal Alterations
Alterations
 Discovery of Down Syndrome
 Genetic Disease
 Patterns of Inheritance
 Survey and Data Analysis: Dominant
and Recessive Traits for Hairline,
Thumb, and Earlobes
 Research Results
 Introduction: Sex-Linked Inheritance
 Research on the Genetic Make-up of
the Fruit Fly Drosophila
 Karyotype: A Key to the Study of SexLinked Inheritance
 Evolution: Sources of Genetic
Variability: Mutation
 Heredity: Sex-Linked Genetic
Conditions in Humans
 Inherited Human Traits and Patterned
Sex-Linked Inheritance
 Color Blindness
 Organizing Information About SexLinked Inheritance in Pedigree Charts
 Hemophylia
 Closing Remarks: Sex-Linked
Inheritance
 Heredity: Sex Linkage
 Heredity: Problems Using Sex
Chromosomes & Sex Linkage
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Sex-Linked Traits
Single Gene Disorders
Incomplete Dominance in Snapdragons
Incomplete Dominance in Humans and
Plants
 Reviewing Key Terms That Relate to
Patterns of Inheritance
 Multiple Alleles and Co-Dominance in
Human Blood Types
 Rabbit Breeding
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Student BYOD Resource Page
BIOLOGY I
Standard:
SC.912.L.16.2
Standard:
HE.912.C.1.7
Course Code: 200031001
Image
Video
 Mosaic Down syndrome; nondisjunction
in early embryo
 Human trisomies
 Mutation types; protein changes
 Translocation Mutation
 DNA sequence; nature of mutation
 Base pairing errors; generation of
mutations
 Base substitution mutation
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 Insertion and deletion mutations
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 Down syndrome; distinguishing between 
types
 Mosaic Down syndrome; nondisjunction 
in early embryo
 Down syndrome; mapping effects of

extra DNA
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 Trisomy; gene dosage effects
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 Multifactorial Disorders
 Heredity: How Our Parents' Genes
Affect Us
 Basic Facts About Cancer
 Obesity
 Hunting Down the Genes Involved in
Disease
 DNA and the Genetics of Cancer
 Families and Genetic Disease
 Genetic Case Study: Addison's Disease
 Cystic Fibrosis
 Diabetes
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Human trisomies
X-linked dominant trait; pedigrees
Colorblindness pedigrees; X-linked
recessive trait
Probability of colorblind child - Punnett
square
Probability of colorblind child - answer
Karyotype
Chromosomes
Risk Factors for Heart Disease
DNA Screening
High & Low Risks for Cancer
High & Low Risks for Cardiovascular
Disease
 High & Low Risks for Diabetes
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Student BYOD Resource Page
BIOLOGY I
Course Code: 200031001
Video
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Mapping the Human Genome
No Interest in the Gym? It May Be Genetic
Gene Therapy Offers New Hope to Cancer Patients
Researchers Discover Genes Linked to Deadly Cancers
For Mixed Race Patients, Few Bone Marrow Donors
Researchers Map DNA of Fetus from Blood and Saliva of Parents
Genetic Test Can Help Tailor Breast Cancer Treatment
Cracking the Genetic Code: The First "Book of Life"
Human Chromosome #21 Mapped, Linked to Down Syndrome
Scientists Discover New Gene That Could Help Pinpoint Cause of Alzheimer's Disease
Searching Genes, Genome, for Health Predispositions
Researchers Map First Human Chromosome: #22
"Fountain of Youth" Anti-Aging Gene Found in Earthworms
Dawn of the "Genetics Age" May Help Those With Inherited Diseases
No Bull: Genetic Manipulation Lets Breeders Select for Female Cows
Scientists Isolate Specific Gene That Causes Muscular Dystrophy
Efforts Using Gene-Splicing to Develop Bacteria-Produced Insulin